ATE390937T1 - Methoden zur behandlung von hyperproliferativen krankheiten mit menschlichem mda-7 - Google Patents
Methoden zur behandlung von hyperproliferativen krankheiten mit menschlichem mda-7Info
- Publication number
- ATE390937T1 ATE390937T1 AT00950382T AT00950382T ATE390937T1 AT E390937 T1 ATE390937 T1 AT E390937T1 AT 00950382 T AT00950382 T AT 00950382T AT 00950382 T AT00950382 T AT 00950382T AT E390937 T1 ATE390937 T1 AT E390937T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- mda
- treating
- human
- hyperproliferative diseases
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 5
- 230000003463 hyperproliferative effect Effects 0.000 title abstract 5
- 102000003898 interleukin-24 Human genes 0.000 title abstract 3
- 108090000237 interleukin-24 Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000001415 gene therapy Methods 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 230000006882 induction of apoptosis Effects 0.000 abstract 1
- 230000017095 negative regulation of cell growth Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14435499P | 1999-07-15 | 1999-07-15 | |
| US20076800P | 2000-04-28 | 2000-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE390937T1 true ATE390937T1 (de) | 2008-04-15 |
Family
ID=26841928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00950382T ATE390937T1 (de) | 1999-07-15 | 2000-07-13 | Methoden zur behandlung von hyperproliferativen krankheiten mit menschlichem mda-7 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1307234B1 (de) |
| AT (1) | ATE390937T1 (de) |
| AU (1) | AU6349400A (de) |
| CA (1) | CA2379171A1 (de) |
| DE (1) | DE60038508T2 (de) |
| WO (1) | WO2001005437A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1650303B1 (de) | 1993-10-27 | 2008-05-28 | The Trustees of Columbia University of the City of New York | Methode zur Bildung einer subtrahierten cDNA Bank und ihre Verwendung |
| US5710137A (en) | 1996-08-16 | 1998-01-20 | The Trustees Of Columbia University In The City Of New York | Use of a melanoma differentiation associated gene (mda 7) for reversing a cancerous phenotype |
| EP1404359A2 (de) * | 2000-12-07 | 2004-04-07 | Board Of Regents, The University Of Texas System | Behandlungsverfahren mit menschlichem mda-7 |
| US20030082140A1 (en) | 2001-08-20 | 2003-05-01 | Fisher Paul B. | Combinatorial methods for inducing cancer cell death |
| EP1327688A1 (de) | 2002-01-14 | 2003-07-16 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Adenoviren mit erhöhter Lysisfähigkeit |
| JP2005533000A (ja) * | 2002-03-05 | 2005-11-04 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システム | Mda−7に関与する免疫誘導を増強する方法 |
| EP1578196A4 (de) * | 2002-12-23 | 2006-04-12 | Univ Columbia | Mda-7 und freie radikale bei der krebsbehandlung |
| US8034790B2 (en) | 2003-12-01 | 2011-10-11 | Introgen Therapeutics | Use of MDA-7 to inhibit pathogenic infectious organisms |
| EP2050458A1 (de) * | 2007-10-17 | 2009-04-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | IL24 zur Induzierung des Zelltodes hyperproliferativer oder autoimmuner Zellen |
| US12454561B2 (en) | 2018-03-19 | 2025-10-28 | Multivir Inc. | Methods and compositions comprising tumor suppressor gene therapy and CD122/CD132 agonists for the treatment of cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1650303B1 (de) * | 1993-10-27 | 2008-05-28 | The Trustees of Columbia University of the City of New York | Methode zur Bildung einer subtrahierten cDNA Bank und ihre Verwendung |
| BR9713632A (pt) * | 1996-12-23 | 2000-04-11 | Schering Corp | Citocina de mamìfero relacionada com a il-10 |
-
2000
- 2000-07-13 AU AU63494/00A patent/AU6349400A/en not_active Abandoned
- 2000-07-13 AT AT00950382T patent/ATE390937T1/de active
- 2000-07-13 EP EP00950382A patent/EP1307234B1/de not_active Expired - Lifetime
- 2000-07-13 CA CA002379171A patent/CA2379171A1/en not_active Abandoned
- 2000-07-13 DE DE60038508T patent/DE60038508T2/de not_active Expired - Lifetime
- 2000-07-13 WO PCT/US2000/019392 patent/WO2001005437A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE60038508D1 (de) | 2008-05-15 |
| WO2001005437A2 (en) | 2001-01-25 |
| DE60038508T2 (de) | 2009-04-30 |
| EP1307234B1 (de) | 2008-04-02 |
| CA2379171A1 (en) | 2001-01-25 |
| AU6349400A (en) | 2001-02-05 |
| WO2001005437A3 (en) | 2003-02-06 |
| EP1307234A2 (de) | 2003-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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