ATE381339T1 - Aerosol-formulierungen mit estern von 3,17- dihydroxyöstratrien-derivaten zur pulmonalen abgabe - Google Patents

Aerosol-formulierungen mit estern von 3,17- dihydroxyöstratrien-derivaten zur pulmonalen abgabe

Info

Publication number
ATE381339T1
ATE381339T1 AT03743324T AT03743324T ATE381339T1 AT E381339 T1 ATE381339 T1 AT E381339T1 AT 03743324 T AT03743324 T AT 03743324T AT 03743324 T AT03743324 T AT 03743324T AT E381339 T1 ATE381339 T1 AT E381339T1
Authority
AT
Austria
Prior art keywords
esters
derivatives
dihydroxyestrien
pulmonary delivery
aerosol formulations
Prior art date
Application number
AT03743324T
Other languages
English (en)
Inventor
Rebecca Davies
David Ganderton
David Lewis
Brian Meakin
Gaetano Brambilla
Alessandra Ferraris
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE381339T1 publication Critical patent/ATE381339T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
AT03743324T 2002-03-01 2003-02-24 Aerosol-formulierungen mit estern von 3,17- dihydroxyöstratrien-derivaten zur pulmonalen abgabe ATE381339T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02004787A EP1340503A1 (de) 2002-03-01 2002-03-01 Lösung Aerosol Formulierung von Estern von 3,17-dihydroxy Oestratrien-Derivaten zur Lungenverabreichung

Publications (1)

Publication Number Publication Date
ATE381339T1 true ATE381339T1 (de) 2008-01-15

Family

ID=27675680

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03743324T ATE381339T1 (de) 2002-03-01 2003-02-24 Aerosol-formulierungen mit estern von 3,17- dihydroxyöstratrien-derivaten zur pulmonalen abgabe

Country Status (9)

Country Link
US (1) US20050209207A1 (de)
EP (2) EP1340503A1 (de)
AT (1) ATE381339T1 (de)
AU (1) AU2003215588A1 (de)
BR (1) BR0303347A (de)
DE (1) DE60318182T2 (de)
ES (1) ES2297183T3 (de)
NO (1) NO20034873L (de)
WO (1) WO2003074058A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1100723A2 (en) * 2011-12-28 2013-06-28 Avidin Kft Use of estrogen derivatives for preparing medicament for the treatment of psychiatric diseases
WO2025039045A1 (en) * 2023-08-23 2025-02-27 Inhaler Supplies Pty Ltd Inhalable formulation for volatile actives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1099722A (en) * 1964-04-20 1968-01-17 Takeda Chemical Industries Ltd Aerosol
DE2758549A1 (de) * 1977-12-23 1979-07-05 Schering Ag Pharmazeutische zubereitung
US4315925A (en) * 1980-05-30 1982-02-16 University Of Kentucky Research Foundation Method of administering natural female sex hormones
US5043331A (en) * 1989-06-15 1991-08-27 Orion-Yhtyma Oy Treatment of postmenopausal disorders
ATE114112T1 (de) * 1990-10-18 1994-12-15 Minnesota Mining & Mfg Aerosolzubereitung, die beclometason 17,21- dipropionat enthält.
US6461591B1 (en) * 1997-02-05 2002-10-08 Jago Research Ag Medical aerosol formulations
US6126919A (en) * 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
GB2326334A (en) * 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
AU740758B2 (en) * 1997-10-28 2001-11-15 Vivus, Inc. Treatment of female sexual dysfunction
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6117446A (en) * 1999-01-26 2000-09-12 Place; Virgil A. Drug dosage unit for buccal administration of steroidal active agents

Also Published As

Publication number Publication date
DE60318182T2 (de) 2008-12-04
WO2003074058A1 (en) 2003-09-12
EP1340503A1 (de) 2003-09-03
EP1480651B1 (de) 2007-12-19
NO20034873D0 (no) 2003-10-31
AU2003215588A1 (en) 2003-09-16
EP1480651A1 (de) 2004-12-01
BR0303347A (pt) 2004-07-13
US20050209207A1 (en) 2005-09-22
ES2297183T3 (es) 2008-05-01
DE60318182D1 (de) 2008-01-31
NO20034873L (no) 2003-12-23

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