ATE381330T1 - Il-8 rezeptor-antagonisten - Google Patents
Il-8 rezeptor-antagonistenInfo
- Publication number
- ATE381330T1 ATE381330T1 AT98901852T AT98901852T ATE381330T1 AT E381330 T1 ATE381330 T1 AT E381330T1 AT 98901852 T AT98901852 T AT 98901852T AT 98901852 T AT98901852 T AT 98901852T AT E381330 T1 ATE381330 T1 AT E381330T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor antagonists
- antagonists
- receptor
- Prior art date
Links
- 108090001007 Interleukin-8 Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3599097P | 1997-01-23 | 1997-01-23 | |
| US4283097P | 1997-04-08 | 1997-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE381330T1 true ATE381330T1 (de) | 2008-01-15 |
Family
ID=26712686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98901852T ATE381330T1 (de) | 1997-01-23 | 1998-01-23 | Il-8 rezeptor-antagonisten |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6166055A (de) |
| EP (1) | EP1005341B1 (de) |
| JP (1) | JP2002515055A (de) |
| KR (1) | KR20000070369A (de) |
| CN (1) | CN1253501A (de) |
| AR (1) | AR008331A1 (de) |
| AT (1) | ATE381330T1 (de) |
| AU (1) | AU729893B2 (de) |
| BR (1) | BR9807085A (de) |
| CA (1) | CA2278427A1 (de) |
| DE (1) | DE69838874T2 (de) |
| ES (1) | ES2299200T3 (de) |
| HU (1) | HUP0001940A3 (de) |
| IL (1) | IL131005A0 (de) |
| NO (1) | NO313913B1 (de) |
| NZ (1) | NZ336859A (de) |
| PE (1) | PE103699A1 (de) |
| PL (1) | PL334774A1 (de) |
| TR (1) | TR199901761T2 (de) |
| WO (1) | WO1998032438A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| AR015426A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion |
| AR015425A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion |
| WO2000021963A1 (en) * | 1998-10-13 | 2000-04-20 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| WO2000069435A1 (en) * | 1999-05-18 | 2000-11-23 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| JP2003505379A (ja) * | 1999-07-16 | 2003-02-12 | ビーエーエスエフ アクチェンゲゼルシャフト | 置換ベンゾイソチアゾール化合物 |
| US6440993B1 (en) | 1999-10-12 | 2002-08-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| PE20011124A1 (es) | 2000-03-31 | 2001-10-28 | Upjohn Co | Nuevos agentes antibacterianos de benzosultam oxazolidinona |
| DE10038709A1 (de) | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen |
| GB0403038D0 (en) | 2004-02-11 | 2004-03-17 | Novartis Ag | Organic compounds |
| CN1984899B (zh) | 2004-05-12 | 2011-07-27 | 先灵公司 | Cxcr1和cxcr2趋化因子拮抗剂 |
| AR065369A1 (es) | 2007-02-19 | 2009-06-03 | Novartis Ag | Derivados de ciclohexil - amida del acido aril- carboxilico |
| CN107674071B (zh) | 2012-05-11 | 2021-12-31 | 同步制药公司 | 作为隐花色素调节剂的含有咔唑的磺酰胺类 |
| TWI690521B (zh) | 2014-04-07 | 2020-04-11 | 美商同步製藥公司 | 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09511998A (ja) * | 1994-04-15 | 1997-12-02 | グラクソ、ウェルカム、インコーポレーテッド | 1,4 − ベンゾジアゼピン化合物を用いたコレシストキニンアゴニスト活性の誘導方法 |
| JP3720395B2 (ja) * | 1994-09-20 | 2005-11-24 | 京都薬品工業株式会社 | 新規ヘテロ環誘導体、その製造方法およびその医薬用途 |
| DK0866059T3 (da) * | 1995-10-05 | 2002-03-25 | Kyoto Pharma Ind | Nye heterocykliske derivater og medicinsk anvendelse deraf |
| US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| AR015426A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion |
| AR015425A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion |
| CA2318195A1 (en) * | 1998-01-16 | 1999-07-22 | Deborah Lynne Bryan | Il-8 receptor antagonists |
-
1998
- 1998-01-22 AR ARP980100284A patent/AR008331A1/es not_active Application Discontinuation
- 1998-01-23 US US09/341,382 patent/US6166055A/en not_active Expired - Fee Related
- 1998-01-23 JP JP53213998A patent/JP2002515055A/ja not_active Ceased
- 1998-01-23 IL IL13100598A patent/IL131005A0/xx unknown
- 1998-01-23 HU HU0001940A patent/HUP0001940A3/hu unknown
- 1998-01-23 WO PCT/US1998/001292 patent/WO1998032438A1/en not_active Ceased
- 1998-01-23 PL PL98334774A patent/PL334774A1/xx unknown
- 1998-01-23 CN CN98803564A patent/CN1253501A/zh active Pending
- 1998-01-23 CA CA002278427A patent/CA2278427A1/en not_active Abandoned
- 1998-01-23 ES ES98901852T patent/ES2299200T3/es not_active Expired - Lifetime
- 1998-01-23 EP EP98901852A patent/EP1005341B1/de not_active Expired - Lifetime
- 1998-01-23 AU AU58278/98A patent/AU729893B2/en not_active Ceased
- 1998-01-23 DE DE69838874T patent/DE69838874T2/de not_active Expired - Fee Related
- 1998-01-23 NZ NZ336859A patent/NZ336859A/xx unknown
- 1998-01-23 BR BR9807085-1A patent/BR9807085A/pt not_active Application Discontinuation
- 1998-01-23 TR TR1999/01761T patent/TR199901761T2/xx unknown
- 1998-01-23 KR KR1019997006602A patent/KR20000070369A/ko not_active Ceased
- 1998-01-23 AT AT98901852T patent/ATE381330T1/de not_active IP Right Cessation
- 1998-07-22 PE PE1998000656A patent/PE103699A1/es not_active Application Discontinuation
-
1999
- 1999-07-22 NO NO19993585A patent/NO313913B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PE103699A1 (es) | 1999-12-30 |
| NO313913B1 (no) | 2002-12-23 |
| EP1005341A4 (de) | 2004-09-08 |
| CA2278427A1 (en) | 1998-07-30 |
| BR9807085A (pt) | 2000-04-18 |
| NO993585D0 (no) | 1999-07-22 |
| PL334774A1 (en) | 2000-03-13 |
| KR20000070369A (ko) | 2000-11-25 |
| WO1998032438A1 (en) | 1998-07-30 |
| DE69838874D1 (de) | 2008-01-31 |
| JP2002515055A (ja) | 2002-05-21 |
| NO993585L (no) | 1999-09-21 |
| TR199901761T2 (xx) | 1999-10-21 |
| CN1253501A (zh) | 2000-05-17 |
| NZ336859A (en) | 2001-01-26 |
| AU729893B2 (en) | 2001-02-15 |
| EP1005341A1 (de) | 2000-06-07 |
| AR008331A1 (es) | 1999-12-29 |
| HUP0001940A3 (en) | 2002-09-30 |
| ES2299200T3 (es) | 2008-05-16 |
| DE69838874T2 (de) | 2008-12-04 |
| AU5827898A (en) | 1998-08-18 |
| EP1005341B1 (de) | 2007-12-19 |
| HUP0001940A2 (hu) | 2001-01-29 |
| IL131005A0 (en) | 2001-01-28 |
| US6166055A (en) | 2000-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |