ATE385516T1 - Expressionsvektoren die signalpeptide aus bakteriophagen kodieren - Google Patents

Expressionsvektoren die signalpeptide aus bakteriophagen kodieren

Info

Publication number
ATE385516T1
ATE385516T1 AT02743424T AT02743424T ATE385516T1 AT E385516 T1 ATE385516 T1 AT E385516T1 AT 02743424 T AT02743424 T AT 02743424T AT 02743424 T AT02743424 T AT 02743424T AT E385516 T1 ATE385516 T1 AT E385516T1
Authority
AT
Austria
Prior art keywords
signal peptides
expression vectors
bacteriophages
encoding signal
vectors
Prior art date
Application number
AT02743424T
Other languages
English (en)
Inventor
David Paul Humphreys
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Application granted granted Critical
Publication of ATE385516T1 publication Critical patent/ATE385516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
AT02743424T 2001-07-05 2002-07-05 Expressionsvektoren die signalpeptide aus bakteriophagen kodieren ATE385516T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0116460.7A GB0116460D0 (en) 2001-07-05 2001-07-05 Biological products

Publications (1)

Publication Number Publication Date
ATE385516T1 true ATE385516T1 (de) 2008-02-15

Family

ID=9917985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02743424T ATE385516T1 (de) 2001-07-05 2002-07-05 Expressionsvektoren die signalpeptide aus bakteriophagen kodieren

Country Status (10)

Country Link
US (1) US7244587B2 (de)
EP (1) EP1402036B1 (de)
JP (1) JP2004533264A (de)
AT (1) ATE385516T1 (de)
AU (1) AU2002345213A1 (de)
CA (1) CA2452359A1 (de)
DE (1) DE60224930T2 (de)
ES (1) ES2299582T3 (de)
GB (1) GB0116460D0 (de)
WO (1) WO2003004636A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7527947B2 (en) 2004-06-14 2009-05-05 Novozymes A/S Signal peptide for producing a polypeptide
EP1756273B1 (de) * 2004-06-14 2009-10-07 Novozymes A/S Signalpeptid zur herstellung eines polypeptids
EP2059590B1 (de) 2006-07-14 2014-12-31 Novozymes, Inc. Verfahren zur produktion sezernierter polypeptide mit biologischer aktivität
KR101698040B1 (ko) * 2013-06-27 2017-01-24 주식회사 중겸 M13 박테리오파지에 대한 단일 도메인 항체 및 이를 포함하는 면역센서 융합 단백질
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN110637089B (zh) * 2017-03-22 2024-08-02 新加坡科技研究局 蛋白质表达构建体及其方法
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476198B1 (en) 1993-07-13 2002-11-05 The Scripps Research Institute Multispecific and multivalent antigen-binding polypeptide molecules

Also Published As

Publication number Publication date
EP1402036B1 (de) 2008-02-06
US7244587B2 (en) 2007-07-17
US20040259210A1 (en) 2004-12-23
CA2452359A1 (en) 2003-01-16
ES2299582T3 (es) 2008-06-01
DE60224930D1 (de) 2008-03-20
WO2003004636A3 (en) 2003-06-26
GB0116460D0 (en) 2001-08-29
JP2004533264A (ja) 2004-11-04
DE60224930T2 (de) 2009-02-05
EP1402036A2 (de) 2004-03-31
AU2002345213A1 (en) 2003-01-21
WO2003004636A2 (en) 2003-01-16

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