ATE382349T1 - Antivirale verwendungen von leflunomid produkten - Google Patents
Antivirale verwendungen von leflunomid produktenInfo
- Publication number
- ATE382349T1 ATE382349T1 AT99912426T AT99912426T ATE382349T1 AT E382349 T1 ATE382349 T1 AT E382349T1 AT 99912426 T AT99912426 T AT 99912426T AT 99912426 T AT99912426 T AT 99912426T AT E382349 T1 ATE382349 T1 AT E382349T1
- Authority
- AT
- Austria
- Prior art keywords
- leflunomide
- antiviral uses
- products
- leflunomide products
- antiviral
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- VHOGYURTWQBHIL-UHFFFAOYSA-N leflunomide Chemical compound O1N=CC(C(=O)NC=2C=CC(=CC=2)C(F)(F)F)=C1C VHOGYURTWQBHIL-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000681 leflunomide Drugs 0.000 title abstract 2
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 abstract 2
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 abstract 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 abstract 1
- 229940045145 uridine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7755298P | 1998-03-11 | 1998-03-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE382349T1 true ATE382349T1 (de) | 2008-01-15 |
Family
ID=22138741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99912426T ATE382349T1 (de) | 1998-03-11 | 1999-03-11 | Antivirale verwendungen von leflunomid produkten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1169036B1 (de) |
| JP (1) | JP4581137B2 (de) |
| AT (1) | ATE382349T1 (de) |
| AU (1) | AU3080299A (de) |
| DE (1) | DE69937904T2 (de) |
| HK (1) | HK1045251A1 (de) |
| WO (1) | WO1999045908A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003526639A (ja) * | 2000-02-28 | 2003-09-09 | バイエル アクチェンゲゼルシャフト | ウイルス疾患のための薬物 |
| JP2005104852A (ja) * | 2003-09-29 | 2005-04-21 | Kyowa Hakko Kogyo Co Ltd | モービリウィルス感染症の予防または治療用組成物 |
| US20060024376A1 (en) * | 2004-07-30 | 2006-02-02 | The University Of Chicago | Methods and compositions for reducing toxicity associated with leflunomide treatment |
| WO2021164672A1 (zh) * | 2020-02-18 | 2021-08-26 | 华东理工大学 | 抗rna病毒药物及其应用 |
| CA3207366A1 (fr) * | 2021-02-10 | 2022-08-18 | Henry JOSEPH | Composition therapeutique a base de feuilles de neurolaena inhibitrice de la dhodh pour le traitement d'infections par virus a arn |
| FR3119539B1 (fr) * | 2021-02-10 | 2023-12-22 | Phytobokaz | Composition thérapeutique inhibitrice de la DHODH |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES448386A1 (es) * | 1975-06-05 | 1978-04-16 | Hoechst Ag | Procedimiento para la preparacion de anilidas de acido 5-me-til-isoxazol-4-carboxilico. |
| ES2124801T3 (es) * | 1993-01-08 | 1999-02-16 | Hoechst Ag | Empleo de leflunomida para la inhibicion del factor de necrosis de tumores alfa. |
| ES2124800T3 (es) * | 1993-01-08 | 1999-02-16 | Hoechst Ag | Empleo de leflunomida para la inhibicion de interleuquina 1 beta. |
| WO1994024095A1 (en) * | 1993-04-16 | 1994-10-27 | Abbott Laboratories | Immunosuppressive agents |
| US5519042A (en) * | 1994-01-13 | 1996-05-21 | Hoechst Aktiengesellschaft | Method of treating hyperproliferative vascular disease |
| JP4408450B2 (ja) * | 1994-07-01 | 2010-02-03 | ウェルスタット セラピューティクス コーポレイション | 全身性炎症および炎症性肝炎の処置のためのピリミジンヌクレオチド前駆体 |
| DE19711800A1 (de) * | 1997-03-21 | 1998-09-24 | Hoechst Ag | Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung |
-
1999
- 1999-03-11 EP EP99912426A patent/EP1169036B1/de not_active Expired - Lifetime
- 1999-03-11 AT AT99912426T patent/ATE382349T1/de not_active IP Right Cessation
- 1999-03-11 JP JP2000535323A patent/JP4581137B2/ja not_active Expired - Fee Related
- 1999-03-11 AU AU30802/99A patent/AU3080299A/en not_active Abandoned
- 1999-03-11 WO PCT/US1999/005326 patent/WO1999045908A2/en not_active Ceased
- 1999-03-11 HK HK02105067.5A patent/HK1045251A1/zh unknown
- 1999-03-11 DE DE69937904T patent/DE69937904T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4581137B2 (ja) | 2010-11-17 |
| EP1169036B1 (de) | 2008-01-02 |
| AU3080299A (en) | 1999-09-27 |
| WO1999045908A3 (en) | 2000-01-20 |
| JP2003523309A (ja) | 2003-08-05 |
| HK1045251A1 (zh) | 2002-11-22 |
| EP1169036A2 (de) | 2002-01-09 |
| DE69937904D1 (de) | 2008-02-14 |
| DE69937904T2 (de) | 2009-01-02 |
| WO1999045908A2 (en) | 1999-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |