ATE395932T1 - Rekombinanter immunschwächepoxvirus - Google Patents
Rekombinanter immunschwächepoxvirusInfo
- Publication number
- ATE395932T1 ATE395932T1 AT95916151T AT95916151T ATE395932T1 AT E395932 T1 ATE395932 T1 AT E395932T1 AT 95916151 T AT95916151 T AT 95916151T AT 95916151 T AT95916151 T AT 95916151T AT E395932 T1 ATE395932 T1 AT E395932T1
- Authority
- AT
- Austria
- Prior art keywords
- ctl
- iiib
- viruses
- recombinant viruses
- bru
- Prior art date
Links
- 230000007812 deficiency Effects 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 9
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101100462138 Brassica napus OlnB1 gene Proteins 0.000 abstract 1
- 102100031699 Choline transporter-like protein 1 Human genes 0.000 abstract 1
- 102100035954 Choline transporter-like protein 2 Human genes 0.000 abstract 1
- 101100224481 Dictyostelium discoideum pole gene Proteins 0.000 abstract 1
- 101000940912 Homo sapiens Choline transporter-like protein 1 Proteins 0.000 abstract 1
- 101000948115 Homo sapiens Choline transporter-like protein 2 Proteins 0.000 abstract 1
- 206010061598 Immunodeficiency Diseases 0.000 abstract 1
- 208000029462 Immunodeficiency disease Diseases 0.000 abstract 1
- 101150110488 POL2 gene Proteins 0.000 abstract 1
- 101100117436 Thermus aquaticus polA gene Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 229940023860 canarypox virus HIV vaccine Drugs 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000007813 immunodeficiency Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C07K2319/00—Fusion polypeptide
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- C12N2730/00—Reverse transcribing DNA viruses
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24141—Use of virus, viral particle or viral elements as a vector
- C12N2770/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Health & Medical Sciences (AREA)
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- General Engineering & Computer Science (AREA)
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- Wood Science & Technology (AREA)
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- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
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- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22384294A | 1994-04-06 | 1994-04-06 | |
| US08/417,210 US5863542A (en) | 1991-03-07 | 1995-04-05 | Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE395932T1 true ATE395932T1 (de) | 2008-06-15 |
Family
ID=26918187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95916151T ATE395932T1 (de) | 1994-04-06 | 1995-04-06 | Rekombinanter immunschwächepoxvirus |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US5863542A (de) |
| EP (1) | EP0752887B1 (de) |
| JP (4) | JP4007456B2 (de) |
| AT (1) | ATE395932T1 (de) |
| CA (1) | CA2187031A1 (de) |
| DE (1) | DE69535757D1 (de) |
| WO (1) | WO1995027507A1 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5505941A (en) * | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US7767449B1 (en) | 1981-12-24 | 2010-08-03 | Health Research Incorporated | Methods using modified vaccinia virus |
| US7374768B1 (en) | 1990-09-25 | 2008-05-20 | Xenova Research Limited | Viral vaccines |
| US5863542A (en) * | 1991-03-07 | 1999-01-26 | Virogenetics Corporation | Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts |
| ATE181108T1 (de) | 1991-08-26 | 1999-06-15 | Immuno Ag | Direkt molekuläre klonierung eines modifizierten genoms eines chordopocken-virus |
| ES2243937T3 (es) * | 1994-04-29 | 2005-12-01 | Baxter Healthcare S.A. | Poxvirus recombinados en regiones esenciales con la ayuda de polinucleotidos extraños. |
| EP2298900A1 (de) * | 1996-09-17 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Zusammensetzungen und Verfahren zur Behandlung intrazellulärer Erkrankungen |
| US7255862B1 (en) * | 1996-11-14 | 2007-08-14 | Connaught Technology Corporation | ALVAC/FIV constructs |
| US5990091A (en) * | 1997-03-12 | 1999-11-23 | Virogenetics Corporation | Vectors having enhanced expression, and methods of making and uses thereof |
| EP1087789A2 (de) * | 1998-06-26 | 2001-04-04 | Aventis Pasteur | Verwendung von pockenviren als mittel zur erhöhung der spezifischen immunität |
| US20040002472A1 (en) * | 2000-01-21 | 2004-01-01 | Audonnet Jean-Christophe Francis | Vaccination or immunization using a prime-boost regimen |
| JP2003529559A (ja) * | 2000-01-31 | 2003-10-07 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規用途 |
| US20040105871A1 (en) * | 2000-03-02 | 2004-06-03 | Robinson Harriet L. | Compositions and methods for generating an immune response |
| US8623379B2 (en) * | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| US20020106798A1 (en) | 2000-03-02 | 2002-08-08 | Robinson Harriet L. | DNA expression vectors and methods of use |
| EP1278541A1 (de) * | 2000-04-28 | 2003-01-29 | The Government of The United States of America, as represented by The Department of Health and Human Services | Verbesserung der immunogenität bei der verwendung einer kombination von dns und vacciniavirus-vektor impfstoffen |
| US6582920B2 (en) * | 2000-09-01 | 2003-06-24 | Gen-Probe Incorporated | Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations |
| WO2002027321A2 (en) | 2000-09-26 | 2002-04-04 | Health Research Incorporated | Analysis of hiv-1 coreceptor use in the clinical care of hiv-1-infected patients |
| CN100446812C (zh) * | 2001-03-08 | 2008-12-31 | 美国国有健康与人类服务部 | 表达修饰的hiv包膜、gag和pol基因的mva |
| EP1281767A3 (de) * | 2001-07-31 | 2003-05-28 | Aladar A. Szalay | Lichtausstrahlende Mikroorganismen und Zellen für die Diagnose und Therapie von Tumoren |
| ES2344253T3 (es) | 2001-10-11 | 2010-08-23 | MERCK SHARP & DOHME CORP. | Vacuna contra el virus de la hepatitis c. |
| AU2003301841A1 (en) * | 2002-05-01 | 2004-06-07 | National Institutes Of Health | Immunotherapy regimens in hiv-infected patients |
| US7501127B2 (en) | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| US20030228261A1 (en) * | 2002-06-05 | 2003-12-11 | Aladar Szalay | Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue |
| EP1369491A1 (de) * | 2002-06-05 | 2003-12-10 | Aladar A. Szalay | Lichtemittierende Mikroorganismen und Zellen für die Diagnose und Therapie von Krankheiten assoziiert mit Wunden oder entzündetem Gewebe |
| US7135556B2 (en) * | 2002-07-19 | 2006-11-14 | Schering Corporation | NPC1L1 (NPC3) and methods of use thereof |
| MXPA05013879A (es) | 2003-06-18 | 2006-06-27 | Genelux Corp | Virus de la vaccinia recombinantes modificados y otros microorganismos, y usos de los mismos. |
| US20100189747A1 (en) * | 2003-07-31 | 2010-07-29 | Raymond Weinstein | Compositions and methods for treating or preventing hiv infection |
| CA2610919C (en) | 2005-06-17 | 2013-09-10 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Hepatitis c virus nucleic acid vaccine |
| US8202523B2 (en) * | 2005-09-22 | 2012-06-19 | ProSci, Inc. | Glycosylated polypeptides produced in yeast mutants and methods of use thereof |
| CA2637600A1 (en) | 2006-01-17 | 2007-07-26 | Health Research, Inc. | Heteroduplex tracking assay |
| JP2009535027A (ja) * | 2006-04-27 | 2009-10-01 | シンガポール ヘルス サービシーズ ピーティーイー リミテッド | 抗菌ペプチド |
| EP2023954B1 (de) * | 2006-05-19 | 2013-07-17 | Sanofi Pasteur, Inc. | Immunologische zusammensetzung |
| TW200819540A (en) | 2006-07-11 | 2008-05-01 | Genelux Corp | Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders |
| US20100068217A1 (en) * | 2006-08-25 | 2010-03-18 | Kwong Peter D | Epitope-transplant scaffolds and their use |
| EP2415783B1 (de) | 2006-10-16 | 2016-12-14 | Genelux Corporation | Modifizierte Impfstoffvirusstämme zur Verwendung in einem Diagnose- und Therapieverfahren |
| US20090081639A1 (en) * | 2007-05-31 | 2009-03-26 | Phil Hill | Assay for sensitivity to chemotherapeutic agents |
| DK2212345T3 (en) * | 2007-11-19 | 2016-03-21 | Transgene Sa | Oncolytic poxvirus vectors |
| EP2236520A1 (de) * | 2009-03-31 | 2010-10-06 | Leukocare Ag | Stabilisierungszusammensetzung für immobilisierte Biomoleküle |
| US8871220B2 (en) | 2009-04-03 | 2014-10-28 | Merial Limited | Newcastle disease virus vectored avian vaccines |
| CA2760315C (en) | 2009-04-30 | 2019-05-28 | Centre Hospitalier Universitaire Vaudois Lausanne (Chuv) | Modified immunization vectors |
| EP3213766A1 (de) | 2009-12-28 | 2017-09-06 | Merial Ltd. | Rekombinantes ndv-antigen und verwendungen davon |
| WO2011106705A2 (en) | 2010-02-26 | 2011-09-01 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Dna-protein vaccination protocols |
| US8986706B2 (en) | 2010-08-31 | 2015-03-24 | Merial, Inc. | Newcastle disease virus vectored herpesvirus vaccines |
| DK3205353T3 (da) | 2011-03-21 | 2021-04-06 | Altimmune Inc | Hurtig- og langtidsvirkende immunologisk terapeutisk middel |
| WO2013083254A1 (en) | 2011-12-09 | 2013-06-13 | Bavarian Nordic A/S | Poxvirus vector for the expression of bacterial antigens linked to tetanus toxin fragment c |
| ES2959642T3 (es) | 2015-05-13 | 2024-02-27 | The Us Secretary Of The Department Of Health And Human Services | Metodos y composiciones para inducir una respuesta inmunitaria mediante construcciones con elementos conservados |
| WO2016196366A1 (en) | 2015-05-29 | 2016-12-08 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Extension of replicative lifespan in diseases of premature aging using p53 isoforms |
| PH12017502380B1 (en) | 2015-06-23 | 2022-10-26 | Merial Inc | Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof |
| CA3124773A1 (en) * | 2018-12-28 | 2020-07-02 | Transgene | M2-defective poxvirus |
| WO2020230785A1 (ja) | 2019-05-14 | 2020-11-19 | 国立大学法人鳥取大学 | 細胞融合を誘導するワクシニアウイルス及びその利用 |
| US20230355691A1 (en) | 2020-11-17 | 2023-11-09 | National University Corporation Tottori University | Novel recombinant vaccinia virus and use thereof |
| EP4551240A1 (de) | 2022-07-08 | 2025-05-14 | Viromissile, Inc. | Onkolytische vacciniaviren und rekombinante viren sowie verfahren zur verwendung davon |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10399032I1 (de) * | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
| GB8923123D0 (en) * | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| EP0575491B1 (de) * | 1991-03-07 | 2003-08-13 | Virogenetics Corporation | Gentechnologisch hergestellter stamm für impfstoffe |
| US5863542A (en) * | 1991-03-07 | 1999-01-26 | Virogenetics Corporation | Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts |
| DE69233080T2 (de) * | 1991-06-14 | 2004-04-15 | Connaught Technology Corp., Greenville | Rekombinanter hiv-spezifischer impfstoff aus poxviru |
| AU693098B2 (en) * | 1993-06-09 | 1998-06-25 | Connaught Laboratories Limited | Tandem synthetic HIV-1 peptides |
-
1995
- 1995-04-05 US US08/417,210 patent/US5863542A/en not_active Expired - Lifetime
- 1995-04-06 EP EP95916151A patent/EP0752887B1/de not_active Expired - Lifetime
- 1995-04-06 CA CA002187031A patent/CA2187031A1/en not_active Abandoned
- 1995-04-06 AT AT95916151T patent/ATE395932T1/de not_active IP Right Cessation
- 1995-04-06 WO PCT/US1995/003989 patent/WO1995027507A1/en not_active Ceased
- 1995-04-06 JP JP52637895A patent/JP4007456B2/ja not_active Expired - Fee Related
- 1995-04-06 DE DE69535757T patent/DE69535757D1/de not_active Expired - Fee Related
-
1998
- 1998-08-14 US US09/136,159 patent/US6596279B1/en not_active Expired - Lifetime
-
2003
- 2003-05-20 US US10/441,788 patent/US20030223987A1/en not_active Abandoned
-
2006
- 2006-02-09 JP JP2006032543A patent/JP4098811B2/ja not_active Expired - Fee Related
-
2007
- 2007-06-20 JP JP2007162393A patent/JP4138848B2/ja not_active Expired - Fee Related
- 2007-07-18 JP JP2007186820A patent/JP2008000138A/ja active Pending
- 2007-08-08 US US11/891,027 patent/US20080188640A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4098811B2 (ja) | 2008-06-11 |
| EP0752887B1 (de) | 2008-05-21 |
| JP2006141407A (ja) | 2006-06-08 |
| US5863542A (en) | 1999-01-26 |
| US20030223987A1 (en) | 2003-12-04 |
| CA2187031A1 (en) | 1995-10-19 |
| JP2007297396A (ja) | 2007-11-15 |
| JP2008000138A (ja) | 2008-01-10 |
| JPH09511649A (ja) | 1997-11-25 |
| US20080188640A1 (en) | 2008-08-07 |
| EP0752887A4 (de) | 1997-08-20 |
| DE69535757D1 (de) | 2008-07-03 |
| US6596279B1 (en) | 2003-07-22 |
| WO1995027507A1 (en) | 1995-10-19 |
| JP4007456B2 (ja) | 2007-11-14 |
| EP0752887A1 (de) | 1997-01-15 |
| JP4138848B2 (ja) | 2008-08-27 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |