ATE381615T1 - Nukleinsäure-enzym zur spaltung von rna - Google Patents

Nukleinsäure-enzym zur spaltung von rna

Info

Publication number
ATE381615T1
ATE381615T1 AT99919000T AT99919000T ATE381615T1 AT E381615 T1 ATE381615 T1 AT E381615T1 AT 99919000 T AT99919000 T AT 99919000T AT 99919000 T AT99919000 T AT 99919000T AT E381615 T1 ATE381615 T1 AT E381615T1
Authority
AT
Austria
Prior art keywords
nucleotide
enzyme
cleavage site
line
formulae
Prior art date
Application number
AT99919000T
Other languages
English (en)
Inventor
Jean-Pierre Perreault
Sirinart Ananvoranich
Daniel Lafontaine
Original Assignee
Commercialisation Des Produits
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commercialisation Des Produits filed Critical Commercialisation Des Produits
Application granted granted Critical
Publication of ATE381615T1 publication Critical patent/ATE381615T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/12Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/123Hepatitis delta

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AT99919000T 1998-04-29 1999-04-29 Nukleinsäure-enzym zur spaltung von rna ATE381615T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002230203A CA2230203A1 (en) 1998-04-29 1998-04-29 Delta ribozyme for rna cleavage

Publications (1)

Publication Number Publication Date
ATE381615T1 true ATE381615T1 (de) 2008-01-15

Family

ID=4162136

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99919000T ATE381615T1 (de) 1998-04-29 1999-04-29 Nukleinsäure-enzym zur spaltung von rna

Country Status (7)

Country Link
US (1) US7148044B1 (de)
EP (1) EP1073731B1 (de)
AT (1) ATE381615T1 (de)
AU (1) AU3695699A (de)
CA (1) CA2230203A1 (de)
DE (1) DE69937791D1 (de)
WO (1) WO1999055856A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012140B2 (en) 2004-07-06 2015-04-21 Societe de Commercialisation des Produits de la Recherche Appliquée Socpra Sciences et Génie S.E.C. Target-dependent nucleic acid adapter
CN103917664B (zh) * 2011-09-09 2018-06-15 斯比戴克斯私人有限公司 核酸酶底物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225337A (en) 1989-09-25 1993-07-06 Innovir Laboratories, Inc. Ribozyme compositions and methods for use
ES2061416T3 (es) 1990-10-12 1997-03-01 Max Planck Gesellschaft Ribozimas modificadas.
FR2680797A1 (fr) * 1991-09-03 1993-03-05 Genset Sa Structure ribozymique derivee de l'arn genomique du virus de l'hepatite delta.
JPH07502898A (ja) 1992-01-13 1995-03-30 デューク・ユニバーシティー 酵素rna分子
EP0786522A2 (de) 1992-07-17 1997-07-30 Ribozyme Pharmaceuticals, Inc. Enzymatische RNA-Moleküle zur Behandlung von stenotischen Zuständen

Also Published As

Publication number Publication date
WO1999055856A3 (en) 1999-12-16
AU3695699A (en) 1999-11-16
WO1999055856A2 (en) 1999-11-04
EP1073731B1 (de) 2007-12-19
EP1073731A2 (de) 2001-02-07
DE69937791D1 (de) 2008-01-31
CA2230203A1 (en) 1999-10-29
US7148044B1 (en) 2006-12-12

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Legal Events

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