ATE382628T1 - Tetrahydrobenzfluorenderivate - Google Patents

Tetrahydrobenzfluorenderivate

Info

Publication number
ATE382628T1
ATE382628T1 AT02793020T AT02793020T ATE382628T1 AT E382628 T1 ATE382628 T1 AT E382628T1 AT 02793020 T AT02793020 T AT 02793020T AT 02793020 T AT02793020 T AT 02793020T AT E382628 T1 ATE382628 T1 AT E382628T1
Authority
AT
Austria
Prior art keywords
tetrahydrobenez
fluorene derivatives
fluorene
derivatives
tetrahydrobenez fluorene
Prior art date
Application number
AT02793020T
Other languages
English (en)
Inventor
Hubert Jan Jozef Loozen
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Application granted granted Critical
Publication of ATE382628T1 publication Critical patent/ATE382628T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J69/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one atom and expansion of only one ring by one atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
AT02793020T 2001-12-21 2002-12-16 Tetrahydrobenzfluorenderivate ATE382628T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01205206 2001-12-21

Publications (1)

Publication Number Publication Date
ATE382628T1 true ATE382628T1 (de) 2008-01-15

Family

ID=8181558

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02793020T ATE382628T1 (de) 2001-12-21 2002-12-16 Tetrahydrobenzfluorenderivate

Country Status (11)

Country Link
US (2) US7304155B2 (de)
EP (1) EP1458743B1 (de)
JP (1) JP5054882B2 (de)
AR (1) AR038035A1 (de)
AT (1) ATE382628T1 (de)
AU (1) AU2002358715A1 (de)
DE (1) DE60224441T2 (de)
ES (1) ES2298414T3 (de)
PE (1) PE20030697A1 (de)
TW (1) TW200408385A (de)
WO (1) WO2003053994A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200408385A (en) * 2001-12-21 2004-06-01 Akzo Nobel Nv Tetrahydrobenzfluorene derivatives
US9623021B2 (en) 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
EA026578B1 (ru) 2007-01-22 2017-04-28 ДЖиТиЭкс, ИНК. Вещества, связывающие ядерные рецепторы
US9604931B2 (en) 2007-01-22 2017-03-28 Gtx, Inc. Nuclear receptor binding agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147880A (en) * 1991-07-22 1992-09-15 Eli Lilly And Company Benzo[a]fluorene compounds
JP2003528858A (ja) 2000-03-27 2003-09-30 アクゾ・ノベル・エヌ・ベー エストロゲン関連治療用のノンステロイド系四環式化合物
TW200408385A (en) * 2001-12-21 2004-06-01 Akzo Nobel Nv Tetrahydrobenzfluorene derivatives

Also Published As

Publication number Publication date
DE60224441T2 (de) 2008-12-11
EP1458743B1 (de) 2008-01-02
AU2002358715A1 (en) 2003-07-09
US20050119264A1 (en) 2005-06-02
EP1458743A1 (de) 2004-09-22
US7304155B2 (en) 2007-12-04
DE60224441D1 (de) 2008-02-14
PE20030697A1 (es) 2003-08-18
AR038035A1 (es) 2004-12-22
JP5054882B2 (ja) 2012-10-24
WO2003053994A1 (en) 2003-07-03
ES2298414T3 (es) 2008-05-16
JP2005518387A (ja) 2005-06-23
US20080058361A1 (en) 2008-03-06
TW200408385A (en) 2004-06-01
US7655653B2 (en) 2010-02-02

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties