ATE378082T1 - Gerät zur abgabe einer festen medikamentenzusammensetzung - Google Patents

Gerät zur abgabe einer festen medikamentenzusammensetzung

Info

Publication number
ATE378082T1
ATE378082T1 AT04019495T AT04019495T ATE378082T1 AT E378082 T1 ATE378082 T1 AT E378082T1 AT 04019495 T AT04019495 T AT 04019495T AT 04019495 T AT04019495 T AT 04019495T AT E378082 T1 ATE378082 T1 AT E378082T1
Authority
AT
Austria
Prior art keywords
dispensing
microplunger
solid drug
solid medication
medication composition
Prior art date
Application number
AT04019495T
Other languages
English (en)
Inventor
Roland Cherif-Cheikh
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of ATE378082T1 publication Critical patent/ATE378082T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31531—Microsyringes, e.g. having piston bore diameter close or equal to needle shaft diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04019495T 1994-09-02 1995-08-31 Gerät zur abgabe einer festen medikamentenzusammensetzung ATE378082T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/300,713 US5582591A (en) 1994-09-02 1994-09-02 Delivery of solid drug compositions
US31746594A 1994-10-04 1994-10-04

Publications (1)

Publication Number Publication Date
ATE378082T1 true ATE378082T1 (de) 2007-11-15

Family

ID=26971933

Family Applications (3)

Application Number Title Priority Date Filing Date
AT04019495T ATE378082T1 (de) 1994-09-02 1995-08-31 Gerät zur abgabe einer festen medikamentenzusammensetzung
AT95930675T ATE230977T1 (de) 1994-09-02 1995-08-31 Verabreichung von festen arzneizubereitungen
AT02017692T ATE280599T1 (de) 1994-09-02 1995-08-31 Gerät zur parenteralen abgabe fester wirkstoffzusammensetzungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT95930675T ATE230977T1 (de) 1994-09-02 1995-08-31 Verabreichung von festen arzneizubereitungen
AT02017692T ATE280599T1 (de) 1994-09-02 1995-08-31 Gerät zur parenteralen abgabe fester wirkstoffzusammensetzungen

Country Status (15)

Country Link
US (2) US5582591A (de)
EP (3) EP1270032B1 (de)
JP (1) JP4072867B2 (de)
KR (1) KR100491424B1 (de)
CN (1) CN1212830C (de)
AT (3) ATE378082T1 (de)
AU (1) AU712916B2 (de)
BR (1) BR9508688A (de)
CA (1) CA2198916C (de)
DE (3) DE69535645T2 (de)
DK (2) DK0778767T3 (de)
ES (3) ES2188669T3 (de)
PT (2) PT1498150E (de)
WO (1) WO1996007397A2 (de)
ZA (1) ZA957356B (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
WO1997045105A1 (en) 1996-05-24 1997-12-04 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating or preventing diseases of body passageways
FR2756493B1 (fr) 1996-12-02 2001-04-13 Delab Dispositif d'administration locale de formulations solides ou semi-solides
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
SE9700423D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Disposable inhaler
FR2783433B1 (fr) * 1998-09-18 2001-02-16 Delab Seringues pour l'administration de formulations pateuses ou semi-solides
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
AU3957400A (en) 1999-04-16 2000-11-02 Novo Nordisk A/S Dry, mouldable drug formulation
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
PT1242055E (pt) * 1999-12-23 2008-07-02 Pfizer Prod Inc Forma de dosagem de fármaco baseada em hidrogel
US20010041869A1 (en) * 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
US20050008683A1 (en) * 2000-06-29 2005-01-13 Becton Dickinson And Company Method for delivering interferons to the intradermal compartment
US20040175360A1 (en) * 2000-06-29 2004-09-09 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
EP1313425B1 (de) * 2000-07-14 2007-03-07 Novo Nordisk A/S Verfahren zum formen einer pharmazeutischen zusammensetzung in einem verpackungsmaterial
EP1381423A1 (de) * 2001-04-13 2004-01-21 Becton, Dickinson and Company Verfahren und vorrichtung zur intradermale abgabe von substanzen für systemischer absorption
US20050010193A1 (en) * 2002-05-06 2005-01-13 Laurent Philippe E. Novel methods for administration of drugs and devices useful thereof
EP1416986A4 (de) 2001-06-29 2005-12-14 Becton Dickinson Co Intradermale freisetzung von vakzinen und gentherapeutischen mitteln mit einer mikrokanüle
US20030073609A1 (en) * 2001-06-29 2003-04-17 Pinkerton Thomas C. Enhanced pharmacokinetic profile of intradermally delivered substances
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
US8454997B2 (en) 2001-12-18 2013-06-04 Novo Nordisk A/S Solid dose micro implant
US20060264886A9 (en) * 2002-05-06 2006-11-23 Pettis Ronald J Method for altering insulin pharmacokinetics
AU2003230256B2 (en) * 2002-05-06 2009-06-04 Becton, Dickinson And Company Method and device for controlling drug pharmacokinetics
US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
WO2004020014A2 (en) * 2002-08-30 2004-03-11 Becton, Dickinson And Company Method of controlling pharmacokinetics of immunomodulatory compounds
CN1723053A (zh) * 2002-09-12 2006-01-18 儿童医院医疗中心 无痛药物注射的方法和设备
DK1581251T3 (da) 2002-12-31 2016-06-27 Althea Tech Inc Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf
JP4565193B2 (ja) 2003-04-23 2010-10-20 バレリタス， インコーポレイテッド 長い持続時間の医薬投与のための液圧作動式ポンプ
AU2004264839B2 (en) * 2003-06-13 2009-06-04 Becton, Dickinson And Company Improved intra-dermal delivery of biologically active agents
BRPI0414014A (pt) * 2003-08-26 2006-10-24 Becton Dickinson Co métodos para distribuição intradérmica de agentes terapêuticos
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto injector
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
US7896841B2 (en) * 2004-02-17 2011-03-01 Children's Hospital Medical Center Injection device for administering a vaccine
WO2005091922A2 (en) * 2004-03-03 2005-10-06 Becton, Dickinson And Company Methods and devices for improving delivery of a substance to skin
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
WO2005115360A2 (en) * 2004-05-11 2005-12-08 Becton, Dickinson And Company Formulations of anti-pain agents and methods of using the same
WO2006014425A1 (en) 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
JP4913030B2 (ja) * 2005-01-31 2012-04-11 株式会社バイオセレンタック 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具
EP1704883B1 (de) * 2005-03-24 2008-11-12 Disetronic Licensing AG Vorrichtung für die dosierte Verabreichung eines fluiden Produkts
DE502005005948D1 (de) * 2005-03-24 2008-12-24 Disetronic Licensing Ag Vorrichtung für die dosierte Verabreichung eines fluiden Produkts
EP1704885A1 (de) * 2005-03-24 2006-09-27 Disetronic Licensing AG Vorrichtung für die dosierte Verabreichung eines fluiden Produkts
EP1704886B1 (de) * 2005-03-24 2008-02-06 Disetronic Licensing AG Vorrichtung für die dosierte Verabreichung eines fluiden Produkts
WO2007075839A2 (en) * 2005-12-19 2007-07-05 Diobex, Inc. Glucagon injector for emergency treatment of hypoglycemia
US12151080B2 (en) * 2006-02-09 2024-11-26 Deka Products Limited Partnership Adhesive and peripheral systems and methods for medical devices
EP1997233B1 (de) 2006-03-13 2014-03-05 Novo Nordisk A/S Sichere paarung elektronischer geräte mittels zweifacher kommunikationsmittel
ES2656675T3 (es) 2006-03-30 2018-02-28 Valeritas, Inc. Dispositivo de suministro de fluidos de múltiples cartuchos
WO2007141210A1 (en) 2006-06-06 2007-12-13 Novo Nordisk A/S Assembly comprising skin-mountable device and packaging therefore
US8668676B2 (en) * 2006-06-19 2014-03-11 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
WO2008008008A1 (en) * 2006-07-13 2008-01-17 St. Jude Medical Ab Information management in devices worn by a use
US9039761B2 (en) * 2006-08-04 2015-05-26 Allergan, Inc. Ocular implant delivery assemblies with distal caps
CN101641123A (zh) * 2007-03-06 2010-02-03 诺沃-诺迪斯克有限公司 包括操作机构系统的泵组件
US8529521B2 (en) * 2007-04-23 2013-09-10 Ultimed Inc. Low-dosage syringe
DK2200684T3 (en) 2007-08-17 2016-12-12 Medtronic Minimed Inc Injection device for making an injection in a pre-determined depth in the skin
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
US8545554B2 (en) 2009-01-16 2013-10-01 Allergan, Inc. Intraocular injector
AU2010217760B2 (en) 2009-02-27 2015-04-09 Tandem Diabetes Care, Inc. Methods and devices for determination of flow reservoir volume
US9250106B2 (en) 2009-02-27 2016-02-02 Tandem Diabetes Care, Inc. Methods and devices for determination of flow reservoir volume
US20120109046A1 (en) * 2009-03-27 2012-05-03 Novo Nordisk A/S Solid dose delivery device
US20110152770A1 (en) 2009-07-30 2011-06-23 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
WO2011046857A1 (en) * 2009-10-15 2011-04-21 Mallinckrodt Inc. Piezoelectrically-driven power injector
EP2452638A1 (de) * 2010-11-15 2012-05-16 forteq Nidau AG Vorrichtung zur Feststoffinjektion
WO2012125999A2 (en) * 2011-03-17 2012-09-20 Emory University Delivery devices and methods for delivering therapeutic agents
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
EP2968695A1 (de) * 2013-03-14 2016-01-20 Allergan, Inc. Polymersystem zum befestigen von implantaten in spritzennadeln
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
GB2545880A (en) * 2015-10-20 2017-07-05 Glide Pharmaceutical Tech Ltd Solid formulation
JP2020528296A (ja) 2017-07-25 2020-09-24 アムジエン・インコーポレーテツド ギヤモジュールを有する薬物送達デバイス及び関連する組立方法
AU2020280117B2 (en) * 2019-05-20 2023-04-06 The University Of Sydney An adaptor for a medicament delivery device and a related method
US11585042B2 (en) 2020-09-30 2023-02-21 Haier Us Appliance Solutions, Inc. Dryer appliance with additive dispenser
GB202200706D0 (en) * 2022-01-20 2022-03-09 Cambridge Univ Hospitals Nhs Foundation Trust A surgical instrument
CN115089851B (zh) * 2022-06-21 2025-06-13 上海力声特医学科技有限公司 一种可持续给药的人工耳蜗植入体

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2513014A (en) * 1946-11-18 1950-06-27 Abbott Lab Apparatus for implanting medicinal pellets subcutaneously
US3760806A (en) * 1971-01-13 1973-09-25 Alza Corp Helical osmotic dispenser with non-planar membrane
US3995631A (en) * 1971-01-13 1976-12-07 Alza Corporation Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient
US4177256A (en) * 1973-04-25 1979-12-04 Alza Corporation Osmotic bursting drug delivery device
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
FR2239989A1 (en) * 1973-08-08 1975-03-07 Aries Robert Pellets for subcutaneous treatment of animals - pref. implanted from a cartridge contg. several, by means of an injection force
US4142526A (en) * 1974-12-23 1979-03-06 Alza Corporation Osmotic releasing system with means for changing release therefrom
US4273122A (en) * 1976-11-12 1981-06-16 Whitney Douglass G Self contained powered injection system
US4086914A (en) * 1977-02-11 1978-05-02 Edwin Bailey Moore Implant injector
US4263910A (en) * 1978-09-27 1981-04-28 Eli Lilly And Company Implantate package, system and method
US4313439A (en) * 1980-03-24 1982-02-02 Biotek, Inc. Automated, spring-powered medicament infusion system
CA1174284A (en) * 1980-09-02 1984-09-11 Medtronic, Inc. Body implantable lead
US4326524A (en) * 1980-09-30 1982-04-27 Minnesota Mining And Manufacturing Company Solid dose ballistic projectile
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4451253A (en) * 1980-12-18 1984-05-29 Harman Sherman M Means and method for administering medicinals
US4340054A (en) * 1980-12-29 1982-07-20 Alza Corporation Dispenser for delivering fluids and solids
US4525164A (en) * 1981-04-24 1985-06-25 Biotek, Inc. Wearable medication infusion system with arcuated reservoir
US4529401A (en) * 1982-01-11 1985-07-16 Cardiac Pacemakers, Inc. Ambulatory infusion pump having programmable parameters
DE3317536A1 (de) * 1983-05-13 1984-11-15 Siemens AG, 1000 Berlin und 8000 München Dosiervorrichtung fuer ein medikament
CA1196864A (en) * 1983-06-10 1985-11-19 Mattheus F.A. Goosen Controlled release of injectable and implantable insulin compositions
US4753636A (en) * 1983-08-02 1988-06-28 Endocon, Inc. Subcutaneous implant kit
EP0139286B1 (de) * 1983-10-14 1991-08-21 Sumitomo Pharmaceuticals Company, Limited Verlängerte Präparate mit verzögerter Abgabe
US4685903A (en) * 1984-01-06 1987-08-11 Pacesetter Infusion, Ltd. External infusion pump apparatus
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
GB8423749D0 (en) * 1984-09-19 1984-10-24 Sutherland I A Powered infusion apparatus
US4720384A (en) * 1985-05-03 1988-01-19 E. I. Du Pont De Nemours And Company Manufacture of hollow fine tubular drug delivery systems
US4655766A (en) * 1985-08-01 1987-04-07 Alza Corporation Fluid imbibing pump with self-regulating skin patch
EP0230647B1 (de) * 1985-12-27 1993-03-31 Sumitomo Pharmaceuticals Company, Limited Verfahren zur Herstellung einer Formulierung mit verzögerter Freisetzung
US4661103A (en) * 1986-03-03 1987-04-28 Engineering Development Associates, Ltd. Multiple implant injector
US4723958A (en) * 1986-05-23 1988-02-09 Merck & Co., Inc. Pulsatile drug delivery system
EP0402955B1 (de) * 1986-07-30 1994-03-09 Sumitomo Pharmaceuticals Company, Limited Verabreichungsinstrument zum Einführen von festen Medikamenten
US4693706A (en) * 1986-08-11 1987-09-15 Mark L. Anderson Two compartment mixing syringe
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
US4994028A (en) * 1987-03-18 1991-02-19 Endocon, Inc. Injector for inplanting multiple pellet medicaments
DE3855054T2 (de) * 1987-05-26 1996-07-18 Nissho Kk Vorrichtung zur Verabreichung von festen Präparaten
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
DE3802158A1 (de) * 1987-08-11 1989-02-23 Hoechst Ag Vorrichtung zur applikation von implantaten
US4936827A (en) * 1988-04-11 1990-06-26 Ivy Laboratories, Inc. Implanter applicator
US4834704A (en) * 1988-04-13 1989-05-30 Eaton Corporation Injectable infusion pump apparatus for implanting long-term dispensing module and medication in an animal and method therefor
US4976966A (en) * 1988-12-29 1990-12-11 Alza Corporation Delayed release osmotically driven fluid dispenser
US5226895A (en) * 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
US5284479A (en) * 1989-08-30 1994-02-08 N.V. Nederlandsche Apparatenfabriek Nedap Implanter
US5086787A (en) * 1989-12-06 1992-02-11 Medtronic, Inc. Steroid eluting intramuscular lead
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
KR930001079B1 (ko) * 1990-07-18 1993-02-15 한국과학기술연구원 자가 방출 조절형 인슐린 제형
KR930008048B1 (ko) * 1991-06-05 1993-08-25 윤영우 요청신호개수에 독립적인 중재시간의 중재기
IL105553A (en) * 1992-05-06 1998-01-04 Janssen Pharmaceutica Inc Solid dosage form comprising a porous network of matrix forming material which disperses rapidly in water
JPH0631181A (ja) * 1992-07-06 1994-02-08 Stonehard Assoc Inc 高分散金属微粒子担持触媒の製造方法
DK42093D0 (da) * 1993-04-07 1993-04-07 Bukh Meditec Administrationsmetode
ES2183867T3 (es) * 1994-02-18 2003-04-01 Solidose L L C Inoculacion de animales con materiales biologicos secados en peletes.

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DE69529415D1 (de) 2003-02-20
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WO1996007397A2 (en) 1996-03-14
DE69533709T2 (de) 2005-10-20
ZA957356B (en) 1996-04-02
PT1498150E (pt) 2008-02-19
DE69535645T2 (de) 2008-10-30
AU3398195A (en) 1996-03-27
PT1270032E (pt) 2005-02-28
KR100491424B1 (ko) 2005-05-24
JPH10508293A (ja) 1998-08-18
DE69533709D1 (de) 2004-12-02
US5582591A (en) 1996-12-10
WO1996007397A3 (en) 1996-08-15
ATE230977T1 (de) 2003-02-15
BR9508688A (pt) 1997-10-28
EP1270032B1 (de) 2004-10-27
EP0778767A2 (de) 1997-06-18
CA2198916C (en) 2008-07-22
EP0778767B1 (de) 2003-01-15
KR20030096434A (ko) 2003-12-31
JP4072867B2 (ja) 2008-04-09
DK0778767T3 (da) 2003-04-07
CN1212830C (zh) 2005-08-03
CA2198916A1 (en) 1996-03-14
DE69535645D1 (de) 2007-12-27
AU712916B2 (en) 1999-11-18
EP1498150A1 (de) 2005-01-19
DK1270032T3 (da) 2005-01-31
EP1270032A1 (de) 2003-01-02
ES2188669T3 (es) 2003-07-01
US5616123A (en) 1997-04-01
EP1498150B1 (de) 2007-11-14
DE69529415T2 (de) 2003-11-13
CN1165477A (zh) 1997-11-19
ES2295745T3 (es) 2008-04-16
ES2230431T3 (es) 2005-05-01

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