ATE378426T1 - Neue sequenz um die expression einer nukleinsäure zu erhöhen - Google Patents

Neue sequenz um die expression einer nukleinsäure zu erhöhen

Info

Publication number
ATE378426T1
ATE378426T1 AT05756870T AT05756870T ATE378426T1 AT E378426 T1 ATE378426 T1 AT E378426T1 AT 05756870 T AT05756870 T AT 05756870T AT 05756870 T AT05756870 T AT 05756870T AT E378426 T1 ATE378426 T1 AT E378426T1
Authority
AT
Austria
Prior art keywords
expression
nucleic acid
increase
new sequence
repressor
Prior art date
Application number
AT05756870T
Other languages
English (en)
Inventor
Arie Otte
Theodorus Kwaks
Richard George Antonius Sewalt
Blokland Henricus Johannes Van
Original Assignee
Chromagenics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971366&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE378426(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chromagenics Bv filed Critical Chromagenics Bv
Application granted granted Critical
Publication of ATE378426T1 publication Critical patent/ATE378426T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05756870T 2004-07-08 2005-07-07 Neue sequenz um die expression einer nukleinsäure zu erhöhen ATE378426T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58700704P 2004-07-08 2004-07-08
EP2004051405 2004-07-08

Publications (1)

Publication Number Publication Date
ATE378426T1 true ATE378426T1 (de) 2007-11-15

Family

ID=34971366

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05756870T ATE378426T1 (de) 2004-07-08 2005-07-07 Neue sequenz um die expression einer nukleinsäure zu erhöhen

Country Status (19)

Country Link
US (1) US7825232B2 (de)
JP (1) JP4805262B2 (de)
KR (1) KR101188013B1 (de)
CN (1) CN1981057B (de)
AT (1) ATE378426T1 (de)
AU (1) AU2005261699B2 (de)
BR (1) BRPI0512798A (de)
CA (1) CA2573022C (de)
DE (1) DE602005003369T2 (de)
DK (1) DK1763586T3 (de)
EA (1) EA011747B1 (de)
ES (1) ES2296201T3 (de)
IL (1) IL180531A (de)
MX (1) MXPA06014553A (de)
NO (1) NO341862B1 (de)
NZ (1) NZ551510A (de)
PT (1) PT1763586E (de)
WO (1) WO2006005718A2 (de)
ZA (1) ZA200610470B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE354645T1 (de) 2002-12-20 2007-03-15 Chromagenics Bv Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können
CN101090968B (zh) * 2004-11-08 2011-10-26 科罗迈吉尼科斯公司 高水平表达蛋白质的宿主细胞的选择
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
US20100136616A1 (en) * 2004-11-08 2010-06-03 Chromagenics B.V. Selection of Host Cells Expressing Protein at High Levels
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
PL1809750T3 (pl) * 2004-11-08 2012-08-31 Chromagenics Bv Selekcja komórki gospodarza eksprymującej białko na wysokich poziomach
EP2443239B1 (de) 2009-06-15 2015-11-25 Cellagenics B.V. Neue stringent selektionsmarker
US9790517B2 (en) 2010-06-15 2017-10-17 Cellagenics B.V. Intergenic elements for enhancing gene expression
US9650630B2 (en) 2010-09-01 2017-05-16 Cellagenics B.V. Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression
CN110484563B (zh) * 2019-07-25 2023-04-07 新乡医学院 哺乳动物细胞组合表达载体、表达系统、制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1806407B1 (de) 2001-07-04 2010-05-05 Chromagenics B.V. DNS-Sequenzen mit Anti-Repressor-Aktivität
DK1513937T3 (da) * 2002-06-14 2011-05-16 Chromagenics Bv Fremgangsmåde til den samtidige produktion af multiple proteiner; vektorer og celler til anvendelse derved
ATE354645T1 (de) 2002-12-20 2007-03-15 Chromagenics Bv Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können

Also Published As

Publication number Publication date
CN1981057A (zh) 2007-06-13
JP4805262B2 (ja) 2011-11-02
IL180531A0 (en) 2007-06-03
AU2005261699A1 (en) 2006-01-19
EA200700233A1 (ru) 2007-06-29
NO341862B1 (no) 2018-02-12
CN1981057B (zh) 2012-07-04
KR101188013B1 (ko) 2012-10-08
DK1763586T3 (da) 2008-03-17
ZA200610470B (en) 2008-09-25
US7825232B2 (en) 2010-11-02
AU2005261699B2 (en) 2009-07-23
JP2008505626A (ja) 2008-02-28
PT1763586E (pt) 2008-02-25
WO2006005718A3 (en) 2006-08-17
EA011747B1 (ru) 2009-06-30
NZ551510A (en) 2009-10-30
DE602005003369D1 (de) 2007-12-27
CA2573022C (en) 2012-03-06
IL180531A (en) 2011-04-28
ES2296201T3 (es) 2008-04-16
HK1097004A1 (en) 2007-06-15
CA2573022A1 (en) 2006-01-19
US20070212755A1 (en) 2007-09-13
BRPI0512798A (pt) 2008-04-08
KR20070042122A (ko) 2007-04-20
DE602005003369T2 (de) 2009-03-05
WO2006005718A2 (en) 2006-01-19
NO20070757L (no) 2007-02-08
MXPA06014553A (es) 2007-03-12

Similar Documents

Publication Publication Date Title
NO20070757L (no) Ny sekvens for forbedring av ekspresjon av nukleinsyre(r)
DK1836299T4 (da) Polypeptider, der har cellobiohydrolaseaktivitet, og polynukleotider, der koder for disse
DK1448595T3 (da) Antimikrobielle polypeptider
DK1578964T4 (da) Polypeptider med cellobiohydrolase II-aktivitet og polynukleotider, der koder for samme
CR9969A (es) Anticuerpos anti-globulomero ab, porciones de union a antigeno de estos, hibridomas correspondientes, acidos nucleicos, vectores, celulas huesped, metodos para producir dichos anticuerpos, composiciones que comprenden dichos anticuerpos
WO2005074656A3 (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2298872A3 (de) Polypeptide mit Lipase-Aktivität und diese kodierende Polynukleotide
DE60139542D1 (de) Methoden zur herstellung humaner monoklonaler antikörper
WO2005074647A3 (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
DK1831362T3 (da) Syreaktive svampeproteaser
SG10201408300PA (en) Processing of amplified dna fragments for sequencing
CU23791A3 (es) Método para la producción de proteínas y anticuerpos mejorados
EP1692255A4 (de) Isolierung von nukleinsäure aus mundepithelzellen
WO2006047469A8 (en) Polypeptides having lipase activity and polynucleotides encoding same
IS8035A (is) Nýir ljósóstöðugir verndarhópar til bættra aðferða við að framleiða fákirnafylkingar
NO20081470L (no) Polypeptider som har antimikrobeaktivitet og polynukleotider som koder for disse.
ATE407939T1 (de) 2ß-NITROBENZYL-MODIFIZIERTE RIBONUKLEOTIDE
ATE488591T1 (de) Neuer l-lysin-induzierbarer promotor
TW200510460A (en) Antimicrobial polypeptides
WO2010038145A3 (en) Kit for the optimisation of protein synthesis/secretion
DK1756273T3 (da) Signalpeptid til frembringelse af et polypeptid
ATE513041T1 (de) Ghrelin bindende nukleinsäuren
WO2008002548A3 (en) Novel human acidic mammalian chitinase and use thereof
DK1963514T3 (da) Fremgangsmåder til fototransferering af nukleinsyre til levende celler
DE602006014001D1 (de) Herstellung von 2-aminothiazol-5-carbonsäurederivaten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1763586

Country of ref document: EP