ATE37787T1 - Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen. - Google Patents

Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen.

Info

Publication number: ATE37787T1
Authority: AT; Austria
Prior art keywords: hypercorticoidism; diabetes; etiocholanolones; oestrogen; symptoms
Prior art date: 1983-12-28

Application number

AT84115177T

Other languages

English (en)

Inventor

Douglas L Coleman

Norman Applezweig

Original Assignee

Jackson Lab

Progenics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-28

Filing date

1984-12-11

Publication date

1988-10-15

1984-12-11 Application filed by Jackson Lab, Progenics Inc filed Critical Jackson Lab

1988-10-15 Application granted granted Critical

1988-10-15 Publication of ATE37787T1 publication Critical patent/ATE37787T1/de

Links

208000037171 Hypercorticoidism Diseases 0.000 title abstract 2
206010012601 diabetes mellitus Diseases 0.000 title abstract 2
239000000262 estrogen Substances 0.000 title abstract 2
239000000203 mixture Substances 0.000 title 1
230000002195 synergetic effect Effects 0.000 title 1
QGXBDMJGAMFCBF-BNSUEQOYSA-N 3alpha-hydroxy-5beta-androstan-17-one Chemical compound C1[C@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@@H]21 QGXBDMJGAMFCBF-BNSUEQOYSA-N 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
QGXBDMJGAMFCBF-XRJZGPCZSA-N epietiocholanolone Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@@H]21 QGXBDMJGAMFCBF-XRJZGPCZSA-N 0.000 abstract 1
229940011871 estrogen Drugs 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
239000011885 synergistic combination Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT84115177T 1983-12-28 1984-12-11 Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen. ATE37787T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/566,222 US4507289A (en)	1983-12-28	1983-12-28	Treatment of diabetes and other symptoms of hypercorticoidism using a synergistic combination of etiocholanolones and estrogen
EP84115177A EP0148436B1 (de)	1983-12-28	1984-12-11	Behandlung von Diabetes und anderen Symptomen von Hypercorticoidismus unter Verwendung einer synergistischen Mischung von Etiocholanolonen und Oestrogen

Publications (1)

Publication Number	Publication Date
ATE37787T1 true ATE37787T1 (de)	1988-10-15

Family

ID=24262008

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84115177T ATE37787T1 (de)	1983-12-28	1984-12-11	Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen.

Country Status (4)

Country	Link
US (1)	US4507289A (de)
EP (1)	EP0148436B1 (de)
AT (1)	ATE37787T1 (de)
DE (1)	DE3474510D1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4666898A (en) *	1983-12-28	1987-05-19	Jackson Lab.	Treatment of obesity, diabetes and other symptoms of hypercorticoidism using etiocholanolones
US4602008A (en) *	1984-12-14	1986-07-22	Progenics, Inc.	Alkylated etiocholanolones and use as an anti-diabetic, anti-obesity and erythropoietic agent
US4812447A (en) *	1985-10-22	1989-03-14	City Of Hope	Method for the treatment of nervous system degeneration
EP0261891A3 (de) *	1986-09-22	1990-09-05	Progenics, Inc.	Etiochiolandion enthaltende pharmazeutische Zusammensetzungen
NL194728C (nl) *	1987-04-16	2003-01-07	Hollis Eden Pharmaceuticals	Farmaceutisch preparaat geschikt voor de profylaxe of therapie van een retrovirale infectie of een complicatie of gevolg daarvan.
US5006517A (en) *	1987-12-01	1991-04-09	Progenics, Inc.	Treatment of Prader-Willi syndrome
US5753237A (en) *	1989-09-25	1998-05-19	University Of Utah Research Foundation	Method for augmenting immunological responses
AUPN058895A0 (en) *	1995-01-16	1995-02-09	Garvan Institute Of Medical Research	Diagnostic method
JPH10508322A (ja)	1995-10-12	1998-08-18	スーパーゲン，インコーポレイティド	５βステロイドのリポソーム配合物
CA2237023C (en) *	1995-11-13	2008-02-19	Supergen, Inc.	Improved formulation for administration of steroid compounds
US5824668A (en) *	1996-11-07	1998-10-20	Supergen, Inc.	Formulation for administration of steroid compounds
US5635535A (en) *	1996-04-05	1997-06-03	Wagstaff; Robert K.	Method for increasing blood glucose levels
US20030083231A1 (en) *	1998-11-24	2003-05-01	Ahlem Clarence N.	Blood cell deficiency treatment method
US6667299B1 (en)	2000-03-16	2003-12-23	Hollis-Eden Pharmaceuticals, Inc.	Pharmaceutical compositions and treatment methods
AU7896100A (en) *	1999-10-14	2001-04-23	Endorecherche Inc.	Selective estrogen receptor modulators in the treatment or reduction of the riskof acquiring hypertension, cardiovascular diseases, and insulin resistance
RU2251426C1 (ru) *	2003-09-18	2005-05-10	Цыганков Владимир Владимирович	Способ получения инсулина из природного источника и инсулин
US20060234993A1 (en) *	2005-04-13	2006-10-19	Eric Marchewitz	Use of androstane derivatives for enhancing physical performance
WO2011007882A1 (ja) *	2009-07-16	2011-01-20	国立大学法人九州大学	インスリン産生細胞誘導剤、グルコース取込み促進剤および糖尿病または糖尿病合併症の治療薬

1983
- 1983-12-28 US US06/566,222 patent/US4507289A/en not_active Expired - Lifetime
1984
- 1984-12-11 EP EP84115177A patent/EP0148436B1/de not_active Expired
- 1984-12-11 DE DE8484115177T patent/DE3474510D1/de not_active Expired
- 1984-12-11 AT AT84115177T patent/ATE37787T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
US4507289A (en)	1985-03-26
EP0148436B1 (de)	1988-10-12
EP0148436A1 (de)	1985-07-17
DE3474510D1 (en)	1988-11-17

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Legal Events

Date	Code	Title	Description
1989-04-15	UEP	Publication of translation of european patent specification
1990-09-15	REN	Ceased due to non-payment of the annual fee