ATE378060T1 - Verbessertes angereichertes blutplättchen wundheilmittel - Google Patents
Verbessertes angereichertes blutplättchen wundheilmittelInfo
- Publication number
- ATE378060T1 ATE378060T1 AT99938697T AT99938697T ATE378060T1 AT E378060 T1 ATE378060 T1 AT E378060T1 AT 99938697 T AT99938697 T AT 99938697T AT 99938697 T AT99938697 T AT 99938697T AT E378060 T1 ATE378060 T1 AT E378060T1
- Authority
- AT
- Austria
- Prior art keywords
- platele
- wound healer
- enriched
- improved
- wound
- Prior art date
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 150000004492 retinoid derivatives Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Materials For Medical Uses (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9016798P | 1998-06-22 | 1998-06-22 | |
| US9789798P | 1998-08-26 | 1998-08-26 | |
| PCT/US1999/002981 WO1999066797A1 (en) | 1998-06-22 | 1999-02-13 | Enriched platelet wound healant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE378060T1 true ATE378060T1 (de) | 2007-11-15 |
Family
ID=26781976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99938697T ATE378060T1 (de) | 1998-06-22 | 1999-06-21 | Verbessertes angereichertes blutplättchen wundheilmittel |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6303112B1 (de) |
| KR (1) | KR20010071577A (de) |
| AT (1) | ATE378060T1 (de) |
| AU (1) | AU2763099A (de) |
| BR (1) | BR9906477A (de) |
| DE (1) | DE69937562T2 (de) |
| ES (1) | ES2297931T3 (de) |
| MX (1) | MXPA00000009A (de) |
| WO (1) | WO1999066797A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000062828A1 (en) | 1996-04-30 | 2000-10-26 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
| NZ509122A (en) * | 1998-06-22 | 2003-09-26 | Cytomedix Inc | Wound healant comprising activated growth from platelets and ascorbic acid |
| US6524568B2 (en) * | 1998-06-22 | 2003-02-25 | Cytomedix, Inc. | Enriched platelet wound healant |
| GB2369572A (en) | 2000-11-29 | 2002-06-05 | Raft Trustees Ltd | Wound treatment composition comprising insulin |
| EP1420833B1 (de) * | 2001-04-09 | 2010-06-09 | Arteriocyte Medical Systems, Inc. | System zur Herstellung eines Gels aus autologen Blutplättchen |
| US6942880B1 (en) | 2001-04-09 | 2005-09-13 | Medtronic, Inc. | Autologous platelet gel having beneficial geometric shapes and methods of making the same |
| US8101077B2 (en) * | 2001-05-07 | 2012-01-24 | Sivaprasad Sukavaneshvar | Device for separating platelets from fluid suspensions |
| US7011852B2 (en) * | 2001-05-07 | 2006-03-14 | Hemogenesis, Llc | Separation of platelets from whole blood for use as a healant |
| US20030152639A1 (en) * | 2001-07-03 | 2003-08-14 | Calvin Britton | Novel wound healing composition not containing bovine-derived activating reagents |
| EP1429710A1 (de) * | 2001-08-27 | 2004-06-23 | The Cleveland Clinic Foundation | Zusammensetzungen, verfahren und gerät für chirurgische eingriffe |
| US6649072B2 (en) | 2001-11-16 | 2003-11-18 | Robert Brandt | Method for producing autologous platelet-rich plasma |
| TW200505394A (en) * | 2003-06-06 | 2005-02-16 | Asahi Medical Co | Material promoting wound healing |
| US8043614B2 (en) * | 2004-03-09 | 2011-10-25 | Ahlfors Jan-Eric W | Autogenic living scaffolds and living tissue matrices: methods and uses thereof |
| US20050191286A1 (en) * | 2004-02-09 | 2005-09-01 | Gandy James B. | Lyophilized platelet rich plasma for the use in wound healing (chronic or acute) and bone or tissue grafts or repair |
| US20060004189A1 (en) * | 2004-07-02 | 2006-01-05 | James Gandy | Compositions for treating wounds and processes for their preparation |
| US20060142198A1 (en) * | 2004-07-02 | 2006-06-29 | Wound Care Partners Llc | Compositions for treating wounds and processes for their preparation |
| US20070014784A1 (en) * | 2005-06-23 | 2007-01-18 | Medtronic Vascular, Inc. | Methods and Systems for Treating Injured Cardiac Tissue |
| US20100280493A1 (en) * | 2005-06-23 | 2010-11-04 | Asha Nayak | Methods and Systems for Treating Injured Cardiac Tissue |
| US20070093748A1 (en) * | 2005-06-23 | 2007-04-26 | Medtronic Vascular, Inc. | Methods and systems for treating injured cardiac tissue |
| US20070172472A1 (en) * | 2005-06-23 | 2007-07-26 | Asha Nayak | Methods and Systems for Treating Injured Cardiac Tissue |
| CA2612588A1 (en) * | 2005-06-30 | 2007-01-11 | Cytomedix, Inc. | Method for treating wounds with enriched platelet wound healant |
| US9096839B2 (en) | 2006-04-26 | 2015-08-04 | Arteriocyte Medical Systems, Inc. | Compositions and methods of preparation thereof |
| AU2009280612B2 (en) * | 2008-08-11 | 2014-11-13 | Fujimori Kogyo Co., Ltd. | Blood-platelet test method and blood-platelet test device |
| US9227089B1 (en) | 2009-01-14 | 2016-01-05 | Pgfx Patent Holdings, Llc | Skin treatment for promoting hair growth |
| US8734854B2 (en) * | 2009-07-09 | 2014-05-27 | Orogen Biosciences Inc. | Process for removing growth factors from platelets |
| US8454907B2 (en) | 2009-08-12 | 2013-06-04 | Orogen Holdings, Llc | Growth factor extractor |
| US9555171B2 (en) | 2010-09-30 | 2017-01-31 | Depuy Mitek, Llc | Methods and devices for collecting separate components of whole blood |
| CA2829118A1 (en) | 2011-03-09 | 2012-09-13 | Charles E. Worden | Wound healant system and methods of use |
| KR101965592B1 (ko) * | 2011-11-22 | 2019-08-13 | (주)아모레퍼시픽 | 성장 인자를 포함하는 피부 재생 촉진제 |
| EP3568465B1 (de) | 2017-01-11 | 2026-04-15 | FibroBiologics, Inc. | Verfahren zur verbesserung der therapeutischen aktivität von fibroblasten |
| US11364323B2 (en) | 2018-09-17 | 2022-06-21 | Rejuvablast LLC | Combination grafts for tissue repair or regeneration applications |
| GB2579630A (en) | 2018-12-07 | 2020-07-01 | Biotherapy Services Ltd | Methods and compositions |
Family Cites Families (97)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1195061A (en) | 1966-05-27 | 1970-06-17 | Fmc Corp | Coated Structures and Methods of Forming Them. |
| US3883574A (en) | 1971-02-02 | 1975-05-13 | Upjohn Co | Prostaglandin A{HD 3 {B analogs |
| US3948875A (en) | 1973-11-27 | 1976-04-06 | Stanley Cohen | Process for the preparation of epidermal growth factor and new derivative using cross-linked polyacrylamide gel at a pH of 1-3 |
| DE2700043C2 (de) | 1977-01-03 | 1983-12-08 | Thera Gesellschaft für Patentverwertung mbH, 8036 Herrsching | Mittel zur Verbesserung der Durchblutung und Wundheilung |
| US4287184A (en) | 1977-11-23 | 1981-09-01 | The Massachusetts General Hospital | Process for healing wounds |
| DE2902158A1 (de) | 1979-01-20 | 1980-07-31 | Biotest Serum Institut Gmbh | Verfahren zur herstellung von fibrinogen, einem die gerinnungsfaktoren ii, vii, ix und x enthaltenden prothrombinkomplex, antithrombin iii und einer loesung von lagerstabilen serumproteinen |
| AT359653B (de) | 1979-02-15 | 1980-11-25 | Immuno Ag | Verfahren zur herstellung eines gewebekleb- stoffes |
| US4272521A (en) | 1979-07-16 | 1981-06-09 | Cutter Laboratories, Inc. | Purified immune serum globulin |
| US4251510A (en) | 1979-08-15 | 1981-02-17 | Cutter Laboratories, Inc. | Intravenously injectable solution of plasma protein fraction free from bradykinin, kininogen and prekallikrein activators and processes for its production |
| US4512977A (en) | 1979-10-18 | 1985-04-23 | Lundy Research Laboratories, Inc. | Therapeutic selenium compositions and the use thereof |
| FR2533438B2 (fr) | 1979-12-27 | 1986-03-07 | Sederma Sarl | Utilisation en cosmetologie des facteurs de croissance et d'extraits biologiques contenant ceux-ci |
| FR2472385A1 (fr) | 1979-12-27 | 1981-07-03 | Sederma Sa | Nouveaux extraits biologiques utilisables en cosmetologie, et procedes d'obtention de ces extraits |
| US4287180A (en) | 1980-01-28 | 1981-09-01 | Baxter Travenol Laboratories, Inc. | Method for treating blood clotting factor inhibitors |
| US4350687A (en) | 1980-02-10 | 1982-09-21 | Research Corporation | Platelet derived cell growth factor |
| US4273871A (en) | 1980-03-03 | 1981-06-16 | Monsanto Company | Production of angiogenic factor by cell culture |
| US4294826A (en) | 1980-05-07 | 1981-10-13 | Armour Pharmaceutical Company | Process for the preparation of highly purified antihemophilic factor |
| US4296100A (en) | 1980-06-30 | 1981-10-20 | Franco Wayne P | Method of treating the heart for myocardial infarction |
| US4378347A (en) | 1980-06-30 | 1983-03-29 | Franco Wayne P | Composition for treating the heart for myocardial infarction |
| JPS609795B2 (ja) | 1980-12-11 | 1985-03-13 | 株式会社林原生物化学研究所 | ヒト上皮細胞成長因子の製造方法 |
| DE3110610A1 (de) | 1981-03-18 | 1982-10-28 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Chemokinesine und chemotaxine der leukozyten und des entzuendungsgewebes: natuerliche mediatoren zur selektiven reversiblen motilitaetsbeinflussung (chemokinesis) und chemische anlockung (chemotaxis) bei der ansammlung von leukozyten |
| DE3110560A1 (de) | 1981-03-18 | 1982-10-14 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | "angiotropine der leukozyten und des entzuendungsgewebes: eine neue klasse natuerlicher chemotropischer mitogene fuer das richtungswachstum von blutgefaessen und zur neovaskularisierung von geweben" |
| IT1170913B (it) | 1981-04-23 | 1987-06-03 | Manetti & Roberts Italo Brit | Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche |
| US4472523A (en) | 1981-05-22 | 1984-09-18 | Phillips Petroleum Company | Zirconium-titanium catalyzed olefin polymerization |
| DE3171072D1 (en) | 1981-06-25 | 1985-07-25 | Stroetmann M Serapharm | Enriched plasma derivative for promoting wound sealing and wound covering |
| US4479938A (en) | 1981-06-25 | 1984-10-30 | Baxter Travenol Laboratories, Inc. | Therapeutic composition containing factor VIIa |
| ATE20824T1 (de) | 1981-06-25 | 1986-08-15 | Serapharm Gmbh & Co Kg | Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung. |
| US4479896A (en) | 1981-12-11 | 1984-10-30 | Antoniades Harry N | Method for extraction localization and direct recovery of platelet derived growth factor |
| US4431582A (en) | 1981-12-14 | 1984-02-14 | Research Corporation | Protein, composition and method for enhancing epithelial cell movement |
| US5705477A (en) | 1982-09-24 | 1998-01-06 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions of transforming growth factor β(TGF-β) which promotes wound healing and methods for their use |
| US5656587A (en) | 1982-09-24 | 1997-08-12 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Promotion of cell proliferation by use of transforming growth factor beta (TGF-β) |
| EP0105014B1 (de) | 1982-09-24 | 1992-05-20 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Wiederherstellung von Gewebe bei Tieren |
| US4529590A (en) | 1982-12-27 | 1985-07-16 | Leveen Robert F | Production of angiogenetic factor |
| US4470968A (en) | 1983-01-13 | 1984-09-11 | Miles Laboratories, Inc. | Pasteurized therapeutically active blood coagulation factor concentrates |
| US4503038A (en) | 1983-02-25 | 1985-03-05 | The Regents Of The University Of California | Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid |
| CA1230591A (en) | 1983-06-03 | 1987-12-22 | Charles A. Frolik | PURIFIED TRANSFORMING GROWTH FACTOR-.beta. DERIVED FROM HUMAN PLATELETS AND PLACENTAS |
| US4444760A (en) | 1983-06-17 | 1984-04-24 | Merck & Co., Inc. | Purification and characterization of a protein fibroblast growth factor |
| GB2146335A (en) | 1983-09-07 | 1985-04-17 | Ej Ass Inc | Wound healing compositions |
| US4470969A (en) | 1983-12-02 | 1984-09-11 | Miles Laboratories, Inc. | Process for producing a concentrate of coagulation factors VII and VIIa |
| US5165938A (en) * | 1984-11-29 | 1992-11-24 | Regents Of The University Of Minnesota | Wound healing agents derived from platelets |
| AU5249786A (en) | 1985-01-29 | 1986-08-07 | Oncogen | Wound healing compositions |
| US4727137A (en) | 1985-04-17 | 1988-02-23 | President And Fellows Of Harvard College | Purified protein having angiogenic activity and methods of preparation |
| EP0248819B2 (de) | 1985-09-12 | 2000-08-30 | Scios Inc. | Rekombinanter fibroblast-wachstumsfaktor |
| US5904718A (en) | 1986-03-27 | 1999-05-18 | Biocoll Laboratories, Inc. | Delayed drug delivery system |
| US4919939A (en) | 1986-04-29 | 1990-04-24 | Pharmetrix Corporation | Periodontal disease treatment system |
| US5115096A (en) | 1988-04-15 | 1992-05-19 | Oncogen | Amphiregulin: a bifunctional growth modulating glycoprotein |
| US5073114A (en) | 1988-02-23 | 1991-12-17 | Detsch Steven G | Bone growing method and composition |
| US6005162A (en) | 1988-04-20 | 1999-12-21 | Norian Corporation | Methods of repairing bone |
| US5962028A (en) | 1988-04-20 | 1999-10-05 | Norian Corporation | Carbonated hydroxyapatite compositions and uses |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| ES2051968T3 (es) | 1988-12-22 | 1994-07-01 | American Cyanamid Co | Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion. |
| US5226877A (en) | 1989-06-23 | 1993-07-13 | Epstein Gordon H | Method and apparatus for preparing fibrinogen adhesive from whole blood |
| US5077049A (en) | 1989-07-24 | 1991-12-31 | Vipont Pharmaceutical, Inc. | Biodegradable system for regenerating the periodontium |
| WO1991001720A1 (en) | 1989-08-07 | 1991-02-21 | Herman Wade Schlameus | Composition and method of promoting hard tissue healing |
| US5158934A (en) | 1989-09-01 | 1992-10-27 | Genentech, Inc. | Method of inducing bone growth using TGF-β |
| US5422340A (en) | 1989-09-01 | 1995-06-06 | Ammann; Arthur J. | TGF-βformulation for inducing bone growth |
| US5599558A (en) | 1989-09-15 | 1997-02-04 | Curative Technologies, Inc. | Selecting amounts of platelet releasate for efficacious treatment of tissue |
| US5686116A (en) | 1990-01-12 | 1997-11-11 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Methods of enhancing repair, healing and augmentation of bone implants |
| US5155038A (en) | 1990-02-22 | 1992-10-13 | W. R. Grace & Co.-Conn. | Use of thrombospondin to promote wound healing |
| US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
| US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US5863938A (en) | 1991-03-01 | 1999-01-26 | Warner Lambert Company | Antibacterial-wound healing compositions and methods for preparing and using same |
| US5658956A (en) | 1991-03-01 | 1997-08-19 | Warner-Lambert Company | Bioadhesive-wound healing compositions and methods for preparing and using same |
| US5856364A (en) | 1991-03-01 | 1999-01-05 | Warner Lambert Company | Therapeutic antiviral-wound healing compositions and methods for preparing and using same |
| US5874479A (en) | 1991-03-01 | 1999-02-23 | Warner-Lambert Company | Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same |
| US5674912A (en) * | 1991-03-01 | 1997-10-07 | Warner-Lambert Company | Sunscreen-wound healing compositions and methods for preparing and using same |
| US5658957A (en) | 1991-03-01 | 1997-08-19 | Warner Lambert Company | Immunostimulating wound healing compositions and method for preparing and using same |
| US5648380A (en) | 1991-03-01 | 1997-07-15 | Warner-Lambert Company | Anti-inflammatory wound healing compositions and methods for preparing and using same |
| US5692302A (en) | 1991-03-01 | 1997-12-02 | Warner-Lambert Company | Razor cartridges comprising wound healing compositions and methods for preparing and using same |
| US5981606A (en) * | 1991-03-01 | 1999-11-09 | Warner-Lambert Company | Therapeutic TGF-beta-wound healing compositions and methods for preparing and using same |
| US5149691A (en) | 1991-03-12 | 1992-09-22 | Creative Biomolecules, Inc. | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
| SG47470A1 (en) | 1991-04-25 | 1998-04-17 | Univ Brown Res Found | Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products |
| FR2696095B1 (fr) | 1992-09-30 | 1994-11-25 | Inoteb | Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application. |
| DE69530914T2 (de) * | 1994-02-17 | 2004-03-11 | New York Blood Center, Inc. | Biologische bioadhäsive präparate, die fibrinkleber und liposomen enthalten, verfahren für ihre herstellung und verwendung |
| FR2718023B1 (fr) | 1994-03-30 | 1996-08-14 | Paris Val Marne Universite | Médicament et composition pharmaceutique pour le traitement de lésions du tractus digestif. |
| WO1995029686A1 (en) | 1994-05-02 | 1995-11-09 | E.R. Squibb & Sons, Inc. | Recombinant fibrin chains, fibrin and fibrin-homologs |
| WO1995031223A1 (en) | 1994-05-13 | 1995-11-23 | Kuraray Co., Ltd. | Medical polymer gel |
| US5817327A (en) | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| US5891558A (en) | 1994-11-22 | 1999-04-06 | Tissue Engineering, Inc. | Biopolymer foams for use in tissue repair and reconstruction |
| US5585007A (en) * | 1994-12-07 | 1996-12-17 | Plasmaseal Corporation | Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant |
| US5733545A (en) * | 1995-03-03 | 1998-03-31 | Quantic Biomedical Partners | Platelet glue wound sealant |
| US5580923A (en) | 1995-03-14 | 1996-12-03 | Collagen Corporation | Anti-adhesion films and compositions for medical use |
| US5900245A (en) | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
| US5612052A (en) | 1995-04-13 | 1997-03-18 | Poly-Med, Inc. | Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof |
| US5661127A (en) | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
| US5910492A (en) | 1995-06-05 | 1999-06-08 | Takeda Chemical Industries, Ltd. | Osteogenic promoting pharmaceutical composition |
| US6071284A (en) | 1995-10-30 | 2000-06-06 | Biomedical Enterprises, Inc. | Materials collection system and uses thereof |
| US5733884A (en) | 1995-11-07 | 1998-03-31 | Nestec Ltd. | Enteral formulation designed for optimized wound healing |
| BR9509985A (pt) | 1995-12-12 | 1998-11-03 | Omeros Med Sys Inc | Solução para irrigação e método para inibição de dor inflamação e esparmo |
| US6048964A (en) | 1995-12-12 | 2000-04-11 | Stryker Corporation | Compositions and therapeutic methods using morphogenic proteins and stimulatory factors |
| PT876165E (pt) | 1995-12-18 | 2006-10-31 | Angiotech Biomaterials Corp | Composicoes de polimeros reticulados e processos para a sua utilizacao |
| AU3214797A (en) | 1996-05-28 | 1998-01-05 | Regents Of The University Of Michigan, The | Engineering oral tissues |
| GB9701552D0 (en) | 1997-01-25 | 1997-03-12 | Bristol Myers Squibb Co | Multi-dose wound gel |
| US6001352A (en) | 1997-03-31 | 1999-12-14 | Osteobiologics, Inc. | Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor |
| US5861149A (en) * | 1997-06-04 | 1999-01-19 | Polyheal Ltd. | Methods for wound treatment |
| US6015474A (en) | 1997-06-20 | 2000-01-18 | Protein Polymer Technologies | Methods of using primer molecules for enhancing the mechanical performance of tissue adhesives and sealants |
| US5899939A (en) | 1998-01-21 | 1999-05-04 | Osteotech, Inc. | Bone-derived implant for load-supporting applications |
| US6056970A (en) | 1998-05-07 | 2000-05-02 | Genzyme Corporation | Compositions comprising hemostatic compounds and bioabsorbable polymers |
-
1999
- 1999-02-13 WO PCT/US1999/002981 patent/WO1999066797A1/en not_active Ceased
- 1999-02-13 AU AU27630/99A patent/AU2763099A/en not_active Abandoned
- 1999-02-13 MX MXPA00000009A patent/MXPA00000009A/es active IP Right Grant
- 1999-06-21 KR KR1020007014648A patent/KR20010071577A/ko not_active Withdrawn
- 1999-06-21 ES ES99938697T patent/ES2297931T3/es not_active Expired - Lifetime
- 1999-06-21 DE DE69937562T patent/DE69937562T2/de not_active Expired - Lifetime
- 1999-06-21 BR BR9906477-4A patent/BR9906477A/pt not_active Application Discontinuation
- 1999-06-21 AT AT99938697T patent/ATE378060T1/de active
- 1999-11-23 US US09/424,523 patent/US6303112B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2297931T3 (es) | 2008-05-01 |
| AU2763099A (en) | 2000-01-10 |
| BR9906477A (pt) | 2000-09-26 |
| DE69937562T2 (de) | 2008-10-23 |
| DE69937562D1 (de) | 2007-12-27 |
| KR20010071577A (ko) | 2001-07-28 |
| MXPA00000009A (es) | 2005-09-08 |
| WO1999066797A1 (en) | 1999-12-29 |
| US6303112B1 (en) | 2001-10-16 |
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