ATE386561T1 - Transdermale transportvorrichtung mit mikronadeln - Google Patents

Transdermale transportvorrichtung mit mikronadeln

Info

Publication number
ATE386561T1
ATE386561T1 AT02782208T AT02782208T ATE386561T1 AT E386561 T1 ATE386561 T1 AT E386561T1 AT 02782208 T AT02782208 T AT 02782208T AT 02782208 T AT02782208 T AT 02782208T AT E386561 T1 ATE386561 T1 AT E386561T1
Authority
AT
Austria
Prior art keywords
needle
transport device
microneedles
transdermal transport
reservoir
Prior art date
Application number
AT02782208T
Other languages
English (en)
Inventor
Aimee Angel
Ian Hunter
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of ATE386561T1 publication Critical patent/ATE386561T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401—Functional features
    • A61M2005/1405—Patient controlled analgesia [PCA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1581—Right-angle needle-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266—Shape memory materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/65—Impedance, e.g. conductivity, capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Medical Informatics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT02782208T 2001-10-26 2002-10-21 Transdermale transportvorrichtung mit mikronadeln ATE386561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33842501P 2001-10-26 2001-10-26
US39948902P 2002-07-29 2002-07-29

Publications (1)

Publication Number Publication Date
ATE386561T1 true ATE386561T1 (de) 2008-03-15

Family

ID=26991185

Family Applications (3)

Application Number Title Priority Date Filing Date
AT02789233T ATE420680T1 (de) 2001-10-26 2002-10-18 Mikronadeltransportvorrichtung
AT02782208T ATE386561T1 (de) 2001-10-26 2002-10-21 Transdermale transportvorrichtung mit mikronadeln
AT02784221T ATE419885T1 (de) 2001-10-26 2002-10-22 Transdermale transportvorrichtung mit ansaugung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02789233T ATE420680T1 (de) 2001-10-26 2002-10-18 Mikronadeltransportvorrichtung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02784221T ATE419885T1 (de) 2001-10-26 2002-10-22 Transdermale transportvorrichtung mit ansaugung

Country Status (8)

Country Link
US (7) US7429258B2 (de)
EP (5) EP1439871B1 (de)
JP (10) JP2005525141A (de)
AT (3) ATE420680T1 (de)
AU (3) AU2002353840B2 (de)
CA (5) CA2464483C (de)
DE (3) DE60230896D1 (de)
WO (5) WO2003037403A1 (de)

Families Citing this family (416)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482145B1 (en) 2000-02-14 2002-11-19 Obtech Medical Ag Hydraulic anal incontinence treatment
US6471635B1 (en) 2000-02-10 2002-10-29 Obtech Medical Ag Anal incontinence disease treatment with controlled wireless energy supply
US6503189B1 (en) 1999-08-12 2003-01-07 Obtech Medical Ag Controlled anal incontinence disease treatment
US6464628B1 (en) 1999-08-12 2002-10-15 Obtech Medical Ag Mechanical anal incontinence
WO2001047434A2 (en) 2000-02-10 2001-07-05 Potencia Medical Ag Mechanical impotence treatment apparatus
DE60134585D1 (de) 2000-02-10 2008-08-07 Potencia Medical Ag Kontrollierte Harninkontinenzbehandlung
CN1222254C (zh) 2000-02-10 2005-10-12 波滕西亚医疗公司 用无线能量源进行尿失禁治疗
WO2001050832A2 (en) * 2000-02-11 2001-07-19 Potencia Medical Ag Controlled impotence treatment
CN1400888A (zh) 2000-02-11 2003-03-05 波滕西亚医疗公司 带能量变换装置的阳痿治疗设备
EP1255514B1 (de) 2000-02-14 2006-04-26 Potencia Medical AG Männliche impotentzprothesevorrichtung mit drahtloser energieversorgung
US7442165B2 (en) 2000-02-14 2008-10-28 Obtech Medical Ag Penile prosthesis
US20030100929A1 (en) 2000-02-14 2003-05-29 Peter Forsell Controlled penile prosthesis
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
EP1227094B1 (de) * 2001-01-30 2005-12-14 Nissan Chemical Industries Ltd. Isocyanurate und Verfahren zu deren Herstellung
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US6966880B2 (en) * 2001-10-16 2005-11-22 Agilent Technologies, Inc. Universal diagnostic platform
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
JP4125234B2 (ja) 2001-11-01 2008-07-30 スパイン・ウェイブ・インコーポレーテッド 椎間板間の終板の前処理のための装置及び方法
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7858112B2 (en) * 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) * 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US20040039289A1 (en) * 2002-04-30 2004-02-26 Christensen Lars Hofmann Needle insertion sensor
US7722595B2 (en) * 2002-05-06 2010-05-25 Becton, Dickinson And Company Method and device for controlling drug pharmacokinetics
EP1389476A1 (de) * 2002-08-14 2004-02-18 Precimedix S.A. Programmiergerät für eine Medikamentinjektionpumpe
BR0313890A (pt) * 2002-08-30 2005-07-26 Becton Dickinson Co Método de controle da farmacocinética de compostos imunomoduladores
US20120296233A9 (en) * 2002-09-05 2012-11-22 Freeman Dominique M Methods and apparatus for an analyte detecting device
US20040106894A1 (en) 2002-09-06 2004-06-03 Massachusetts Institute Of Technology Needleless drug injection device
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
CN100346746C (zh) * 2003-03-06 2007-11-07 生命扫描有限公司 用于穿刺皮组织的系统和方法
WO2006001797A1 (en) * 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US20070065463A1 (en) 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
EP1656178A1 (de) * 2003-08-04 2006-05-17 Alza Corporation Verfahren und vorrichtung zur verbesserung des flusses transdermaler agentien
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
EP1680014A4 (de) 2003-10-14 2009-01-21 Pelikan Technologies Inc Verfahren und gerät für eine variable anwenderschnittstelle
EP1527792A1 (de) 2003-10-27 2005-05-04 Novo Nordisk A/S Eine auf die Haut anbringbare medizinische Injektionsvorrichtung
US20070191815A1 (en) 2004-09-13 2007-08-16 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
US7097631B2 (en) * 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
US7361182B2 (en) 2003-12-19 2008-04-22 Lightnix, Inc. Medical lancet
DK1706019T3 (da) * 2003-12-22 2009-02-02 Paul Hadvary Dermalt fastgjort sensorindretning
JP2007516781A (ja) * 2003-12-29 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー 医療用具および該医療用具を含むキット
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
NZ585119A (en) * 2004-03-08 2011-08-26 Ichor Medical Systems Inc Medical injector with surrounding electrical field generating penetrating electrodes
AU2005243727B2 (en) * 2004-04-12 2011-04-28 Allergan, Inc. Multi-site injection system
WO2005118060A2 (en) * 2004-04-30 2005-12-15 Boston Scientific Limited Apparatus with partially insulated needle for measuring tissue impedance and method using same
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
US8247946B2 (en) 2004-06-14 2012-08-21 Massachusetts Institute Of Technology Electrochemical actuator
EP1784890A4 (de) 2004-06-14 2010-04-07 Massachusetts Inst Technology Elektrochemische verfahren, einrichtungen und strukturen
US7872396B2 (en) 2004-06-14 2011-01-18 Massachusetts Institute Of Technology Electrochemical actuator
US8337557B2 (en) * 2004-06-29 2012-12-25 Spine Wave, Inc. Apparatus and kit for injecting a curable biomaterial into an intervertebral space
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
US8696619B2 (en) * 2004-08-10 2014-04-15 Robert P. Schnall Drug delivery devices
ATE490037T1 (de) 2004-08-16 2010-12-15 Functional Microstructures Ltd Verfahren zur herstellung einer mikronadel oder eines mikroimplantats
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
BRPI0517749A (pt) * 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
EP1827564B1 (de) * 2004-11-18 2015-07-29 3M Innovative Properties Company Maskierungsverfahren zum beschichten einer mikronadelanordnung
ATE504328T1 (de) 2004-11-18 2011-04-15 3M Innovative Properties Co Mikronadelanordungsapplikator und halter
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
US20080009801A1 (en) * 2004-12-02 2008-01-10 Nickel Janice H Method for dispensing material into a drug delivery device
CN100367906C (zh) * 2004-12-08 2008-02-13 圣美迪诺医疗科技(湖州)有限公司 皮下植入式生物传感器
US7850645B2 (en) 2005-02-11 2010-12-14 Boston Scientific Scimed, Inc. Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
US7833189B2 (en) * 2005-02-11 2010-11-16 Massachusetts Institute Of Technology Controlled needle-free transport
EP1709989A1 (de) * 2005-04-04 2006-10-11 Christoph Burckhardt AG Tätowierpistolenspitze
EP1871459B1 (de) * 2005-04-07 2019-06-19 3M Innovative Properties Company SYSTEM ZUR ERFASSUNG DER WERKZEUGRüCKMELDUNG
EP1709906A1 (de) * 2005-04-07 2006-10-11 F. Hoffmann-La Roche Ag Verfahren und Vorrichtung zur Entnahme von Körperflüssigkeit
US8298172B2 (en) 2005-04-13 2012-10-30 Novo Nordisk A/S Medical skin mountable device and system
EP2921169A1 (de) * 2005-05-24 2015-09-23 Chrono Therapeutics, Inc. Tragbare Wirkstofffreisetzungsvorrichtung mit abnehmbarem und austauschbarem Verabreichungs- oder Dosierungselement
US8372040B2 (en) 2005-05-24 2013-02-12 Chrono Therapeutics, Inc. Portable drug delivery device including a detachable and replaceable administration or dosing element
WO2006128034A1 (en) * 2005-05-25 2006-11-30 Georgia Tech Research Corporation Microneedles and methods for microinfusion
JP5148274B2 (ja) * 2005-05-27 2013-02-20 オリンパス株式会社 被検体内導入装置
US8505544B2 (en) * 2005-05-31 2013-08-13 The Board Of Trustees Of The Leland Stanford Junior University Optically-implemented microsurgery system and approach
EP1893256B1 (de) * 2005-06-16 2012-09-26 Novo Nordisk A/S Verfahren und vorrichtung zur unterstützung von patienten bei der selbstverabreichung von medikamenten
US20080195035A1 (en) * 2005-06-24 2008-08-14 Frederickson Franklyn L Collapsible Patch and Method of Application
WO2007002521A2 (en) * 2005-06-27 2007-01-04 3M Innovative Properties Company Microneedle array applicator device
DE602006005674D1 (de) 2005-07-06 2009-04-23 Vascular Pathways Inc Gerät zur intravenösen kathetereinführung und verwendungsverfahren
IL175460A (en) 2006-05-07 2011-05-31 Doron Aurbach Drug delivery device
US9687186B2 (en) 2005-07-21 2017-06-27 Steadymed Ltd. Drug delivery device
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
JP4935286B2 (ja) * 2005-10-12 2012-05-23 パナソニック株式会社 血液センサ
EP1940489A1 (de) 2005-10-17 2008-07-09 Novo Nordisk A/S Belüftetes arzneireservoir
EP2926847B1 (de) * 2005-11-02 2022-05-25 MedicalTree Patents Ltd. Implantierbare infusionsvorrichtung mit ausfahrbarer und einziehbarer nadel
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US9636035B2 (en) * 2005-12-14 2017-05-02 Scibase Ab Medical apparatus for determination of biological conditions using impedance measurements
JP4402648B2 (ja) * 2005-12-16 2010-01-20 オリンパス株式会社 被検体内導入装置
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
EP1815790A1 (de) * 2006-02-04 2007-08-08 Roche Diagnostics GmbH Stechgerät mit Impedanzmesseinrichtung
MX2008010341A (es) * 2006-02-09 2008-11-18 Deka Products Lp Sistemas y metodos adhesivos y perifericos para dispositivos medicos.
US11318249B2 (en) 2006-02-09 2022-05-03 Deka Products Limited Partnership Infusion pump assembly
EP1992386B1 (de) * 2006-02-10 2011-11-09 Hisamitsu Pharmaceutical Co., Inc. Transdermales arzneiverabreichungsgerät mit mikronadeln
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US7981034B2 (en) 2006-02-28 2011-07-19 Abbott Diabetes Care Inc. Smart messages and alerts for an infusion delivery and management system
EP2319558B1 (de) 2006-03-14 2014-05-21 University Of Southern California Mems-Vorrichtung zur Wirkstofffreisetzung
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
US8197435B2 (en) * 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
WO2007131050A2 (en) * 2006-05-02 2007-11-15 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
US7621895B2 (en) * 2006-05-17 2009-11-24 Abbott Cardiovascular Systems Inc. Needle array devices and methods
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods
US20090171269A1 (en) * 2006-06-29 2009-07-02 Abbott Diabetes Care, Inc. Infusion Device and Methods Therefor
US9119582B2 (en) 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
WO2008016331A1 (en) * 2006-08-01 2008-02-07 Agency For Science, Technology And Research Ultrasonic enhanced microneedles
US8206296B2 (en) 2006-08-07 2012-06-26 Abbott Diabetes Care Inc. Method and system for providing integrated analyte monitoring and infusion system therapy management
US8932216B2 (en) 2006-08-07 2015-01-13 Abbott Diabetes Care Inc. Method and system for providing data management in integrated analyte monitoring and infusion system
JP2010502267A (ja) * 2006-08-28 2010-01-28 エージェンシー・フォー・サイエンス・テクノロジー・アンド・リサーチ マイクロニードルおよびマイクロニードルの製造方法
CA2661912A1 (en) * 2006-08-29 2008-03-06 Alza Corporation Drug electrotransport with hydration measurement of hydratable reservoir
WO2008036043A1 (en) * 2006-09-18 2008-03-27 Agency For Science, Technology And Research Needle structures and methods for fabricating needle structures
EP2079860B1 (de) 2006-10-05 2013-08-07 Technion Research & Development Foundation Ltd. Mikroröhrchen und herstellungsverfahren dafür
JP2010508006A (ja) * 2006-10-25 2010-03-11 エフ．ホフマン−ラ ロシュ アーゲー 医療用電気機器用の無停電電力供給装置
WO2008052221A2 (en) * 2006-10-27 2008-05-02 Aretais, Inc. Use of coherent raman techniques for medical diagnostic and therapeutic purposes, and calibration techniques for same
US10525246B2 (en) * 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US8845530B2 (en) * 2007-01-02 2014-09-30 Isense Corporation Resposable biosensor assembly and method of sensing
FR2912919B1 (fr) * 2007-02-22 2009-05-01 Bernard Perriere Dispositif d'injection miniaturise a usage medical
US20080249469A1 (en) * 2007-03-22 2008-10-09 Ponnambalam Selvaganapathy Method and apparatus for active control of drug delivery using electro-osmotic flow control
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
JP5139518B2 (ja) 2007-05-07 2013-02-06 バスキュラー・パスウェイズ・インコーポレイテッド 静脈カテーテル挿入装置
US20090069830A1 (en) * 2007-06-07 2009-03-12 Piezo Resonance Innovations, Inc. Eye surgical tool
DK2158908T3 (da) * 2007-06-21 2013-07-29 Fujimoto Co Ltd Sammensætning til transdermal administrering
US8641618B2 (en) 2007-06-27 2014-02-04 Abbott Diabetes Care Inc. Method and structure for securing a monitoring device element
US8085151B2 (en) 2007-06-28 2011-12-27 Abbott Diabetes Care Inc. Signal converting cradle for medical condition monitoring and management system
US8043229B2 (en) * 2007-06-29 2011-10-25 Actuated Medical, Inc. Medical tool for reduced penetration force
US10219832B2 (en) 2007-06-29 2019-03-05 Actuated Medical, Inc. Device and method for less forceful tissue puncture
US9987468B2 (en) 2007-06-29 2018-06-05 Actuated Medical, Inc. Reduced force device for intravascular access and guidewire placement
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US8328738B2 (en) * 2007-06-29 2012-12-11 Actuated Medical, Inc. Medical tool for reduced penetration force with feedback means
EP2178584A2 (de) * 2007-07-26 2010-04-28 Entra Pharmaceuticals Inc. Infusionspumpe mit einem elektrochemischen aktuator mit veränderlichem volumen
CA2941187C (en) * 2007-08-14 2021-03-02 Fred Hutchinson Cancer Research Center Needle array assembly and method for delivering therapeutic agents
WO2009029572A1 (en) * 2007-08-24 2009-03-05 Deka Products Limited Partnership Microneedle systems and apparatus
JP5411138B2 (ja) * 2007-08-24 2014-02-12 エイジェンシー フォー サイエンス， テクノロジー アンド リサーチ 皮膚貫通検出システム
US9096845B2 (en) * 2007-08-29 2015-08-04 Technion Research & Development Foundation Limited Encapsulation of bacteria and viruses in electrospun fibers
US20090088682A1 (en) * 2007-09-28 2009-04-02 Seattle Medical Technologies Wearable infusion device
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
WO2010042045A1 (en) 2008-10-10 2010-04-15 Milux Holding S.A. A system, an apparatus, and a method for treating a sexual dysfunctional female patient
WO2009079589A2 (en) 2007-12-17 2009-06-25 New World Pharmaceuticals, Llc Integrated intra-dermal delivery, diagnostic and communication system
EP2666510B1 (de) 2007-12-20 2017-10-18 University Of Southern California Vorrichtung zur kontrollierten Abgabe von Therapeutika
WO2009088956A2 (en) 2007-12-31 2009-07-16 Deka Products Limited Partnership Infusion pump assembly
FI20075978A0 (fi) * 2007-12-31 2007-12-31 Katja Paassilta Järjestely ja menetelmä
US11357910B2 (en) 2007-12-31 2022-06-14 Deka Products Limited Partnership Pump assembly with switch
CN114796703B (zh) 2007-12-31 2025-10-21 德卡产品有限公司 输注泵组件
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
CA2749771C (en) * 2008-01-28 2018-05-01 Milux Holding S.A. A drainage device comprising an active filter
EP3476371B1 (de) 2008-01-29 2022-03-09 Implantica Patent Ltd. Vorrichtung zur behandlung von refluxösophagitis
WO2009104175A2 (en) * 2008-02-21 2009-08-27 Technion Research & Development Foundation Ltd. Use of electrospun microtubes for drug delivery
WO2009108836A1 (en) * 2008-02-29 2009-09-03 Path Scientific, Llc Unitized painfree blood glucose measuring device
JP2009222474A (ja) * 2008-03-14 2009-10-01 Panasonic Corp 微量液体供給装置および微量液体供給方法
USD610690S1 (en) 2008-04-16 2010-02-23 Hisamitsu Pharmaceutical Co., Inc. Combined medical patch and package
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
EP2323716B1 (de) 2008-05-08 2015-03-04 MiniPumps, LLC Arzneiabgabepumpen
CN102202719B (zh) 2008-05-08 2014-11-26 迷你泵有限责任公司 可植入泵和用于可植入泵的插管
WO2009142741A1 (en) 2008-05-21 2009-11-26 Theraject, Inc. Method of manufacturing solid solution peforator patches and uses thereof
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
JP2011526889A (ja) 2008-06-30 2011-10-20 アフギン ファーマ，エルエルシー 局所局部的神経作用療法
WO2010004721A1 (ja) * 2008-07-08 2010-01-14 パナソニック株式会社 導電性高分子を用いた流体搬送装置
US8868176B2 (en) * 2008-07-22 2014-10-21 New York University Microelectrode-equipped subdural therapeutic agent delivery strip
DK2328636T3 (da) * 2008-08-28 2013-09-02 Medingo Ltd Anordning til forbedret subkutan insulinabsorption
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
EP2349170B1 (de) 2008-10-10 2023-09-27 Implantica Patent Ltd. Vorrichtung zur behandlung von weiblicher sexueller dysfunktion
US20210378811A1 (en) * 2008-10-10 2021-12-09 Peter Forsell Fastening means for implantable medical control assembly
AU2009302955B2 (en) 2008-10-10 2017-01-05 Implantica Patent Ltd. Fastening means for implantable medical control assembly
WO2010042058A1 (en) 2008-10-10 2010-04-15 Milux Holding S.A. An improved artificial valve
US10583234B2 (en) 2008-10-10 2020-03-10 Peter Forsell Heart help device, system and method
WO2010042012A1 (en) 2008-10-10 2010-04-15 Milux Holding Sa Heart help device, system, and method
WO2010052692A1 (en) * 2008-11-04 2010-05-14 Janisys Limited A transfer device for transferring a substance between the device and a subject
SI3187219T1 (sl) 2008-12-02 2020-09-30 Allergan, Inc. Injekcijska naprava
US20110301628A1 (en) * 2008-12-05 2011-12-08 Yossi Gross Techniques for use with a nail penetration device
WO2010070628A1 (en) * 2008-12-19 2010-06-24 Janisys Limited A fluid transfer device and an active substance cartridge for the fluid transfer device, and a method for controlling the pressure at which an active substance is delivered to a subject from a fluid transfer device
US20100187132A1 (en) * 2008-12-29 2010-07-29 Don Alden Determination of the real electrochemical surface areas of screen printed electrodes
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20110105951A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
WO2010101621A1 (en) * 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Devices and methods for the analysis of an extractable medium
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
WO2010107707A2 (en) 2009-03-17 2010-09-23 Savage Walter T External defibrillator
US8781576B2 (en) * 2009-03-17 2014-07-15 Cardiothrive, Inc. Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current
DE102009002019A1 (de) 2009-03-31 2010-10-07 Robert Bosch Gmbh Applikator zur Behandlung von Haut
EP2425209A4 (de) 2009-04-29 2013-01-09 Abbott Diabetes Care Inc Verfahren und system für die echtzeit-kalibrierung eines analytsensors mit rückwirkender füllung
WO2010125551A2 (en) * 2009-04-29 2010-11-04 Janisys Limited A micro-needle device and apparatus and a method for applying a micro-needle element to a site on the skin of a subject
EP2432525A1 (de) * 2009-05-20 2012-03-28 Sanofi-Aventis Deutschland GmbH Arzneimittelabgabevorrichtung
US9949812B2 (en) 2009-07-17 2018-04-24 Peter Forsell Vaginal operation method for the treatment of anal incontinence in women
US10952836B2 (en) 2009-07-17 2021-03-23 Peter Forsell Vaginal operation method for the treatment of urinary incontinence in women
EP2724739B1 (de) 2009-07-30 2015-07-01 Tandem Diabetes Care, Inc. Tragbares Infusionspumpensystem
ES2661063T3 (es) 2009-07-31 2018-03-27 3M Innovative Properties Company Matrices de micro agujas huecas
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
KR101697388B1 (ko) 2009-08-18 2017-01-17 미니펌프스, 엘엘씨 적응 제어기를 갖춘 전해 약품 운반 펌프
US8758271B2 (en) 2009-09-01 2014-06-24 Massachusetts Institute Of Technology Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties
US20110060202A1 (en) * 2009-09-08 2011-03-10 Seth Adrian Miller Dehydration detector using micro-needles
JP5701882B2 (ja) * 2009-09-10 2015-04-15 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬剤容器
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
US20120003601A1 (en) 2009-12-15 2012-01-05 Massachusetts Institute Of Technology Jet Injector Use In Oral Evaluation
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
EP3243435A1 (de) * 2010-01-13 2017-11-15 Seventh Sense Biosystems, Inc. Schnittstellen für eine probenentnahmevorrichtung
EP2523706B1 (de) * 2010-01-13 2019-08-21 Seventh Sense Biosystems, Inc. Schnelle ausgabe und/oder entnahme von flüssigkeiten
JP5826766B2 (ja) * 2010-01-13 2015-12-02 セブンス センス バイオシステムズ，インコーポレーテッド 試料採取デバイスインタフェース
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US8366667B2 (en) * 2010-02-11 2013-02-05 Baxter International Inc. Flow pulsatility dampening devices
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8920376B2 (en) 2010-04-20 2014-12-30 Minipumps, Llc Fill-status sensors for drug pump devices
KR20130058012A (ko) 2010-04-28 2013-06-03 킴벌리-클라크 월드와이드, 인크. 사출 성형된 마이크로니들 어레이 및 마이크로니들 어레이의 형성 방법
MX345837B (es) 2010-04-28 2017-02-16 Kimberly-Clark Worldwide Incorporated Dispositivo para la entrega de un medicamento para la artritis reumatoide.
EP2563455A4 (de) 2010-04-28 2014-02-19 Kimberly Clark Co Verfahren zur erhöhung der durchlässigkeit einer epithelialbarriere
US9629979B2 (en) * 2010-04-28 2017-04-25 Sanovas, Inc. Pressure/Vacuum actuated catheter drug delivery probe
WO2011135531A2 (en) 2010-04-28 2011-11-03 Kimberly-Clark Worldwide, Inc. MEDICAL DEVICES FOR DELIVERY OF siRNA
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
WO2011140359A2 (en) * 2010-05-05 2011-11-10 Springleaf Therapeutics, Inc. Systems and methods for delivering a therapeutic agent
US8932258B2 (en) 2010-05-14 2015-01-13 C. R. Bard, Inc. Catheter placement device and method
US11925779B2 (en) 2010-05-14 2024-03-12 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US9950139B2 (en) 2010-05-14 2018-04-24 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US9872971B2 (en) 2010-05-14 2018-01-23 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US10384039B2 (en) 2010-05-14 2019-08-20 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US9125625B2 (en) 2010-06-10 2015-09-08 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
US9227021B2 (en) 2010-06-29 2016-01-05 Genesis Biosystems, Inc. Microneedle roller (MNR) infusion system
JP2013538069A (ja) 2010-07-16 2013-10-10 セブンス センス バイオシステムズ，インコーポレーテッド 流体移動デバイスのための低圧環境
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US9420952B2 (en) 2010-07-27 2016-08-23 Carefusion 303, Inc. Temperature probe suitable for axillary reading
US9357929B2 (en) 2010-07-27 2016-06-07 Carefusion 303, Inc. System and method for monitoring body temperature of a person
US9615792B2 (en) 2010-07-27 2017-04-11 Carefusion 303, Inc. System and method for conserving battery power in a patient monitoring system
US8814792B2 (en) 2010-07-27 2014-08-26 Carefusion 303, Inc. System and method for storing and forwarding data from a vital-signs monitor
US9585620B2 (en) 2010-07-27 2017-03-07 Carefusion 303, Inc. Vital-signs patch having a flexible attachment to electrodes
US9055925B2 (en) 2010-07-27 2015-06-16 Carefusion 303, Inc. System and method for reducing false alarms associated with vital-signs monitoring
US9017255B2 (en) 2010-07-27 2015-04-28 Carefusion 303, Inc. System and method for saving battery power in a patient monitoring system
DE102010038733A1 (de) * 2010-07-30 2012-02-02 Robert Bosch Gmbh Modulare Mikronadel-Transportvorrichtung
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US9173994B2 (en) * 2010-08-20 2015-11-03 Purdue Research Foundation Touch-actuated micropump for transdermal drug delivery and method of use
KR20140039132A (ko) 2010-09-27 2014-04-01 스테디메드 리미티드 크기-효율적 약품-전달 장치
JP5934710B2 (ja) 2010-10-07 2016-06-15 マサチューセッツ インスティテュート オブ テクノロジー ローレンツ力直動型の無針式ジェット注射システムを用いた固形物および／または流体の供給
CN107096101A (zh) 2010-10-07 2017-08-29 麻省理工学院 使用伺服控制的无针注射器的注射方法
EP2627292B1 (de) 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Vorrichtung für okularen zugang
WO2012058192A1 (en) * 2010-10-26 2012-05-03 7944942 Canada Inc. Automatic medication injection device
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
EP2637562B1 (de) 2010-11-09 2016-01-27 Seventh Sense Biosystems, Inc. Systeme und schnittstellen zur blutabnahme
WO2012083174A2 (en) 2010-12-17 2012-06-21 Massachusetts Institute Of Technology Electrochemical actuators
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US10130761B2 (en) 2011-02-09 2018-11-20 Becton, Dickinson And Company Infusion systems
EP3563898B1 (de) 2011-02-25 2020-11-11 C.R. Bard, Inc. Vorrichtung zum einsetzen medizinischer komponenten mit einer einziehbaren nadel
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
WO2012139593A2 (en) * 2011-04-15 2012-10-18 Rigshospitalet Copenhagen University Hospital System and method for injecting a substance into a human body
US20140163456A1 (en) * 2011-04-19 2014-06-12 Invisiderm, Llc Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof
BR112013027010A2 (pt) * 2011-04-19 2016-12-27 Invisiderm Llc método de produzir substâncias com gás supersaturado, dispositivo para sua entrega trasdérmica, e seus usos
JP2014516644A (ja) 2011-04-29 2014-07-17 セブンス センス バイオシステムズ，インコーポレーテッド 血斑または他の体液の収集および／または操作のためのデバイスおよび方法
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
EP2701600B1 (de) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Ausgabe und/oder aufnahme von flüssigkeiten
USD903101S1 (en) 2011-05-13 2020-11-24 C. R. Bard, Inc. Catheter
US8636696B2 (en) * 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
JP2014533523A (ja) 2011-09-02 2014-12-15 ザ レジェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア バイオセンシングおよび薬剤供給のためのマイクロ針アレイ
JP6535464B2 (ja) 2011-10-27 2019-06-26 ソレント・セラピューティクス・インコーポレイテッド 生理活性薬剤の送達のための移植可能な装置
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
MX343262B (es) 2011-10-27 2016-10-28 Kimberly Clark Co Administración transdérmica de agentes bioactivos de alta viscosidad.
AU2012328457A1 (en) 2011-10-28 2014-04-24 Presage Biosciences, Inc. Methods for drug delivery
US9317656B2 (en) 2011-11-23 2016-04-19 Abbott Diabetes Care Inc. Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
JP2015501844A (ja) 2011-12-16 2015-01-19 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
DE102011089723A1 (de) * 2011-12-23 2013-06-27 Robert Bosch Gmbh Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays
US10130800B2 (en) 2012-01-27 2018-11-20 Invisiderm, Llc Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof
WO2013136176A1 (en) * 2012-03-13 2013-09-19 Becton Dickinson France Injection device having a miniaturized drug delivery portion
ES2672239T3 (es) 2012-03-15 2018-06-13 Steadymed Ltd. Reducción mejorada del dolor en el lugar de infusión para dispositivos de administración de fármacos
ES2715311T3 (es) 2012-03-19 2019-06-03 Steadymed Ltd Mecanismo de conexión de fluido para bombas tipo parche
KR20130114996A (ko) * 2012-04-10 2013-10-21 삼성디스플레이 주식회사 표시 장치 및 그 제조방법
HK1209658A1 (en) 2012-05-01 2016-04-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
CN108209994B (zh) * 2012-07-06 2021-05-07 通用医疗公司 皮肤病学治疗的方法和装置
US12161831B2 (en) 2012-09-13 2024-12-10 Avraham Amir Microneedles and compositions for skin augmentation
US9782538B2 (en) 2012-09-27 2017-10-10 Becton, Dickinson And Company Angled inserter for drug infusion
KR102467714B1 (ko) 2012-11-08 2022-11-16 클리어사이드 바이오메디컬, 인코포레이드 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치
ES2921623T3 (es) 2012-11-26 2022-08-30 Modernatx Inc ARN modificado terminalmente
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
JP2016504050A (ja) 2013-01-17 2016-02-12 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 細胞表現型の改変のためのシグナルセンサーポリヌクレオチド
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
CN105102054B (zh) 2013-01-30 2018-04-20 血管通路股份有限公司 用于静脉穿刺和导管放置的系统和方法
EP2961471B1 (de) * 2013-02-28 2023-10-25 Sorrento Therapeutics, Inc. Vorrichtung zur transdermalen wirkstofffreisetzung
CA2903748C (en) 2013-03-12 2021-11-02 Corium International, Inc. Microprojection applicators
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
JP6098250B2 (ja) * 2013-03-14 2017-03-22 セイコーエプソン株式会社 液体輸送装置
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US10080839B2 (en) 2013-03-14 2018-09-25 Becton, Dickinson And Company Angled inserter for drug infusion
US9821113B2 (en) 2013-03-15 2017-11-21 Becton, Dickinson And Company Automatic angled infusion set assembly
CN105142695B (zh) * 2013-03-15 2020-06-02 安进公司 身体轮廓可调适的自动注射器装置
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2014150285A2 (en) * 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US9603995B2 (en) 2013-03-15 2017-03-28 Tandem Diabetes Care. Inc. Device and method for setting therapeutic parameters for an infusion device
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
US10188550B2 (en) 2013-06-03 2019-01-29 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
US10149973B2 (en) 2013-06-14 2018-12-11 Cardiothrive, Inc. Multipart non-uniform patient contact interface and method of use
US9616243B2 (en) 2013-06-14 2017-04-11 Cardiothrive, Inc. Dynamically adjustable multiphasic defibrillator pulse system and method
US9907970B2 (en) 2013-06-14 2018-03-06 Cardiothrive, Inc. Therapeutic system and method using biphasic or multiphasic pulse waveform
US10279189B2 (en) 2013-06-14 2019-05-07 Cardiothrive, Inc. Wearable multiphasic cardioverter defibrillator system and method
US9833630B2 (en) 2013-06-14 2017-12-05 Cardiothrive, Inc. Biphasic or multiphasic pulse waveform and method
US9656094B2 (en) 2013-06-14 2017-05-23 Cardiothrive, Inc. Biphasic or multiphasic pulse generator and method
WO2014203911A1 (ja) 2013-06-18 2014-12-24 久光製薬株式会社 アプリケータ
US10039911B2 (en) 2013-06-19 2018-08-07 Hisamitsu Pharmaceutical Co., Inc. Applicator
US20150027241A1 (en) * 2013-07-23 2015-01-29 Diba Industries, Inc. Piercing probes with offset conical piercing tip and fluid-sampling systems comprising the piercing probes
WO2015059699A2 (en) 2013-10-23 2015-04-30 Valtech Cardio, Ltd. Anchor magazine
EP3082760A1 (de) 2013-12-19 2016-10-26 Novartis AG Leptin-mrna-zusammensetzungen und -formulierungen
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
GB201403773D0 (en) * 2014-03-04 2014-04-16 Univ Cardiff Microneedle based cell delivery
US10279106B1 (en) 2014-05-08 2019-05-07 Tandem Diabetes Care, Inc. Insulin patch pump
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
CN112237662B (zh) 2014-06-03 2022-10-21 安姆根有限公司 药物递送系统和使用方法
WO2015196085A2 (en) 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US10321858B2 (en) 2014-08-18 2019-06-18 Proteadx, Inc. Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
WO2016037127A1 (en) 2014-09-05 2016-03-10 C.R. Bard, Inc. Catheter insertion device including retractable needle
JP2017527394A (ja) * 2014-09-15 2017-09-21 サノフイ ベース上に回転可能なハウジングを有する薬剤送達デバイス
DE102014219719B4 (de) * 2014-09-29 2018-05-03 Ipr Intelligente Peripherien Für Roboter Gmbh Nadelgreifer
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
CN105873514B (zh) * 2014-10-27 2018-10-26 深圳市光聚通讯技术开发有限公司 动态血糖采集装置及主机
EP3848072A1 (de) 2014-12-19 2021-07-14 Amgen Inc. Medikamentenabgabevorrichtung mit näherungssensor
US11357916B2 (en) 2014-12-19 2022-06-14 Amgen Inc. Drug delivery device with live button or user interface field
CA2971853A1 (en) 2014-12-23 2016-06-30 Abraham Hasarchi Harmonizing noise aggregation and noise management in distributed antenna system
EP3045185A1 (de) * 2015-01-16 2016-07-20 Sanofi-Aventis Deutschland GmbH Konnektor für einen mit einem flüssigen arzneimittel gefüllten behälter
WO2016123406A1 (en) 2015-01-28 2016-08-04 Chrono Therapeutics Inc. Drug delivery methods and systems
CA2976935C (en) 2015-02-17 2020-03-10 Amgen Inc. Drug delivery device with vacuum assisted securement and/or feedback
BR112017019272A2 (pt) 2015-03-10 2018-05-02 Allergan Pharmaceuticals Holdings Ireland Unlimited Company injetor de múltiplas agulhas
EP3267875A4 (de) 2015-03-12 2018-12-05 Chrono Therapeutics Inc. Eingabe- und unterstützungssystem für heftiges verlangen
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
USD903100S1 (en) 2015-05-01 2020-11-24 C. R. Bard, Inc. Catheter placement device
JP6784352B2 (ja) * 2015-05-11 2020-11-11 国立大学法人 東京医科歯科大学 インスリン送達用デバイス
WO2016187037A1 (en) 2015-05-15 2016-11-24 C.R.Bard, Inc. Catheter placement device including an extensible needle safety component
US10463847B2 (en) 2015-06-11 2019-11-05 Steadymed Ltd. Infusion set
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10940292B2 (en) 2015-07-08 2021-03-09 Actuated Medical, Inc. Reduced force device for intravascular access and guidewire placement
US11793543B2 (en) 2015-09-18 2023-10-24 Obvius Robotics, Inc. Device and method for automated insertion of penetrating member
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
WO2017139375A1 (en) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
JP7202890B2 (ja) * 2016-02-19 2023-01-12 ノース カロライナ ステート ユニバーシティ 生理学的応答性マイクロニードル送達システムに関連する方法及び組成物
NZ747635A (en) 2016-03-28 2024-05-31 Ichor Medical Systems Inc Method and apparatus for delivery of therapeutic agents
US10596321B2 (en) 2016-04-08 2020-03-24 Allergan, Inc. Aspiration and injection device
WO2017192565A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
US20200306518A1 (en) * 2016-05-20 2020-10-01 Uprax Microsolutions B.V. System and method for applying microneedles
NL2016807B1 (en) * 2016-05-20 2017-11-27 Uprax System and method for applying microneedles
US10220195B2 (en) * 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
CN109715093B (zh) 2016-09-12 2020-11-06 C·R·巴德股份有限公司 导管插入装置的血液控制
US11241563B2 (en) 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
EP3338832A1 (de) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medikamentenverabreichungsvorrichtung
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11400260B2 (en) 2017-03-01 2022-08-02 C. R. Bard, Inc. Catheter insertion device
US12109032B1 (en) 2017-03-11 2024-10-08 Biolinq Incorporated Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
AU2018251786B2 (en) 2017-04-13 2020-08-27 Teleflex Medical Llc Catheter insertion device
US11045142B1 (en) 2017-04-29 2021-06-29 Biolinq, Inc. Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
US12599337B1 (en) 2017-08-08 2026-04-14 Biolinq Incorporated Method and system for confirmation of microneedle-based analyte-selective sensor insertion into viable tissue via electrical interrogation
CN109833562B (zh) * 2017-11-27 2024-03-15 苏州纳通生物纳米技术有限公司 一种一次性自毁式振动头组件以及应用该组件的促渗仪
US10828500B2 (en) 2017-12-22 2020-11-10 Cardiothrive, Inc. External defibrillator
EP3735285A4 (de) * 2018-01-07 2021-10-27 Avraham Amir Hochlast-mikronadeln und zusammensetzungen zur hautaugmentation
CN115671504A (zh) 2018-03-07 2023-02-03 巴德阿克塞斯系统股份有限公司 用于医疗装置插入系统的导丝推进和血液闪回系统
US11090506B2 (en) * 2018-05-15 2021-08-17 Omm Imports, Inc. Disposable product cap and assembly having a manually usable thermo-optical device for skin care
CA3101966A1 (en) 2018-05-29 2019-12-05 Morningside Venture Investments Limited Drug delivery methods and systems
CN112312892B (zh) * 2018-06-29 2025-05-02 强生消费者公司 用于递送活性物质的三维微流体装置
USD921884S1 (en) 2018-07-27 2021-06-08 Bard Access Systems, Inc. Catheter insertion device
FR3084578B1 (fr) * 2018-08-03 2024-01-12 Pkvitality Gestion enfoncement de microaiguilles
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
CA3208266C (en) 2019-02-22 2024-04-16 Deka Products Limited Partnership Infusion set and inserter assembly systems and methods
US12539361B2 (en) 2019-02-22 2026-02-03 Deka Products Limited Partnership Infusion set and inserter assembly apparatuses, systems, and methods
WO2020188484A1 (en) * 2019-03-19 2020-09-24 King Abdullah University Of Science And Technology Miniaturized delivery system and method
US11590332B2 (en) * 2019-04-17 2023-02-28 Path Scientific, Llc Precision microneedling device and methods of use
JP2022532215A (ja) 2019-05-16 2022-07-13 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 皮膚および非皮膚薬物送達のためのアンダーカット特徴を有するマイクロニードルアレイ
GB201908043D0 (en) * 2019-06-05 2019-07-17 Lekkos Vasileios Transdermal patch for therapeutic uses
KR102279603B1 (ko) * 2019-06-11 2021-07-20 (주)비올 바늘 조립체, 이를 포함하는 피부 자극기 및 그 제조 방법
WO2021009559A1 (en) * 2019-07-12 2021-01-21 Qulab Medical Ltd. Electrochemical fet sensor
WO2021020730A2 (ko) * 2019-07-26 2021-02-04 주식회사 림사이언스 의료용 니들을 가압하는 장치
CN213312819U (zh) 2019-08-19 2021-06-01 贝克顿·迪金森公司 中线导管放置装置
WO2021054980A1 (en) 2019-09-20 2021-03-25 Bard Peripheral Vascular, Inc. Intravenous catheter-placement device
WO2021087249A1 (en) * 2019-10-30 2021-05-06 Thermalin, Inc. Agent delivery systems, devices, and methods
US20230191099A1 (en) * 2020-02-20 2023-06-22 Jubilee Biotech Co., Ltd. Applicator for drug delivery and microneedle patch used therefor
US20220031244A1 (en) 2020-07-29 2022-02-03 Biolinq Inc. Continuous analyte monitoring system with microneedle array
CN112370653B (zh) * 2020-11-12 2022-08-30 深圳市圣通生物科技有限公司 一种喷淋消毒式纳米微针中胚层导入美容仪
DE102020129916A1 (de) * 2020-11-12 2022-05-12 Lts Lohmann Therapie-Systeme Ag. Interdermales Wirkstoffabgabesystem
US20220273352A1 (en) * 2021-03-01 2022-09-01 Bluexthermal, Inc. Device and method for thermal modulation of tissue
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
EP4153276B1 (de) 2021-05-08 2025-12-10 Biolinq Incorporated Fehlererkennung für eine auf mikronadelarrays basierende kontinuierliche analytüberwachungsvorrichtung
US12059371B2 (en) 2022-01-04 2024-08-13 Bluexthermal, Inc. Ocular region heat transfer devices and associated systems and methods
CN115177258B (zh) * 2022-06-07 2024-08-20 东华大学 一种自锁导电心肌补片及其制备方法
EP4295873A1 (de) * 2022-06-21 2023-12-27 National University of Ireland Galway Infusionskathetersystem
EP4658168A2 (de) 2023-02-02 2025-12-10 Biolinq, Inc. Verfahren zur verbesserten sensorempfindlichkeit eines kontinuierlichen analytüberwachungssystems auf mikronadelbasis
US12426965B2 (en) 2023-06-15 2025-09-30 Obvius Robotics, Inc. Image-guided robotic arm for inserting a penetrating member into a body lumen

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US447225A (en) * 1891-02-24 Machine for attaching stays to the corners of boxes
US3659A (en) * 1844-07-11 Machine for hulling and pearling rice
US3537A (en) 1844-04-13 X g gupping instrument
US1934043A (en) * 1929-05-17 1933-11-07 Standard Oil Dev Co Process of improvement of lubricating oils
DE596981C (de) 1931-10-30 1934-05-12 Mario Demarchi Dr Injektionsspritze
FR757501A (fr) 1932-09-23 1933-12-28 Dispositif automatique pour la manceuvre des seringues d'injection
US2088780A (en) 1936-10-09 1937-08-03 Sigurd E Follese Massage device
US2763935A (en) 1954-06-11 1956-09-25 Purdne Res Foundation Determining depth of layers of fat and of muscle on an animal body
US2945496A (en) 1958-08-18 1960-07-19 Fosdal Alfred Dental instrument for immobilizing tissue
DE1115722B (de) 1960-04-30 1961-10-26 Hoechst Ag Metallanode fuer die elektrolytische Abscheidung von Chlor
GB1128329A (en) 1964-12-23 1968-09-25 Nat Res Dev Electrodes for making electrical contact to the living body of a mammal
US3568735A (en) * 1968-06-26 1971-03-09 Cooke Eng Co Laboratory microtitration dispensing apparatus
US3568732A (en) 1969-02-28 1971-03-09 Kelly James A Jun Splice straightener for aerial conductors
US3659600A (en) 1970-02-24 1972-05-02 Estin Hans H Magnetically operated capsule for administering drugs
US3727614A (en) 1971-05-13 1973-04-17 Merck & Co Inc Multiple dosage inoculator
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3738493A (en) 1971-09-24 1973-06-12 Analytical Instr Spec Apparatus for simultaneous application of samples to thin layer chromatography plates
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
CH557178A (de) 1972-08-10 1974-12-31 Siemens Ag Geraet fuer die zufuehrung von medikamenten.
US3923060A (en) 1974-04-23 1975-12-02 Jr Everett H Ellinwood Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means
US4140109A (en) 1977-10-17 1979-02-20 Savic Michael I Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery
FR2460343A1 (fr) 1979-06-29 1981-01-23 Solvay Cathode pour la production electrolytique d'hydrogene
JPS5683360A (en) * 1979-12-10 1981-07-07 Olympus Optical Co Pneumoperitoneum needle
US4447225A (en) 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
US4619652A (en) 1982-12-23 1986-10-28 Alza Corporation Dosage form for use in a body mounted pump
US4505710A (en) 1983-05-13 1985-03-19 Collins Earl R Implantable fluid dispensing system
DE3502913C1 (de) 1985-01-29 1986-07-03 Günter Prof. Dr.rer.nat. 5100 Aachen Rau Messaufnehmer zur nichtinvasiven Erfassung elektrophysiologischer Groessen
US4777599A (en) 1985-02-26 1988-10-11 Gillette Company Viscoelastometry of skin using shear wave propagation
FR2594341B1 (fr) * 1986-02-14 1990-08-10 Charton Jean Pierre Appareil injecteur pour la pratique de la mesotherapie
AT384737B (de) 1986-04-04 1987-12-28 Thoma Dipl Ing Dr Techn Herwig Vorrichtung zur stroemungskonstanten abgabe fluessiger arzneimittel
EP0260953B1 (de) * 1986-09-18 1994-03-30 Paul G. Yock Vorrichtung für Anwendung in der Kanalisation von Blutgefässen
US4886499A (en) 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
US4808156A (en) 1987-03-09 1989-02-28 Dean Consuelo M Cannular instrument and method for inserting a cannular instrument into a vein
US6056716A (en) 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
DD262803A1 (de) 1987-08-05 1988-12-14 Transform Roentgen Matern Veb Injektionseinrichtung
US5312486A (en) 1987-12-24 1994-05-17 Frank Meyer Water-containing, hardenable foam compositions with inorganic components and process for their preparation
US4989614A (en) 1988-02-23 1991-02-05 Vance Products Incorporated Fine-needle aspiration cell sampling methods
CA2008262A1 (en) * 1989-01-30 1990-07-30 John A. Gilly Clinical applicator
US5062834A (en) 1989-02-24 1991-11-05 Product Development (S.G.Z.) Ltd Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate
US5425706A (en) 1989-02-24 1995-06-20 S. I. Scientific Innovations Ltd. Dispensing device particularly useful for dispensing nutritional liquids
JPH0648975B2 (ja) 1989-10-02 1994-06-29 俊郎 樋口 微小インジェクション装置及びそのインジェクション制御方法
US5262128A (en) 1989-10-23 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Array-type multiple cell injector
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US6090790A (en) 1989-12-14 2000-07-18 Eriksson; Elof Gene delivery by microneedle injection
US5697901A (en) 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
US5092901A (en) 1990-06-06 1992-03-03 The Royal Institution For The Advancement Of Learning (Mcgill University) Shape memory alloy fibers having rapid twitch response
US5156591A (en) 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
TW279133B (de) 1990-12-13 1996-06-21 Elan Med Tech
US5279547A (en) 1991-01-03 1994-01-18 Alcon Surgical Inc. Computer controlled smart phacoemulsification method and apparatus
SE9101022D0 (sv) * 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5312456A (en) 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
ATE155045T1 (de) 1991-11-13 1997-07-15 Elan Corp Plc Vorrichtung zur verabreichung von heilmitteln
US6048337A (en) 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
JP2547520B2 (ja) 1992-01-21 1996-10-23 ヴァリーラブ・インコーポレーテッド トロカールのための電気外科的制御器
US5252023A (en) * 1992-02-10 1993-10-12 Kelly Kevin M Lifting apparatus
JP2572823Y2 (ja) 1992-02-13 1998-05-25 株式会社アドバンス 簡易採血器
AU4282793A (en) 1992-04-10 1993-11-18 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University A microneedle for injection of ocular blood vessels
US5478328A (en) 1992-05-22 1995-12-26 Silverman; David G. Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method
JPH0698920A (ja) * 1992-09-21 1994-04-12 Hayashi Shigetada 鍼灸精密測定器
US5354273A (en) 1992-12-14 1994-10-11 Mallinckrodt Medical, Inc. Delivery apparatus with pressure controlled delivery
US5478323A (en) 1993-04-02 1995-12-26 Eli Lilly And Company Manifold for injection apparatus
IE68890B1 (en) 1993-04-08 1996-07-24 Elan Med Tech Intradermal delivery device
US5335668A (en) * 1993-04-30 1994-08-09 Medical Scientific, Inc. Diagnostic impedance measuring system for an insufflation needle
JP3494183B2 (ja) * 1993-08-10 2004-02-03 株式会社アドバンス 簡易採血装置
WO1995007722A1 (en) 1993-09-14 1995-03-23 North Shore Laboratories Pty. Ltd. Injection device
US5389222A (en) 1993-09-21 1995-02-14 The United States Of America As Represented By The United States Department Of Energy Spring-loaded polymeric gel actuators
US5599346A (en) 1993-11-08 1997-02-04 Zomed International, Inc. RF treatment system
US5997501A (en) 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
CA2149836C (en) 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration
US5611806A (en) 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
US5649423A (en) 1994-06-07 1997-07-22 Sandia Corporation Micromechanism linear actuator with capillary force sealing
DE4420232A1 (de) 1994-06-07 1995-12-14 Robert Waltereit Vorrichtung zur Prüfung der Eindringtiefe einer Kanüle oder Sonde in den Körper eines Patienten
US5478315A (en) 1994-08-08 1995-12-26 Brothers Family Investments, L.C. Local anesthetic injection system
US5432098A (en) 1994-10-31 1995-07-11 Dynatech Precision Sampling Corporation Apparatus, and process, for automatically sampling solids and semi-solids materials for analysis
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
GB9508606D0 (en) 1995-04-27 1995-06-14 Svedman Paul Suction blister sampling
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
US5827216A (en) 1995-06-07 1998-10-27 Cormedics Corp. Method and apparatus for accessing the pericardial space
ZA9610374B (en) * 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
JPH09192218A (ja) * 1996-01-16 1997-07-29 Hitachi Ltd 血糖値管理システム
JPH09239031A (ja) * 1996-03-09 1997-09-16 Honda Electron Co Ltd 超音波振動子を装着した注射器
US5843016A (en) 1996-03-18 1998-12-01 Physion S.R.L. Electromotive drug administration for treatment of acute urinary outflow obstruction
US6117155A (en) 1996-05-01 2000-09-12 Lee; Young H. Coated needle for use with an intramuscular stimulation treatment device
US5785688A (en) 1996-05-07 1998-07-28 Ceramatec, Inc. Fluid delivery apparatus and method
US5954668A (en) 1996-06-14 1999-09-21 Medrad, Inc. Extravasation detector using microwave radiometry
US7184826B2 (en) 1996-06-18 2007-02-27 Alza Corporation Device and method for enhancing transdermal flux of agents being delivered or sampled
ES2200187T3 (es) 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
JPH1043296A (ja) * 1996-08-05 1998-02-17 Terumo Corp 薬液注入器具
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
US6071251A (en) 1996-12-06 2000-06-06 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
SE9604564D0 (sv) 1996-12-12 1996-12-12 Paal Svedman Sätt och anordning vid avledning av elektriska strömmar
US6246904B1 (en) 1996-12-17 2001-06-12 Alza Corporation Electrotransport drug delivery reservoirs containing inert fillers
US5928194A (en) 1997-04-07 1999-07-27 Maget; Henri J. R. Self-contained liquid microdispenser
US5928207A (en) 1997-06-30 1999-07-27 The Regents Of The University Of California Microneedle with isotropically etched tip, and method of fabricating such a device
US5972013A (en) 1997-09-19 1999-10-26 Comedicus Incorporated Direct pericardial access device with deflecting mechanism and method
JPH11137684A (ja) * 1997-11-12 1999-05-25 Hiroshi Oya 無痛安全注射器
AU752222B2 (en) * 1997-11-26 2002-09-12 E-Z-Em, Inc. Extravasation detection technique
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
WO1999029364A1 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
PT1037686E (pt) 1997-12-11 2005-10-31 Alza Corp Aparelho para potenciar o fluxo de agente transdermico
US6126629A (en) 1997-12-18 2000-10-03 Bausch & Lomb Surgical, Inc. Multiple port phaco needle
US6154673A (en) * 1997-12-30 2000-11-28 Agilent Technologies, Inc. Multilingual defibrillator
US6048204A (en) * 1998-02-03 2000-04-11 Lifecore Biomedical, Inc. Self tapping screw type dental implant
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US6391005B1 (en) * 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US5971998A (en) 1998-03-31 1999-10-26 Donald G. Russell Support device and method for controlling breast thickness during stereotactic guided needle biopsy
WO1999058051A1 (en) 1998-05-13 1999-11-18 Cygnus, Inc. Monitoring of physiological analytes
ATE258028T1 (de) 1998-05-13 2004-02-15 Cygnus Therapeutic Systems Signalverarbeitung zur messung von physiologischen analyten
EP1082151A1 (de) 1998-06-04 2001-03-14 ELAN CORPORATION, Plc Gasbetriebene medikamentenabgabevorrichtung
AU767122B2 (en) 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6678556B1 (en) 1998-07-13 2004-01-13 Genetronics, Inc. Electrical field therapy with reduced histopathological change in muscle
GB9815819D0 (en) 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
GB9815820D0 (en) 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
US6123684A (en) 1998-07-27 2000-09-26 Medi-Ject Corporation Loading mechanism for medical injector assembly
CA2344398A1 (en) 1998-09-18 2000-03-30 The University Of Utah Surface micromachined microneedles
DE19843733A1 (de) * 1998-09-24 2000-03-30 Voith Sulzer Papiertech Patent Rakelvorrichtung
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6317630B1 (en) 1999-01-29 2001-11-13 Yossi Gross Drug delivery device
US6132449A (en) 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
US6319230B1 (en) 1999-05-07 2001-11-20 Scimed Life Systems, Inc. Lateral needle injection apparatus and method
US6689103B1 (en) 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
CA2376128C (en) 1999-06-04 2009-01-06 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
EP1196079A1 (de) 1999-06-18 2002-04-17 The University Of Virginia Patent Foundation Gerät und verfahren zum flüssigkeitstransport
US6408204B1 (en) 1999-07-28 2002-06-18 Medrad, Inc. Apparatuses and methods for extravasation detection
ES2248165T3 (es) * 1999-11-15 2006-03-16 Velcro Industries B.V. Elemento de fijacion a la piel.
CA2394171A1 (en) * 1999-12-16 2001-06-21 Alza Corporation Device for enhancing transdermal flux of sampled agents
US7003336B2 (en) * 2000-02-10 2006-02-21 Medtronic Minimed, Inc. Analyte sensor method of making the same
US6572740B2 (en) 2000-04-13 2003-06-03 Elan Pharma International Limited Electrolytic cell
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
JP2002028247A (ja) * 2000-07-18 2002-01-29 Japan Science & Technology Corp 穿刺針による静脈刺入の感知方法及び装置
US6939324B2 (en) 2000-11-30 2005-09-06 Biovalve Technologies, Inc. Fluid delivery and measurement systems and methods
JP2004528151A (ja) 2001-06-11 2004-09-16 グラクソ　グループ　リミテッド 薬剤ディスペンサ
US6835193B2 (en) 2001-07-10 2004-12-28 Myocardial Therapeutics, Inc. Methods for controlled depth injections into interior body cavities
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
AU2002360712A1 (en) * 2001-12-21 2003-07-30 The Trustees Of Columbia University In The City Of New York C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis
EP1403519A1 (de) * 2002-09-27 2004-03-31 Novo Nordisk A/S Membranpumpe mit dehnbarer Pumpenmembran

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