ATE386821T1 - COMPOSITIONS AND METHODS FOR DETECTING HUMAN IMMUNODEFICIENCY VIRUS 2 (HIV-2) - Google Patents
COMPOSITIONS AND METHODS FOR DETECTING HUMAN IMMUNODEFICIENCY VIRUS 2 (HIV-2)Info
- Publication number
- ATE386821T1 ATE386821T1 AT01988788T AT01988788T ATE386821T1 AT E386821 T1 ATE386821 T1 AT E386821T1 AT 01988788 T AT01988788 T AT 01988788T AT 01988788 T AT01988788 T AT 01988788T AT E386821 T1 ATE386821 T1 AT E386821T1
- Authority
- AT
- Austria
- Prior art keywords
- hiv
- compositions
- methods
- immunodeficiency virus
- human immunodeficiency
- Prior art date
Links
- 241000713340 Human immunodeficiency virus 2 Species 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 2
- 108091093088 Amplicon Proteins 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- AIDS & HIV (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Compositions and methods for synthesizing and detecting HIV-2 specific amplicons. Particularly described are oligonucleotides that are useful as hybridization probes, and amplification primers that facilitate detection of very low levels of HIV-2 nucleic acids.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24262000P | 2000-10-23 | 2000-10-23 | |
| US28005801P | 2001-03-30 | 2001-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE386821T1 true ATE386821T1 (en) | 2008-03-15 |
Family
ID=26935205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01988788T ATE386821T1 (en) | 2000-10-23 | 2001-10-22 | COMPOSITIONS AND METHODS FOR DETECTING HUMAN IMMUNODEFICIENCY VIRUS 2 (HIV-2) |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6870045B2 (en) |
| EP (1) | EP1399585B1 (en) |
| JP (1) | JP4202750B2 (en) |
| AT (1) | ATE386821T1 (en) |
| AU (2) | AU2002230545B2 (en) |
| CA (1) | CA2422956C (en) |
| DE (1) | DE60132924T2 (en) |
| ES (1) | ES2300375T3 (en) |
| WO (1) | WO2002034951A2 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2860006B1 (en) * | 2003-09-24 | 2006-12-22 | Commissariat Energie Atomique | DEVICE FOR SEPARATING AND / OR ANALYZING MULTIPLE MOLECULAR TARGETS IN SOLUTION IN A COMPLEX MIXTURE |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| KR100924243B1 (en) * | 2007-11-19 | 2009-10-29 | (주)바이오메트릭스 테크놀로지 | Novel method of designing dna probe chip for room temperature hybridization and the dna probe chip |
| AU2009262870B2 (en) | 2008-05-30 | 2014-03-20 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Salmonella |
| EP2172563A1 (en) * | 2008-09-24 | 2010-04-07 | bioMérieux S.A. | Method for lowering the dependency towards sequence variation of a nucleic acid target in a diagnostic hybridization assay |
| EP2459743B1 (en) | 2009-07-30 | 2017-09-13 | Roche Diagnostics GmbH | A set of oligonucleotide probes as well as methods and uses related thereto |
| JP2013503352A (en) | 2009-08-31 | 2013-01-31 | エムバイオ ダイアグノスティクス,インコーポレイティド | Integrated sample preparation and analyte detection |
| EP2550362B1 (en) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
| DE102010003781B4 (en) * | 2010-04-08 | 2012-08-16 | Aj Innuscreen Gmbh | Method for detecting specific nucleic acid sequences |
| CA2832109C (en) | 2011-06-10 | 2021-07-06 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| EP2568289A3 (en) | 2011-09-12 | 2013-04-03 | International AIDS Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| US9127317B2 (en) * | 2012-03-02 | 2015-09-08 | Winthrop-University Hospital | Method for using probe based PCR detection to measure the levels of circulating demethylated β cell derived DNA as a measure of β cell loss in diabetes |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| CN103966355A (en) * | 2013-01-25 | 2014-08-06 | 上海星耀医学科技发展有限公司 | Human immunodeficiency virus type 1 one-step genotyping RT-PCR detection kit |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| EP3072901A1 (en) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| CN112359146A (en) * | 2020-11-30 | 2021-02-12 | 浙江大学 | Kit for rapidly detecting hepatitis B virus gene and detection method thereof |
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| US5176995A (en) | 1985-03-28 | 1993-01-05 | Hoffmann-La Roche Inc. | Detection of viruses by amplification and hybridization |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US5008182A (en) | 1986-01-10 | 1991-04-16 | Cetus Corporation | Detection of AIDS associated virus by polymerase chain reaction |
| US4868105A (en) | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| AU601397B2 (en) | 1986-01-22 | 1990-09-13 | Institut Pasteur | Retrovirus of the hiv-2 type susceptible of inducing aids, and its antigenic and nucleic constituents |
| US5310651A (en) | 1986-01-22 | 1994-05-10 | Institut Pasteur | DNA probes of human immunodeficiency virus type 2 (HIV-2), and methods employing these probes for dectecting the presence of HIV-2 |
| US5066782A (en) | 1986-01-22 | 1991-11-19 | Institut Pasteur | Retrovirus capable of causing AIDS, means and method for detecting it in vitro |
| ATE88762T1 (en) | 1986-08-11 | 1993-05-15 | Siska Diagnostics Inc | METHODS AND COMPOSITIONS FOR TESTING WITH NUCLEIC ACID PROBES. |
| US5541308A (en) | 1986-11-24 | 1996-07-30 | Gen-Probe Incorporated | Nucleic acid probes for detection and/or quantitation of non-viral organisms |
| DE3856595D1 (en) | 1987-01-16 | 2009-01-22 | Pasteur Institut | HIV-2 and SIV-1 nucleotide sequences |
| IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Method and kits for the amplification and detection of nucleic acid sequences |
| CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
| US5639604A (en) | 1987-09-21 | 1997-06-17 | Gen-Probe Incorporated | Homogeneous protection assay |
| US5283174A (en) | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| CA1340747C (en) | 1988-06-14 | 1999-09-14 | Karsten Henco | Hiv-2 virus variants |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| JP3276955B2 (en) | 1988-09-30 | 2002-04-22 | ジーン−トラック・システムス | Probe structure bound to end of RNA template and method of using the same |
| US5223423A (en) | 1989-03-31 | 1993-06-29 | United States Of America | Characterization of replication competent human immunodeficiency type 2 proviral clone hiv-2sbl/isy |
| EP1715064B1 (en) | 1989-06-02 | 2009-02-25 | Institut Pasteur | Nucleotide sequences derived from the genomes of the retroviruses HIV-1, HIV-2 and SIV, and their application to the amplification of pol sequences in these viral genomes and to the in vitro diagnosis of infections resulting from these viruses |
| FR2647810B1 (en) | 1989-06-02 | 1994-07-22 | Pasteur Institut | OLIGONUCLEOTIDE PRIMERS FOR THE AMPLIFICATION OF THE GENOME OF HIV-2 AND SIV RETROVIRUSES, AND THEIR APPLICATIONS TO THE IN VITRO DIAGNOSIS OF INFECTIONS DUE TO THESE VIRUSES |
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-
2001
- 2001-10-22 AT AT01988788T patent/ATE386821T1/en not_active IP Right Cessation
- 2001-10-22 DE DE60132924T patent/DE60132924T2/en not_active Expired - Lifetime
- 2001-10-22 AU AU2002230545A patent/AU2002230545B2/en not_active Expired
- 2001-10-22 ES ES01988788T patent/ES2300375T3/en not_active Expired - Lifetime
- 2001-10-22 US US10/001,407 patent/US6870045B2/en not_active Expired - Lifetime
- 2001-10-22 WO PCT/US2001/045396 patent/WO2002034951A2/en not_active Ceased
- 2001-10-22 AU AU3054502A patent/AU3054502A/en active Pending
- 2001-10-22 EP EP01988788A patent/EP1399585B1/en not_active Expired - Lifetime
- 2001-10-22 CA CA2422956A patent/CA2422956C/en not_active Expired - Lifetime
- 2001-10-22 JP JP2002537919A patent/JP4202750B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004518416A (en) | 2004-06-24 |
| AU2002230545C1 (en) | 2002-05-06 |
| CA2422956C (en) | 2010-10-19 |
| AU2002230545B2 (en) | 2006-09-21 |
| DE60132924D1 (en) | 2008-04-03 |
| US20020177127A1 (en) | 2002-11-28 |
| JP4202750B2 (en) | 2008-12-24 |
| WO2002034951A3 (en) | 2003-12-24 |
| EP1399585B1 (en) | 2008-02-20 |
| CA2422956A1 (en) | 2002-05-02 |
| AU3054502A (en) | 2002-05-06 |
| ES2300375T3 (en) | 2008-06-16 |
| WO2002034951A2 (en) | 2002-05-02 |
| EP1399585A2 (en) | 2004-03-24 |
| US6870045B2 (en) | 2005-03-22 |
| DE60132924T2 (en) | 2009-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1399585 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |