ATE383341T1 - Substituierte caprolactam carbonate und ether sowie deren verwendung als anti-tumor wirkstoffe - Google Patents

Substituierte caprolactam carbonate und ether sowie deren verwendung als anti-tumor wirkstoffe

Info

Publication number: ATE383341T1
Authority: AT; Austria
Prior art keywords: carbonate; ether; active ingredients; tumor active; compounds
Prior art date: 2000-05-11

Application number

AT01975824T

Other languages

English (en)

Inventor

Frederick Kinder

Richard Versace

Kenneth Bair

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-11

Filing date

2001-05-09

Publication date

2008-01-15

2001-05-09 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2008-01-15 Application granted granted Critical

2008-01-15 Publication of ATE383341T1 publication Critical patent/ATE383341T1/de

Links

BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 title abstract 2
JBKVHLHDHHXQEQ-UHFFFAOYSA-N epsilon-caprolactam Chemical class O=C1CCCCCN1 JBKVHLHDHHXQEQ-UHFFFAOYSA-N 0.000 title 2
239000004480 active ingredient Substances 0.000 title 1
230000000259 anti-tumor effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
206010028980 Neoplasm Diseases 0.000 abstract 1
150000002170 ethers Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

AT01975824T 2000-05-11 2001-05-09 Substituierte caprolactam carbonate und ether sowie deren verwendung als anti-tumor wirkstoffe ATE383341T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US56866700A	2000-05-11	2000-05-11

Publications (1)

Publication Number	Publication Date
ATE383341T1 true ATE383341T1 (de)	2008-01-15

Family

ID=24272224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01975824T ATE383341T1 (de)	2000-05-11	2001-05-09	Substituierte caprolactam carbonate und ether sowie deren verwendung als anti-tumor wirkstoffe

Country Status (11)

Country	Link
EP (1)	EP1282604B1 (de)
JP (1)	JP2003532711A (de)
CN (1)	CN1191237C (de)
AT (1)	ATE383341T1 (de)
AU (1)	AU2001295206A1 (de)
BR (1)	BR0110641A (de)
CA (1)	CA2405892C (de)
DE (1)	DE60132324T2 (de)
ES (1)	ES2299515T3 (de)
PT (1)	PT1282604E (de)
WO (1)	WO2001085697A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7378410B2 (en)	2003-07-25	2008-05-27	Novartis Ag	Substituted lactams and their use as anti-cancer agents
US7153846B2 (en)	2003-10-24	2006-12-26	Sanofi-Aventis Deutschland Gmbh	Bengamide derivatives, process for preparing them, and their use
DE10349669B3 (de) *	2003-10-24	2005-05-25	Aventis Pharma Deutschland Gmbh	Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2878525B1 (fr)	2004-11-29	2007-02-23	Aventis Pharma Sa	Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2878528B1 (fr) *	2004-11-29	2008-05-16	Aventis Pharma Sa	2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2901554B1 (fr) *	2006-05-24	2011-04-01	Sanofi Aventis	2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation
FR2901556A1 (fr)	2006-05-24	2007-11-30	Sanofi Aventis Sa	Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
FR2901555A1 (fr)	2006-05-24	2007-11-30	Sanofi Aventis Sa	2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4831135A (en) *	1986-06-18	1989-05-16	The Regents Of The University Of California	Bengamide anthelmintics
GB9411841D0 (en) *	1994-06-14	1994-08-03	Pharma Mar Sa	New antitumoral compounds from jaspis sponge
CO5140099A1 (es) *	1998-11-17	2002-03-22	Novartis Ag	Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores

2001
- 2001-05-09 AT AT01975824T patent/ATE383341T1/de not_active IP Right Cessation
- 2001-05-09 ES ES01975824T patent/ES2299515T3/es not_active Expired - Lifetime
- 2001-05-09 BR BR0110641-4A patent/BR0110641A/pt not_active Application Discontinuation
- 2001-05-09 AU AU2001295206A patent/AU2001295206A1/en not_active Abandoned
- 2001-05-09 WO PCT/EP2001/005263 patent/WO2001085697A1/en not_active Ceased
- 2001-05-09 EP EP01975824A patent/EP1282604B1/de not_active Expired - Lifetime
- 2001-05-09 PT PT01975824T patent/PT1282604E/pt unknown
- 2001-05-09 DE DE60132324T patent/DE60132324T2/de not_active Expired - Lifetime
- 2001-05-09 JP JP2001582298A patent/JP2003532711A/ja active Pending
- 2001-05-09 CN CNB018093078A patent/CN1191237C/zh not_active Expired - Fee Related
- 2001-05-09 CA CA002405892A patent/CA2405892C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
BR0110641A (pt)	2003-03-18
AU2001295206A1 (en)	2001-11-20
CA2405892A1 (en)	2001-11-15
DE60132324D1 (de)	2008-02-21
PT1282604E (pt)	2008-04-11
ES2299515T3 (es)	2008-06-01
DE60132324T2 (de)	2008-12-24
EP1282604B1 (de)	2008-01-09
CA2405892C (en)	2009-07-07
EP1282604A1 (de)	2003-02-12
CN1191237C (zh)	2005-03-02
WO2001085697A1 (en)	2001-11-15
CN1429213A (zh)	2003-07-09
JP2003532711A (ja)	2003-11-05

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Legal Events

Date

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Title

Description

2008-08-15

UEP

Publication of translation of european patent specification

Ref document number: 1282604

Country of ref document: EP

2012-02-15

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Ceased due to non-payment of the annual fee