ATE390629T1 - Mikrophysiomessgerät - Google Patents

Mikrophysiomessgerät

Info

Publication number
ATE390629T1
ATE390629T1 AT01933483T AT01933483T ATE390629T1 AT E390629 T1 ATE390629 T1 AT E390629T1 AT 01933483 T AT01933483 T AT 01933483T AT 01933483 T AT01933483 T AT 01933483T AT E390629 T1 ATE390629 T1 AT E390629T1
Authority
AT
Austria
Prior art keywords
microphysiometer
microcalorimetric
devices
present
throughput
Prior art date
Application number
AT01933483T
Other languages
English (en)
Inventor
Katarina Verhaegen
Original Assignee
Ttp Labtech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ttp Labtech Ltd filed Critical Ttp Labtech Ltd
Application granted granted Critical
Publication of ATE390629T1 publication Critical patent/ATE390629T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K7/00—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements
    • G01K7/02—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using thermoelectric elements, e.g. thermocouples
    • G01K7/028—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using thermoelectric elements, e.g. thermocouples using microstructures, e.g. made of silicon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N25/00—Investigating or analyzing materials by the use of thermal means
    • G01N25/20—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
    • G01N25/48—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation
    • G01N25/4846—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation for a motionless, e.g. solid sample
    • G01N25/4866—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation for a motionless, e.g. solid sample by using a differential method

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Combustion & Propulsion (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Blast Furnaces (AREA)
AT01933483T 2000-05-08 2001-05-08 Mikrophysiomessgerät ATE390629T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20247500P 2000-05-08 2000-05-08

Publications (1)

Publication Number Publication Date
ATE390629T1 true ATE390629T1 (de) 2008-04-15

Family

ID=22750018

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01933482T ATE352036T1 (de) 2000-05-08 2001-05-08 Verfahren zur hochdurchsatzprofilierung neuer werkstoffe
AT01933483T ATE390629T1 (de) 2000-05-08 2001-05-08 Mikrophysiomessgerät

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01933482T ATE352036T1 (de) 2000-05-08 2001-05-08 Verfahren zur hochdurchsatzprofilierung neuer werkstoffe

Country Status (7)

Country Link
US (2) US20040038228A1 (de)
EP (2) EP1281067B1 (de)
JP (2) JP2003532877A (de)
AT (2) ATE352036T1 (de)
AU (2) AU5996201A (de)
DE (2) DE60133380T2 (de)
WO (2) WO2001085978A2 (de)

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DE10028692C2 (de) * 2000-06-09 2002-06-06 Micronas Gmbh Verfahren zur Untersuchung von membranumschlossenen Biokompartimenten
US20020132360A1 (en) 2000-11-17 2002-09-19 Flir Systems Boston, Inc. Apparatus and methods for infrared calorimetric measurements
US20040110301A1 (en) * 2000-11-17 2004-06-10 Neilson Andy C Apparatus and methods for measuring reaction byproducts
GB0117376D0 (en) * 2001-07-17 2001-09-05 Amersham Pharm Biotech Uk Ltd Thermocouple device
GR1004040B (el) * 2001-07-31 2002-10-31 Μεθοδος για την κατασκευη αιωρουμενων μεμβρανων πορωδους πυριτιου και εφαρμογης της σε αισθητηρες αεριων
US7473031B2 (en) * 2002-04-01 2009-01-06 Palo Alto Research Center, Incorporated Resistive thermal sensing
US7754492B2 (en) * 2002-04-01 2010-07-13 Palo Alto Research Center Incorporated Thermal sensing device
US7473030B2 (en) 2002-04-01 2009-01-06 Palo Alto Research Center Incorporated Thermal sensing
US7141210B2 (en) * 2002-04-01 2006-11-28 Palo Alto Research Center Incorporated Apparatus and method for a nanocalorimeter for detecting chemical reactions
US7147763B2 (en) * 2002-04-01 2006-12-12 Palo Alto Research Center Incorporated Apparatus and method for using electrostatic force to cause fluid movement
US7833800B2 (en) 2002-04-01 2010-11-16 Palo Alto Research Center Incorporated Thermal sensing with bridge circuitry
WO2004097373A2 (en) * 2003-04-28 2004-11-11 Univ Arizona Thermoelectric biosensor for analytes in a gas
US20080145840A1 (en) * 2003-06-30 2008-06-19 Astrazeneca Ab Isothermal Titration Calorimetry Assays
US7276351B2 (en) 2003-09-10 2007-10-02 Seahorse Bioscience Method and device for measuring multiple physiological properties of cells
US8658349B2 (en) 2006-07-13 2014-02-25 Seahorse Bioscience Cell analysis apparatus and method
US7419835B2 (en) * 2003-11-21 2008-09-02 Palo Alto Research Center Incorporated Screening for ligand binding at specific target sites
US7416897B2 (en) * 2003-11-21 2008-08-26 Palo Alto Research Center Incorporated Method for high-throughput screening assay sample preparation and analysis
JP4188287B2 (ja) 2004-07-15 2008-11-26 三井金属鉱業株式会社 熱式センサ及びそれを用いた測定装置
US20060040338A1 (en) * 2004-08-18 2006-02-23 Odyssey Thera, Inc. Pharmacological profiling of drugs with cell-based assays
US7914735B2 (en) * 2005-01-18 2011-03-29 Palo Alto Research Center Incorporated Use of physical barriers to minimize evaporative heat losses
TWI252920B (en) * 2005-03-25 2006-04-11 Ind Tech Res Inst Method of fabricating an integral device of a biochip integrated with micro thermo-electric elements and the apparatus thereof
US20080195349A1 (en) * 2005-04-21 2008-08-14 Vivactis N.V. Calorimetric Measuring Device
EP1785721A1 (de) * 2005-11-11 2007-05-16 Stratos Bio Ltd. Mikrobien-, Viren- und Säugerempfänglichkeit auf Wirkstoffe, die das Zellwachstum und den Zellstoffwechsel beeinflussen, und Wirkweise der Verbindungen
SE530138C2 (sv) 2006-05-30 2008-03-11 Symcel Ab Anordning och metod för mätning av värmeflöde från åtminstone ett prov samt kärlenhet för placering i nämnda anordning
US7632008B2 (en) * 2007-06-08 2009-12-15 Palo Alto Research Center Incorporated Ranking fragment types with calorimetry
DE102008042139A1 (de) * 2008-09-16 2010-03-18 Robert Bosch Gmbh Abgastaugliche Schutzschichten für Hochtemperatur ChemFET Abgassensoren
US8202702B2 (en) 2008-10-14 2012-06-19 Seahorse Bioscience Method and device for measuring extracellular acidification and oxygen consumption rate with higher precision
CN104471052B (zh) 2012-11-13 2017-06-13 海马生物科学公司 用于基于控制介质流动的三维组织测量的装置和方法
US9285330B2 (en) 2013-04-04 2016-03-15 Marquette University Calorimetric microfluidic sensor
CN116809131A (zh) 2014-06-02 2023-09-29 安捷伦科技有限公司 用于分析生物样本的单列微板系统和载体

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104804A (en) * 1990-06-04 1992-04-14 Molecular Devices Corporation Cell assay device used in a microphysiometer
EP0542422A1 (de) * 1991-11-12 1993-05-19 General Atomics Mikrotiterplatte mit mehreren Vertiefungen
US5255976A (en) * 1992-07-10 1993-10-26 Vertex Pharmaceuticals Incorporated Temperature gradient calorimeter
JP3488465B2 (ja) * 1993-10-28 2004-01-19 ヒューストン・アドバンスド・リサーチ・センター 結合反応を別々に検出する微細加工フロースルー多孔性装置
US5965452A (en) * 1996-07-09 1999-10-12 Nanogen, Inc. Multiplexed active biologic array
US5654150A (en) * 1995-06-07 1997-08-05 President And Fellows Of Harvard College Method of expression cloning
US6063637A (en) * 1995-12-13 2000-05-16 California Institute Of Technology Sensors for sugars and other metal binding analytes
DE69730699T2 (de) * 1996-11-01 2005-08-18 TA Instruments, Inc., New Castle Differentialabtastkalorimeter
WO1999053094A1 (fr) * 1997-03-10 1999-10-21 Hiroyoshi Hidaka Procede de detection in vivo d'un gene proteique cible a l'aide de medicament
US5739010A (en) * 1997-04-16 1998-04-14 Incyte Pharmaceuticals, Inc. Human transcription factor
EP0921391A1 (de) * 1997-12-05 1999-06-09 Interuniversitair Micro-Elektronica Centrum Vzw Vorrichtung und Verfahren zur thermischen Messung
ES2184434T3 (es) * 1998-03-27 2003-04-01 Aventis Pharma Gmbh Placa de microtitulacion miniaturizada para exploracion de alto rendimiento.
EA200001007A1 (ru) * 1998-03-31 2001-04-23 Дюпон Фармасьютикалз Компани Фармацевтические препараты для визуализации ангиогенных расстройств
US6402369B1 (en) * 1998-11-03 2002-06-11 Sarnoff Corporation Arrayable thermal assays
US6703008B2 (en) * 1999-03-05 2004-03-09 The Procter & Gamble Company Aerosol hair spray compositions comprising combinations of silicone-grafted copolymers
JP2004508552A (ja) * 2000-09-05 2004-03-18 ザ　アルゼクシス　カンパニー　インコーポレーティッド 熱量測定による標的選別試験法を利用した創薬

Also Published As

Publication number Publication date
EP1281068A2 (de) 2003-02-05
EP1281067A2 (de) 2003-02-05
WO2001085978A2 (en) 2001-11-15
AU5996201A (en) 2001-11-20
JP2003532876A (ja) 2003-11-05
AU2001259961A1 (en) 2001-11-20
WO2001085901A2 (en) 2001-11-15
EP1281068B1 (de) 2008-03-26
US20040038227A1 (en) 2004-02-26
US20040038228A1 (en) 2004-02-26
JP2003532877A (ja) 2003-11-05
EP1281067B1 (de) 2007-01-17
ATE352036T1 (de) 2007-02-15
WO2001085978A3 (en) 2002-06-27
DE60133380D1 (de) 2008-05-08
DE60133380T2 (de) 2009-04-02
WO2001085901A3 (en) 2002-06-06
DE60126077D1 (de) 2007-03-08

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Legal Events

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