ATE389634T1 - Den vanilliod-trpv1-rezeptor antagonisierende sulfonamidoverbindungen - Google Patents

Den vanilliod-trpv1-rezeptor antagonisierende sulfonamidoverbindungen

Info

Publication number
ATE389634T1
ATE389634T1 AT05796943T AT05796943T ATE389634T1 AT E389634 T1 ATE389634 T1 AT E389634T1 AT 05796943 T AT05796943 T AT 05796943T AT 05796943 T AT05796943 T AT 05796943T AT E389634 T1 ATE389634 T1 AT E389634T1
Authority
AT
Austria
Prior art keywords
vanilliod
sulfonamid
trpv1 receptor
compounds
compounds antagonizing
Prior art date
Application number
AT05796943T
Other languages
English (en)
Inventor
Pier Giovanni Baraldi
Pier Andrea Borea
Pierangelo Geppetti
Original Assignee
Pharmeste Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmeste Srl filed Critical Pharmeste Srl
Application granted granted Critical
Publication of ATE389634T1 publication Critical patent/ATE389634T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/18Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/47Y being a hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/06Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT05796943T 2004-10-26 2005-10-18 Den vanilliod-trpv1-rezeptor antagonisierende sulfonamidoverbindungen ATE389634T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002042A ITMI20042042A1 (it) 2004-10-26 2004-10-26 Derivati solfonammidici antagonisti del recettore dei vanilloidi trpv1

Publications (1)

Publication Number Publication Date
ATE389634T1 true ATE389634T1 (de) 2008-04-15

Family

ID=35501228

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05796943T ATE389634T1 (de) 2004-10-26 2005-10-18 Den vanilliod-trpv1-rezeptor antagonisierende sulfonamidoverbindungen

Country Status (8)

Country Link
US (1) US7579378B2 (de)
EP (1) EP1805138B1 (de)
JP (1) JP5080260B2 (de)
AT (1) ATE389634T1 (de)
DE (1) DE602005005512T2 (de)
ES (1) ES2303275T3 (de)
IT (1) ITMI20042042A1 (de)
WO (1) WO2006045498A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1861357B1 (de) * 2005-03-19 2013-04-24 Amorepacific Corporation Neue verbindungen oder pharmazeutisch unbedenkliche salze davon als vanilloidrezeptorantagonist, und pharmazeutische zusammensetzungen, die diese enthalten
WO2009081222A1 (en) 2007-12-21 2009-07-02 Glenmark Pharmaceuticals, S.A. Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands
CN106146362B (zh) * 2015-04-15 2018-04-03 南京理工大学 一种合成c‑7280948的方法
CN107759477A (zh) * 2017-11-20 2018-03-06 阿里化学(常州)有限公司 一种对硝基苯乙胺盐酸盐的生产制备方法
EP4074317A1 (de) 2021-04-14 2022-10-19 Bayer AG Phosphorderivate als neuartige sos1-inhibitoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665675A (en) 1994-07-21 1997-09-09 Nippon Paper Industries Co., Ltd. Aminobenzenesulfonamide derivative and recording medium using the same
JP2004506714A (ja) * 2000-08-21 2004-03-04 パシフィック コーポレーション 新規チオ尿素化合物及びこれを含有する薬学的組成物
KR100564902B1 (ko) 2000-08-21 2006-03-30 주식회사 태평양 신규 티오우레아 유도체 및 이를 함유하는 약제학적 조성물
WO2002070467A1 (en) * 2001-02-26 2002-09-12 4Sc Ag Derivatives of diphenylurea, diphenyloxalic acid diamide and diphenylsulfuric acid diamide and their use as medicaments

Also Published As

Publication number Publication date
JP5080260B2 (ja) 2012-11-21
EP1805138B1 (de) 2008-03-19
DE602005005512D1 (de) 2008-04-30
US7579378B2 (en) 2009-08-25
JP2008517884A (ja) 2008-05-29
WO2006045498A1 (en) 2006-05-04
DE602005005512T2 (de) 2009-04-16
US20090118374A1 (en) 2009-05-07
ES2303275T3 (es) 2008-08-01
ITMI20042042A1 (it) 2005-01-26
EP1805138A1 (de) 2007-07-11

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Legal Events

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