ATE382336T1 - Verfahren zur herstellung von partikeln und deren produkte - Google Patents
Verfahren zur herstellung von partikeln und deren produkteInfo
- Publication number
- ATE382336T1 ATE382336T1 AT01978670T AT01978670T ATE382336T1 AT E382336 T1 ATE382336 T1 AT E382336T1 AT 01978670 T AT01978670 T AT 01978670T AT 01978670 T AT01978670 T AT 01978670T AT E382336 T1 ATE382336 T1 AT E382336T1
- Authority
- AT
- Austria
- Prior art keywords
- particle
- active substance
- additive
- particle surface
- products
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 8
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000654 additive Substances 0.000 abstract 5
- 230000000996 additive effect Effects 0.000 abstract 5
- 239000013543 active substance Substances 0.000 abstract 4
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000002344 surface layer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/30—Physical treatment, e.g. electrical or magnetic means, wave energy or irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
- B01D9/0054—Use of anti-solvent
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Glanulating (AREA)
- Disintegrating Or Milling (AREA)
- Formation And Processing Of Food Products (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0027357A GB0027357D0 (en) | 2000-11-09 | 2000-11-09 | Particle formation methods and their products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE382336T1 true ATE382336T1 (de) | 2008-01-15 |
Family
ID=9902848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01978670T ATE382336T1 (de) | 2000-11-09 | 2001-11-01 | Verfahren zur herstellung von partikeln und deren produkte |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US7115280B2 (de) |
| EP (1) | EP1331928B1 (de) |
| JP (1) | JP4880863B2 (de) |
| KR (1) | KR100822098B1 (de) |
| AT (1) | ATE382336T1 (de) |
| AU (2) | AU2002210765B9 (de) |
| CA (1) | CA2426247C (de) |
| DE (1) | DE60132230T2 (de) |
| ES (1) | ES2299519T3 (de) |
| GB (3) | GB0027357D0 (de) |
| MX (1) | MXPA03003846A (de) |
| TW (1) | TWI241198B (de) |
| WO (1) | WO2002038127A2 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9703673D0 (en) * | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
| GB9810559D0 (en) * | 1998-05-15 | 1998-07-15 | Bradford Particle Design Ltd | Method and apparatus for particle formation |
| DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
| US8268333B2 (en) * | 2001-04-24 | 2012-09-18 | Lintec Corporation | Orally administered agent and an orally administered agent/supporting substrate complex |
| JP4993652B2 (ja) * | 2004-03-31 | 2012-08-08 | リンテック株式会社 | 経口投与剤 |
| JP4267926B2 (ja) * | 2001-04-24 | 2009-05-27 | リンテック株式会社 | 経口投与剤及び経口投与剤保持体 |
| GB0117696D0 (en) * | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| US7582284B2 (en) | 2002-04-17 | 2009-09-01 | Nektar Therapeutics | Particulate materials |
| GB0216562D0 (en) | 2002-04-25 | 2002-08-28 | Bradford Particle Design Ltd | Particulate materials |
| US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
| US20040202681A1 (en) * | 2002-12-19 | 2004-10-14 | Baxter International, Inc. | Process for preparing pharmaceutical formulations using supercritical fluids |
| GB0310636D0 (en) * | 2003-05-08 | 2003-06-11 | Nektar Therapeutics Uk Ltd | Particulate materials |
| KR20060015587A (ko) * | 2003-05-08 | 2006-02-17 | 넥타 쎄라퓨틱스 유케이 리미티드 | 미립물 |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| KR100603974B1 (ko) | 2003-12-05 | 2006-07-25 | 김갑식 | 고체상 지질을 용매로 이용한 나노수준의 또는 비결정질입자의 제조 방법 |
| WO2005072710A2 (en) | 2004-01-28 | 2005-08-11 | Johns Hopkins University | Drugs and gene carrier particles that rapidly move through mucous barriers |
| JP2005298471A (ja) * | 2004-03-17 | 2005-10-27 | Lintec Corp | 薬剤の製造方法 |
| JP2005289867A (ja) * | 2004-03-31 | 2005-10-20 | Lintec Corp | 経口投与剤 |
| US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
| US7351423B2 (en) * | 2004-09-01 | 2008-04-01 | Depuy Spine, Inc. | Musculo-skeletal implant having a bioactive gradient |
| EP2098225B8 (de) * | 2005-01-06 | 2011-06-22 | Cima Labs Inc. | Geschmacksunterdrückungssystem für nicht weichgemachte Arzneimittel |
| AU2006272438B2 (en) * | 2005-07-15 | 2011-08-04 | Map Pharmaceuticals, Inc. | Method of particle formation |
| GB0602637D0 (en) * | 2006-02-09 | 2006-03-22 | Glaxo Group Ltd | Novel process |
| CN101489538B (zh) * | 2006-05-23 | 2014-01-08 | 武田药品工业株式会社 | 包含吡格列酮的口服制剂 |
| DE602007012559D1 (de) * | 2006-09-08 | 2011-03-31 | Univ Johns Hopkins | H die schleimhaut |
| WO2008070279A2 (en) * | 2006-10-11 | 2008-06-12 | Crititech, Inc. | Method for precipitation of small medicament particles into use containers |
| WO2008064259A2 (en) * | 2006-11-21 | 2008-05-29 | Biokey, Inc. | Solid dispersion composition comprising fluvastatin |
| CA2677838C (en) | 2007-02-11 | 2017-08-01 | Map Pharmaceuticals, Inc. | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
| WO2009085828A2 (en) * | 2007-12-20 | 2009-07-09 | Mutual Pharmaceutical Company, Inc. | Quinine sulfate polymorphs, processes of preparing, compositions and uses thereof |
| US20090197963A1 (en) * | 2008-02-01 | 2009-08-06 | Dan Llewellyn | Method and compositions for suppressing appetite or treating obesity |
| WO2010002675A2 (en) * | 2008-06-30 | 2010-01-07 | Mutual Pharmaceutical Company, Inc. | Quinine sulfate/bisulfate solid complex; methods of making; and methods of use thereof |
| VN27088A1 (en) * | 2008-07-31 | 2011-08-25 | Feyecon Bv | Microencapsulate and process for the manufacture thereof. |
| EP2538929A4 (de) | 2010-02-25 | 2014-07-09 | Univ Johns Hopkins | Verzögerte freisetzung von therapiemitteln in einen teil des auges |
| JP5793179B2 (ja) | 2010-03-22 | 2015-10-14 | バイオ−シネクティクス インク.Bio−Synectics Inc. | ナノ粒子の製造方法 |
| WO2012109363A2 (en) | 2011-02-08 | 2012-08-16 | The Johns Hopkins University | Mucus penetrating gene carriers |
| MX350838B (es) | 2011-02-11 | 2017-09-18 | Grain Proc Corporation * | Composicion de sal. |
| CN104363924B (zh) | 2012-03-16 | 2018-04-17 | 约翰霍普金斯大学 | 用于递送hif‑1抑制剂的控制释放调配物 |
| JP6138904B2 (ja) | 2012-03-16 | 2017-05-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート |
| KR102140989B1 (ko) | 2012-05-03 | 2020-08-04 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| ES3055223T3 (en) | 2012-05-03 | 2026-02-10 | Alcon Inc | Pharmaceutical nanoparticles showing improved mucosal transport |
| US9533068B2 (en) | 2012-05-04 | 2017-01-03 | The Johns Hopkins University | Drug loaded microfiber sutures for ophthalmic application |
| WO2014078063A2 (en) * | 2012-11-14 | 2014-05-22 | Pepsico, Inc. | Method to improve dispersibility of a material having low solubility in water |
| US10568975B2 (en) | 2013-02-05 | 2020-02-25 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| HK1217092A1 (zh) | 2013-02-15 | 2016-12-23 | Kala Pharmaceuticals, Inc. | 治疗性化合物及其用途 |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| BR112015020139A2 (pt) | 2013-02-20 | 2017-07-18 | Kala Pharmaceuticals Inc | compostos terapêuticos e usos dos mesmos |
| BR112015024234B1 (pt) | 2013-03-21 | 2022-11-16 | Eupraxia Pharmaceuticals USA LLC | Composição farmacêutica de liberação sustentada injetável, uso da mesma para diminuir inflamação ou controlar dor e método para formar micropartículas revestidas |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| KR20160099084A (ko) | 2013-11-01 | 2016-08-19 | 칼라 파마슈티컬스, 인크. | 치료 화합물의 결정질 형태 및 그의 용도 |
| CA2960860A1 (en) * | 2014-09-19 | 2016-03-24 | Eupraxia Pharmaceuticals Inc. | Injectable microparticles for hyper-localized release of therapeutic agents |
| US10485757B2 (en) | 2015-01-27 | 2019-11-26 | The Johns Hopkins University | Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces |
| ES2672993T3 (es) | 2015-10-27 | 2018-06-19 | Eupraxia Pharmaceuticals Inc. | Formulaciones de liberación sostenida de anestésicos locales |
| MX2018005932A (es) | 2015-11-12 | 2019-05-20 | Graybug Vision Inc | Microparticulas aglomerantes para terapia medica. |
| CA3036065A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3509423A4 (de) | 2016-09-08 | 2020-05-13 | Kala Pharmaceuticals, Inc. | Kristalline formen von therapeutischen verbindungen und verwendungen davon |
| CA3036336A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3600324A4 (de) | 2017-03-23 | 2020-12-09 | Graybug Vision, Inc. | Arzneimittel und zusammensetzungen zur behandlung von augenkrankheiten |
| MX2019013363A (es) | 2017-05-10 | 2020-01-13 | Graybug Vision Inc | Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica. |
| US12496279B2 (en) | 2019-04-11 | 2025-12-16 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
Family Cites Families (157)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1122284A (en) | 1965-03-19 | 1968-08-07 | Fisons Pharmaceuticals Ltd | Inhalation device |
| JPS5254709A (en) * | 1975-10-31 | 1977-05-04 | Lion Corp | Multi-stage spray drying method |
| SE418247B (sv) * | 1975-11-17 | 1981-05-18 | Haessle Ab | Sett att framstella kroppar med reglerad frigoring av en aktiv komponent |
| FI54093C (fi) * | 1976-12-20 | 1978-10-10 | Outokumpu Oy | Saett att framstaella pulverformigt selen fraon raoselen |
| DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
| JPS6034925B2 (ja) * | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| EP0050650A1 (de) * | 1980-04-21 | 1982-05-05 | University Of Southern California | Arzneiformulierung mit verlängerter aktion |
| US4423099A (en) * | 1980-07-28 | 1983-12-27 | Ciba-Geigy Corporation | Membrane modified hydrogels |
| US4397907A (en) * | 1981-06-22 | 1983-08-09 | Hughes Aircraft Company | Multi-purpose air permeable composites |
| EP0072046B1 (de) | 1981-07-24 | 1986-01-15 | FISONS plc | Inhalierbare Arzneimittel, Verfahren zu deren Herstellung und pharmazeutische Formulierungen diese enthaltend |
| US5260306A (en) * | 1981-07-24 | 1993-11-09 | Fisons Plc | Inhalation pharmaceuticals |
| GB2105189B (en) | 1981-07-24 | 1985-03-20 | Fisons Plc | Inhalation drugs |
| CH656077A5 (de) * | 1982-01-29 | 1986-06-13 | Glatt Maschinen & Apparatebau | Verfahren zum ueberziehen von teilchen, insbesondere arzneimittel-teilchen, und vorrichtung zur durchfuehrung des verfahrens. |
| JPS59163313A (ja) | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| US4486435A (en) | 1983-05-16 | 1984-12-04 | Basf Wyandotte Corporation | Spray-dried vitamin powders using hydrophobic silica |
| US4582731A (en) * | 1983-09-01 | 1986-04-15 | Battelle Memorial Institute | Supercritical fluid molecular spray film deposition and powder formation |
| US4514574A (en) * | 1984-01-09 | 1985-04-30 | The Dow Chemical Company | Process for separating isomeric mixtures |
| US4568559A (en) * | 1984-02-06 | 1986-02-04 | Biotek, Inc. | Composite core coated microparticles and process of preparing same |
| US4624848A (en) | 1984-05-10 | 1986-11-25 | Ciba-Geigy Corporation | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
| US4749576A (en) * | 1984-05-10 | 1988-06-07 | Ciba-Geigy Corporation | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| WO1988001165A1 (en) * | 1986-08-11 | 1988-02-25 | Innovata Biomed Limited | Pharmaceutical formulations comprising microcapsules |
| US4760093A (en) | 1986-10-21 | 1988-07-26 | American Home Products Corporation (Del.) | Spray dried acetaminophen |
| JP2562624B2 (ja) * | 1986-11-07 | 1996-12-11 | 昭和電工株式会社 | 水溶性マイクロカプセルおよび液体洗剤組成物 |
| NZ222907A (en) | 1986-12-16 | 1990-08-28 | Novo Industri As | Preparation for intranasal administration containing a phospholipid absorption enhancing system |
| US4784878A (en) * | 1987-04-06 | 1988-11-15 | Damrow Company, Inc. | Spray drying method and apparatus for concurrent particle coating |
| SE8701479L (sv) | 1987-04-09 | 1988-10-10 | Carbomatrix Ab | Metod foer inneslutning av biologiskt verksamma preparat samt anvaendning daerav |
| GB8712176D0 (en) | 1987-05-22 | 1987-06-24 | Cosmas Damian Ltd | Drug delivery system |
| US4835187A (en) | 1987-06-15 | 1989-05-30 | American Home Products Corporation | Spray dried ibuprofen |
| US5219575A (en) * | 1987-06-26 | 1993-06-15 | Duphar International Research B.V. | Compositions with controlled zero-order delivery rate and method of preparing these compositions |
| ES2043640T3 (es) * | 1987-12-21 | 1994-01-01 | Union Carbide Corp | Fluidos supercriticos como diluyentes en la aplicacion por rociada liquida de revestimientos. |
| DE3744329A1 (de) | 1987-12-28 | 1989-07-06 | Schwarz Pharma Gmbh | Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung |
| JPH01176437A (ja) | 1987-12-29 | 1989-07-12 | Ono Pharmaceut Co Ltd | 有機物質の微粒化方法 |
| US4919853A (en) * | 1988-01-21 | 1990-04-24 | The United States Of America As Represented By The United States Department Of Energy | Apparatus and method for spraying liquid materials |
| ATE98094T1 (de) | 1988-06-03 | 1993-12-15 | Niro Sterner Inc | Spruehtrocknungsverfahren und vorrichtung zum gleichzeitigen beschichten von teilchen. |
| US5066522A (en) * | 1988-07-14 | 1991-11-19 | Union Carbide Chemicals And Plastics Technology Corporation | Supercritical fluids as diluents in liquid spray applications of adhesives |
| EP0360340A1 (de) | 1988-09-19 | 1990-03-28 | Akzo N.V. | Peptidenthaltende Zubereitung zur intranasalen Verabreichung |
| EP0437451B1 (de) | 1988-10-05 | 1993-06-09 | The Upjohn Company | Feinverteiltes feste kristalline pulver durch niederschlag in einem anti-lösungsmittel |
| US4999189A (en) * | 1988-11-14 | 1991-03-12 | Schering Corporation | Sustained release oral suspensions |
| GB8903593D0 (en) | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| US5009367A (en) * | 1989-03-22 | 1991-04-23 | Union Carbide Chemicals And Plastics Technology Corporation | Methods and apparatus for obtaining wider sprays when spraying liquids by airless techniques |
| US5232707A (en) * | 1989-07-10 | 1993-08-03 | Syntex (U.S.A.) Inc. | Solvent extraction process |
| US5238920A (en) * | 1989-08-22 | 1993-08-24 | Abbott Laboratories | Pulmonary surfactant protein fragments |
| US5178878A (en) * | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
| GB9001635D0 (en) * | 1990-01-24 | 1990-03-21 | Ganderton David | Aerosol carriers |
| US5376386A (en) | 1990-01-24 | 1994-12-27 | British Technology Group Limited | Aerosol carriers |
| US5000888A (en) * | 1990-05-23 | 1991-03-19 | Basf Corporation | Process for spray drying riboflavin to produce a granulate product having low binder content |
| CA2044706C (en) | 1990-06-15 | 2003-02-25 | Michael Midler Jr. | Crystallization method to improve crystal structure and size |
| GB9017155D0 (en) * | 1990-08-03 | 1990-09-19 | Ici Plc | Spray drying |
| JP3080983B2 (ja) * | 1990-11-21 | 2000-08-28 | 東芝タンガロイ株式会社 | 傾斜組成組織の硬質焼結合金及びその製造方法 |
| DE4118230A1 (de) * | 1990-12-20 | 1992-06-25 | Bayer Ag | Verfahren zur isolierung von polymeren aus ihren loesungsmitteln mit kohlendioxid-haltigen fluessigkeiten |
| DE4041563A1 (de) | 1990-12-22 | 1992-06-25 | Sanol Arznei Schwarz Gmbh | Verfahren zur herstellung wirkstoffhaltiger mikropartikel aus hydrolytisch abbaubaren polymeren |
| US5993805A (en) * | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
| GB9107628D0 (en) | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
| DE4117751A1 (de) * | 1991-05-30 | 1992-12-03 | Bayer Ag | Verfahren zur isolierung von polycarbonaten |
| GB9116610D0 (en) | 1991-08-01 | 1991-09-18 | Danbiosyst Uk | Preparation of microparticles |
| US5269980A (en) | 1991-08-05 | 1993-12-14 | Northeastern University | Production of polymer particles in powder form using an atomization technique |
| EP0535937B2 (de) * | 1991-10-01 | 2008-05-21 | Takeda Chemical Industries, Ltd. | Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe |
| US6063910A (en) | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
| DE69306755T2 (de) * | 1992-01-21 | 1997-04-10 | Stanford Res Inst Int | Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln |
| US5639441A (en) | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
| WO1993025198A1 (fr) | 1992-06-12 | 1993-12-23 | Teijin Limited | Poudre ultra-fine pour inhalation et production de cette poudre |
| AU4198793A (en) * | 1992-07-24 | 1994-01-27 | Takeda Chemical Industries Ltd. | Microparticle preparation and production thereof |
| EP0669858A4 (de) * | 1992-11-02 | 1997-07-16 | Ferro Corp | Verfahren zur herstellung beschichteter materialien. |
| AU660852B2 (en) * | 1992-11-25 | 1995-07-06 | Elan Pharma International Limited | Method of grinding pharmaceutical substances |
| EP0670716B1 (de) * | 1992-11-30 | 2003-03-26 | Kv Pharmaceutical Company | Geschmacksmaskierte pharmazeutische substanzen |
| GB9226474D0 (en) | 1992-12-18 | 1993-02-10 | Ici Plc | Production of particulate materials |
| US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| US5916596A (en) | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| IL105658A (en) | 1993-05-11 | 1995-10-31 | Ultrasonic Dryer Ltd | Spray drying system |
| US5554382A (en) * | 1993-05-28 | 1996-09-10 | Aphios Corporation | Methods and apparatus for making liposomes |
| IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| GB9313642D0 (en) | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| KR960011238B1 (ko) * | 1993-07-05 | 1996-08-21 | 주식회사 코오롱 | 산에서 불안정한 화합물의 경구 제형 및 그 제조방법 |
| PL314294A1 (en) * | 1993-11-08 | 1996-09-02 | Gillette Co | Method of producing particles using a hypercritical fluid, aerogel particles obtained thereby and antiperspirants containing such particles |
| IT1265473B1 (it) | 1993-12-30 | 1996-11-22 | Otefal Srl | Procedimento per la produzione di polveri a granulometria controllata e prodotto in polvere cosi' ottenuto |
| US5595761A (en) * | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
| US5635210A (en) * | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
| DE69502179D1 (de) * | 1994-02-09 | 1998-05-28 | Kinerton Ltd | Verfahren zur trocknung eines materials aus einer lösung |
| SI9400079B (sl) | 1994-02-15 | 2003-02-28 | Dr. Weidner Eckhard, Dipl. Ing. | Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom |
| US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| JPH081882A (ja) | 1994-06-20 | 1996-01-09 | Chisso Corp | ポリオレフィン系樹脂製積層フィルム |
| JP3883588B2 (ja) | 1994-06-22 | 2007-02-21 | 大日本印刷株式会社 | 化粧材 |
| JP3175482B2 (ja) | 1994-06-23 | 2001-06-11 | 凸版印刷株式会社 | 化粧シート及びその製造方法 |
| JP3093103B2 (ja) | 1994-06-24 | 2000-10-03 | 住友ベークライト株式会社 | 多層フィルム |
| GB9413202D0 (en) * | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| US5499848A (en) | 1994-09-26 | 1996-03-19 | Bundy Corporation | Connection verifier for a quick connector coupling |
| US6117455A (en) | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
| US5716558A (en) * | 1994-11-14 | 1998-02-10 | Union Carbide Chemicals & Plastics Technology Corporation | Method for producing coating powders catalysts and drier water-borne coatings by spraying compositions with compressed fluids |
| MX9504934A (es) * | 1994-12-12 | 1997-01-31 | Morton Int Inc | Revestimientos en polvo de pelicula delgada lisa. |
| US5639475A (en) * | 1995-02-03 | 1997-06-17 | Eurand America, Incorporated | Effervescent microcapsules |
| US5510118A (en) * | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US6258341B1 (en) * | 1995-04-14 | 2001-07-10 | Inhale Therapeutic Systems, Inc. | Stable glassy state powder formulations |
| US5495681A (en) | 1995-05-24 | 1996-03-05 | Paradis; Andr´E | Pivotable panel for clothes dryer drum |
| US5667806A (en) * | 1995-06-07 | 1997-09-16 | Emisphere Technologies, Inc. | Spray drying method and apparatus |
| US5607697A (en) * | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
| JP3541090B2 (ja) * | 1995-09-08 | 2004-07-07 | 三洋電機株式会社 | アルカリ蓄電池用正極活物質及びその製造方法 |
| CA2234957C (en) | 1995-10-17 | 2006-12-19 | Inge B. Henriksen | Insoluble drug delivery |
| US5807578A (en) * | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
| US5874029A (en) * | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
| WO1997031691A1 (en) * | 1996-03-01 | 1997-09-04 | The University Of Kansas | Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents |
| DE19617487A1 (de) * | 1996-05-02 | 1997-11-06 | Merck Patent Gmbh | Geschmacksverbesserung von Arzneimittelwirkstoffen |
| ES2140998B1 (es) * | 1996-05-13 | 2000-10-16 | Univ Sevilla | Procedimiento de atomizacion de liquidos. |
| US6197835B1 (en) * | 1996-05-13 | 2001-03-06 | Universidad De Sevilla | Device and method for creating spherical particles of uniform size |
| US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US5855913A (en) * | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| JP4036233B2 (ja) | 1996-08-09 | 2008-01-23 | ヤマハ株式会社 | 楽音発生装置および楽音発生方法、並びに該方法に係るプログラムを記憶した記憶媒体 |
| US6017310A (en) * | 1996-09-07 | 2000-01-25 | Andaris Limited | Use of hollow microcapsules |
| AU4219897A (en) * | 1996-09-18 | 1998-04-14 | Daiso Co. Ltd. | Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers |
| FR2753639B1 (fr) * | 1996-09-25 | 1998-12-11 | Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede | |
| GB9622173D0 (en) | 1996-10-24 | 1996-12-18 | Glaxo Group Ltd | Particulate Products |
| US20030203036A1 (en) * | 2000-03-17 | 2003-10-30 | Gordon Marc S. | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
| JP2001507701A (ja) * | 1996-12-31 | 2001-06-12 | インヘイル・セラピューティック・システムズ・インコーポレーテッド | 親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物 |
| GB9703673D0 (en) | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
| US6051257A (en) * | 1997-02-24 | 2000-04-18 | Superior Micropowders, Llc | Powder batch of pharmaceutically-active particles and methods for making same |
| US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| GB9800936D0 (en) * | 1997-05-10 | 1998-03-11 | Univ Nottingham | Biofunctional polymers |
| WO1998053940A1 (de) | 1997-05-28 | 1998-12-03 | Siemens Aktiengesellschaft | Metall-keramik-gradientenwerkstoff, erzeugnis daraus und verfahren zur herstellung eines metall-keramik-gradientenwerkstoffes |
| US6565885B1 (en) * | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| EP1027036A2 (de) | 1997-10-03 | 2000-08-16 | ELAN CORPORATION, Plc | Geschmacksmaskierte formulierungen |
| US5904937A (en) | 1997-10-03 | 1999-05-18 | Fmc Corporation | Taste masked pharmaceutical compositions |
| DK1028820T3 (da) | 1997-10-15 | 2010-04-26 | Univ South Florida | Coating til partikelmateriale ved hjælp af superkritisk fluid |
| EP1293259A3 (de) | 1997-12-17 | 2004-01-07 | Universidad De Sevilla | Vorrichtung und Verfahren zur Erzeugung von Aerosolen zur Arzneimittelverabreichung |
| JPH11197494A (ja) * | 1998-01-13 | 1999-07-27 | Kenji Mishima | 超臨界流体を用いた微小粒子コーティング |
| GB9804379D0 (en) | 1998-03-02 | 1998-04-22 | Bradford Particle Design Ltd | Method of particle formation |
| SE9801288D0 (sv) | 1998-04-14 | 1998-04-14 | Astra Ab | Vaccine delivery system and metod of production |
| GB9810559D0 (en) | 1998-05-15 | 1998-07-15 | Bradford Particle Design Ltd | Method and apparatus for particle formation |
| US6387410B1 (en) * | 1998-09-10 | 2002-05-14 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| SE9804001D0 (sv) | 1998-11-23 | 1998-11-23 | Astra Ab | New process |
| SE9804003D0 (sv) | 1998-11-23 | 1998-11-23 | Astra Ab | A method of producing drug particles |
| EP1133282A4 (de) | 1998-11-25 | 2006-03-29 | Cima Labs Inc | Geschmacksmaskierendes überzugssystem mit schneller freisetzung |
| GB9825883D0 (en) | 1998-11-27 | 1999-01-20 | Aea Technology Plc | Formation of monodisperse particles |
| ATE404178T1 (de) * | 1999-02-10 | 2008-08-15 | Pfizer Prod Inc | Vorrichtung mit matrixgesteuerter wirkstofffreisetzung |
| SE9901667D0 (sv) | 1999-05-07 | 1999-05-07 | Astra Ab | Method and device for forming particles |
| GB9915975D0 (en) * | 1999-07-07 | 1999-09-08 | Bradford Particle Design Ltd | Method for the formation of particles |
| FR2795962B1 (fr) | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
| US20020081266A1 (en) * | 1999-08-20 | 2002-06-27 | Norton Healthcare Ltd. | Spray dried powders for pulmonary or nasal administration |
| GB9920558D0 (en) * | 1999-08-31 | 1999-11-03 | Bradford Particle Design Ltd | Methods for particle formation and their products |
| AU2729101A (en) * | 1999-12-21 | 2001-07-03 | Rxkinetix, Inc. | Particulate drug-containing products and method of manufacture |
| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| US6551617B1 (en) * | 2000-04-20 | 2003-04-22 | Bristol-Myers Squibb Company | Taste masking coating composition |
| US6316029B1 (en) * | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
| US6620351B2 (en) * | 2000-05-24 | 2003-09-16 | Auburn University | Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer |
| US6656492B2 (en) | 2000-06-30 | 2003-12-02 | Yamanouchi Pharmaceutical Co., Ltd. | Quick disintegrating tablet in buccal cavity and manufacturing method thereof |
| WO2002009669A2 (en) * | 2000-08-01 | 2002-02-07 | Inhale Therapeutic Systems, Inc. | Apparatus and process to produce particles having a narrow size distribution and particles made thereby |
| FR2815540B1 (fr) | 2000-10-19 | 2005-06-10 | Separex Sa | Procede de fabrication de tres fines particules constituees d'un principe insere dans une molecule hote |
| GB0027357D0 (en) * | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
| GB0102075D0 (en) | 2001-01-26 | 2001-03-14 | Astrazeneca Ab | Process |
| GB0117696D0 (en) * | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
| TW586963B (en) | 2001-07-20 | 2004-05-11 | Nektar Therapeutics Uk Ltd | Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus |
| EP1992335A1 (de) * | 2001-11-01 | 2008-11-19 | Nektar Therapeutics | Sprühtrocknungsverfahren und Zusammensetzungen dafür |
| MXPA04008737A (es) * | 2002-03-08 | 2005-07-13 | M S Ind Swift Ltd | Complejos que se disuelven rapidamente, comprensibles directamente, insipidos, y formulaciones farmaceuticas de los mismos. |
| KR20060015587A (ko) | 2003-05-08 | 2006-02-17 | 넥타 쎄라퓨틱스 유케이 리미티드 | 미립물 |
| JP4187739B2 (ja) | 2005-10-17 | 2008-11-26 | 電気化学工業株式会社 | アルミニウム合金−炭化珪素窒化珪素質複合体 |
| JP5057166B2 (ja) | 2008-10-30 | 2012-10-24 | アイシン・エィ・ダブリュ株式会社 | 安全運転評価システム及び安全運転評価プログラム |
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2000
- 2000-11-09 GB GB0027357A patent/GB0027357D0/en not_active Ceased
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2001
- 2001-11-01 AU AU2002210765A patent/AU2002210765B9/en not_active Expired
- 2001-11-01 US US10/004,522 patent/US7115280B2/en not_active Expired - Lifetime
- 2001-11-01 AT AT01978670T patent/ATE382336T1/de not_active IP Right Cessation
- 2001-11-01 GB GB0126193A patent/GB2371501B/en not_active Expired - Fee Related
- 2001-11-01 CA CA2426247A patent/CA2426247C/en not_active Expired - Lifetime
- 2001-11-01 MX MXPA03003846A patent/MXPA03003846A/es active IP Right Grant
- 2001-11-01 WO PCT/GB2001/004873 patent/WO2002038127A2/en not_active Ceased
- 2001-11-01 DE DE60132230T patent/DE60132230T2/de not_active Revoked
- 2001-11-01 GB GB0217667A patent/GB2380147A/en not_active Withdrawn
- 2001-11-01 JP JP2002540717A patent/JP4880863B2/ja not_active Expired - Lifetime
- 2001-11-01 AU AU1076502A patent/AU1076502A/xx active Pending
- 2001-11-01 KR KR1020037006171A patent/KR100822098B1/ko not_active Expired - Fee Related
- 2001-11-01 EP EP01978670A patent/EP1331928B1/de not_active Revoked
- 2001-11-01 ES ES01978670T patent/ES2299519T3/es not_active Expired - Lifetime
- 2001-11-05 TW TW90127442A patent/TWI241198B/zh not_active IP Right Cessation
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2006
- 2006-07-17 US US11/458,008 patent/US9120031B2/en active Active
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2015
- 2015-08-31 US US14/841,325 patent/US20150366241A1/en not_active Abandoned
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- 2017-07-18 US US15/653,059 patent/US10798955B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002210765B9 (en) | 2006-06-15 |
| US7115280B2 (en) | 2006-10-03 |
| GB0217667D0 (en) | 2002-09-11 |
| WO2002038127A2 (en) | 2002-05-16 |
| US20100222220A1 (en) | 2010-09-02 |
| KR100822098B1 (ko) | 2008-04-15 |
| CA2426247A1 (en) | 2002-05-16 |
| MXPA03003846A (es) | 2004-10-28 |
| US20150366241A1 (en) | 2015-12-24 |
| GB0027357D0 (en) | 2000-12-27 |
| GB2371501B (en) | 2003-05-14 |
| CA2426247C (en) | 2011-03-08 |
| KR20030051781A (ko) | 2003-06-25 |
| US10798955B2 (en) | 2020-10-13 |
| US20020114844A1 (en) | 2002-08-22 |
| WO2002038127A3 (en) | 2003-01-09 |
| DE60132230D1 (de) | 2008-02-14 |
| GB2380147A (en) | 2003-04-02 |
| GB2371501A (en) | 2002-07-31 |
| ES2299519T3 (es) | 2008-06-01 |
| AU2002210765B2 (en) | 2006-05-11 |
| EP1331928B1 (de) | 2008-01-02 |
| EP1331928A2 (de) | 2003-08-06 |
| US20170318839A1 (en) | 2017-11-09 |
| JP2004512942A (ja) | 2004-04-30 |
| AU1076502A (en) | 2002-05-21 |
| US9120031B2 (en) | 2015-09-01 |
| JP4880863B2 (ja) | 2012-02-22 |
| GB0126193D0 (en) | 2002-01-02 |
| TWI241198B (en) | 2005-10-11 |
| DE60132230T2 (de) | 2009-01-02 |
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