ATE380501T1 - Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten - Google Patents

Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten

Info

Publication number
ATE380501T1
ATE380501T1 AT99934149T AT99934149T ATE380501T1 AT E380501 T1 ATE380501 T1 AT E380501T1 AT 99934149 T AT99934149 T AT 99934149T AT 99934149 T AT99934149 T AT 99934149T AT E380501 T1 ATE380501 T1 AT E380501T1
Authority
AT
Austria
Prior art keywords
sensor
interface device
tissue interface
biological
fluid
Prior art date
Application number
AT99934149T
Other languages
English (en)
Inventor
Mark Samuels
Jonathan Eppstein
Michael Hatch
Original Assignee
Spectrx Inc
Altea Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrx Inc, Altea Therapeutics Corp filed Critical Spectrx Inc
Application granted granted Critical
Publication of ATE380501T1 publication Critical patent/ATE380501T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B2010/008Interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00137Details of operation mode
    • A61B2017/00154Details of operation mode pulsed
    • A61B2017/00172Pulse trains, bursts, intermittent continuous operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061Means for enhancing collection
    • A61B5/150099Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150969Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/155Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/157Devices characterised by integrated means for measuring characteristics of blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99934149T 1998-07-21 1999-07-20 Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten ATE380501T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9353498P 1998-07-21 1998-07-21
US26346499A 1999-03-05 1999-03-05
US14028599P 1999-06-18 1999-06-18
US14025299P 1999-06-18 1999-06-18

Publications (1)

Publication Number Publication Date
ATE380501T1 true ATE380501T1 (de) 2007-12-15

Family

ID=27492668

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99934149T ATE380501T1 (de) 1998-07-21 1999-07-20 Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten

Country Status (9)

Country Link
EP (1) EP1098594B1 (de)
JP (4) JP2004510453A (de)
AT (1) ATE380501T1 (de)
AU (1) AU5004299A (de)
BR (1) BR9912333A (de)
CA (1) CA2338203A1 (de)
DE (1) DE69937738D1 (de)
MX (1) MXPA01000698A (de)
WO (1) WO2000004832A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1189660T3 (da) 1999-06-08 2006-08-21 Altea Therapeutics Corp Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf
US6685699B1 (en) 1999-06-09 2004-02-03 Spectrx, Inc. Self-removing energy absorbing structure for thermal tissue ablation
JP2003501222A (ja) 1999-06-11 2003-01-14 アルテア テクノロジーズ,インコーポレイティド 効率的流体抽出、物質配送、およびその他の用途のための一体型整合装置、システム、および方法
AU5490600A (en) 1999-06-18 2001-01-09 Spectrx, Inc. System and method for monitoring glucose to assist in weight management and fitness training
US20030078499A1 (en) 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
CA2390893C (en) 1999-11-19 2010-10-05 Spectrx, Inc. Tissue interface device
AU2012201079B2 (en) * 2000-06-01 2013-03-28 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
AU2011205219B2 (en) * 2000-06-01 2011-11-24 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
CA2843053C (en) * 2000-06-01 2015-08-25 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
AU2014200664B2 (en) * 2000-06-01 2015-05-14 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
US7141034B2 (en) 2000-06-08 2006-11-28 Altea Therapeutics Corporation Transdermal drug delivery device, method of making same and method of using same
US7632522B2 (en) 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
EP1379127B1 (de) 2000-09-28 2013-04-17 Nanocyte Inc. Methoden, zusammensetzungen und vorrichtungen unter verwendung von stechzellen/kapseln zur abgabe eines therapeutischen mittels oder eines kosmetischen mittels in ein gewebe
GB0030929D0 (en) 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US7310543B2 (en) 2001-03-26 2007-12-18 Kumetrix, Inc. Silicon microprobe with integrated biosensor
US20020189947A1 (en) 2001-06-13 2002-12-19 Eksigent Technologies Llp Electroosmotic flow controller
US7465382B2 (en) 2001-06-13 2008-12-16 Eksigent Technologies Llc Precision flow control system
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
JP4260024B2 (ja) 2002-03-19 2009-04-30 バード ダブリン アイティーシー リミティッド 真空生検装置
AU2003218696A1 (en) 2002-03-19 2003-09-29 Bard Dublin Itc Limited Biopsy device and biopsy needle module that can be inserted into the biopsy device
EP1519755B1 (de) 2002-03-26 2008-05-07 Nanocyte Inc. Nesselzellen mit expression eines exogenen polynucleotids, das ein therapeutisches, diagnostisches oder kosmetisches mittel kodiert, und diese nesselzellen verwendende verfahren, zusammensetzungen und vorrichtungen oder daraus gewonnene kapseln zur abgabe des therapeutischen, diagnostischen oder kosmetischen mittels in ein gewebe
AU2003226605A1 (en) 2002-04-19 2003-11-03 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US7235164B2 (en) 2002-10-18 2007-06-26 Eksigent Technologies, Llc Electrokinetic pump having capacitive electrodes
US7517440B2 (en) 2002-07-17 2009-04-14 Eksigent Technologies Llc Electrokinetic delivery systems, devices and methods
DE10314240B4 (de) 2003-03-29 2025-05-28 Bard Dublin Itc Ltd. Druckerzeugungseinheit
WO2005084534A1 (en) * 2003-09-03 2005-09-15 Life Patch International, Inc. Personal diagnostic devices and related methods
US20050059166A1 (en) * 2003-09-11 2005-03-17 Robert Markes Sampling instrument
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US7559356B2 (en) 2004-04-19 2009-07-14 Eksident Technologies, Inc. Electrokinetic pump driven heat transfer system
US7521140B2 (en) 2004-04-19 2009-04-21 Eksigent Technologies, Llc Fuel cell system with electrokinetic pump
EP1768571B1 (de) 2004-07-09 2012-03-21 Bard Peripheral Vascular, Inc. Feuersystem für eine biopsievorrichtung
US7517321B2 (en) 2005-01-31 2009-04-14 C. R. Bard, Inc. Quick cycle biopsy system
WO2006111199A1 (de) * 2005-04-18 2006-10-26 Pantec Biosolutions Ag Microporator for porating a biological membran and integrated permeant administeirng system
US8834862B2 (en) 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
JP4955681B2 (ja) 2005-08-10 2012-06-20 シー・アール・バード・インコーポレーテッド 直線駆動装置を有する単一挿入複数サンプリング生検デバイス
US8267868B2 (en) 2005-08-10 2012-09-18 C. R. Bard, Inc. Single-insertion, multiple sample biopsy device with integrated markers
WO2007021904A2 (en) 2005-08-10 2007-02-22 C.R. Bard Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8152477B2 (en) 2005-11-23 2012-04-10 Eksigent Technologies, Llc Electrokinetic pump designs and drug delivery systems
EP2041574B1 (de) 2006-07-14 2016-11-16 The Regents of The University of California Krebsbiomarker und anwendungsverfahren dafür
US8251917B2 (en) 2006-08-21 2012-08-28 C. R. Bard, Inc. Self-contained handheld biopsy needle
ATE493074T1 (de) 2006-10-06 2011-01-15 Bard Peripheral Vascular Inc Gewebehandhabungssystem mit verringerter exposition der bedienungsperson
EP3714798A3 (de) 2006-10-24 2020-12-16 C. R. Bard, Inc. Biopsienadeln für grosse proben mit geringem aspektverhältnis
AU2008208009B2 (en) 2007-01-22 2013-08-15 Passport Technologies, Inc. Transdermal porator and patch system and method for using same
US7867592B2 (en) 2007-01-30 2011-01-11 Eksigent Technologies, Inc. Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces
WO2008154753A1 (en) * 2007-06-20 2008-12-24 Solianis Holding Ag Method for measuring the response of a tissue to an electromagnetic field
US9037229B2 (en) 2007-10-09 2015-05-19 Syneron Medical Ltd Magnetic patch coupling
US8281675B2 (en) 2007-10-17 2012-10-09 Syneron Medical Ltd Dissolution rate verification
KR101287351B1 (ko) 2007-12-05 2013-07-23 시네론 메디컬 리미티드 피부 치료장치용 캐리어
WO2009076134A1 (en) 2007-12-11 2009-06-18 Eksigent Technologies, Llc Electrokinetic pump with fixed stroke volume
US8241225B2 (en) 2007-12-20 2012-08-14 C. R. Bard, Inc. Biopsy device
US7854706B2 (en) 2007-12-27 2010-12-21 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
WO2010107424A1 (en) 2009-03-16 2010-09-23 C.R. Bard, Inc. Biopsy device having rotational cutting
ES2690737T3 (es) 2009-04-15 2018-11-22 C.R. Bard Inc. Gestión de fluido
US8206316B2 (en) 2009-06-12 2012-06-26 Devicor Medical Products, Inc. Tetherless biopsy device with reusable portion
EP2464294B1 (de) 2009-08-12 2019-10-02 C.R. Bard Inc. Biopsiegerät mit integriertem daumenradmechanismus zur manuellen rotation einer biopsiekanüle
US8485989B2 (en) 2009-09-01 2013-07-16 Bard Peripheral Vascular, Inc. Biopsy apparatus having a tissue sample retrieval mechanism
US8430824B2 (en) 2009-10-29 2013-04-30 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8283890B2 (en) 2009-09-25 2012-10-09 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
US8597206B2 (en) 2009-10-12 2013-12-03 Bard Peripheral Vascular, Inc. Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US20110105946A1 (en) * 2009-10-31 2011-05-05 Sorensen Peter L Biopsy system with infrared communications
US12571798B2 (en) 2010-04-27 2026-03-10 The Regents Of The University Of California Cancer biomarkers and methods of use thereof
WO2012048150A1 (en) * 2010-10-06 2012-04-12 Profusa, Inc. Tissue-integrating sensors
JP2014519570A (ja) 2011-05-05 2014-08-14 エクシジェント テクノロジーズ, エルエルシー 動電学的送出システム用のゲル結合部
US10004434B1 (en) 2013-03-15 2018-06-26 Georgetown University Microfluidic systems for electrochemical transdermal analyte sensing using a capillary-located electrode
ES2875575T3 (es) 2013-03-20 2021-11-10 Bard Peripheral Vascular Inc Dispositivo de biopsia
EP3549533B1 (de) 2013-11-05 2020-12-30 C.R. Bard, Inc. Biopsievorrichtung mit integriertem vakuum
EP3128913B1 (de) * 2014-04-10 2019-05-08 Dexcom, Inc. Bestimmung des dringlichen index eines benutzers mit einem physiologischen zustand
JP6636136B2 (ja) 2015-05-01 2020-01-29 シー・アール・バード・インコーポレーテッドC R Bard Incorporated 生検装置
US11219390B2 (en) 2015-08-03 2022-01-11 Georgetown University Apparatus and method for delivery of antimicrobial during a transdermal sampling and delivery process
HUE069886T2 (hu) * 2017-02-14 2025-04-28 Hoffmann La Roche Számítógéppel megvalósított eljárás és hordozható eszköz testfolyadék glükózszintjére vonatkozó glükózmonitorozási adatok elemzésére, valamint számítógéppel olvasható tartós adathordozó
US11844500B2 (en) 2017-05-19 2023-12-19 Merit Medical Systems, Inc. Semi-automatic biopsy needle device and methods of use
EP3624697B1 (de) 2017-05-19 2024-02-14 Merit Medical Systems, Inc. Biopsienadelvorrichtungen und verfahren zur verwendung
WO2018213580A1 (en) 2017-05-19 2018-11-22 Merit Medical Systems, Inc. Rotating biopsy needle
WO2020102277A1 (en) * 2018-11-13 2020-05-22 University Of Cincinnati Quality assurance of collected interstitial fluid samples
GB2584143B (en) * 2019-05-23 2022-03-02 Ip2Ipo Innovations Ltd A sensor formed in a drawable fibre
US12295556B2 (en) 2019-09-27 2025-05-13 Merit Medical Systems, Inc. Rotation biopsy system and handle
US12150627B2 (en) 2019-12-11 2024-11-26 Merit Medical Systems, Inc. Bone biopsy device and related methods
US20230347050A1 (en) * 2022-04-30 2023-11-02 Brian Haney Synthetic thyroid methods and apparatus

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992158A (en) 1973-08-16 1976-11-16 Eastman Kodak Company Integral analytical element
JPS50123493A (de) 1974-03-15 1975-09-27
US4050898A (en) 1976-04-26 1977-09-27 Eastman Kodak Company Integral analytical element
US4053381A (en) 1976-05-19 1977-10-11 Eastman Kodak Company Device for determining ionic activity of components of liquid drops
US4839296A (en) 1985-10-18 1989-06-13 Chem-Elec, Inc. Blood plasma test method
US4774192A (en) 1987-01-28 1988-09-27 Technimed Corporation A dry reagent delivery system with membrane having porosity gradient
WO1989006989A1 (en) * 1988-01-29 1989-08-10 The Regents Of The University Of California Iontophoretic non-invasive sampling or delivery device
US5161532A (en) * 1990-04-19 1992-11-10 Teknekron Sensor Development Corporation Integral interstitial fluid sensor
JP2852457B2 (ja) * 1990-06-29 1999-02-03 ミネベア株式会社 内燃機関用コンロッドボルト
JP2529186Y2 (ja) * 1990-09-28 1997-03-19 日本電気株式会社 吸引装置
US5271895A (en) 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
JP2751978B2 (ja) * 1992-04-28 1998-05-18 技術研究組合医療福祉機器研究所 無侵襲連続血糖値測定装置
JPH0824680B2 (ja) * 1992-10-26 1996-03-13 日本電気株式会社 吸引浸出液採取装置
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
DE69519023T2 (de) * 1994-06-24 2001-06-13 Cygnus, Inc. Einrichtung zur iontophoretischen probennahme
JP2665485B2 (ja) * 1995-06-09 1997-10-22 技術研究組合医療福祉機器研究所 経皮的連続血糖値測定システム
JP2692650B2 (ja) * 1995-06-12 1997-12-17 日本電気株式会社 浸出液吸引装置
JP2713255B2 (ja) * 1995-08-11 1998-02-16 日本電気株式会社 浸出液吸引装置
ES2536459T3 (es) * 1995-08-29 2015-05-25 Nitto Denko Corporation Microporación de piel humana para administración de fármacos y aplicaciones de supervisión
US6009343A (en) * 1996-02-23 1999-12-28 Abbott Laboratories Enhanced transdermal transport of fluid using vacuum
DE19758959B8 (de) * 1996-05-17 2013-08-01 Roche Diagnostics Operations Inc. (N.D.Ges.D.Staates Delaware) Vorrichtung zum Ausdrücken von Körperflüssigkeiten aus einem Einstich
CA2253549C (en) * 1996-06-18 2005-10-25 Alza Corporation Device for enhancing transdermal agent delivery or sampling

Also Published As

Publication number Publication date
AU5004299A (en) 2000-02-14
EP1098594B1 (de) 2007-12-12
BR9912333A (pt) 2001-04-17
JP2013009992A (ja) 2013-01-17
JP5639132B2 (ja) 2014-12-10
MXPA01000698A (es) 2002-04-08
EP1098594A1 (de) 2001-05-16
CA2338203A1 (en) 2000-02-03
JP2004510453A (ja) 2004-04-08
JP2010194343A (ja) 2010-09-09
JP2012020158A (ja) 2012-02-02
DE69937738D1 (de) 2008-01-24
WO2000004832A1 (en) 2000-02-03

Similar Documents

Publication Publication Date Title
DE69937738D1 (de) Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten
ATE318103T1 (de) Vorrichtung zur kontinuierlichen entnahme und analyse von flüssigkeiten
SE9604320D0 (sv) Medical device
ATE408373T1 (de) Messfühlereinheit und verfahren zur messung eines blutrelevanten parameters und system mit einer solchen messfühlereinheit
CA2332112A1 (en) Monitoring of physiological analytes
ATE361024T1 (de) Vorrichtung und verfahren zur bestimmung des analytpegels
ATE355865T1 (de) Messvorrichtung und -verfahren zur bestimmung von parametern medizinischer flüssigkeiten
ATE549616T1 (de) Verfahren zur oel-in-wasser messung
SE9702658D0 (sv) Regeneration of biosensors
DE69016428D1 (de) Vorrichtung und verfahren zur bestimmung eines bestandteiles in einer flüssigkeitsprobe.
ATE258028T1 (de) Signalverarbeitung zur messung von physiologischen analyten
DE60037547D1 (de) Verfahren und Vorrichtung zur Blutbehandlung mit Sensoren zur Erkennung von Kontaminationen
ATE406835T1 (de) Verfahren und vorrichtung zur überwachung der analytkonzentration durch optischen nachweis
DE602004031373D1 (de) Vorrichtung und verfahren zur überwachung von körperflüssigkeit und elektrolytenstörungen
DE60027720D1 (de) Vorrichtung zur mikroporation eines biologischen gewebes mittels einer filmgewebe schnittstellenvorrichtung und verfahren
EP1484010A3 (de) Laserblutflussmessgerät und System zur Überwachung von Biodaten
ATE427067T1 (de) Verfahren zur detektierung von temperaturanderungen
DE69832418D1 (de) Differenzdrucksystem zur überwachung eines filterbettes
ATA114789A (de) Verfahren und vorrichtung zur feststellung biologischer aktivitaeten in einer probe
ATE185197T1 (de) Vorrichtung zur analyse einer flüssigkeit
ATE401035T1 (de) Verfahren und vorrichtung zur messung des dynamischen verhaltens des auges
SE9500020L (sv) Kemiska sensorer baserade på utbytbara igekänningskomponenter
ATE360203T1 (de) Verfahren und vorrichtung zur bestimmung des zustandes einer messsonde
FR2830325B1 (fr) Dispositif de mesure des caracteristiques d'absorption lumineuse d'un echantillon de tissu biologique, procede de mesure associe, et applications dans le domaine de l'analyse vegetale et le domaine medical
DK185891A (da) Apparat til detektion af mikroorganismer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties