ATE380501T1 - Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten - Google Patents

Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten

Info

Publication number
ATE380501T1
ATE380501T1 AT99934149T AT99934149T ATE380501T1 AT E380501 T1 ATE380501 T1 AT E380501T1 AT 99934149 T AT99934149 T AT 99934149T AT 99934149 T AT99934149 T AT 99934149T AT E380501 T1 ATE380501 T1 AT E380501T1
Authority
AT
Austria
Prior art keywords
sensor
interface device
tissue interface
biological
fluid
Prior art date
Application number
AT99934149T
Other languages
English (en)
Inventor
Mark Samuels
Jonathan Eppstein
Michael Hatch
Original Assignee
Spectrx Inc
Altea Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrx Inc, Altea Therapeutics Corp filed Critical Spectrx Inc
Application granted granted Critical
Publication of ATE380501T1 publication Critical patent/ATE380501T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00137—Details of operation mode
    • A61B2017/00154—Details of operation mode pulsed
    • A61B2017/00172—Pulse trains, bursts, intermittent continuous operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/155—Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99934149T 1998-07-21 1999-07-20 Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten ATE380501T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9353498P 1998-07-21 1998-07-21
US26346499A 1999-03-05 1999-03-05
US14028599P 1999-06-18 1999-06-18
US14025299P 1999-06-18 1999-06-18

Publications (1)

Publication Number Publication Date
ATE380501T1 true ATE380501T1 (de) 2007-12-15

Family

ID=27492668

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99934149T ATE380501T1 (de) 1998-07-21 1999-07-20 Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten

Country Status (9)

Country Link
EP (1) EP1098594B1 (de)
JP (4) JP2004510453A (de)
AT (1) ATE380501T1 (de)
AU (1) AU5004299A (de)
BR (1) BR9912333A (de)
CA (1) CA2338203A1 (de)
DE (1) DE69937738D1 (de)
MX (1) MXPA01000698A (de)
WO (1) WO2000004832A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4412874B2 (ja) 1999-06-08 2010-02-10 アルテア セラピューティクス コーポレイション 薄膜組織インターフェイスデバイスを使用する生物学的膜のミクロポレーションのための装置、およびそのための方法
US6685699B1 (en) 1999-06-09 2004-02-03 Spectrx, Inc. Self-removing energy absorbing structure for thermal tissue ablation
AU5482000A (en) 1999-06-11 2001-01-02 Altea Therapeutics Corporation Integrated alignment devices, systems, and methods for efficient fluid extraction, substance delivery and other applications
WO2000078208A1 (en) 1999-06-18 2000-12-28 Spectrx, Inc. System and method for monitoring glucose to assist in weight management and fitness training
US20030078499A1 (en) 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
AU1778601A (en) 1999-11-19 2001-05-30 Altea Therapeutics Corporation Tissue interface device
AU2012201079B2 (en) * 2000-06-01 2013-03-28 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
AU2014200664B2 (en) * 2000-06-01 2015-05-14 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
AU2011205219B2 (en) * 2000-06-01 2011-11-24 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
US6887202B2 (en) * 2000-06-01 2005-05-03 Science Applications International Corporation Systems and methods for monitoring health and delivering drugs transdermally
US7632522B2 (en) 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
AU2001295850A1 (en) 2000-09-28 2002-04-08 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
GB0030929D0 (en) 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US7310543B2 (en) 2001-03-26 2007-12-18 Kumetrix, Inc. Silicon microprobe with integrated biosensor
US7465382B2 (en) 2001-06-13 2008-12-16 Eksigent Technologies Llc Precision flow control system
US20020189947A1 (en) 2001-06-13 2002-12-19 Eksigent Technologies Llp Electroosmotic flow controller
CA2478822C (en) 2002-03-11 2016-07-12 Passport Technologies, Inc. Transdermal drug delivery patch system, method of making same and method of using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
CA2479349C (en) 2002-03-19 2012-07-03 Bard Dublin Itc Limited Biopsy device and biopsy needle module that can be inserted into the biopsy device
DE50301103D1 (de) 2002-03-19 2005-10-06 Bard Dublin Itc Ltd Vakuum-biopsievorrichtung
EP1519755B1 (de) 2002-03-26 2008-05-07 Nanocyte Inc. Nesselzellen mit expression eines exogenen polynucleotids, das ein therapeutisches, diagnostisches oder kosmetisches mittel kodiert, und diese nesselzellen verwendende verfahren, zusammensetzungen und vorrichtungen oder daraus gewonnene kapseln zur abgabe des therapeutischen, diagnostischen oder kosmetischen mittels in ein gewebe
WO2003089043A2 (en) 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US7517440B2 (en) 2002-07-17 2009-04-14 Eksigent Technologies Llc Electrokinetic delivery systems, devices and methods
US7235164B2 (en) 2002-10-18 2007-06-26 Eksigent Technologies, Llc Electrokinetic pump having capacitive electrodes
DE10314240B4 (de) 2003-03-29 2025-05-28 Bard Dublin Itc Ltd. Druckerzeugungseinheit
JP2007503958A (ja) * 2003-09-03 2007-03-01 ライフパッチ インターナショナル,インコーポレイテッド 個人診断装置と関連手法
US20050059166A1 (en) * 2003-09-11 2005-03-17 Robert Markes Sampling instrument
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US7559356B2 (en) 2004-04-19 2009-07-14 Eksident Technologies, Inc. Electrokinetic pump driven heat transfer system
US7521140B2 (en) 2004-04-19 2009-04-21 Eksigent Technologies, Llc Fuel cell system with electrokinetic pump
US8052615B2 (en) 2004-07-09 2011-11-08 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US7517321B2 (en) 2005-01-31 2009-04-14 C. R. Bard, Inc. Quick cycle biopsy system
EP1874212A1 (de) * 2005-04-18 2008-01-09 Pantec Biosolutions AG Mikroporator zur poration einer biologischen membran und integriertes durchdringendes verabreichungssystem
US8834862B2 (en) 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
CA2616714C (en) 2005-08-10 2017-01-24 Jon Taylor Single-insertion, multiple sample biopsy device with integrated markers
CA2616823C (en) 2005-08-10 2014-06-03 C.R. Bard Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
EP1921998B8 (de) 2005-08-10 2021-07-07 C.R.Bard, Inc. Biopsievorrichtung mit linearantrieb für mehrfache probennahme mit einzeleinführung
EP1957794B1 (de) 2005-11-23 2014-07-02 Eksigent Technologies, LLC Elektrokinetische pumpenausführungen und arzneimittelabgabesysteme
CA2657576C (en) 2006-07-14 2023-10-31 The Regents Of The University Of California Cancer biomarkers and methods of use thereof
WO2008024684A2 (en) 2006-08-21 2008-02-28 C.R. Bard, Inc. Self-contained handheld biopsy needle
SI2086418T1 (sl) 2006-10-06 2011-05-31 Bard Peripheral Vascular Inc Sistem za obdelavo tkiva z zmanjšano izpostavljenostjo operaterja
EP3714798A3 (de) 2006-10-24 2020-12-16 C. R. Bard, Inc. Biopsienadeln für grosse proben mit geringem aspektverhältnis
CA2676255C (en) 2007-01-22 2016-06-07 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US7867592B2 (en) 2007-01-30 2011-01-11 Eksigent Technologies, Inc. Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces
US20100240977A1 (en) * 2007-06-20 2010-09-23 Andreas Caduff Method for measuring the response of a tissue to an electromagnetic field
US9037229B2 (en) 2007-10-09 2015-05-19 Syneron Medical Ltd Magnetic patch coupling
CA2696227A1 (en) 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
WO2009072108A2 (en) 2007-12-05 2009-06-11 Syneron Medical Ltd. A disposable electromagnetic energy applicator and method of using it
US8251672B2 (en) 2007-12-11 2012-08-28 Eksigent Technologies, Llc Electrokinetic pump with fixed stroke volume
US8241225B2 (en) 2007-12-20 2012-08-14 C. R. Bard, Inc. Biopsy device
US7854706B2 (en) 2007-12-27 2010-12-21 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
EP2408378A4 (de) 2009-03-16 2013-10-09 Bard Inc C R Biopsievorrichtung mit rotationsschneidevorrichtung
CA2965976C (en) 2009-04-15 2019-05-07 C.R. Bard, Inc. Biopsy apparatus having integrated fluid management
US8206316B2 (en) 2009-06-12 2012-06-26 Devicor Medical Products, Inc. Tetherless biopsy device with reusable portion
WO2011019343A1 (en) 2009-08-12 2011-02-17 C.R. Bard, Inc. Biopsy appaparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US8485989B2 (en) 2009-09-01 2013-07-16 Bard Peripheral Vascular, Inc. Biopsy apparatus having a tissue sample retrieval mechanism
US8283890B2 (en) 2009-09-25 2012-10-09 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
US8430824B2 (en) 2009-10-29 2013-04-30 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8597206B2 (en) 2009-10-12 2013-12-03 Bard Peripheral Vascular, Inc. Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US20110105946A1 (en) * 2009-10-31 2011-05-05 Sorensen Peter L Biopsy system with infrared communications
WO2011139721A1 (en) 2010-04-27 2011-11-10 The Regents Of The University Of California Cancer biomarkers and methods of use thereof
JP5827999B2 (ja) * 2010-10-06 2015-12-02 プロフューザ,インコーポレイティド 組織集積センサー
EP2704759A4 (de) 2011-05-05 2015-06-03 Eksigent Technologies Llc Gelkupplung für elektrokinetische abgabesysteme
US10004434B1 (en) 2013-03-15 2018-06-26 Georgetown University Microfluidic systems for electrochemical transdermal analyte sensing using a capillary-located electrode
ES2875575T3 (es) 2013-03-20 2021-11-10 Bard Peripheral Vascular Inc Dispositivo de biopsia
US10456120B2 (en) 2013-11-05 2019-10-29 C. R. Bard, Inc. Biopsy device having integrated vacuum
US20150289821A1 (en) * 2014-04-10 2015-10-15 Dexcom, Inc. Glycemic urgency assessment and alerts interface
AU2015393933B2 (en) 2015-05-01 2020-03-19 C. R. Bard, Inc. Biopsy device
WO2017023931A1 (en) 2015-08-03 2017-02-09 Georgetown University Apparatus and method for delivery of antimicrobial during a transdermal sampling and delivery process
ES3007562T3 (en) * 2017-02-14 2025-03-20 Hoffmann La Roche A computer-implemented method and a portable device for analyzing glucose monitoring data indicative of a glucose level in a bodily fluid, and a non-transitory computer readable medium
EP4378396A3 (de) 2017-05-19 2024-08-28 Merit Medical Systems, Inc. Biopsienadelvorrichtungen und verfahren zur verwendung
WO2018213324A1 (en) 2017-05-19 2018-11-22 Merit Medical Systems, Inc. Semi-automatic biopsy needle device and methods of use
WO2018213580A1 (en) 2017-05-19 2018-11-22 Merit Medical Systems, Inc. Rotating biopsy needle
WO2020102277A1 (en) * 2018-11-13 2020-05-22 University Of Cincinnati Quality assurance of collected interstitial fluid samples
GB2584143B (en) * 2019-05-23 2022-03-02 Ip2Ipo Innovations Ltd A sensor formed in a drawable fibre
US12295556B2 (en) 2019-09-27 2025-05-13 Merit Medical Systems, Inc. Rotation biopsy system and handle
US12150627B2 (en) 2019-12-11 2024-11-26 Merit Medical Systems, Inc. Bone biopsy device and related methods
US20230347050A1 (en) * 2022-04-30 2023-11-02 Brian Haney Synthetic thyroid methods and apparatus

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992158A (en) 1973-08-16 1976-11-16 Eastman Kodak Company Integral analytical element
JPS50123493A (de) 1974-03-15 1975-09-27
US4050898A (en) 1976-04-26 1977-09-27 Eastman Kodak Company Integral analytical element
US4053381A (en) 1976-05-19 1977-10-11 Eastman Kodak Company Device for determining ionic activity of components of liquid drops
US4839296A (en) 1985-10-18 1989-06-13 Chem-Elec, Inc. Blood plasma test method
US4774192A (en) 1987-01-28 1988-09-27 Technimed Corporation A dry reagent delivery system with membrane having porosity gradient
JP2907342B2 (ja) * 1988-01-29 1999-06-21 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア イオン滲透非侵襲的サンプリングまたは送出装置
US5161532A (en) * 1990-04-19 1992-11-10 Teknekron Sensor Development Corporation Integral interstitial fluid sensor
JP2852457B2 (ja) * 1990-06-29 1999-02-03 ミネベア株式会社 内燃機関用コンロッドボルト
JP2529186Y2 (ja) * 1990-09-28 1997-03-19 日本電気株式会社 吸引装置
US5271895A (en) 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
JP2751978B2 (ja) * 1992-04-28 1998-05-18 技術研究組合医療福祉機器研究所 無侵襲連続血糖値測定装置
JPH0824680B2 (ja) * 1992-10-26 1996-03-13 日本電気株式会社 吸引浸出液採取装置
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
DK0766578T3 (da) * 1994-06-24 2000-10-23 Cygnus Therapeutic Systems Iontophoretisk prøvetagningsindretning
JP2665485B2 (ja) * 1995-06-09 1997-10-22 技術研究組合医療福祉機器研究所 経皮的連続血糖値測定システム
JP2692650B2 (ja) * 1995-06-12 1997-12-17 日本電気株式会社 浸出液吸引装置
JP2713255B2 (ja) * 1995-08-11 1998-02-16 日本電気株式会社 浸出液吸引装置
AU707065B2 (en) * 1995-08-29 1999-07-01 Nitto Denko Corporation Microporation of human skin for drug delivery and monitoring applications
US6009343A (en) * 1996-02-23 1999-12-28 Abbott Laboratories Enhanced transdermal transport of fluid using vacuum
ATE381904T1 (de) * 1996-05-17 2008-01-15 Roche Diagnostics Operations Körperflüssigkeitsentnahmevorrichtung
US7184826B2 (en) * 1996-06-18 2007-02-27 Alza Corporation Device and method for enhancing transdermal flux of agents being delivered or sampled

Also Published As

Publication number Publication date
BR9912333A (pt) 2001-04-17
EP1098594B1 (de) 2007-12-12
JP5639132B2 (ja) 2014-12-10
WO2000004832A1 (en) 2000-02-03
JP2013009992A (ja) 2013-01-17
DE69937738D1 (de) 2008-01-24
MXPA01000698A (es) 2002-04-08
AU5004299A (en) 2000-02-14
JP2012020158A (ja) 2012-02-02
JP2010194343A (ja) 2010-09-09
CA2338203A1 (en) 2000-02-03
JP2004510453A (ja) 2004-04-08
EP1098594A1 (de) 2001-05-16

Similar Documents

Publication Publication Date Title
DE69937738D1 (de) Verfahren und vorrichtung zur kontinuierlichen überwachung eines analyten
ATE318103T1 (de) Vorrichtung zur kontinuierlichen entnahme und analyse von flüssigkeiten
DK1077634T3 (da) Monitorering af fysiologiske analytter
DE60323633D1 (de) Messfühlereinheit und verfahren zur messung eines blutrelevanten parameters und system mit einer solchen messfühlereinheit
SE9604320D0 (sv) Medical device
ATE361024T1 (de) Vorrichtung und verfahren zur bestimmung des analytpegels
DE60306711D1 (de) Verfahren und Vorrichtung zur Sammlung von physiologischen Proben
ATE355865T1 (de) Messvorrichtung und -verfahren zur bestimmung von parametern medizinischer flüssigkeiten
ATE549616T1 (de) Verfahren zur oel-in-wasser messung
SE9702658D0 (sv) Regeneration of biosensors
DE69016428D1 (de) Vorrichtung und verfahren zur bestimmung eines bestandteiles in einer flüssigkeitsprobe.
ATE518119T1 (de) Vorrichtung zur bestimmung des füllstands eines mediums
DE69914319D1 (de) Signalverarbeitung zur messung von physiologischen analyten
DE60037547D1 (de) Verfahren und Vorrichtung zur Blutbehandlung mit Sensoren zur Erkennung von Kontaminationen
ATE406835T1 (de) Verfahren und vorrichtung zur überwachung der analytkonzentration durch optischen nachweis
EP1484010A3 (de) Laserblutflussmessgerät und System zur Überwachung von Biodaten
ATE427067T1 (de) Verfahren zur detektierung von temperaturanderungen
ATE309852T1 (de) Differenzdrucksystem zur überwachung eines filterbettes
ATA114789A (de) Verfahren und vorrichtung zur feststellung biologischer aktivitaeten in einer probe
DE69420962D1 (de) Vorrichtung zur analyse einer flüssigkeit
ATE401035T1 (de) Verfahren und vorrichtung zur messung des dynamischen verhaltens des auges
EP0895747A3 (de) Druckregeleinrichtung und Verfahren zur Andruckregelung für einen lebenden Körper während biologischer Datenmessung
ATE551428T1 (de) Polymermembranen zur verwendung in elektrochemischen sensoren
SE9500020D0 (sv) Kemiska sensorer baserade på utbytbara igekänningskomponenter
ATE360203T1 (de) Verfahren und vorrichtung zur bestimmung des zustandes einer messsonde

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties