ATE383335T1 - 3-amino-pyrrolidine als inhibitoren der monoamin- wiederaufnahme - Google Patents
3-amino-pyrrolidine als inhibitoren der monoamin- wiederaufnahmeInfo
- Publication number
- ATE383335T1 ATE383335T1 AT04750759T AT04750759T ATE383335T1 AT E383335 T1 ATE383335 T1 AT E383335T1 AT 04750759 T AT04750759 T AT 04750759T AT 04750759 T AT04750759 T AT 04750759T AT E383335 T1 ATE383335 T1 AT E383335T1
- Authority
- AT
- Austria
- Prior art keywords
- reuppost
- monoamine
- pyrrolidine
- inhibitors
- amino
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- NGXSWUFDCSEIOO-UHFFFAOYSA-N pyrrolidin-3-amine Chemical compound NC1CCNC1 NGXSWUFDCSEIOO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0313463A GB0313463D0 (en) | 2003-06-11 | 2003-06-11 | Inhibitors on monoamine uptake |
| US51086703P | 2003-10-14 | 2003-10-14 | |
| US52445003P | 2003-11-24 | 2003-11-24 | |
| US52478103P | 2003-11-25 | 2003-11-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE383335T1 true ATE383335T1 (de) | 2008-01-15 |
Family
ID=33556507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04750759T ATE383335T1 (de) | 2003-06-11 | 2004-05-11 | 3-amino-pyrrolidine als inhibitoren der monoamin- wiederaufnahme |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7619096B2 (de) |
| EP (1) | EP1638934B1 (de) |
| AR (1) | AR044570A1 (de) |
| AT (1) | ATE383335T1 (de) |
| DE (1) | DE602004011221T2 (de) |
| ES (1) | ES2298782T3 (de) |
| PE (1) | PE20050160A1 (de) |
| SV (1) | SV2005001805A (de) |
| TW (1) | TW200508195A (de) |
| WO (1) | WO2005000811A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1735302B1 (de) | 2004-02-27 | 2010-06-16 | Eli Lilly And Company | 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme |
| US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
| EP1756050A1 (de) | 2004-06-01 | 2007-02-28 | Eli Lilly And Company | Aminomethylazacyclusderivate als inhibitoren der monoaminaufnahme |
| DK1848430T3 (da) | 2004-12-31 | 2017-11-06 | Dr Reddys Laboratories Ltd | Nye benzylamin-derivativer som cetp-inhibitors |
| US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| TWI410406B (zh) * | 2005-05-13 | 2013-10-01 | Otsuka Pharma Co Ltd | 吡咯烷化合物 |
| US20090215857A1 (en) * | 2005-09-13 | 2009-08-27 | Pfizer Products Inc. | Therapeutic Pyrrolidines |
| JP5219465B2 (ja) * | 2006-11-10 | 2013-06-26 | 大塚製薬株式会社 | 医薬 |
| GB0701171D0 (en) * | 2007-01-22 | 2007-02-28 | Imp Innovations Ltd | Compositions and uses thereof |
| EP2974724A1 (de) | 2009-02-09 | 2016-01-20 | Sunovion Pharmaceuticals Inc. | Dreifach-pyrrolidin-serotonin-wiederaufnahme-inhibitoren |
| JP5714580B2 (ja) | 2009-07-21 | 2015-05-07 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ３−フェノキシメチルピロリジン化合物 |
| CA2845284C (en) | 2011-08-18 | 2018-03-06 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (cetp) inhibitors |
| JP6140168B2 (ja) | 2011-09-27 | 2017-05-31 | ドクター レディズ ラボラトリーズ リミテッド | アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質（ｃｅｔｐ）インヒビターとしての５−ベンジルアミノメチル−６−アミノピラゾロ［３，４−ｂ］ピリジン誘導体 |
| EP2877483B1 (de) | 2012-07-25 | 2019-05-15 | Bio-rad Laboratories, Inc. | Gezielte abgabe von reagenzien durch gemusterte übertragungsfolien |
| US12084472B2 (en) | 2015-12-18 | 2024-09-10 | Ardelyx, Inc. | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists |
| TWI773657B (zh) | 2015-12-18 | 2022-08-11 | 美商亞德利克斯公司 | 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002519321A (ja) * | 1998-06-30 | 2002-07-02 | イーライ・リリー・アンド・カンパニー | セロトニン関連系に効果を有するピロリジン、及び、ピロリン誘導体 |
| CN1332726A (zh) | 1998-11-02 | 2002-01-23 | 卫福有限公司 | 吡咯烷化合物及其药物用途 |
| EP1818326A1 (de) * | 2000-01-20 | 2007-08-15 | Eisai R&D Management Co., Ltd. | Stickstoffhaltige heterocyclische Verbindungen und deren pharmazeutische Zusammensetzungen |
| EP1263729B1 (de) * | 2000-03-06 | 2006-12-20 | Acadia Pharmaceuticals Inc. | Azacyclische verbindungen zur verwendung in der behandlung von mit serotonin verwandten krankheiten |
| EP1430027B1 (de) * | 2001-09-14 | 2010-09-01 | High Point Pharmaceuticals, LLC | Neue aminoazetidin-, aminopyrrolidin- und aminopiperidinderivative |
| KR20050008846A (ko) * | 2002-06-24 | 2005-01-21 | 아카디아 파마슈티칼스 인코포레이티드 | 세로토닌 수용체 제제로서의 ｎ-치환된 피페리딘 유도체 |
| EP1556045B1 (de) * | 2002-10-04 | 2006-08-02 | Ucb, S.A. | 4-aminopiperidin-derivate, verfahren zur herstellung und ihre verwendung als arzneimittel |
| EP1569905A2 (de) * | 2002-12-06 | 2005-09-07 | Eli Lilly And Company | Monoamin-uptake inhibitoren |
-
2004
- 2004-05-11 DE DE602004011221T patent/DE602004011221T2/de not_active Expired - Fee Related
- 2004-05-11 ES ES04750759T patent/ES2298782T3/es not_active Expired - Lifetime
- 2004-05-11 WO PCT/US2004/013004 patent/WO2005000811A1/en not_active Ceased
- 2004-05-11 EP EP04750759A patent/EP1638934B1/de not_active Expired - Lifetime
- 2004-05-11 AT AT04750759T patent/ATE383335T1/de not_active IP Right Cessation
- 2004-05-11 US US10/558,626 patent/US7619096B2/en not_active Expired - Fee Related
- 2004-05-28 PE PE2004000546A patent/PE20050160A1/es not_active Application Discontinuation
- 2004-05-28 AR ARP040101856A patent/AR044570A1/es unknown
- 2004-05-31 TW TW093115543A patent/TW200508195A/zh unknown
- 2004-06-11 SV SV2004001805A patent/SV2005001805A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20060270713A1 (en) | 2006-11-30 |
| US7619096B2 (en) | 2009-11-17 |
| DE602004011221T2 (de) | 2009-01-02 |
| TW200508195A (en) | 2005-03-01 |
| PE20050160A1 (es) | 2005-03-26 |
| EP1638934B1 (de) | 2008-01-09 |
| DE602004011221D1 (de) | 2008-02-21 |
| WO2005000811A1 (en) | 2005-01-06 |
| ES2298782T3 (es) | 2008-05-16 |
| AR044570A1 (es) | 2005-09-21 |
| SV2005001805A (es) | 2005-11-04 |
| EP1638934A1 (de) | 2006-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |