ATE381932T1 - Liposomale zubereitungen von indolocarbazol- derivaten - Google Patents

Liposomale zubereitungen von indolocarbazol- derivaten

Info

Publication number: ATE381932T1
Authority: AT; Austria
Prior art keywords: indolocarbazole derivatives; liposomal preparations; liposome; indolocarbazole; derivatives
Prior art date: 1996-06-18

Application number

AT97926234T

Other languages

English (en)

Inventor

Yasuki Kato

Masahiro Yamauchi

Kunio Ito

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-18

Filing date

1997-06-12

Publication date

2008-01-15

1997-06-12 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

2008-01-15 Application granted granted Critical

2008-01-15 Publication of ATE381932T1 publication Critical patent/ATE381932T1/de

Links

VVVPGLRKXQSQSZ-UHFFFAOYSA-N indolo[3,2-c]carbazole Chemical class C1=CC=CC2=NC3=C4C5=CC=CC=C5N=C4C=CC3=C21 VVVPGLRKXQSQSZ-UHFFFAOYSA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
239000002502 liposome Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Dispersion Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT97926234T 1996-06-18 1997-06-12 Liposomale zubereitungen von indolocarbazol- derivaten ATE381932T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP15645996		1996-06-18

Publications (1)

Publication Number	Publication Date
ATE381932T1 true ATE381932T1 (de)	2008-01-15

Family

ID=15628218

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97926234T ATE381932T1 (de)	1996-06-18	1997-06-12	Liposomale zubereitungen von indolocarbazol- derivaten

Country Status (10)

Country	Link
US (1)	US6045822A (de)
EP (1)	EP0850646B1 (de)
AT (1)	ATE381932T1 (de)
AU (1)	AU718856B2 (de)
CA (1)	CA2229892C (de)
DE (1)	DE69738416T2 (de)
DK (1)	DK0850646T3 (de)
ES (1)	ES2296311T3 (de)
PT (1)	PT850646E (de)
WO (1)	WO1997048398A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7795246B2 (en)	1998-08-06	2010-09-14	Cephalon, Inc.	Particle-forming compositions containing fused pyrrolocarbazoles
US6200968B1 (en) *	1998-08-06	2001-03-13	Cephalon, Inc.	Particle-forming compositions containing fused pyrrolocarbazoles
CA2376849C (en) *	1999-06-24	2008-10-14	Kyowa Hakko Kogyo Co., Ltd.	Method of inhibiting leakage of drug encapsulated in liposomes
DK1347743T3 (da) *	2000-12-07	2006-07-03	Univ Utrecht Holding Bv	Præparat til behandling af inflammatoriske lidelser
US7396852B2 (en) *	2005-11-16	2008-07-08	Xerox Corporation	Compound having indolocarbazole moiety and divalent linkage
US20060124921A1 (en) *	2004-12-14	2006-06-15	Xerox Corporation	Compound with indolocarbazole moieties and devices containing such compound
TWI468188B (zh)	2008-01-30	2015-01-11	Univ Tokushima	Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation
JP5638204B2 (ja) *	2009-05-29	2014-12-10	国立大学法人岡山大学	経口投与用リポソーム製剤およびその製造方法
EP2883542B1 (de)	2012-08-10	2019-05-01	Taiho Pharmaceutical Co., Ltd.	Stabile oxaliplatin-verkapselnde wässrige liposomdispersion und stabilisierungsverfahren dafür

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0383919A4 (en) *	1988-02-04	1992-08-05	Kyowa Hakko Kogyo Co., Ltd.	Staurosporin derivatives
US4952567A (en) *	1988-05-09	1990-08-28	City Of Hope	Inhibition of lipogenesis
JP2694701B2 (ja) *	1989-08-24	1997-12-24	日本油脂株式会社	液体膜制癌剤
IL100833A0 (en) *	1991-02-20	1992-09-06	Greenwich Pharma	Method for synthesis of ethereally substituted blocked monosaccharides
JPH07278016A (ja) *	1994-04-13	1995-10-24	Pola Chem Ind Inc	抗癌剤リポソーム製剤
EP0711557A1 (de) *	1994-11-09	1996-05-15	Ciba-Geigy Ag	Pharmazeutische Formulierungsgrundlage

1997
- 1997-06-12 DK DK97926234T patent/DK0850646T3/da active
- 1997-06-12 ES ES97926234T patent/ES2296311T3/es not_active Expired - Lifetime
- 1997-06-12 AT AT97926234T patent/ATE381932T1/de not_active IP Right Cessation
- 1997-06-12 WO PCT/JP1997/002033 patent/WO1997048398A1/ja not_active Ceased
- 1997-06-12 EP EP97926234A patent/EP0850646B1/de not_active Expired - Lifetime
- 1997-06-12 PT PT97926234T patent/PT850646E/pt unknown
- 1997-06-12 CA CA002229892A patent/CA2229892C/en not_active Expired - Fee Related
- 1997-06-12 AU AU31066/97A patent/AU718856B2/en not_active Ceased
- 1997-06-12 DE DE69738416T patent/DE69738416T2/de not_active Expired - Fee Related
1998
- 1998-02-18 US US09/025,752 patent/US6045822A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK0850646T3 (da)	2008-05-13
PT850646E (pt)	2008-03-31
DE69738416T2 (de)	2008-12-11
EP0850646B1 (de)	2007-12-26
CA2229892C (en)	2003-01-07
EP0850646A4 (de)	2005-06-22
AU3106697A (en)	1998-01-07
EP0850646A1 (de)	1998-07-01
US6045822A (en)	2000-04-04
DE69738416D1 (de)	2008-02-07
ES2296311T3 (es)	2008-04-16
WO1997048398A1 (en)	1997-12-24
AU718856B2 (en)	2000-04-20
CA2229892A1 (en)	1997-12-24

Legal Events

Date

Code

Title

Description

2008-07-15

UEP

Publication of translation of european patent specification

Ref document number: 0850646

Country of ref document: EP

2010-03-15

REN

Ceased due to non-payment of the annual fee

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HN1998000036A (es)	1999-08-23	Compuesto de pirazina
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ATE263771T1 (de)	2004-04-15	Totalsynthese von acylfulvenen mit antitumorwirkung
GR3004139T3 (de)	1993-03-31
DE69511424D1 (de)	1999-09-16	Antifungale sordaridinderivate
ATE172463T1 (de)	1998-11-15	Pyrrolocarbazol
DE69738416D1 (de)	2008-02-07	Liposomale zubereitungen von indolocarbazol-derivaten
DE69621469D1 (de)	2002-07-04	Phenylpiperidin-derivate
AU1634388A (en)	1988-11-24	Cyclic anticoagulant peptides
AU1634288A (en)	1988-11-24	Cyclic anticoagulant peptides
EP1000923A4 (de)	2001-02-07	Cyclopentenonderivate
AU626070B2 (en)	1992-07-23	Anticoagulant peptide alcohols
AU7591187A (en)	1988-01-28	Novel fungicidal compositions
FI901277A0 (fi)	1990-03-14	2,5,6,7-tetranor-4,8-inter-m-fenylen pg1z-derivativ.
FI910366A0 (fi)	1991-01-24	Menetelmä deoksimulundokandiinin valmistamiseksi
TR200001871T2 (tr)	2001-01-22	İmmünmodülatör bileşikler içeren gamma-glutamil ve beta-aspartil ve ilgili yöntemler.
ES2164258T3 (es)	2002-02-16	Procedimiento de preparacion de derivados de carbamoilmetilurea.
TH44959A (th)	2001-04-30	อนุพันธ์รีซอร์ซินอล