ATE38667T1 - 2-arylmethyl-5-aryl-oxazolidine, ihre herstellung und ihre verwendung. - Google Patents

2-arylmethyl-5-aryl-oxazolidine, ihre herstellung und ihre verwendung.

Info

Publication number: ATE38667T1
Authority: AT; Austria
Prior art keywords: oxazolidines; arylmethyl; aryl; preparation; fenoldopam
Prior art date: 1984-10-05

Application number

AT85306991T

Other languages

English (en)

Inventor

Clifford Steven Labaw

Alan William Tremper

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-05

Filing date

1985-10-01

Publication date

1988-12-15

1985-10-01 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1988-12-15 Application granted granted Critical

1988-12-15 Publication of ATE38667T1 publication Critical patent/ATE38667T1/de

Links

229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
229940005501 dopaminergic agent Drugs 0.000 abstract 1
230000003291 dopaminomimetic effect Effects 0.000 abstract 1
TVURRHSHRRELCG-UHFFFAOYSA-N fenoldopam Chemical compound C1=CC(O)=CC=C1C1C2=CC(O)=C(O)C(Cl)=C2CCNC1 TVURRHSHRRELCG-UHFFFAOYSA-N 0.000 abstract 1
229960002724 fenoldopam Drugs 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)

AT85306991T 1984-10-05 1985-10-01 2-arylmethyl-5-aryl-oxazolidine, ihre herstellung und ihre verwendung. ATE38667T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US65790484A	1984-10-05	1984-10-05
EP85306991A EP0177326B1 (de)	1984-10-05	1985-10-01	2-Arylmethyl-5-aryl-oxazolidine, ihre Herstellung und ihre Verwendung

Publications (1)

Publication Number	Publication Date
ATE38667T1 true ATE38667T1 (de)	1988-12-15

Family

ID=24639125

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85306991T ATE38667T1 (de)	1984-10-05	1985-10-01	2-arylmethyl-5-aryl-oxazolidine, ihre herstellung und ihre verwendung.

Country Status (4)

Country	Link
EP (1)	EP0177326B1 (de)
JP (1)	JPS6191179A (de)
AT (1)	ATE38667T1 (de)
DE (1)	DE3566255D1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2134870T3 (es) *	1993-05-01	1999-10-16	Merck Patent Gmbh	Antagonistas del receptor de adhesion.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4197297A (en) *	1976-11-17	1980-04-08	Smithkline Corporation	6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines

1985
- 1985-10-01 EP EP85306991A patent/EP0177326B1/de not_active Expired
- 1985-10-01 DE DE8585306991T patent/DE3566255D1/de not_active Expired
- 1985-10-01 AT AT85306991T patent/ATE38667T1/de not_active IP Right Cessation
- 1985-10-04 JP JP60222618A patent/JPS6191179A/ja active Pending

Also Published As

Publication number	Publication date
EP0177326A2 (de)	1986-04-09
EP0177326B1 (de)	1988-11-17
EP0177326A3 (en)	1987-01-07
DE3566255D1 (en)	1988-12-22
JPS6191179A (ja)	1986-05-09

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Legal Events

Date	Code	Title	Description
1989-03-15	UEP	Publication of translation of european patent specification
2006-01-15	EELA	Cancelled due to lapse of time