ATE39574T1 - DEVICE FOR TREATMENT OF SAMPLES AT LOW TEMPERATURES. - Google Patents

DEVICE FOR TREATMENT OF SAMPLES AT LOW TEMPERATURES.

Info

Publication number
ATE39574T1
ATE39574T1 AT85304928T AT85304928T ATE39574T1 AT E39574 T1 ATE39574 T1 AT E39574T1 AT 85304928 T AT85304928 T AT 85304928T AT 85304928 T AT85304928 T AT 85304928T AT E39574 T1 ATE39574 T1 AT E39574T1
Authority
AT
Austria
Prior art keywords
specimen treatment
reservoir
specimen
treatment medium
treatment chamber
Prior art date
Application number
AT85304928T
Other languages
German (de)
Inventor
Hellmuth Sitte
Original Assignee
Reichert Optische Werke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reichert Optische Werke Ag filed Critical Reichert Optische Werke Ag
Application granted granted Critical
Publication of ATE39574T1 publication Critical patent/ATE39574T1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
    • F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
    • F17C2270/00—Applications
    • F17C2270/05—Applications for industrial use
    • F17C2270/0509—"Dewar" vessels

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Combustion & Propulsion (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Sludge (AREA)
  • Control Of Combustion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Apparatus for treating biological specimens at low temperatures for subsequent microscopic examination comprises a container having a specimen treatment chamber disposed in a vessel adapted to contain liquid coolant. The specimen treatment chamber is adapted to receive a specimen to be treated and a specimen treatment medium. Precooling means is provided for precooling the specimen treatment medium before it is introduced to the specimen treatment chamber. The precooling means comprises a reservoir communicating with the specimen treatment chamber, and delivery means for delivering the specimen treatment medium to the reservoir. The reservoir and delivery means are arranged so that specimen treatment medium flowing through the reservoir and delivery means is cooled by the liquid coolant, and so that the specimen treatment medium can flow through the delivery means in countercurrent heat exchange with specimen treatment medium flowing from the reservoir to the specimen treatment chamber.
AT85304928T 1984-07-12 1985-07-10 DEVICE FOR TREATMENT OF SAMPLES AT LOW TEMPERATURES. ATE39574T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843425744 DE3425744A1 (en) 1984-07-12 1984-07-12 DEVICE FOR DRAINAGE AND / OR POLYMERIZATION EMBEDDING BIOLOGICAL SAMPLES AT DEEP TEMPERATURES
EP85304928A EP0170450B1 (en) 1984-07-12 1985-07-10 Apparatus for treating specimens at low temperature

Publications (1)

Publication Number Publication Date
ATE39574T1 true ATE39574T1 (en) 1989-01-15

Family

ID=6240502

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85304928T ATE39574T1 (en) 1984-07-12 1985-07-10 DEVICE FOR TREATMENT OF SAMPLES AT LOW TEMPERATURES.

Country Status (7)

Country Link
US (1) US4723420A (en)
EP (1) EP0170450B1 (en)
JP (1) JPH0726895B2 (en)
AT (1) ATE39574T1 (en)
DE (1) DE3425744A1 (en)
ES (1) ES8604690A1 (en)
PT (1) PT80797B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62234910A (en) * 1986-04-07 1987-10-15 Meiki Co Ltd Apparatus for injection molding of disc
US4888956A (en) * 1987-01-16 1989-12-26 Roux Murray Pieter W Le Cryogenic apparatus and cryogenic methods
JPH0232151A (en) * 1988-07-21 1990-02-01 Diafoil Co Ltd Polyester composition
WO1990008171A1 (en) * 1989-01-10 1990-07-26 Teijin Limited Aromatic polyester film and production thereof
DE9104344U1 (en) * 1991-04-10 1991-08-08 Institut für Genetik und Kulturpflanzenforschung, O-4325 Gatersleben Cooling device for sample preparation for an electron microscope
AT403097B (en) * 1992-09-08 1997-11-25 Sitte Hellmuth DEVICE FOR DRAINING AND / OR EMBEDDING SAMPLES
AT403096B (en) * 1992-09-08 1997-11-25 Sitte Hellmuth METHOD AND DEVICE FOR PREPARING MICROSCOPIC, IN PARTICULAR ELECTRON MICROSCOPIC PREPARATIONS FOR THE CUT PREPARATION
JP2521397B2 (en) * 1992-09-30 1996-08-07 東洋紡績株式会社 Polyester composition
US5309722A (en) * 1992-11-06 1994-05-10 Harsco Corporation Temperature control system for liquid nitrogen refrigerator
US5893269A (en) * 1997-06-12 1999-04-13 Yale University Crystal freezing apparatus
JP2005098702A (en) * 1999-10-07 2005-04-14 Seitai Kagaku Kenkyusho:Kk Biological tissue sample preparation method and apparatus
US6871700B2 (en) * 2000-11-17 2005-03-29 G & H Technologies Llc Thermal flux regulator
DE10146371A1 (en) * 2001-09-20 2003-04-17 Georg S Wengler Mobile unit, for harvesting human or animal stem cells, comprises a container divided into sections for the extraction, preservation and storage of stem cells from donor materials
US7015568B2 (en) * 2003-08-21 2006-03-21 Texas Instruments Incorporated System for ultraviolet atmospheric seed layer remediation
DE102004041965B4 (en) * 2004-08-31 2009-08-13 Leica Mikrosysteme Gmbh Device and method for freeze substitution and embedding of biological samples
DE102004055148B4 (en) * 2004-11-16 2006-11-09 Leica Mikrosysteme Gmbh Device for freezing or cryogenic substitution
DE102005003284B4 (en) * 2005-01-25 2022-05-05 Leica Mikrosysteme Gmbh Dewar for automated freezing or cryogenic substitution
DE102005003286B4 (en) * 2005-01-25 2009-07-02 Leica Mikrosysteme Gmbh Container for a device for automated freezing or cryogenic substitution
EP2008037A2 (en) * 2006-03-30 2008-12-31 Cornell Research Foundation, Inc. System and method for increased cooling rates in rapid cooling of small biological samples
BRPI0712600B1 (en) * 2006-05-19 2015-10-27 Mary Kay Inc topical composition for skin care and method for skin exfoliation.
JP5584153B2 (en) * 2011-02-28 2014-09-03 大陽日酸株式会社 Preliminary freezer
EP2967045B1 (en) 2013-03-12 2019-06-26 Mary Kay, Inc. Preservative system
CN106104250B (en) 2014-04-03 2019-12-13 株式会社日立高新技术 low temperature storage system
JP6679590B2 (en) * 2014-11-13 2020-04-15 ライカ ミクロジュステーメ ゲーエムベーハー Freezing machine with container used for frozen samples
US20190104594A1 (en) * 2017-10-02 2019-04-04 Worthington Industries, Inc. Light device for dewar
FR3068769B1 (en) * 2018-03-13 2021-01-01 Air Liquide "DEVICE AND METHOD FOR COOLING AT CRYOGENIC TEMPERATURE"
US12151245B2 (en) * 2020-11-20 2024-11-26 Fred Hutchinson Cancer Research Center Bio-specimen refrigeration system
US11808679B2 (en) * 2022-01-27 2023-11-07 Expresslo Llc Method and apparatus for cryogenic and environmental controlled specimen handling
WO2026047085A1 (en) * 2024-08-29 2026-03-05 Struers ApS An apparatus for and a method of sample mounting

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2214009A (en) * 1937-08-26 1940-09-10 Jr Carl F Boester Cooling apparatus for cooling beverages and the like
US3027734A (en) * 1960-03-18 1962-04-03 Reflectotherm Inc Chilling and freezing systems
US4232453A (en) * 1978-09-25 1980-11-11 C. Reichert Optische Werke, Ag Device for freeze drying and synthetic resin impregnation when necessary of small biological objects for electron microscopic examination
DE2944464A1 (en) * 1979-11-03 1981-05-14 C. Reichert Optische Werke Ag, Wien DEVICE FOR THE CRYSTAL SUBSTITUTION OF SMALL BIOLOGICAL OBJECTS FOR MICROSCOPIC, IN PARTICULAR ELECTRON MICROSCOPIC EXAMINATIONS
NL7908379A (en) * 1979-11-16 1981-06-16 Heesen T J DEVICE FOR TREATING GRANULAR MATERIAL BY USING AIR OR GAS.
DE3042578A1 (en) * 1980-11-12 1982-06-24 C. Reichert Optische Werke Ag, Wien INCUBATIONAL DEVICE FOR THE FIXATION, DRAINAGE AND EMBEDDING OF BIOLOGICAL OBJECTS FOR MICROSCOPIC, IN PARTICULAR ELECTRON MICROSCOPIC EXAMINATIONS
US4429542A (en) * 1981-08-10 1984-02-07 Hoxan Corporation Method of freezing fertilized ova, spermatozoa or the like and apparatus therefor
DE3332586C2 (en) * 1983-09-09 1986-03-20 C. Reichert Optische Werke Ag, Wien Device for avoiding splashing of liquid cooling media when quickly introducing biological-medical objects into a cooling bath as part of an immersion cryofixation
DE3234457C2 (en) * 1982-09-17 1984-09-20 C. Reichert Optische Werke Ag, Wien Cooling bath for rapid cooling of samples, especially for the cryofixation of biological objects for a subsequent light or electron optical examination
US4471629A (en) * 1983-05-31 1984-09-18 Mount Carmel Research And Education Corporation Method of freezing and transplant of kidneys and apparatus
US4530816A (en) * 1983-06-15 1985-07-23 Hamilton Farm Method and device for cooling, preserving and safely transporting biological material

Also Published As

Publication number Publication date
JPH0726895B2 (en) 1995-03-29
DE3425744A1 (en) 1986-01-16
DE3425744C2 (en) 1988-10-27
US4723420A (en) 1988-02-09
EP0170450A1 (en) 1986-02-05
PT80797A (en) 1985-08-01
ES8604690A1 (en) 1986-02-01
ES545105A0 (en) 1986-02-01
EP0170450B1 (en) 1988-12-28
JPS6140538A (en) 1986-02-26
PT80797B (en) 1986-11-20

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Legal Events

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