ATE389669T1 - Genetisch-enkodierte bioindikatoren von kalziumionen - Google Patents
Genetisch-enkodierte bioindikatoren von kalziumionenInfo
- Publication number
- ATE389669T1 ATE389669T1 AT03016691T AT03016691T ATE389669T1 AT E389669 T1 ATE389669 T1 AT E389669T1 AT 03016691 T AT03016691 T AT 03016691T AT 03016691 T AT03016691 T AT 03016691T AT E389669 T1 ATE389669 T1 AT E389669T1
- Authority
- AT
- Austria
- Prior art keywords
- troponin
- calcium
- bioindicators
- calcium ion
- genetically encoded
- Prior art date
Links
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 title 1
- 239000000090 biomarker Substances 0.000 title 1
- 229910001424 calcium ion Inorganic materials 0.000 title 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 4
- 229910052791 calcium Inorganic materials 0.000 abstract 4
- 239000011575 calcium Substances 0.000 abstract 4
- 108090000362 Lymphotoxin-beta Proteins 0.000 abstract 3
- 102000013534 Troponin C Human genes 0.000 abstract 3
- 230000001413 cellular effect Effects 0.000 abstract 2
- 238000002866 fluorescence resonance energy transfer Methods 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4716—Muscle proteins, e.g. myosin, actin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03016691A EP1505073B1 (de) | 2003-08-04 | 2003-08-04 | Genetisch-enkodierte Bioindikatoren von Kalziumionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE389669T1 true ATE389669T1 (de) | 2008-04-15 |
Family
ID=33547606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03016691T ATE389669T1 (de) | 2003-08-04 | 2003-08-04 | Genetisch-enkodierte bioindikatoren von kalziumionen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090035788A1 (de) |
| EP (1) | EP1505073B1 (de) |
| AT (1) | ATE389669T1 (de) |
| DE (1) | DE60319817T2 (de) |
| WO (1) | WO2005014636A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110154515A1 (en) * | 2007-08-24 | 2011-06-23 | Oliver Griesbeck | Genetically encoded calcium sensors comprising the c-terminal lobe of troponin c and a fluorescence tag |
| US8232450B1 (en) | 2011-02-15 | 2012-07-31 | Yorktown Technologies, L.P. | Purple transgenic fluorescent ornamental fish |
| US8232451B1 (en) | 2011-02-15 | 2012-07-31 | Yorktown Technologies, L.P. | Blue transgenic fluorescent ornamental fish |
| US8975467B2 (en) | 2012-06-12 | 2015-03-10 | Yorktown Technologies, L.P. | Green transgenic fluorescent ornamental fish |
| US9392776B2 (en) | 2012-07-26 | 2016-07-19 | Yorktown Technologies, L.P. | Green transgenic fluorescent ornamental fish |
| US8987546B2 (en) | 2012-11-06 | 2015-03-24 | Yorktown Technologies, L.P. | Orange transgenic fluorescent ornamental fish |
| US9587230B2 (en) | 2013-09-05 | 2017-03-07 | Tempo Bioscience, Inc. | Human calcium binding domain biosensors |
| US9282729B2 (en) | 2014-01-31 | 2016-03-15 | Yorktown Technologies, L.P. | Purple transgenic fluorescent ornamental fish |
| US9380768B2 (en) | 2014-01-31 | 2016-07-05 | Yorktown Technologies, L.P. | Red transgenic fluorescent ornamental fish |
| US9363986B2 (en) | 2014-01-31 | 2016-06-14 | Yorktown Technologies, L.P. | Orange transgenic fluorescent ornamental fish |
| US9295238B2 (en) | 2014-01-31 | 2016-03-29 | Yorktown Technologies, L.P. | Pink transgenic fluorescent ornamental fish |
| WO2016011399A1 (en) * | 2014-07-17 | 2016-01-21 | Robinson John M | Artificial troponin complex |
| US9968077B2 (en) | 2014-11-07 | 2018-05-15 | Glofish Llc | Blue transgenic fluorescent ornamental fish |
| CN110892264A (zh) * | 2017-05-11 | 2020-03-17 | 格拉茨医科大学 | 基因编码的钾离子指示剂 |
| GB2604531B (en) | 2018-01-10 | 2023-01-25 | Glofish Llc | Transgenic rainbow shark |
| US12290055B2 (en) | 2018-11-13 | 2025-05-06 | GloFish, LLC | Transgenic betta |
| AU2020207368B2 (en) | 2019-01-10 | 2025-12-18 | GloFish, LLC | Transgenic barb |
| EP3882632A1 (de) * | 2020-03-18 | 2021-09-22 | Universite De Bordeaux | Neuartige ionenleitende kanalfusionuntereinheiten und verfahren zur verwendung davon |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002253261A (ja) * | 2001-03-05 | 2002-09-10 | Inst Of Physical & Chemical Res | 蛍光タンパク質 |
| JP3829252B2 (ja) * | 2001-06-08 | 2006-10-04 | 独立行政法人理化学研究所 | 蛍光蛋白質 |
-
2003
- 2003-08-04 AT AT03016691T patent/ATE389669T1/de not_active IP Right Cessation
- 2003-08-04 DE DE60319817T patent/DE60319817T2/de not_active Expired - Lifetime
- 2003-08-04 EP EP03016691A patent/EP1505073B1/de not_active Expired - Lifetime
-
2004
- 2004-08-04 US US10/567,091 patent/US20090035788A1/en not_active Abandoned
- 2004-08-04 WO PCT/EP2004/008739 patent/WO2005014636A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE60319817D1 (de) | 2008-04-30 |
| WO2005014636A1 (en) | 2005-02-17 |
| EP1505073B1 (de) | 2008-03-19 |
| EP1505073A1 (de) | 2005-02-09 |
| US20090035788A1 (en) | 2009-02-05 |
| DE60319817T2 (de) | 2009-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |