ATE394482T1 - Verfahren und zusammensetzungen für peptid-, protein- und peptidomimetische synthese - Google Patents

Verfahren und zusammensetzungen für peptid-, protein- und peptidomimetische synthese

Info

Publication number
ATE394482T1
ATE394482T1 AT02724888T AT02724888T ATE394482T1 AT E394482 T1 ATE394482 T1 AT E394482T1 AT 02724888 T AT02724888 T AT 02724888T AT 02724888 T AT02724888 T AT 02724888T AT E394482 T1 ATE394482 T1 AT E394482T1
Authority
AT
Austria
Prior art keywords
peptidomimmetic
peptide
protein
synthesis
compositions
Prior art date
Application number
AT02724888T
Other languages
English (en)
Inventor
Anthony C Forster
Stephen C Blacklow
Original Assignee
Anthony C Forster
Stephen C Blacklow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthony C Forster, Stephen C Blacklow filed Critical Anthony C Forster
Application granted granted Critical
Publication of ATE394482T1 publication Critical patent/ATE394482T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT02724888T 2001-01-25 2002-01-25 Verfahren und zusammensetzungen für peptid-, protein- und peptidomimetische synthese ATE394482T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26414701P 2001-01-25 2001-01-25

Publications (1)

Publication Number Publication Date
ATE394482T1 true ATE394482T1 (de) 2008-05-15

Family

ID=23004801

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02724888T ATE394482T1 (de) 2001-01-25 2002-01-25 Verfahren und zusammensetzungen für peptid-, protein- und peptidomimetische synthese

Country Status (7)

Country Link
US (1) US6977150B2 (de)
EP (1) EP1356036B1 (de)
JP (2) JP2004531225A (de)
AT (1) ATE394482T1 (de)
CA (1) CA2435812C (de)
DE (1) DE60226411D1 (de)
WO (1) WO2002059293A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4061043B2 (ja) 2000-12-28 2008-03-12 株式会社ポストゲノム研究所 ｉｎｖｉｔｒｏ転写／翻訳系によるペプチド等の製造方法
WO2003089454A2 (en) * 2002-04-19 2003-10-30 California Institute Of Technology Unnatural amino acid containing display libraries
WO2004110964A2 (en) * 2003-06-16 2004-12-23 Nuevolution A/S Encoded molecules by translation (emt)
BRPI0507169A (pt) 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
WO2007140471A2 (en) * 2006-05-31 2007-12-06 The Trustees Of Columbia University In The City Of New York Ribosome and rna display of biologically active small molecules
WO2007139573A1 (en) * 2006-05-31 2007-12-06 The Trustees Of Columbia University In The City Of New York Ribosome and rna display of biologically active small molecules
WO2008005529A2 (en) 2006-07-07 2008-01-10 The Trustees Columbia University In The City Of New York Cell-mediated directed evolution
US9182406B2 (en) * 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
JP5798489B2 (ja) * 2009-01-12 2015-10-21 ストロ バイオファーマ， インコーポレイテッド インビトロタンパク質合成システムを用いて非天然アミノ酸をタンパク質に選択的に導入するためのモノチャージシステム
US9422550B2 (en) 2011-08-01 2016-08-23 The General Hospital Corporation Protein and peptide libraries
PL2906592T3 (pl) 2012-10-12 2019-07-31 Sutro Biopharma, Inc. Proteolityczna inaktywacja wybranych białek w ekstraktach bakteryjnych dla ulepszonej ekspresji
US10011830B2 (en) 2013-05-19 2018-07-03 The Board of Trustee of theLeland Stanford junior University Devices and methods for display of encoded peptides, polypeptides, and proteins on DNA
WO2015084867A1 (en) * 2013-12-02 2015-06-11 Brandeis University Multivalent glycopeptides that tightly bind to target proteins
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
EP3274459A4 (de) * 2015-03-27 2018-08-22 The University of Queensland Plattform zur einlagerung von nichtnatürlicher aminosäure in proteine
US11174479B2 (en) 2018-08-13 2021-11-16 The Board Of Trustees Of The Leland Stanford Junior University Devices and methods for display of encoded peptides, PolyPeptides, and proteins on DNA
MX2022001664A (es) 2019-08-09 2022-07-19 Nutcracker Therapeutics Inc Aparato microfluídico y metodos de uso del mismo.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011922A1 (en) 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
US5643722A (en) * 1994-05-11 1997-07-01 Trustees Of Boston University Methods for the detection and isolation of proteins
JP4061043B2 (ja) * 2000-12-28 2008-03-12 株式会社ポストゲノム研究所 ｉｎｖｉｔｒｏ転写／翻訳系によるペプチド等の製造方法

Also Published As

Publication number Publication date
US6977150B2 (en) 2005-12-20
WO2002059293A2 (en) 2002-08-01
DE60226411D1 (de) 2008-06-19
CA2435812C (en) 2012-03-27
JP2004531225A (ja) 2004-10-14
EP1356036B1 (de) 2008-05-07
JP2010259440A (ja) 2010-11-18
AU2002255488A2 (en) 2002-08-06
JP4972191B2 (ja) 2012-07-11
CA2435812A1 (en) 2002-08-01
WO2002059293A3 (en) 2003-05-30
US20040091955A1 (en) 2004-05-13
EP1356036A2 (de) 2003-10-29

Similar Documents

Publication Publication Date Title
ATE394482T1 (de) Verfahren und zusammensetzungen für peptid-, protein- und peptidomimetische synthese
DE69732640D1 (de) Festphasen-peptidsynthese
BR0213207A (pt) remodelagem e glicoconjugação de peptìdeos
IL232501A (en) Peptide or polypeptide-resistant protein analogs and their uses
AR036196A1 (es) Agentes de contraste multimericos dirigidos a base de peptidos
WO2004099231A3 (en) Glycopegylation methods and proteins/peptides produced by the methods
WO2004113493A3 (en) Compositions and methods for enhanced expression of immunoglobulins from a single vector using a peptide cleavage site
BRPI9915679A8 (pt) Composições e métodos para aumentar a mineralização óssea
DZ3482A1 (fr) Secretagogues de l'hormone de croissance
SI2174946T1 (sl) Metode za kemično sintetiziranje himernih proteinov imunoglobulina
BR9509665A (pt) Composto composições e métodos
BG103091A (en) Shortened soluble receptors of type i & ii of the tumour necrotizing factor
EA200201138A1 (ru) Пептид, модулирующий рецептор тромбопоэтина
ATE170192T1 (de) Zusammensetzungen und methoden zur synthese des b-rezeptors für das natriuretische protein und verwendungsmethoden
BR0211761A (pt) depsipeptìdeos e processos para preparar os mesmos
YU394A (sh) Novi peptidi koji deluju kao antagonisti opijatskih receptora i postupci za njihovu izradu
ATE326981T1 (de) Isolierte peptide die aminosäuresequenzen von ny- eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen
SE9503679D0 (sv) Antioxidants
IL172729A0 (en) Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins
DE59809283D1 (de) Inhibitoren für den urokinaserezeptor
DE69333952D1 (de) Klonering von dem gen für das t gondii protein gp 28.5 peptidfragmente aus diesem protein und ihre verwendungen.
SE9604582D0 (sv) Novel compounds
DE69504795D1 (de) Methoden zur synthese und reinigung von peptiden
AR022150A1 (es) Acidos nucleicos derivados de monocitos y composiciones y metodos relacionados
DE69623635D1 (de) Mu-opioidligande: agonisten und antagonisten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties