ATE384137T1 - Identifizierung genetischer marker des biologischen alters und des metabolismus - Google Patents
Identifizierung genetischer marker des biologischen alters und des metabolismusInfo
- Publication number
- ATE384137T1 ATE384137T1 AT00952626T AT00952626T ATE384137T1 AT E384137 T1 ATE384137 T1 AT E384137T1 AT 00952626 T AT00952626 T AT 00952626T AT 00952626 T AT00952626 T AT 00952626T AT E384137 T1 ATE384137 T1 AT E384137T1
- Authority
- AT
- Austria
- Prior art keywords
- organ
- tissue
- cell
- gene expression
- subjects
- Prior art date
Links
- 230000002068 genetic effect Effects 0.000 title 1
- 230000004060 metabolic process Effects 0.000 title 1
- 230000014509 gene expression Effects 0.000 abstract 5
- 210000000056 organ Anatomy 0.000 abstract 5
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 230000032683 aging Effects 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 230000008049 biological aging Effects 0.000 abstract 1
- 239000000090 biomarker Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14854099P | 1999-08-12 | 1999-08-12 | |
| US17823200P | 2000-01-26 | 2000-01-26 | |
| US21192300P | 2000-06-16 | 2000-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384137T1 true ATE384137T1 (de) | 2008-02-15 |
Family
ID=27386702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00952626T ATE384137T1 (de) | 1999-08-12 | 2000-08-08 | Identifizierung genetischer marker des biologischen alters und des metabolismus |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6569624B1 (de) |
| EP (1) | EP1200629B1 (de) |
| AT (1) | ATE384137T1 (de) |
| AU (1) | AU782102B2 (de) |
| CA (1) | CA2381777C (de) |
| DE (1) | DE60037817D1 (de) |
| WO (1) | WO2001012851A2 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960439B2 (en) | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US8642284B1 (en) | 1999-12-15 | 2014-02-04 | Massachusetts Institute Of Technology | Methods for identifying agents that alter NAD-dependent deacetylation activity of a SIR2 protein |
| US7452664B2 (en) | 1999-12-15 | 2008-11-18 | Massachusetts Institute Of Technology | Methods for identifying agents which alter histone protein acetylation |
| CA2395466A1 (en) * | 1999-12-23 | 2001-06-28 | The Regents Of The University Of California | Interventions to mimic the effects of calorie restriction |
| US6406853B1 (en) | 1999-12-23 | 2002-06-18 | The Regents Of The University Of California | Interventions to mimic the effects of calorie restriction |
| JP2005506042A (ja) | 2000-12-12 | 2005-03-03 | ユニヴァーシティー オブ コネティカット | 細胞トランスポーターをコードするポリヌクレオチド、およびその使用方法 |
| US7572575B2 (en) | 2000-12-13 | 2009-08-11 | Massachusetts Institute Of Technology | SIR2 activity |
| WO2002074911A2 (en) * | 2001-03-19 | 2002-09-26 | Wisconsin Alumni Research Foundation | Identification of gene expression alterations underlying the aging process in mammals |
| EP1406489A4 (de) | 2001-06-22 | 2005-08-24 | Univ California | Eukaryontische gene, die an der regulation des lebensalters als erwachsener beteiligt sind |
| CA2450126A1 (en) * | 2001-06-26 | 2003-01-09 | Wisconsin Alumni Research Foundation | Gene expression alterations underlying the retardation of aging by caloric restriction in mammals |
| WO2003025122A2 (en) * | 2001-08-13 | 2003-03-27 | University Of Kentucky Research Foundation | Gene expression profile biomarkers and therapeutic targets for brain aging and age-related cognitive impairment |
| CA2457370A1 (en) * | 2001-08-15 | 2003-02-27 | Elixir Pharmaceuticals, Inc. | Age-associated markers |
| US6964850B2 (en) | 2001-11-09 | 2005-11-15 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US20040014111A1 (en) * | 2002-05-24 | 2004-01-22 | Jun Li | Methods for the identification of IKKalpha function and other genes useful for treatment of imflammatory diseases |
| CA2494066A1 (en) * | 2002-08-09 | 2004-02-19 | Cynthia Kenyon | Eukaryotic genes involved in adult lifespan regulation |
| FR2847269B1 (fr) * | 2002-11-19 | 2006-07-28 | Coletica | Procede d'identification d'une modification eventuelle d'au moins un parametre biologique mettant en oeuvre des cellules vivantes jeunes et agees |
| CA2504144A1 (en) * | 2002-11-26 | 2004-06-10 | Genentech, Inc. | Compositions and methods for the diagnosis of immune related diseases using pro7 |
| US20040191775A1 (en) * | 2003-03-12 | 2004-09-30 | Spindler Stephen R. | Methods of analyzing genes affected by caloric restriction or caloric restriction mimetics |
| WO2005041893A2 (en) * | 2003-10-31 | 2005-05-12 | Queststar Medical, Inc. | Detection of acute myocardial infarction biomarkers |
| US20070275108A1 (en) * | 2003-12-19 | 2007-11-29 | Geesamen Bard J | Life Span Managment |
| US20050266438A1 (en) * | 2004-03-16 | 2005-12-01 | The Regents Of The University Of California | Genetic networks regulated by attenuated GH/IGF1 signaling and caloric restriction |
| US20050228237A1 (en) * | 2004-04-12 | 2005-10-13 | Frank Shallenberger | Method for analyzing the biological age of a subject |
| US7273453B2 (en) * | 2004-04-12 | 2007-09-25 | Frank Shallenberger | Method for analyzing the biological age of a subject |
| WO2005123955A2 (en) * | 2004-06-09 | 2005-12-29 | Children's Medical Center Corporation | Methods and compositions for modifying gene regulation and dna damage in ageing |
| CA2597513C (en) * | 2005-02-15 | 2010-08-10 | Yugenkaisha Japan Tsusyo | Physical strength age measuring system |
| US20070099830A1 (en) | 2005-04-21 | 2007-05-03 | Massachusetts Institute Of Technology | Sirt4 activities |
| US7960605B2 (en) | 2006-03-17 | 2011-06-14 | BioMaker Pharmaceuticals, Inc. | Methods for testing for caloric restriction (CR) mimetics |
| EP2089539B1 (de) * | 2006-10-13 | 2011-12-07 | Metabolon, Inc. | Mit metabolischem alter verbundene biomarker und verfahren zur verwendung davon |
| EP2128275A4 (de) * | 2007-02-23 | 2010-12-08 | Progenika Biopharma Sa | Verfahren und produkt für in-vitro-genotypisierung mit anwendung in der anti-aging-medizin |
| US8420088B2 (en) | 2008-01-28 | 2013-04-16 | Novartis Ag | Methods and compositions using FGF23 fusion polypeptides |
| US7666137B2 (en) * | 2008-04-10 | 2010-02-23 | Frank Shallenberger | Method for analyzing mitochondrial function |
| EP2294216A4 (de) | 2008-05-14 | 2011-11-23 | Dermtech Int | Diagnose von melanom und sonnenpigmentflecken mittels nukleinsäureanalyse |
| EP2331707A4 (de) * | 2008-08-28 | 2012-06-06 | Dermtech Int | Bestimmung des alterbereiches von hautproben |
| EP2406398A4 (de) * | 2009-03-11 | 2012-09-12 | Nestec Sa | Gewebespezifische biomarker für alterung |
| US20110091081A1 (en) * | 2009-10-16 | 2011-04-21 | General Electric Company | Method and system for analyzing the expression of biomarkers in cells in situ in their tissue of origin |
| US8320655B2 (en) * | 2009-10-16 | 2012-11-27 | General Electric Company | Process and system for analyzing the expression of biomarkers in cells |
| US8824769B2 (en) * | 2009-10-16 | 2014-09-02 | General Electric Company | Process and system for analyzing the expression of biomarkers in a cell |
| CA2779606A1 (en) * | 2009-11-10 | 2011-05-19 | Nestec S.A. | Heart aging biomarkers and methods of use |
| JP6226744B2 (ja) | 2010-05-24 | 2017-11-08 | エヌエスイー プロダクツ インコーポレイテッド | 加齢の影響を防止するための経口処方物 |
| WO2013027191A1 (en) | 2011-08-25 | 2013-02-28 | Novartis Ag | Methods and compositions using fgf23 fusion polypeptides |
| US8652518B2 (en) | 2012-04-15 | 2014-02-18 | Jahahreeh Finley | Compositions and methods for the prevention and treatment of diseases or conditions associated with oxidative stress, inflammation, and metabolic dysregulation |
| FR2993282B1 (fr) * | 2012-07-13 | 2017-11-10 | Expanscience Lab | Procede d'identification de marqueurs moleculaires de la peau d'enfant |
| US20190093163A1 (en) * | 2015-06-12 | 2019-03-28 | President And Fellows Of Harvard College | Compositions and methods for maintaining splicing fidelity |
| US20190078162A1 (en) * | 2017-09-14 | 2019-03-14 | OneSkin Technologies, Inc. | In vitro methods for skin therapeutic compound discovery using skin age biomarkers |
| EP3752645A4 (de) | 2018-02-14 | 2022-04-13 | Dermtech, Inc. | Neue gen-klassifikatoren und deren verwendung bei nicht-melanom-hautkrebs |
| AU2020247911A1 (en) | 2019-03-26 | 2021-11-11 | Dermtech, Llc | Novel gene classifiers and uses thereof in skin cancers |
| TWI862641B (zh) | 2019-07-22 | 2024-11-21 | 美商第一美膚公司 | 具有抗老化功效之多肽及其用途 |
| US11227691B2 (en) | 2019-09-03 | 2022-01-18 | Kpn Innovations, Llc | Systems and methods for selecting an intervention based on effective age |
| US11250337B2 (en) | 2019-11-04 | 2022-02-15 | Kpn Innovations Llc | Systems and methods for classifying media according to user negative propensities |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744300A (en) * | 1993-03-24 | 1998-04-28 | Geron Corporation | Methods and reagents for the identification and regulation of senescence-related genes |
| US6087102A (en) * | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
| US6406853B1 (en) | 1999-12-23 | 2002-06-18 | The Regents Of The University Of California | Interventions to mimic the effects of calorie restriction |
-
2000
- 2000-08-08 EP EP00952626A patent/EP1200629B1/de not_active Expired - Lifetime
- 2000-08-08 US US09/630,567 patent/US6569624B1/en not_active Expired - Lifetime
- 2000-08-08 AU AU65289/00A patent/AU782102B2/en not_active Expired
- 2000-08-08 CA CA2381777A patent/CA2381777C/en not_active Expired - Lifetime
- 2000-08-08 WO PCT/US2000/021603 patent/WO2001012851A2/en not_active Ceased
- 2000-08-08 AT AT00952626T patent/ATE384137T1/de not_active IP Right Cessation
- 2000-08-08 DE DE60037817T patent/DE60037817D1/de not_active Expired - Lifetime
-
2002
- 2002-12-02 US US10/307,706 patent/US20030157526A1/en not_active Abandoned
-
2006
- 2006-11-20 US US11/974,837 patent/US20080254464A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2381777A1 (en) | 2001-02-22 |
| EP1200629A2 (de) | 2002-05-02 |
| US6569624B1 (en) | 2003-05-27 |
| DE60037817D1 (de) | 2008-03-06 |
| US20030157526A1 (en) | 2003-08-21 |
| AU6528900A (en) | 2001-03-13 |
| EP1200629B1 (de) | 2008-01-16 |
| WO2001012851A2 (en) | 2001-02-22 |
| WO2001012851A3 (en) | 2001-08-23 |
| US20080254464A1 (en) | 2008-10-16 |
| CA2381777C (en) | 2011-10-04 |
| AU782102B2 (en) | 2005-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |