ATE383856T1 - (4-hydroxyphenyl)-1h-indol-3-carbaldehydoxim- derivative als östrogenagentien - Google Patents

(4-hydroxyphenyl)-1h-indol-3-carbaldehydoxim- derivative als östrogenagentien

Info

Publication number: ATE383856T1
Authority: AT; Austria
Prior art keywords: sub; carbaldehydoxime; indole; hydroxyphenyl; derivatives
Prior art date: 2003-08-12

Application number

AT04780574T

Other languages

English (en)

Inventor

Richard Eric Mewshaw

Stephen Bowen

Eric Manas

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-12

Filing date

2004-08-10

Publication date

2008-02-15

2004-08-10 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-02-15 Application granted granted Critical

2008-02-15 Publication of ATE383856T1 publication Critical patent/ATE383856T1/de

Links

PUZSIQXETQCQII-UHFFFAOYSA-N 4-[3-(hydroxyiminomethyl)indol-1-yl]phenol Chemical class C12=CC=CC=C2C(C=NO)=CN1C1=CC=C(O)C=C1 PUZSIQXETQCQII-UHFFFAOYSA-N 0.000 title 1
239000003795 chemical substances by application Substances 0.000 title 1
229940011871 estrogen Drugs 0.000 title 1
239000000262 estrogen Substances 0.000 title 1
239000002834 estrogen receptor modulator Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Dermatology (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Psychiatry (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Pregnancy & Childbirth (AREA)
Vascular Medicine (AREA)

AT04780574T 2003-08-12 2004-08-10 (4-hydroxyphenyl)-1h-indol-3-carbaldehydoxim- derivative als östrogenagentien ATE383856T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US49436503P	2003-08-12	2003-08-12
US10/914,747 US7250440B2 (en)	2003-08-12	2004-08-09	(Hydroxyphenyl)-1H-indole-3-carbaldehyde oxime derivatives as estrogenic agents

Publications (1)

Publication Number	Publication Date
ATE383856T1 true ATE383856T1 (de)	2008-02-15

Family

ID=34221360

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04780574T ATE383856T1 (de)	2003-08-12	2004-08-10	(4-hydroxyphenyl)-1h-indol-3-carbaldehydoxim- derivative als östrogenagentien

Country Status (13)

Country	Link
US (2)	US7250440B2 (de)
EP (1)	EP1653947B1 (de)
JP (1)	JP2007502277A (de)
AT (1)	ATE383856T1 (de)
AU (1)	AU2004266603A1 (de)
BR (1)	BRPI0413523A (de)
CA (1)	CA2535341A1 (de)
DE (1)	DE602004011358T2 (de)
DK (1)	DK1653947T3 (de)
ES (1)	ES2298823T3 (de)
MX (1)	MXPA06001592A (de)
PL (1)	PL1653947T3 (de)
WO (1)	WO2005018636A1 (de)

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2004
- 2004-08-09 US US10/914,747 patent/US7250440B2/en not_active Expired - Fee Related
- 2004-08-10 EP EP04780574A patent/EP1653947B1/de not_active Expired - Lifetime
- 2004-08-10 PL PL04780574T patent/PL1653947T3/pl unknown
- 2004-08-10 ES ES04780574T patent/ES2298823T3/es not_active Expired - Lifetime
- 2004-08-10 DK DK04780574T patent/DK1653947T3/da active
- 2004-08-10 AU AU2004266603A patent/AU2004266603A1/en not_active Abandoned
- 2004-08-10 WO PCT/US2004/025764 patent/WO2005018636A1/en not_active Ceased
- 2004-08-10 JP JP2006523281A patent/JP2007502277A/ja active Pending
- 2004-08-10 DE DE602004011358T patent/DE602004011358T2/de not_active Expired - Fee Related
- 2004-08-10 CA CA002535341A patent/CA2535341A1/en not_active Abandoned
- 2004-08-10 AT AT04780574T patent/ATE383856T1/de not_active IP Right Cessation
- 2004-08-10 BR BRPI0413523-7A patent/BRPI0413523A/pt not_active IP Right Cessation
- 2004-08-10 MX MXPA06001592A patent/MXPA06001592A/es active IP Right Grant
2007
- 2007-06-20 US US11/765,548 patent/US20070249703A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1653947B1 (de)	2008-01-16
US20070249703A1 (en)	2007-10-25
WO2005018636A1 (en)	2005-03-03
DE602004011358D1 (de)	2008-03-06
JP2007502277A (ja)	2007-02-08
DE602004011358T2 (de)	2009-01-15
ES2298823T3 (es)	2008-05-16
CA2535341A1 (en)	2005-03-03
US7250440B2 (en)	2007-07-31
AU2004266603A1 (en)	2005-03-03
DK1653947T3 (da)	2008-04-28
US20050059723A1 (en)	2005-03-17
MXPA06001592A (es)	2006-05-19
BRPI0413523A (pt)	2006-10-10
PL1653947T3 (pl)	2008-05-30
EP1653947A1 (de)	2006-05-10

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2008-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
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