ATE392616T1 - Assay mit dissoziativer fluoreszenzverstärkung - Google Patents

Assay mit dissoziativer fluoreszenzverstärkung

Info

Publication number
ATE392616T1
ATE392616T1 AT03708289T AT03708289T ATE392616T1 AT E392616 T1 ATE392616 T1 AT E392616T1 AT 03708289 T AT03708289 T AT 03708289T AT 03708289 T AT03708289 T AT 03708289T AT E392616 T1 ATE392616 T1 AT E392616T1
Authority
AT
Austria
Prior art keywords
sub
enhancement
dissociative
dissociative fluorescence
amplification assay
Prior art date
Application number
AT03708289T
Other languages
English (en)
Inventor
Ilkka Hemmilae
Kaj Blomberg
Veli-Matti Mukkala
Harri Hakala
Original Assignee
Wallac Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy filed Critical Wallac Oy
Application granted granted Critical
Publication of ATE392616T1 publication Critical patent/ATE392616T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331Preservative, buffer, anticoagulant or diluent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/15Inorganic acid or base [e.g., hcl, sulfuric acid, etc. ]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • Y10T436/200833Carbonyl, ether, aldehyde or ketone containing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Pyrane Compounds (AREA)
AT03708289T 2002-03-08 2003-02-28 Assay mit dissoziativer fluoreszenzverstärkung ATE392616T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/093,034 US7211440B2 (en) 2002-03-08 2002-03-08 Dissociative fluorescence enhancement assay

Publications (1)

Publication Number Publication Date
ATE392616T1 true ATE392616T1 (de) 2008-05-15

Family

ID=27804193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03708289T ATE392616T1 (de) 2002-03-08 2003-02-28 Assay mit dissoziativer fluoreszenzverstärkung

Country Status (10)

Country Link
US (2) US7211440B2 (de)
EP (1) EP1483582B1 (de)
JP (1) JP4339696B2 (de)
CN (1) CN100350250C (de)
AT (1) ATE392616T1 (de)
AU (1) AU2003212393A1 (de)
CA (1) CA2477385C (de)
DE (1) DE60320388T2 (de)
ES (1) ES2305446T3 (de)
WO (1) WO2003076939A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482444B2 (en) 2006-03-13 2009-01-27 Wallac Oy Terminating substrates for DNA polymerases
US8785352B2 (en) 2010-04-30 2014-07-22 Pharmaseq, Inc. Metal nanoparticle structures for enhancing fluorescence-based assays
US20130231468A1 (en) * 2010-11-22 2013-09-05 Takeshi Yamashita Rare earth metal complex
CN104641232A (zh) * 2012-04-24 2015-05-20 阿克森斯公司 用于表征和/或测定样品的方法
CN103674912B (zh) * 2013-12-03 2016-01-27 齐齐哈尔大学 吡啶季铵盐阳离子表面活性剂的荧光检测方法及其应用
CN103969432B (zh) * 2014-03-27 2016-02-17 中国科学院福建物质结构研究所 一种稀土纳米材料溶解增强时间分辨荧光免疫分析方法
CN117327105A (zh) * 2023-12-01 2024-01-02 浙江大学 一种稀土配合物荧光微球、制备方法及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE425439B (sv) * 1981-04-30 1982-09-27 Wallac Oy Immunologisk analys med lantanidkelatkomplex som markor
SE8301395L (sv) 1983-03-15 1984-09-16 Wallac Oy Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler
GB8622855D0 (en) * 1986-09-23 1986-10-29 Ekins R P Determining biological substance
SE8702824L (sv) 1987-07-10 1989-01-11 Wallac Oy Metall-kelaterande 2,6-disubstituerade pyridinfoereningar och deras anvaendning
SE8703682L (sv) 1987-09-24 1989-03-25 Wallac Oy Homogen bestaemningsmetod som utnyttjar affinitetsreaktioner
AU2714988A (en) 1987-10-23 1989-06-01 Siska Diagnostics, Inc. Lanthanide chelate-tagged nucleic acid probes
US6127529A (en) * 1988-06-29 2000-10-03 Wallac Oy Metal-chelating 2,6-disubstituted pyridine compounds and their use
FI88654C (fi) * 1991-03-15 1993-06-10 Datacity Center Oy Fluorescenshoejningsmetod
US6429026B1 (en) * 1996-04-08 2002-08-06 Innotrac Diagnostics Oy One-step all-in-one dry reagent immunoassay
FI963989A7 (fi) 1996-10-04 1998-04-05 Wallac Oy Homogeenisiä määritysmenetelmiä, jotka perustuvat luminesenssienergiasiirtoon
JP2000019171A (ja) * 1998-04-28 2000-01-21 Kazuko Matsumoto 標識プローブによる分析方法
US6030840A (en) * 1998-06-15 2000-02-29 Nen Life Sciences, Inc. Neutral enhancement of lanthanides for time resolved fluorescence
KR100669053B1 (ko) 1999-04-23 2007-01-15 알자 코포레이션 리포좀에 사용하기 위한 절단가능 결합을 갖는 콘쥬게이트
US6329205B1 (en) * 1999-08-31 2001-12-11 Molecular Probes, Inc. Detection method using luminescent europium-based protein stains
US20010023351A1 (en) 1999-12-01 2001-09-20 Eilers George J. Skin abrasion system and method
CN1108280C (zh) * 2000-09-18 2003-05-14 中国建筑材料科学研究院 混凝土高活性细钢渣粉掺合料及制备混凝土的方法
DE10127208A1 (de) 2001-06-05 2002-12-12 Basf Ag Polyurethanispersionen und deren Verwendung
DE60233742D1 (de) * 2001-10-10 2009-10-29 Hitachi High Tech Corp Leuchtverbindungen und markierungsreagentien für die diese verwendet werden

Also Published As

Publication number Publication date
US20070015284A1 (en) 2007-01-18
US7381567B2 (en) 2008-06-03
ES2305446T3 (es) 2008-11-01
EP1483582B1 (de) 2008-04-16
WO2003076939A1 (en) 2003-09-18
US20030170907A1 (en) 2003-09-11
EP1483582A1 (de) 2004-12-08
DE60320388D1 (de) 2008-05-29
AU2003212393A1 (en) 2003-09-22
CA2477385C (en) 2011-08-09
CN100350250C (zh) 2007-11-21
JP4339696B2 (ja) 2009-10-07
US7211440B2 (en) 2007-05-01
JP2005519305A (ja) 2005-06-30
CA2477385A1 (en) 2003-09-18
DE60320388T2 (de) 2009-05-28
CN1650165A (zh) 2005-08-03

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