ATE375399T1 - Isolierung von gewebspezifischen peptidliganden und ihre verwendung zur ausrichtung von pharmazeutika auf zielorgane - Google Patents

Isolierung von gewebspezifischen peptidliganden und ihre verwendung zur ausrichtung von pharmazeutika auf zielorgane

Info

Publication number
ATE375399T1
ATE375399T1 AT98908909T AT98908909T ATE375399T1 AT E375399 T1 ATE375399 T1 AT E375399T1 AT 98908909 T AT98908909 T AT 98908909T AT 98908909 T AT98908909 T AT 98908909T AT E375399 T1 ATE375399 T1 AT E375399T1
Authority
AT
Austria
Prior art keywords
isolation
tissue
specific peptide
peptide ligands
target organs
Prior art date
Application number
AT98908909T
Other languages
English (en)
Inventor
Amos Panet
Yocheved Hagai
Janette Lazarovits
Abraham Nimrod
Tikva Vogel
Avigdor Levanon
Elisha Zeelon
Anna Belkind
Itshak Golan
Original Assignee
Savient Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Savient Pharmaceuticals Inc filed Critical Savient Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE375399T1 publication Critical patent/ATE375399T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98908909T 1997-03-04 1998-03-04 Isolierung von gewebspezifischen peptidliganden und ihre verwendung zur ausrichtung von pharmazeutika auf zielorgane ATE375399T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81007497A 1997-03-04 1997-03-04
US3950997P 1997-03-04 1997-03-04

Publications (1)

Publication Number Publication Date
ATE375399T1 true ATE375399T1 (de) 2007-10-15

Family

ID=26716199

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908909T ATE375399T1 (de) 1997-03-04 1998-03-04 Isolierung von gewebspezifischen peptidliganden und ihre verwendung zur ausrichtung von pharmazeutika auf zielorgane

Country Status (7)

Country Link
EP (1) EP0975792B1 (de)
AT (1) ATE375399T1 (de)
AU (1) AU6682598A (de)
CA (1) CA2283474A1 (de)
DE (1) DE69838544T2 (de)
IL (1) IL131655A0 (de)
WO (1) WO1998039469A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9708265D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
EP1167382A1 (de) * 1999-03-31 2002-01-02 Otsuka Pharmaceutical Co., Ltd. Sich an das hämagglutinin des influenzavirus bindendes peptid
GB9912994D0 (en) * 1999-06-07 1999-08-04 Melvin William T Fibrin fragments and therapeutic targets
US6903196B1 (en) 1999-06-17 2005-06-07 Utah Ventures Ii, L.P. Methods for identifying and isolating tissue-specific lumen-exposed molecules
US20030166549A1 (en) * 2000-02-02 2003-09-04 Klaus Schughart Targeting peptides
CZ20021571A3 (cs) * 2000-09-04 2002-09-11 Hyo-Joon Kim Mimetické peptidy k epitopu apolipoproteinu B-110, jejich konkatemer a modifikované peptidy, a vakcinační přípravek, který je obsahuje
US7420030B2 (en) 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
US20040170955A1 (en) 2000-09-08 2004-09-02 Wadih Arap Human and mouse targeting peptides identified by phage display
US7452964B2 (en) 2001-09-07 2008-11-18 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides against placenta and adipose tissues
AU2002323543A1 (en) * 2001-09-07 2003-03-24 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides against placenta and adipose tissues
CN1747747B (zh) 2003-01-06 2012-09-05 安吉奥开米公司 作为穿过血脑屏障的载体的抑酶肽及类似物
JP2006101709A (ja) * 2004-09-30 2006-04-20 Glycomedics Inc ヘマグルチニン結合ペプチド、インフルエンザウイルス感染阻害剤、リポソーム、インフルエンザ治療薬、インフルエンザ予防薬
CN101160403B (zh) 2005-02-18 2014-08-13 安吉奥开米公司 转运化合物穿过血脑屏障的分子
JP5436856B2 (ja) * 2005-07-15 2014-03-05 アンジオケム インコーポレーティッド 薬学的複合体における担体としてのアプロチニンポリペプチドの使用
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
RU2518240C2 (ru) 2008-04-18 2014-06-10 Ангиочем Инк. Композиция, на основе гидрофобных агентов и способ ее получения(варианты)
US8921314B2 (en) 2008-10-15 2014-12-30 Angiochem, Inc. Conjugates of GLP-1 agonists and uses thereof
RU2531591C2 (ru) 2008-10-15 2014-10-20 Ангиокем Инк. Конъюгаты этопозида и доксорубицина для доставки лекарственных средств
MX2011005963A (es) 2008-12-05 2011-09-01 Angiochem Inc Conjugados de neurotensina o analogos de neurotensina y sus usos.
CN102300987A (zh) 2008-12-17 2011-12-28 安吉奥开米公司 膜型-1基质金属蛋白抑制剂及其用途
AU2010239069B2 (en) 2009-04-20 2015-05-14 Angiochem Inc Treatment of ovarian cancer using an anticancer agent conjugated to an Angiopep-2 analog
MX2012000016A (es) 2009-07-02 2012-03-26 Angiochem Inc Conjugados de peptidos multimericos y sus usos.
WO2014026283A1 (en) 2012-08-14 2014-02-20 Angiochem Inc. Peptide-dendrimer conjugates and uses thereof
US10980892B2 (en) 2015-06-15 2021-04-20 Angiochem Inc. Methods for the treatment of leptomeningeal carcinomatosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
WO1994026787A1 (en) * 1993-05-07 1994-11-24 The Board Of Trustees Of The Leland Stanford Junior University Method for generating cell type specific phage antibody libraries
EP0773441B1 (de) * 1995-09-11 2000-08-02 La Jolla Cancer Research Foundation Moleküle, die sich in ausgewählten Organen oder Geweben invivo Einfinden und Verfahren zu ihrer Identifizierung

Also Published As

Publication number Publication date
HK1026234A1 (en) 2000-12-08
AU6682598A (en) 1998-09-22
WO1998039469A1 (en) 1998-09-11
IL131655A0 (en) 2001-01-28
EP0975792A1 (de) 2000-02-02
CA2283474A1 (en) 1998-09-11
DE69838544T2 (de) 2008-07-24
DE69838544D1 (de) 2007-11-22
EP0975792B1 (de) 2007-10-10
EP0975792A4 (de) 2002-12-04

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