ATE391502T1 - Kristalline formen von fluvastatin-natrium - Google Patents

Kristalline formen von fluvastatin-natrium

Info

Publication number: ATE391502T1
Authority: AT; Austria
Prior art keywords: crystalline forms; fluvastatin sodium; fluvastatin; sodium; crystalline
Prior art date: 2001-08-03

Application number

AT02794517T

Other languages

English (en)

Inventor

Der Schaaf Paul Van

Claudia Marcolli

Martin Szelagiewicz

Andreas Burkhard

Heinz Wolleb

Annemarie Wolleb

Original Assignee

Ciba Sc Holding Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-03

Filing date

2002-07-25

Publication date

2008-04-15

2002-07-25 Application filed by Ciba Sc Holding Ag filed Critical Ciba Sc Holding Ag

2008-04-15 Application granted granted Critical

2008-04-15 Publication of ATE391502T1 publication Critical patent/ATE391502T1/de

Links

ZGGHKIMDNBDHJB-NRFPMOEYSA-M (3R,5S)-fluvastatin sodium Chemical compound [Na+].C12=CC=CC=C2N(C(C)C)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C1C1=CC=C(F)C=C1 ZGGHKIMDNBDHJB-NRFPMOEYSA-M 0.000 title 1
229960000868 fluvastatin sodium Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/04—Sodium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

AT02794517T 2001-08-03 2002-07-25 Kristalline formen von fluvastatin-natrium ATE391502T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01810756		2001-08-03

Publications (1)

Publication Number	Publication Date
ATE391502T1 true ATE391502T1 (de)	2008-04-15

Family

ID=8184071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02794517T ATE391502T1 (de)	2001-08-03	2002-07-25	Kristalline formen von fluvastatin-natrium

Country Status (16)

Country	Link
US (1)	US6696479B2 (de)
EP (1)	EP1429757B8 (de)
JP (2)	JP4681808B2 (de)
KR (1)	KR100975782B1 (de)
CN (2)	CN102516150A (de)
AR (1)	AR036205A1 (de)
AT (1)	ATE391502T1 (de)
AU (1)	AU2002333271B2 (de)
CA (1)	CA2454072A1 (de)
DE (1)	DE60226044T2 (de)
ES (1)	ES2304140T3 (de)
HU (1)	HUP0401141A3 (de)
IL (2)	IL159861A0 (de)
PL (1)	PL366905A1 (de)
RU (1)	RU2334738C2 (de)
WO (1)	WO2003013512A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7087631B2 (en) *	2002-07-18	2006-08-08	Inotek Pharmaceuticals Corporation	Aryltetrazole compounds, and compositions thereof
AU2003250086A1 (en) *	2002-07-26	2004-02-23	Ciba Specialty Chemicals Holging Inc.	Crystalline polymorphic and amorphous forms of benazepril hydrochloride
WO2004096765A2 (en) *	2003-05-01	2004-11-11	Morepen Laboratories Ltd.	A novel crystalline polymorph of fluvastatin sodium and a process for preparing it
JP2007524619A (ja) *	2003-06-18	2007-08-30	テバファーマシューティカルインダストリーズリミティド	フルバスタチンナトリウム結晶型、その調製方法、これを含有する組成物、およびその使用法
US7368468B2 (en) *	2003-06-18	2008-05-06	Teva Pharmaceutical Industries Ltd.	Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
US7368581B2 (en)	2003-06-18	2008-05-06	Teva Pharmaceutical Industries Ltd.	Process for the preparation of fluvastatin sodium crystal from XIV
US7892354B2 (en) *	2003-10-06	2011-02-22	Solvias Ag	Process for the parallel detection of crystalline forms of molecular solids
WO2005037787A1 (en) *	2003-10-16	2005-04-28	Ciba Specialty Chemicals Holding Inc.	Crystalline form of fluvastatin sodium
US20070179166A1 (en) *	2003-12-24	2007-08-02	Valerie Niddam-Hildesheim	Process for preparation of statins with high syn to anti ratio
US7851624B2 (en) *	2003-12-24	2010-12-14	Teva Pharamaceutical Industries Ltd.	Triol form of rosuvastatin and synthesis of rosuvastatin
WO2005080332A1 (en) *	2004-01-14	2005-09-01	Cadila Healthcare Limited	Novel form of fluvastatin sodium
US20070173536A1 (en) *	2004-02-06	2007-07-26	Ciba Specialty Chemicals Holding Inc.	Crystalline forms of zolmitriptan
US7241800B2 (en)	2004-03-17	2007-07-10	Mai De Ltd.	Anhydrous amorphous form of fluvastatin sodium
WO2006021967A1 (en) *	2004-08-26	2006-03-02	Biocon Limited	Process for the preparation of fluvastatin sodium form a.
WO2006030304A2 (en) *	2004-09-17	2006-03-23	Ranbaxy Laboratories Limited	Novel forms of fluvastatin sodium, processes for preparation and pharmaceutical compositions thereof
WO2006085338A2 (en) *	2005-02-11	2006-08-17	Jubilant Organosys Limited	Novel polymorphic forms of fluvastatin sodium and process for preparing the same
WO2006109147A1 (en) *	2005-04-12	2006-10-19	Glenmark Pharmaceuticals Limited	Substantially pure amorphous fluvastatin, processes for its preparation and pharmaceutical compositions containing same
WO2007039784A2 (en) *	2005-10-06	2007-04-12	Wockhardt Limited	A novel crystalline polymorph of fluvastatin sodium and process for preparing it
US20090082572A1 (en) *	2005-11-14	2009-03-26	Hetero Drugs Limited	Process for amorphous esomeprazole
DE07752084T1 (de) *	2006-02-27	2008-06-05	Teva Pharmaceutical Industries Ltd.	Neuartige formen von fluvastatin-natrium und herstellung davon
US20110015247A1 (en) *	2008-04-04	2011-01-20	Shodhana Laboratories Limited	Novel crystalline form of carvedilol dihydrogen phosphate and related processes
CN101684121B (zh) *	2008-09-22	2013-04-03	重庆医药工业研究院有限责任公司	培美曲塞二酸的新晶型及其制备方法
JP6115288B2 (ja) *	2012-04-27	2017-04-19	株式会社島津製作所	質量分析におけるピーク検出方法及びそのシステム
TW201806928A (zh) *	2016-07-01	2018-03-01	第一三共股份有限公司	胺基羧酸之酸加成鹽的結晶及其製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU570021B2 (en) *	1982-11-22	1988-03-03	Novartis Ag	Analogs of mevalolactone
JPS60500015A (ja) *	1982-11-22	1985-01-10	サンド・アクチエンゲゼルシヤフト	メバロラクトン同族体とその誘導体、これらの製造法およびこれらを含有する製薬学的組成物
US4739073A (en) *	1983-11-04	1988-04-19	Sandoz Pharmaceuticals Corp.	Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
HU217629B (hu) *	1991-12-12	2000-03-28	Novartis Ag.	Eljárás fluvasztatint tartalmazó stabilizált gyógyszerkészítmények előállítására
HRP960313B1 (en)	1995-07-17	2002-08-31	Warner Lambert Co	Form iii crystalline (r- (r, r)-2- (4-fluorophenyl) -beta-delta-hydroxy-5-(1-methylethyl) -3-phenyl-4- ((phenylamino) carbonyl -1h-pyrrole-1-heptanoic acid calcium salt (2:1)
PT907639E (pt) *	1996-06-24	2003-06-30	Novartis Ag	Compostos polimorficos
DE60112956T2 (de) *	2000-10-31	2006-06-14	Ciba Sc Holding Ag	Kristalline formen von fluvastatin sodium

2002
- 2002-07-25 IL IL15986102A patent/IL159861A0/xx active IP Right Grant
- 2002-07-25 PL PL02366905A patent/PL366905A1/xx not_active Application Discontinuation
- 2002-07-25 CN CN2011103995817A patent/CN102516150A/zh active Pending
- 2002-07-25 CN CN028151321A patent/CN1536999B/zh not_active Expired - Fee Related
- 2002-07-25 AU AU2002333271A patent/AU2002333271B2/en not_active Ceased
- 2002-07-25 JP JP2003518521A patent/JP4681808B2/ja not_active Expired - Fee Related
- 2002-07-25 EP EP02794517A patent/EP1429757B8/de not_active Expired - Lifetime
- 2002-07-25 AT AT02794517T patent/ATE391502T1/de not_active IP Right Cessation
- 2002-07-25 DE DE60226044T patent/DE60226044T2/de not_active Expired - Lifetime
- 2002-07-25 ES ES02794517T patent/ES2304140T3/es not_active Expired - Lifetime
- 2002-07-25 WO PCT/EP2002/008276 patent/WO2003013512A2/en not_active Ceased
- 2002-07-25 HU HU0401141A patent/HUP0401141A3/hu unknown
- 2002-07-25 KR KR1020047001615A patent/KR100975782B1/ko not_active Expired - Fee Related
- 2002-07-25 CA CA002454072A patent/CA2454072A1/en not_active Abandoned
- 2002-07-25 RU RU2004106528/04A patent/RU2334738C2/ru not_active IP Right Cessation
- 2002-07-30 US US10/208,687 patent/US6696479B2/en not_active Expired - Lifetime
- 2002-08-01 AR ARP020102927A patent/AR036205A1/es unknown
2004
- 2004-01-14 IL IL159861A patent/IL159861A/en not_active IP Right Cessation
2010
- 2010-07-23 JP JP2010165635A patent/JP2010265308A/ja active Pending

Also Published As

Publication number	Publication date
JP4681808B2 (ja)	2011-05-11
HUP0401141A3 (en)	2011-07-28
US20030032666A1 (en)	2003-02-13
JP2005501838A (ja)	2005-01-20
CA2454072A1 (en)	2003-02-20
CN1536999B (zh)	2012-08-08
EP1429757B1 (de)	2008-04-09
PL366905A1 (en)	2005-02-07
KR100975782B1 (ko)	2010-08-17
CN1536999A (zh)	2004-10-13
KR20040022226A (ko)	2004-03-11
US6696479B2 (en)	2004-02-24
EP1429757B8 (de)	2008-07-16
IL159861A0 (en)	2004-06-20
DE60226044T2 (de)	2009-05-14
AR036205A1 (es)	2004-08-18
HUP0401141A2 (hu)	2004-09-28
EP1429757A2 (de)	2004-06-23
JP2010265308A (ja)	2010-11-25
RU2334738C2 (ru)	2008-09-27
ES2304140T3 (es)	2008-09-16
CN102516150A (zh)	2012-06-27
RU2004106528A (ru)	2005-07-27
IL159861A (en)	2009-02-11
AU2002333271B2 (en)	2007-08-09
DE60226044D1 (de)	2008-05-21
WO2003013512A3 (en)	2003-11-20
WO2003013512A2 (en)	2003-02-20

Legal Events

Date	Code	Title	Description
2008-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE391502T1 (de)	2008-04-15	Kristalline formen von fluvastatin-natrium
NO20033733L (no)	2003-10-22	Festeinnretning for sternum
DE69905054D1 (de)	2003-02-27	KRISTALLINE FORMEN VON EtO2C-CH2-(R)Cgl-Aze-Pab-OH
EE200300447A (et)	2003-12-15	Asendatud bensofuraan-2-karboksamiidide derivaadid
ITMI20021038A0 (it)	2002-05-16	Disposizione di elettrodi
NO20041968L (no)	2004-05-11	Anvendelse av cystationin
DE60107074D1 (de)	2004-12-16	Kristallin form ii von cabergolin
ATE369339T1 (de)	2007-08-15	Pseudopolymorphe formen von carvedilol
EP1438664A4 (de)	2005-07-13	Subnetz-pooling
PT1322592E (pt)	2004-12-31	Derivados substituidos de 1-aminobutan-3-ol
DE60031450D1 (de)	2006-11-30	Polymorph v von torasemid
ATE382601T1 (de)	2008-01-15	Substituierte 4-aminocyclohexanolderivate
IS2431B (is)	2008-10-15	Nýjar indólafleiður
DE50207379D1 (de)	2006-08-10	Nachweis von entzündungen
FR2830515B1 (fr)	2004-01-30	Suspension de turboreacteur
IT251699Y1 (it)	2004-01-20	Struttura di lampada
FI5213U1 (fi)	2002-01-23	Valaisin
UA5977S (uk)	2002-05-15	Світильник
UA5532S (uk)	2001-12-17	Світильник
UA5978S (uk)	2002-05-15	Світильник
UA5976S (uk)	2002-05-15	Світильник
UA5975S (uk)	2002-05-15	Світильник
UA5974S (uk)	2002-05-15	Світильник
UA5533S (uk)	2001-12-17	Світильник
UA5979S (uk)	2002-05-15	Світильник