ATE392427T1 - Neue kristalline formen eines macrolidantibiotikums - Google Patents

Neue kristalline formen eines macrolidantibiotikums

Info

Publication number
ATE392427T1
ATE392427T1 AT00914336T AT00914336T ATE392427T1 AT E392427 T1 ATE392427 T1 AT E392427T1 AT 00914336 T AT00914336 T AT 00914336T AT 00914336 T AT00914336 T AT 00914336T AT E392427 T1 ATE392427 T1 AT E392427T1
Authority
AT
Austria
Prior art keywords
crystalline forms
new crystalline
macrolid
antibiotic
macrolid antibiotic
Prior art date
Application number
AT00914336T
Other languages
English (en)
Inventor
Robert Rafka
Douglas Allen
Colman RAGAN
Barry Morton
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE392427T1 publication Critical patent/ATE392427T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT00914336T 1999-05-18 2000-04-14 Neue kristalline formen eines macrolidantibiotikums ATE392427T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13464499P 1999-05-18 1999-05-18

Publications (1)

Publication Number Publication Date
ATE392427T1 true ATE392427T1 (de) 2008-05-15

Family

ID=22464300

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00914336T ATE392427T1 (de) 1999-05-18 2000-04-14 Neue kristalline formen eines macrolidantibiotikums

Country Status (43)

Country Link
US (1) US6583274B1 (de)
EP (1) EP1189912B1 (de)
JP (1) JP3897983B2 (de)
KR (1) KR100474229B1 (de)
CN (1) CN1203084C (de)
AP (1) AP2001002325A0 (de)
AR (1) AR020030A1 (de)
AT (1) ATE392427T1 (de)
AU (1) AU772283B2 (de)
BG (1) BG106150A (de)
BR (1) BR0011300A (de)
CA (1) CA2372206C (de)
CZ (1) CZ20014120A3 (de)
DE (1) DE60038610T2 (de)
DK (1) DK1189912T3 (de)
DZ (1) DZ3043A1 (de)
EA (1) EA003417B1 (de)
ES (1) ES2302689T3 (de)
GT (1) GT200000072A (de)
HK (1) HK1045521B (de)
HN (1) HN2000000056A (de)
HR (1) HRP20010849A2 (de)
HU (1) HUP0201341A3 (de)
IL (2) IL145946A0 (de)
IS (1) IS6127A (de)
MA (1) MA26735A1 (de)
MX (1) MXPA01011914A (de)
MY (1) MY133397A (de)
NO (1) NO320195B1 (de)
NZ (1) NZ514765A (de)
OA (1) OA11876A (de)
PA (1) PA8495001A1 (de)
PE (1) PE20010151A1 (de)
PL (1) PL353316A1 (de)
PT (1) PT1189912E (de)
SK (1) SK16472001A3 (de)
TN (1) TNSN00103A1 (de)
TW (1) TWI225066B (de)
UA (1) UA67842C2 (de)
UY (1) UY26144A1 (de)
WO (1) WO2000069874A1 (de)
YU (1) YU76601A (de)
ZA (1) ZA200109420B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
BRPI0017013B1 (pt) 2000-01-27 2015-07-14 Zoetis P Llc Composição de antibiótico azalídeo e método para sua obtenção
WO2002088158A1 (en) * 2001-04-27 2002-11-07 Pfizer Products Inc. Process for preparing 4'-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
AU2003271408B2 (en) * 2002-12-31 2008-07-17 Alembic Limited A process for the purification of roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
CN102378763A (zh) * 2009-01-30 2012-03-14 葛兰素集团有限公司 消炎的大环内酯
EP2402355A1 (de) * 2010-07-01 2012-01-04 Novartis AG Kristalline wasserfreie Formen II und III von Tulathromycin
WO2013013834A1 (en) 2011-07-27 2013-01-31 Farma Grs, D.O.O. New crystalline forms of tulathromycin
CN106008622A (zh) * 2016-08-02 2016-10-12 海门慧聚药业有限公司 泰拉霉素新晶型及其制备
CN109942652B (zh) * 2017-12-21 2022-04-26 洛阳惠中兽药有限公司 一种莱柯霉素晶型ⅰ及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO107257B1 (ro) * 1987-07-09 1993-10-30 Pfizer Procedeu de obtinere a unui dihidrat de azitromicina, cristalin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5844105A (en) * 1996-07-29 1998-12-01 Abbott Laboratories Preparation of crystal form II of clarithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
CZ20014120A3 (cs) 2003-01-15
DE60038610T2 (de) 2009-06-25
EP1189912B1 (de) 2008-04-16
DE60038610D1 (de) 2008-05-29
HN2000000056A (es) 2001-02-02
SK16472001A3 (sk) 2003-02-04
NZ514765A (en) 2004-05-28
AU772283B2 (en) 2004-04-22
PT1189912E (pt) 2008-05-16
NO20015598L (no) 2002-01-08
HRP20010849A2 (en) 2003-04-30
US6583274B1 (en) 2003-06-24
DK1189912T3 (da) 2008-06-30
KR20020007415A (ko) 2002-01-26
PL353316A1 (en) 2003-11-17
DZ3043A1 (fr) 2004-03-27
CN1203084C (zh) 2005-05-25
MXPA01011914A (es) 2002-05-06
CN1351607A (zh) 2002-05-29
TNSN00103A1 (fr) 2005-11-10
ZA200109420B (en) 2002-11-15
OA11876A (en) 2006-03-27
UA67842C2 (uk) 2004-07-15
IL145946A0 (en) 2002-07-25
CA2372206C (en) 2006-01-10
EA003417B1 (ru) 2003-04-24
HUP0201341A3 (en) 2003-03-28
MY133397A (en) 2007-11-30
NO20015598D0 (no) 2001-11-16
TWI225066B (en) 2004-12-11
KR100474229B1 (ko) 2005-03-08
PE20010151A1 (es) 2001-02-08
PA8495001A1 (es) 2002-02-21
AU3572900A (en) 2000-12-05
HK1045521A1 (en) 2002-11-29
AP2001002325A0 (en) 2001-12-31
BG106150A (bg) 2002-05-31
HUP0201341A2 (en) 2002-08-28
EP1189912A1 (de) 2002-03-27
EA200100984A1 (ru) 2002-06-27
ES2302689T3 (es) 2008-08-01
JP2002544283A (ja) 2002-12-24
AR020030A1 (es) 2002-03-27
GT200000072A (es) 2001-11-08
CA2372206A1 (en) 2000-11-23
MA26735A1 (fr) 2004-12-20
NO320195B1 (no) 2005-11-14
IL145946A (en) 2007-06-17
YU76601A (sh) 2004-09-03
IS6127A (is) 2001-10-26
BR0011300A (pt) 2002-02-26
JP3897983B2 (ja) 2007-03-28
UY26144A1 (es) 2000-12-29
WO2000069874A1 (en) 2000-11-23
HK1045521B (zh) 2005-12-09

Similar Documents

Publication Publication Date Title
ATE337334T1 (de) Phosphonatderivate eines glykopeptides
ATE271031T1 (de) Neue phenylpropargyletherderivate
MA27023A1 (fr) Formes cristallines d'azithromycine
DE60129334D1 (en) Polymorphe formen eines epothilon-analogons
EP1315045A4 (de) Lithographische lückenfüllerausbildungszusammensetzung
ATE211604T1 (de) Aufhängung eines reihenräumers
DE60043343D1 (de) Chromenderivate
BR0016395B1 (pt) Derivados de adamantano
FR2794101B1 (fr) Actionneur pneumatique
SI1147075T1 (sl) Postopek za pripravo L-fenilefrin hidroklorida
DE60028470D1 (de) Mehrzylinderrotationsverdichter
NO20023950L (no) Fremgangsmåte for fremstilling av en titanholdig zeolitt
DE60038610D1 (de) Neue kristalline formen eines macrolidantibiotikums
DE60031639D1 (de) Offsetdruckwerk
DE60111268D1 (de) Neue pleuromutilinderivate
ATE265422T1 (de) Neue phenylheteroalkylamin-derivate
DE60126125D1 (de) Neue carbapenem-derivate
NO20023973D0 (no) Fremgangsmåte for fremstilling av en titanholdig zeolitt
ID27701A (id) Proses untuk membuat senyawa-senyawa kroman yang diesterifikasi
DE60121607D1 (de) Gerät zur protokollübersetzung mit hilfe eines generischen zwischenprotokolls
DE59901954D1 (de) Fünfzylinderoffsetdruckeinheiten
DE69915044D1 (de) Verriegelbare Betätigungseinheit eines Ventils
DE60034982D1 (de) Magnetisches Druckverfahren
EE200300204A (et) Meetod distamütsiini derivaadi valmistamiseks
FR2774984B1 (fr) Purification du thiophene

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1189912

Country of ref document: EP

REN Ceased due to non-payment of the annual fee