ATE380834T1 - Polymermikroemulsionen - Google Patents

Polymermikroemulsionen

Info

Publication number: ATE380834T1
Authority: AT; Austria
Prior art keywords: polymer microemulsions; microemulsions; polymer
Prior art date: 2002-05-03

Application number

AT03717321T

Other languages

English (en)

Inventor

Albertina Maria Eduarda Arien

Marcus Eli Brewster

Aruna Nathan

Joel Rosenblatt

Louisa Myriam Ould-Ouali

Veronique Preat

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-03

Filing date

2003-04-24

Publication date

2007-12-15

2003-04-24 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2007-12-15 Application granted granted Critical

2007-12-15 Publication of ATE380834T1 publication Critical patent/ATE380834T1/de

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/46—Polyesters chemically modified by esterification
- C08G63/48—Polyesters chemically modified by esterification by unsaturated higher fatty oils or their acids; by resin acids
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/18—Block or graft polymers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/18—Block or graft polymers
- C08G64/183—Block or graft polymers containing polyether sequences
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
- C08G2261/10—Definition of the polymer structure
- C08G2261/12—Copolymers
- C08G2261/126—Copolymers block
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/05—Polymer mixtures characterised by other features containing polymer components which can react with one another
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Polymers & Plastics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Inorganic Chemistry (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Oil, Petroleum & Natural Gas (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Preparation (AREA)
Colloid Chemistry (AREA)
Polymerisation Methods In General (AREA)
Polyesters Or Polycarbonates (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polyethers (AREA)
Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Paper (AREA)
Compositions Of Macromolecular Compounds (AREA)
Centrifugal Separators (AREA)

AT03717321T 2002-05-03 2003-04-24 Polymermikroemulsionen ATE380834T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US37790102P	2002-05-03	2002-05-03

Publications (1)

Publication Number	Publication Date
ATE380834T1 true ATE380834T1 (de)	2007-12-15

Family

ID=29401581

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03717321T ATE380834T1 (de)	2002-05-03	2003-04-24	Polymermikroemulsionen

Country Status (22)

Country	Link
US (3)	US20060034797A1 (de)
EP (1)	EP1504047B1 (de)
JP (1)	JP4300184B2 (de)
KR (1)	KR20040111466A (de)
CN (1)	CN1290893C (de)
AR (1)	AR039522A1 (de)
AT (1)	ATE380834T1 (de)
AU (1)	AU2003222310B2 (de)
BR (1)	BR0309688A (de)
CA (1)	CA2483282C (de)
DE (1)	DE60318035T2 (de)
EA (1)	EA008244B1 (de)
ES (1)	ES2298510T3 (de)
IL (1)	IL164977A (de)
MX (1)	MXPA04010778A (de)
MY (1)	MY139066A (de)
NO (1)	NO20045283L (de)
NZ (1)	NZ536294A (de)
PL (1)	PL220850B1 (de)
TW (1)	TWI310388B (de)
WO (1)	WO2003093344A1 (de)
ZA (1)	ZA200408854B (de)

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US7638522B2 (en) *	2001-08-13	2009-12-29	Janssen Pharmaceutica N.V.	Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
US8101629B2 (en) *	2001-08-13	2012-01-24	Janssen Pharmaceutica N.V.	Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
JO3429B1 (ar)	2001-08-13	2019-10-20	Janssen Pharmaceutica Nv	مشتقات برميدينات مثبطة فيروس الايدز
US7399856B2 (en) *	2002-08-09	2008-07-15	Janssen Pharmaceutica N.V.	Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-2pyrimidinyl]amino]benzonitrile
ATE388758T1 (de) *	2002-10-21	2008-03-15	Oreal	Verfahren zum auflösen lipophiler verbindungen, und kosmetische zusammensetzung.
US7968115B2 (en) *	2004-03-05	2011-06-28	Board Of Regents, The University Of Texas System	Liposomal curcumin for treatment of cancer
US8784881B2 (en)	2004-03-05	2014-07-22	Board Of Regents, The University Of Texas System	Liposomal curcumin for treatment of diseases
JP4929567B2 (ja) *	2004-08-05	2012-05-09	コニカミノルタエムジー株式会社	ポリマーミセル含有製剤の製造方法
AU2005289100B2 (en) *	2004-09-29	2011-11-03	Bayer Healthcare Llc	Thermodynamically stable form of bay 43-9006 tosylate
US7888380B2 (en) *	2004-10-08	2011-02-15	Janssen Pharmaceutica, N.V.	1,2,4-Triazolylaminoaryl (heteroaryl) sulfonamide derivatives
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JP4892264B2 (ja) *	2006-03-30	2012-03-07	高田製薬株式会社	リスペリドン水性液剤
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AR062927A1 (es) *	2006-10-11	2008-12-17	Bayer Healthcare Ag	4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
WO2008055629A1 (en) *	2006-11-09	2008-05-15	Bayer Schering Pharma Aktiengesellschaft	Polymorph iii of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide
JP2010509382A (ja) *	2006-11-14	2010-03-25	バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト	４−［４−（｛［４−クロロ−３−（トリフルオロメチル）フェニル］カルバモイル｝アミノ）−３−フルオロフェノキシ］−ｎ−メチルピリジン−２−カルボキサミドの多形ｉｉ
CA2710051C (en)	2006-12-29	2017-05-16	Rigel Pharmaceuticals, Inc.	Substituted triazoles useful as axl inhibitors
ES2406930T3 (es)	2006-12-29	2013-06-10	Rigel Pharmaceuticals, Inc.	Triazoles sustituidos con arilo bicíclico y heteroarilo bicíclico útiles como inhibidores de AXL
CA2710230C (en)	2006-12-29	2016-02-23	Rigel Pharmaceuticals, Inc.	Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
CN101622248B (zh)	2006-12-29	2013-04-17	里格尔制药公司	用作axl抑制剂的n3-杂芳基取代的三唑和n5-杂芳基取代的三唑
RS53281B (sr)	2006-12-29	2014-08-29	Rigel Pharmaceuticals Inc.	Policiklični heteroaril supstituisani triazoli koji su korisni kao axl inhibitori
NZ582332A (en) *	2007-05-25	2012-02-24	Univ British Columbia	Formulations for the oral administration of amphotericin b and related methods
FR2919296A1 (fr) *	2007-07-25	2009-01-30	Rhodia Operations Sas	Ouverture de cycles epoxy par des carbenes.
CA2704052C (en)	2007-10-26	2015-04-21	Rigel Pharmaceuticals, Inc.	Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as axl inhibitors
CA2730251C (en)	2008-07-09	2016-08-09	Rigel Pharmaceuticals, Inc.	Bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
CA2730231C (en)	2008-07-09	2016-10-18	Rigel Pharmaceuticals, Inc.	Polycyclic heteroaryl substituted triazoles useful as axl inhibitors
MY160360A (en)	2008-12-24	2017-02-28	Janssen Sciences Ireland Uc	Implantable devices for treating hiv
EP2201935B1 (de) *	2008-12-26	2020-07-08	Samyang Biopharmaceuticals Corporation	Polymere Mizellenzusammensetzung, die ein schlecht lösliches Arzneimittel enthält, und zugehöriges Herstellungsverfahren
CN101444510B (zh) *	2008-12-31	2011-03-09	南京卡文迪许生物工程技术有限公司	含有伏立康唑的药物制剂及其制备方法
BRPI1007046B1 (pt)	2009-01-16	2019-07-16	Rigel Pharmaceuticals, Inc.	Inibidores axl para uso em terapia de combinação para evitar, tratar ou controlar o câncer metastático.
CN101531756B (zh) *	2009-04-16	2011-06-15	山东大学	一种水溶性聚乙二醇/聚乳酸多嵌段聚碳酸酯的制备方法
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WO2011050457A1 (en)	2009-10-26	2011-05-05	The University Of British Columbia	Stabilized formulation for oral administration of therapeutic agents and related methods
MY165655A (en) *	2010-12-29	2018-04-18	Medincell	Biodegradable drug delivery compositions
EP2634179A1 (de) *	2012-02-28	2013-09-04	Sanofi	Funktionale PLA-PEG-Copolymere, Nanopartikel, Herstellung und Verwendung zur gezielten Arzneimittelabgabe und Abbildung
ITTO20130431A1 (it) *	2013-05-28	2014-11-29	Fond Istituto Italiano Di Tecnologia	Copolimero e nanoparticelle da esso ottenute per la veicolazione di un farmaco
WO2015034678A2 (en)	2013-09-06	2015-03-12	Aptalis Pharmatech, Inc.	Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
CN104523592B (zh) *	2015-01-26	2017-03-15	湖北工业大学	甲泼尼龙醋酸酯注射用自微乳制剂及其制备方法
AU2016355236C1 (en)	2015-11-16	2022-09-22	Medincell	A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
TWI777515B (zh)	2016-08-18	2022-09-11	美商愛戴爾製藥股份有限公司	治療嗜伊紅性食道炎之方法
US12691128B2 (en)	2019-10-01	2026-07-28	Ellodi Pharmaceuticals, L.P.	Methods of treating eosinophilic esophagitis and reducing candidiasis
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2003
- 2003-04-24 MX MXPA04010778A patent/MXPA04010778A/es active IP Right Grant
- 2003-04-24 US US10/522,456 patent/US20060034797A1/en not_active Abandoned
- 2003-04-24 EA EA200401465A patent/EA008244B1/ru not_active IP Right Cessation
- 2003-04-24 CA CA2483282A patent/CA2483282C/en not_active Expired - Fee Related
- 2003-04-24 DE DE60318035T patent/DE60318035T2/de not_active Expired - Lifetime
- 2003-04-24 AU AU2003222310A patent/AU2003222310B2/en not_active Ceased
- 2003-04-24 ES ES03717321T patent/ES2298510T3/es not_active Expired - Lifetime
- 2003-04-24 EP EP03717321A patent/EP1504047B1/de not_active Expired - Lifetime
- 2003-04-24 JP JP2004501483A patent/JP4300184B2/ja not_active Expired - Fee Related
- 2003-04-24 BR BR0309688-2A patent/BR0309688A/pt not_active IP Right Cessation
- 2003-04-24 KR KR10-2004-7015633A patent/KR20040111466A/ko not_active Ceased
- 2003-04-24 AT AT03717321T patent/ATE380834T1/de not_active IP Right Cessation
- 2003-04-24 CN CNB038095793A patent/CN1290893C/zh not_active Expired - Fee Related
- 2003-04-24 PL PL371934A patent/PL220850B1/pl unknown
- 2003-04-24 NZ NZ536294A patent/NZ536294A/en unknown
- 2003-04-24 WO PCT/EP2003/004368 patent/WO2003093344A1/en not_active Ceased
- 2003-04-30 MY MYPI20031645A patent/MY139066A/en unknown
- 2003-05-02 TW TW092112064A patent/TWI310388B/zh active
- 2003-05-02 AR ARP030101540A patent/AR039522A1/es unknown
2004
- 2004-11-02 ZA ZA200408854A patent/ZA200408854B/en unknown
- 2004-11-02 IL IL164977A patent/IL164977A/en active IP Right Grant
- 2004-12-02 NO NO20045283A patent/NO20045283L/no not_active Application Discontinuation
2011
- 2011-01-06 US US12/985,608 patent/US20110112115A1/en not_active Abandoned
2014
- 2014-12-01 US US14/557,058 patent/US20150086504A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2483282C (en)	2012-05-29
WO2003093344A1 (en)	2003-11-13
US20060034797A1 (en)	2006-02-16
PL220850B1 (pl)	2016-01-29
JP4300184B2 (ja)	2009-07-22
EP1504047B1 (de)	2007-12-12
PL371934A1 (en)	2005-07-11
KR20040111466A (ko)	2004-12-31
CN1649932A (zh)	2005-08-03
IL164977A (en)	2007-12-03
ZA200408854B (en)	2005-11-02
DE60318035T2 (de)	2008-12-11
NO20045283L (no)	2005-01-07
TWI310388B (en)	2009-06-01
EA008244B1 (ru)	2007-04-27
EP1504047A1 (de)	2005-02-09
ES2298510T3 (es)	2008-05-16
CN1290893C (zh)	2006-12-20
AR039522A1 (es)	2005-02-23
MY139066A (en)	2009-08-28
CA2483282A1 (en)	2003-11-13
BR0309688A (pt)	2005-02-22
NZ536294A (en)	2005-05-27
IL164977A0 (en)	2005-12-18
JP2005524730A (ja)	2005-08-18
MXPA04010778A (es)	2005-03-07
EA200401465A1 (ru)	2005-04-28
US20110112115A1 (en)	2011-05-12
TW200413434A (en)	2004-08-01
US20150086504A1 (en)	2015-03-26
AU2003222310B2 (en)	2009-04-09
AU2003222310A1 (en)	2003-11-17
DE60318035D1 (de)	2008-01-24

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