ATE374784T1 - Lösliche komplexe von zielproteinen und peptidyl- prolyl-isomerase-chaperonen sowie deren herstellung und verwendung - Google Patents
Lösliche komplexe von zielproteinen und peptidyl- prolyl-isomerase-chaperonen sowie deren herstellung und verwendungInfo
- Publication number
- ATE374784T1 ATE374784T1 AT02798355T AT02798355T ATE374784T1 AT E374784 T1 ATE374784 T1 AT E374784T1 AT 02798355 T AT02798355 T AT 02798355T AT 02798355 T AT02798355 T AT 02798355T AT E374784 T1 ATE374784 T1 AT E374784T1
- Authority
- AT
- Austria
- Prior art keywords
- prolyl
- peptidyl
- preparation
- target proteins
- soluble complexes
- Prior art date
Links
- 108010006519 Molecular Chaperones Proteins 0.000 title abstract 2
- 102000005431 Molecular Chaperones Human genes 0.000 title 1
- 102000009658 Peptidylprolyl Isomerase Human genes 0.000 title 1
- 108010020062 Peptidylprolyl Isomerase Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y502/00—Cis-trans-isomerases (5.2)
- C12Y502/01—Cis-trans-Isomerases (5.2.1)
- C12Y502/01008—Peptidylprolyl isomerase (5.2.1.8), i.e. cyclophilin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2002/014631 WO2004056855A1 (en) | 2002-12-20 | 2002-12-20 | Soluble complexes of target proteins and peptidyl prolyl isomerase chaperones and methods of making and using them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE374784T1 true ATE374784T1 (de) | 2007-10-15 |
Family
ID=32668675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02798355T ATE374784T1 (de) | 2002-12-20 | 2002-12-20 | Lösliche komplexe von zielproteinen und peptidyl- prolyl-isomerase-chaperonen sowie deren herstellung und verwendung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1578793B1 (de) |
| JP (1) | JP4459819B2 (de) |
| AT (1) | ATE374784T1 (de) |
| AU (1) | AU2002363891A1 (de) |
| CA (1) | CA2510717C (de) |
| DE (1) | DE60222817T2 (de) |
| ES (1) | ES2294196T3 (de) |
| WO (1) | WO2004056855A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR086250A1 (es) | 2011-05-05 | 2013-11-27 | Hoffmann La Roche | Polipeptido de fusion presentador de una secuencia de aminoacidos y utilizacion del mismo |
| AR093778A1 (es) | 2012-11-08 | 2015-06-24 | Hoffmann La Roche | PROTEINAS LIGANTES DE ANTIGENO ANTI-HER3/HER4 DE UNION A LA HORQUILLA b DE HER3 Y A LA HORQUILLA b DE HER4 |
| JPWO2022045151A1 (de) * | 2020-08-24 | 2022-03-03 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999010374A1 (en) * | 1997-08-26 | 1999-03-04 | Wisconsin Alumni Research Foundation | Cyclosporin a conjugates and uses therefor |
| US5989868A (en) * | 1997-09-12 | 1999-11-23 | The Board Of Regents Of The University Of Oklahoma | Fusion protein systems designed to increase soluble cytoplasmic expression of heterologous proteins in esherichia coli |
| MXPA01004317A (es) * | 1998-10-30 | 2003-06-06 | Jordan L Holtzman | Un complejo de una chaperona con -amiloideo y metodos que emplean este complejo. |
-
2002
- 2002-12-20 AU AU2002363891A patent/AU2002363891A1/en not_active Abandoned
- 2002-12-20 CA CA2510717A patent/CA2510717C/en not_active Expired - Fee Related
- 2002-12-20 AT AT02798355T patent/ATE374784T1/de active
- 2002-12-20 JP JP2004561108A patent/JP4459819B2/ja not_active Expired - Fee Related
- 2002-12-20 WO PCT/EP2002/014631 patent/WO2004056855A1/en not_active Ceased
- 2002-12-20 ES ES02798355T patent/ES2294196T3/es not_active Expired - Lifetime
- 2002-12-20 EP EP02798355A patent/EP1578793B1/de not_active Expired - Lifetime
- 2002-12-20 DE DE60222817T patent/DE60222817T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4459819B2 (ja) | 2010-04-28 |
| CA2510717A1 (en) | 2004-07-08 |
| WO2004056855A1 (en) | 2004-07-08 |
| DE60222817T2 (de) | 2008-07-03 |
| JP2006522583A (ja) | 2006-10-05 |
| EP1578793A1 (de) | 2005-09-28 |
| EP1578793B1 (de) | 2007-10-03 |
| DE60222817D1 (de) | 2007-11-15 |
| AU2002363891A1 (en) | 2004-07-14 |
| ES2294196T3 (es) | 2008-04-01 |
| WO2004056855A9 (en) | 2005-07-14 |
| CA2510717C (en) | 2010-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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