ATE397063T1 - Fibroblasten-wachstumsfaktor-19 - Google Patents

Fibroblasten-wachstumsfaktor-19

Info

Publication number
ATE397063T1
ATE397063T1 AT98961795T AT98961795T ATE397063T1 AT E397063 T1 ATE397063 T1 AT E397063T1 AT 98961795 T AT98961795 T AT 98961795T AT 98961795 T AT98961795 T AT 98961795T AT E397063 T1 ATE397063 T1 AT E397063T1
Authority
AT
Austria
Prior art keywords
polypeptides
present
methods
treatment
diagnosis
Prior art date
Application number
AT98961795T
Other languages
English (en)
Inventor
David Botstein
Audrey Goddard
Austin Gurney
Kenneth Hillan
David Lawrence
Margaret Roy
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE397063T1 publication Critical patent/ATE397063T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98961795T 1997-11-25 1998-11-25 Fibroblasten-wachstumsfaktor-19 ATE397063T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6684097P 1997-11-25 1997-11-25
US15834298A 1998-09-21 1998-09-21

Publications (1)

Publication Number Publication Date
ATE397063T1 true ATE397063T1 (de) 2008-06-15

Family

ID=26747212

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98961795T ATE397063T1 (de) 1997-11-25 1998-11-25 Fibroblasten-wachstumsfaktor-19

Country Status (11)

Country Link
EP (1) EP1032668B1 (de)
JP (1) JP3653469B2 (de)
KR (2) KR100506786B1 (de)
AT (1) ATE397063T1 (de)
AU (1) AU733222B2 (de)
CA (1) CA2309783C (de)
DE (1) DE69839571D1 (de)
DK (1) DK1032668T3 (de)
IL (2) IL136055A0 (de)
NZ (1) NZ504425A (de)
WO (1) WO1999027100A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605441B1 (en) 1995-06-05 2003-08-12 Human Genome Sciences, Inc. Antibodies against fibroblast growth factor 11
US6787640B2 (en) 1995-06-05 2004-09-07 Human Genome Sciences, Inc. Fibroblast growth factor 14
US20050043234A1 (en) 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
KR100506786B1 (ko) * 1997-11-25 2005-08-08 제넨테크, 인크. 섬유아세포 성장인자-19
AU3900000A (en) * 1999-03-19 2000-10-09 Chiron Corporation Human fgf gene and gene expression products
JP2003501087A (ja) * 1999-06-09 2003-01-14 ジェネンテック・インコーポレーテッド 腫瘍の治療のための組成物と方法
US7459540B1 (en) * 1999-09-07 2008-12-02 Amgen Inc. Fibroblast growth factor-like polypeptides
PT1214409E (pt) * 1999-09-08 2006-10-31 Genentech Inc Acidos nucleicos e polipeptidos do factor de crescimento de fibroblastos-19 (fgf-19) e metodos de utilizacao para o tratamento de obesidade
EP1214409B1 (de) * 1999-09-08 2006-05-17 Genentech, Inc. Fibroblasten-wachstumsfaktor-19 (fgf-19) nukleinsäure und polypeptide und verfahren zu deren verwendung für behandlung von fettleibigkeit
JP2003516731A (ja) * 1999-11-18 2003-05-20 カイロン コーポレイション ヒトｆｇｆ−２１遺伝子および遺伝子発現産物
US6716626B1 (en) 1999-11-18 2004-04-06 Chiron Corporation Human FGF-21 nucleic acids
AU2759201A (en) * 2000-01-05 2001-07-16 Zymogenetics Inc. Novel fgf homolog zfgf12
AU2631001A (en) * 2000-01-05 2001-07-16 Zymogenetics Inc. Novel fgf homolog zfgf11
EP1947182A1 (de) * 2000-02-15 2008-07-23 Amgen Inc. Fibroblastenwachstumsfaktor-23-Moleküle und ihre Verwendung
EP1257645A2 (de) * 2000-02-15 2002-11-20 Amgen Inc. Fibroblasten wachstumfaktor-23 moleküle und ihre verwendungen
CN1311212A (zh) * 2000-03-02 2001-09-05 上海博德基因开发有限公司 一种新的多肽——人成纤维细胞生长因子14和编码这种多肽的多核苷酸
DK1286704T3 (da) * 2000-06-02 2014-09-22 Univ Texas Ethylendicystein (EC)-glucose analoge konjugater
US20030045489A1 (en) * 2000-11-22 2003-03-06 Murphy John E. Methods for modulating angiogenesis
FI20011542A7 (fi) * 2001-07-13 2003-01-14 Fit Biotech Oyj Plc Uroginaasigeenin monistuman käyttö
MXPA04012243A (es) 2002-06-07 2005-02-25 Genentech Inc Composiciones y metodos para l diagnostico y tratamiento de tumores.
US20040136970A1 (en) 2002-10-07 2004-07-15 Ellsworth Jeff L. Methods for administering FGF18
US7678373B2 (en) 2006-02-10 2010-03-16 Genentech, Inc. Anti-FGF19 antibodies and methods using same
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
NZ582619A (en) 2007-08-03 2012-08-31 Genentech Inc Humanized anti-fgf19 antagonists and methods using same
US8591455B2 (en) 2008-02-21 2013-11-26 Dexcom, Inc. Systems and methods for customizing delivery of sensor data
MX2010013333A (es) 2008-06-04 2011-04-05 Amgen Inc Mutantes fgf21 y usos de los mismos.
EP2358790B2 (de) 2008-12-16 2016-09-21 Dow Corning Corporation Herstellung von siloxanen
US20120052069A1 (en) 2009-05-05 2012-03-01 Amgen Inc Fgf21 mutants and uses thereof
TWI560197B (en) 2009-05-05 2016-12-01 Amgen Inc Fgf21 mutants and uses thereof
WO2010148142A1 (en) * 2009-06-17 2010-12-23 Amgen Inc. Chimeric fgf19 polypeptides and uses thereof
CN102656266B (zh) * 2009-10-15 2016-08-03 霍夫曼-拉罗奇有限公司 具有改变的受体特异性的嵌合成纤维细胞生长因子
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
TWI670283B (zh) 2013-12-23 2019-09-01 美商建南德克公司 抗體及使用方法
EP3108893A1 (de) * 2015-06-25 2016-12-28 Universite Claude Bernard - Lyon 1 Neuartige therapeutische verwendung von fgf19
KR102315601B1 (ko) 2020-05-13 2021-10-21 전남대학교산학협력단 재조합 벡터 및 이를 이용한 재조합 섬유아세포 성장인자 19의 제조 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014328A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO1999014327A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer
KR100506786B1 (ko) * 1997-11-25 2005-08-08 제넨테크, 인크. 섬유아세포 성장인자-19
MXPA01002545A (es) * 1998-09-10 2005-08-16 Genentech Inc Composiciones y metodos para el tratamiento de tumores.
IL141535A0 (en) * 1998-09-16 2002-03-10 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same

Also Published As

Publication number Publication date
WO1999027100A1 (en) 1999-06-03
CA2309783A1 (en) 1999-06-03
KR100506786B1 (ko) 2005-08-08
EP1032668B1 (de) 2008-05-28
IL193366A0 (en) 2009-02-11
DE69839571D1 (de) 2008-07-10
WO1999027100A9 (en) 2000-05-11
KR20010032405A (ko) 2001-04-16
JP2002503446A (ja) 2002-02-05
KR20050009764A (ko) 2005-01-25
CA2309783C (en) 2011-06-28
IL136055A0 (en) 2001-05-20
AU733222B2 (en) 2001-05-10
DK1032668T3 (da) 2008-09-29
JP3653469B2 (ja) 2005-05-25
NZ504425A (en) 2001-10-26
AU1703399A (en) 1999-06-15
EP1032668A1 (de) 2000-09-06

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Legal Events

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