ATE394477T1 - Squalene synthase (sqs) gen - Google Patents
Squalene synthase (sqs) genInfo
- Publication number
- ATE394477T1 ATE394477T1 AT03757888T AT03757888T ATE394477T1 AT E394477 T1 ATE394477 T1 AT E394477T1 AT 03757888 T AT03757888 T AT 03757888T AT 03757888 T AT03757888 T AT 03757888T AT E394477 T1 ATE394477 T1 AT E394477T1
- Authority
- AT
- Austria
- Prior art keywords
- astaxanthin
- gene
- animals
- carotenoids
- sqs
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108010022535 Farnesyl-Diphosphate Farnesyltransferase Proteins 0.000 title 2
- 102100037997 Squalene synthase Human genes 0.000 title 2
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 abstract 3
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 abstract 3
- 229940022405 astaxanthin Drugs 0.000 abstract 3
- 235000013793 astaxanthin Nutrition 0.000 abstract 3
- 239000001168 astaxanthin Substances 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 235000021466 carotenoid Nutrition 0.000 abstract 2
- 150000001747 carotenoids Chemical class 0.000 abstract 2
- 241000251468 Actinopterygii Species 0.000 abstract 1
- 241000972773 Aulopiformes Species 0.000 abstract 1
- 241000195493 Cryptophyta Species 0.000 abstract 1
- 230000003064 anti-oxidating effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000004040 coloring Methods 0.000 abstract 1
- 235000019688 fish Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000003642 reactive oxygen metabolite Substances 0.000 abstract 1
- 235000019515 salmon Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02021619 | 2002-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE394477T1 true ATE394477T1 (de) | 2008-05-15 |
Family
ID=32039103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03757888T ATE394477T1 (de) | 2002-09-27 | 2003-09-23 | Squalene synthase (sqs) gen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7351564B2 (de) |
| EP (1) | EP1543115B1 (de) |
| JP (1) | JP2006500054A (de) |
| KR (1) | KR101204225B1 (de) |
| CN (1) | CN100467593C (de) |
| AT (1) | ATE394477T1 (de) |
| AU (1) | AU2003273922A1 (de) |
| CA (1) | CA2498800C (de) |
| DE (1) | DE60320812D1 (de) |
| ES (1) | ES2305501T3 (de) |
| MX (1) | MXPA05002120A (de) |
| NO (1) | NO334836B1 (de) |
| WO (1) | WO2004029255A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2371967B1 (de) | 2005-03-18 | 2015-06-03 | DSM IP Assets B.V. | Produktion von Carotenoiden in Ölhaltigen Hefen und Pilzen |
| WO2006117536A1 (en) * | 2005-05-04 | 2006-11-09 | Tmo Renewables Limited | Thermophilic microorganisms with inactivated lactate dehydrogenase gene (ldh) for ethanol production |
| US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
| EP2326707B1 (de) * | 2008-08-12 | 2016-11-23 | Evolva, Inc. | Verfahren zur herstellung von isoprenoiden |
| EP2575432B1 (de) | 2010-06-02 | 2019-08-14 | Evolva, Inc. | Rekombinante herstellung von steviol-glycosiden |
| AU2012294452C1 (en) | 2011-08-08 | 2017-11-30 | Danstar Ferment Ag | Recombinant production of steviol glycosides |
| WO2014122227A2 (en) | 2013-02-06 | 2014-08-14 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| BR112015019160A2 (pt) | 2013-02-11 | 2017-08-22 | Dalgaard Mikkelsen Michael | Produção de glicosídeos de esteviol em hospedeiros recombinantes |
| CN114410493A (zh) | 2014-08-11 | 2022-04-29 | 埃沃尔瓦公司 | 在重组宿主中生产甜菊醇糖苷 |
| KR20170052647A (ko) | 2014-09-09 | 2017-05-12 | 에볼바 에스아 | 재조합 숙주에서 스테비올 글리코시드의 생성 |
| AU2016211124B2 (en) | 2015-01-30 | 2022-04-14 | Danstar Ferment Ag | Production of steviol glycosides in recombinant hosts |
| EP3271457B1 (de) | 2015-03-16 | 2021-01-20 | DSM IP Assets B.V. | Udp-glycosyltransferasen |
| EP3332018B1 (de) | 2015-08-07 | 2022-07-27 | Evolva SA | Erzeugung von steviolglycosiden in rekombinanten wirten |
| KR20180132696A (ko) | 2016-04-13 | 2018-12-12 | 에볼바 에스아 | 재조합 숙주에서의 스테비올 글리코사이드의 생산 |
| US10815514B2 (en) | 2016-05-16 | 2020-10-27 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| WO2018083338A1 (en) | 2016-11-07 | 2018-05-11 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| KR101922792B1 (ko) * | 2017-01-06 | 2018-11-27 | 전남대학교산학협력단 | 플라노코쿠스 유래 신규한 스쿠알렌 합성효소 및 이의 용도 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5182208A (en) | 1988-08-08 | 1993-01-26 | Igene Biotechnology, Inc. | Processes for in vivo production of astaxanthin and phaffia rhodozyma yeast of enhanced astaxanthin content |
| US5741898A (en) * | 1994-09-22 | 1998-04-21 | Hanley; Kathleen Marie | DNA sequence encoding nicotiana squalene synthetase |
| WO2000001650A1 (en) | 1998-07-06 | 2000-01-13 | Dcv, Inc. Doing Business As Bio-Technical Resources | Method of vitamin production |
| CA2487144C (en) * | 2002-06-21 | 2012-06-12 | Dsm Ip Assets B.V. | Increased carotenoid production by inhibition of squalene biosynthesis |
| ES2386359T3 (es) * | 2004-07-27 | 2012-08-17 | The Regents Of The University Of California | Células huésped modificadas genéticamente y uso de las mismas para producir compuestos isoprenoides |
-
2003
- 2003-09-23 AT AT03757888T patent/ATE394477T1/de not_active IP Right Cessation
- 2003-09-23 MX MXPA05002120A patent/MXPA05002120A/es active IP Right Grant
- 2003-09-23 WO PCT/EP2003/010573 patent/WO2004029255A2/en not_active Ceased
- 2003-09-23 CN CNB038226154A patent/CN100467593C/zh not_active Expired - Fee Related
- 2003-09-23 EP EP03757888A patent/EP1543115B1/de not_active Expired - Lifetime
- 2003-09-23 ES ES03757888T patent/ES2305501T3/es not_active Expired - Lifetime
- 2003-09-23 AU AU2003273922A patent/AU2003273922A1/en not_active Abandoned
- 2003-09-23 DE DE60320812T patent/DE60320812D1/de not_active Expired - Lifetime
- 2003-09-23 JP JP2004538991A patent/JP2006500054A/ja active Pending
- 2003-09-23 CA CA2498800A patent/CA2498800C/en not_active Expired - Fee Related
- 2003-09-23 KR KR1020057005351A patent/KR101204225B1/ko not_active Expired - Fee Related
- 2003-09-23 US US10/528,872 patent/US7351564B2/en not_active Expired - Fee Related
-
2005
- 2005-04-27 NO NO20052072A patent/NO334836B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003273922A1 (en) | 2004-04-19 |
| DE60320812D1 (en) | 2008-06-19 |
| US20060160172A1 (en) | 2006-07-20 |
| MXPA05002120A (es) | 2005-06-06 |
| CN1777681A (zh) | 2006-05-24 |
| ES2305501T3 (es) | 2008-11-01 |
| AU2003273922A8 (en) | 2004-04-19 |
| CA2498800C (en) | 2012-01-03 |
| CN100467593C (zh) | 2009-03-11 |
| KR101204225B1 (ko) | 2012-11-27 |
| JP2006500054A (ja) | 2006-01-05 |
| EP1543115A2 (de) | 2005-06-22 |
| CA2498800A1 (en) | 2004-04-08 |
| WO2004029255A2 (en) | 2004-04-08 |
| KR20050051673A (ko) | 2005-06-01 |
| NO20052072D0 (no) | 2005-04-27 |
| NO20052072L (no) | 2005-06-27 |
| NO334836B1 (no) | 2014-06-16 |
| US7351564B2 (en) | 2008-04-01 |
| EP1543115B1 (de) | 2008-05-07 |
| WO2004029255A3 (en) | 2004-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |