ATE381615T1 - Nukleinsäure-enzym zur spaltung von rna - Google Patents
Nukleinsäure-enzym zur spaltung von rnaInfo
- Publication number
- ATE381615T1 ATE381615T1 AT99919000T AT99919000T ATE381615T1 AT E381615 T1 ATE381615 T1 AT E381615T1 AT 99919000 T AT99919000 T AT 99919000T AT 99919000 T AT99919000 T AT 99919000T AT E381615 T1 ATE381615 T1 AT E381615T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleotide
- enzyme
- cleavage site
- line
- formulae
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 9
- 108090000790 Enzymes Proteins 0.000 title abstract 9
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 12
- 125000003729 nucleotide group Chemical group 0.000 abstract 12
- 238000003776 cleavage reaction Methods 0.000 abstract 11
- 230000007017 scission Effects 0.000 abstract 11
- 239000000758 substrate Substances 0.000 abstract 7
- 108091028664 Ribonucleotide Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002336 ribonucleotide Substances 0.000 abstract 1
- 125000002652 ribonucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/123—Hepatitis delta
Landscapes
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002230203A CA2230203A1 (en) | 1998-04-29 | 1998-04-29 | Delta ribozyme for rna cleavage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE381615T1 true ATE381615T1 (de) | 2008-01-15 |
Family
ID=4162136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99919000T ATE381615T1 (de) | 1998-04-29 | 1999-04-29 | Nukleinsäure-enzym zur spaltung von rna |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7148044B1 (de) |
| EP (1) | EP1073731B1 (de) |
| AT (1) | ATE381615T1 (de) |
| AU (1) | AU3695699A (de) |
| CA (1) | CA2230203A1 (de) |
| DE (1) | DE69937791D1 (de) |
| WO (1) | WO1999055856A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9012140B2 (en) | 2004-07-06 | 2015-04-21 | Societe de Commercialisation des Produits de la Recherche Appliquée Socpra Sciences et Génie S.E.C. | Target-dependent nucleic acid adapter |
| CN103917664B (zh) * | 2011-09-09 | 2018-06-15 | 斯比戴克斯私人有限公司 | 核酸酶底物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225337A (en) | 1989-09-25 | 1993-07-06 | Innovir Laboratories, Inc. | Ribozyme compositions and methods for use |
| ES2061416T3 (es) | 1990-10-12 | 1997-03-01 | Max Planck Gesellschaft | Ribozimas modificadas. |
| FR2680797A1 (fr) * | 1991-09-03 | 1993-03-05 | Genset Sa | Structure ribozymique derivee de l'arn genomique du virus de l'hepatite delta. |
| JPH07502898A (ja) | 1992-01-13 | 1995-03-30 | デューク・ユニバーシティー | 酵素rna分子 |
| EP0786522A2 (de) | 1992-07-17 | 1997-07-30 | Ribozyme Pharmaceuticals, Inc. | Enzymatische RNA-Moleküle zur Behandlung von stenotischen Zuständen |
-
1998
- 1998-04-29 CA CA002230203A patent/CA2230203A1/en not_active Abandoned
-
1999
- 1999-04-29 AT AT99919000T patent/ATE381615T1/de not_active IP Right Cessation
- 1999-04-29 DE DE69937791T patent/DE69937791D1/de not_active Expired - Lifetime
- 1999-04-29 WO PCT/CA1999/000391 patent/WO1999055856A2/en not_active Ceased
- 1999-04-29 AU AU36956/99A patent/AU3695699A/en not_active Abandoned
- 1999-04-29 EP EP99919000A patent/EP1073731B1/de not_active Expired - Lifetime
-
2000
- 2000-10-30 US US09/699,667 patent/US7148044B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999055856A3 (en) | 1999-12-16 |
| AU3695699A (en) | 1999-11-16 |
| WO1999055856A2 (en) | 1999-11-04 |
| EP1073731B1 (de) | 2007-12-19 |
| EP1073731A2 (de) | 2001-02-07 |
| DE69937791D1 (de) | 2008-01-31 |
| CA2230203A1 (en) | 1999-10-29 |
| US7148044B1 (en) | 2006-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2001068836A3 (en) | Methods and compositions for rna interference | |
| WO2004042029A3 (en) | Oligomers comprising modified bases for binding cytosine and uracil or thymine and their use | |
| DE69736598D1 (de) | Ribonukleaseresistente rna präparation und seine verwendung | |
| ATE394504T1 (de) | Verfahren zur dns- oder rns-sequenzierung | |
| DE69534855D1 (de) | Enzymaktive dna moleküle | |
| IL98543A0 (en) | Endonuclease and its use in the cleavage of a target nucleic acid sequence | |
| WO2003062394A3 (en) | Methods and compositions for rna interference | |
| DE60140676D1 (de) | Mediatoren von rns-interferenz, die rns-sequenzspezifisch sind | |
| MXPA05001355A (es) | Formas nuevas adicionales de moleculas de arn de interferencia. | |
| BR9407712A (pt) | Métodos e composiçoes para sequenciamento eficaz de ácidos nuclêicos | |
| DE69403642D1 (de) | 7-deazapurin modifizierte oligonukleotide | |
| WO2003048378A3 (en) | Methods and compositions for selectively cleaving dna containing duplex acids in a complex nucleic acid mixture | |
| CA2287520A1 (en) | Enzymatic dna molecules | |
| WO1998026093A3 (en) | Fluorescent nucleotide analog hairpin formation for detection of nucleic acid hybridization | |
| Grant et al. | Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation | |
| ID27760A (id) | Poliketida-poliketida, pembuatannya, dan bahan-bahan untuk penggunaannya | |
| AU1204600A (en) | Systems and methods for sequencing by hybridization | |
| CA2180722A1 (en) | A method of sequencing short oligonucleotides | |
| ATE381615T1 (de) | Nukleinsäure-enzym zur spaltung von rna | |
| WO2001044266A3 (en) | Nucleic acid compounds and screening assays using the same | |
| WO2001002609A3 (en) | Method of identifying toxic agents using differential gene expression | |
| DK0857220T3 (da) | Sekvensmodifikation af oligonucleotidprimere til manipulering af ikke-templateret nucleotidaddition | |
| ATE381616T1 (de) | Regulation der upa gen-expression durch methylierte nukleotide | |
| WO2002059366A3 (en) | Rna polymers and uses thereof | |
| EP1221491B8 (de) | System und verfahren zum sequenzieren genetischer substanzen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |