ATE397073T1 - Menschliche dnase i varianten - Google Patents

Menschliche dnase i varianten

Info

Publication number
ATE397073T1
ATE397073T1 AT96907094T AT96907094T ATE397073T1 AT E397073 T1 ATE397073 T1 AT E397073T1 AT 96907094 T AT96907094 T AT 96907094T AT 96907094 T AT96907094 T AT 96907094T AT E397073 T1 ATE397073 T1 AT E397073T1
Authority
AT
Austria
Prior art keywords
variants
human dnase
dnase
human
Prior art date
Application number
AT96907094T
Other languages
English (en)
Inventor
Robert LAZARUS
Steven Shak
Jana Ulmer
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1995/002366 external-priority patent/WO1996026278A1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE397073T1 publication Critical patent/ATE397073T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96907094T 1995-02-24 1996-02-21 Menschliche dnase i varianten ATE397073T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/002366 WO1996026278A1 (en) 1995-02-24 1995-02-24 HUMAN DNase I VARIANTS
US54052795A 1995-10-10 1995-10-10

Publications (1)

Publication Number Publication Date
ATE397073T1 true ATE397073T1 (de) 2008-06-15

Family

ID=26789529

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96907094T ATE397073T1 (de) 1995-02-24 1996-02-21 Menschliche dnase i varianten

Country Status (20)

Country Link
EP (2) EP0854927B1 (de)
JP (1) JP4549439B2 (de)
AR (1) AR003926A1 (de)
AT (1) ATE397073T1 (de)
AU (1) AU695863B2 (de)
BR (1) BR9607328A (de)
CA (1) CA2211413C (de)
DE (1) DE69637548D1 (de)
DK (1) DK0854927T3 (de)
ES (1) ES2308775T3 (de)
HU (1) HU222665B1 (de)
IL (1) IL117218A (de)
NO (1) NO326616B1 (de)
NZ (1) NZ334762A (de)
PL (1) PL184951B1 (de)
RO (1) RO118886B1 (de)
SI (1) SI9620043A (de)
SK (1) SK284191B6 (de)
TR (1) TR199700842T1 (de)
WO (1) WO1996026279A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391607B1 (en) * 1996-06-14 2002-05-21 Genentech, Inc. Human DNase I hyperactive variants
US9603907B2 (en) * 2012-02-01 2017-03-28 Protalix Ltd. Dry powder formulations of dNase I
HRP20192080T1 (hr) * 2013-10-31 2020-02-07 Resolve Therapeutics, Llc Terapeutske fuzije nukleaza-albumine i postupci
CN104131093B (zh) * 2014-07-23 2015-12-09 哈尔滨工程大学 DNA蛋白结合位点的DNase高通测序检测信号处理方法
US11225648B2 (en) 2015-01-04 2022-01-18 Protalix Ltd. Modified DNase and uses thereof
EP4225903A1 (de) 2020-10-07 2023-08-16 Protalix Ltd. Langwirkende dnase

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511502A (en) 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
WO1987005330A1 (en) 1986-03-07 1987-09-11 Michel Louis Eugene Bergh Method for enhancing glycoprotein stability
EP0449968B1 (de) 1988-12-23 1999-02-24 Genentech, Inc. Verfahren zur herstellung von menschlicher dnase
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I
US5279823A (en) 1992-06-08 1994-01-18 Genentech, Inc. Purified forms of DNASE
CA2147469C (en) 1992-11-02 2008-01-29 Ann L. Daugherty Compaction assay for assessment of respiratory disease therapy
WO1996026278A1 (en) * 1995-02-24 1996-08-29 Genentech, Inc. HUMAN DNase I VARIANTS

Also Published As

Publication number Publication date
CA2211413C (en) 2010-06-22
HU222665B1 (hu) 2003-09-29
NO973877L (no) 1997-10-24
EP0854927B1 (de) 2008-05-28
HUP9702147A2 (hu) 1999-07-28
EP0854927A1 (de) 1998-07-29
CA2211413A1 (en) 1996-08-29
DE69637548D1 (de) 2008-07-10
NO326616B1 (no) 2009-01-19
EP1980618A2 (de) 2008-10-15
NZ334762A (en) 2000-10-27
SK114897A3 (en) 1998-03-04
WO1996026279A1 (en) 1996-08-29
NO973877D0 (no) 1997-08-22
RO118886B1 (ro) 2003-12-30
BR9607328A (pt) 1997-12-30
SK284191B6 (sk) 2004-10-05
DK0854927T3 (da) 2008-09-08
PL184951B1 (pl) 2003-01-31
JPH11503004A (ja) 1999-03-23
AU5026396A (en) 1996-09-11
IL117218A0 (en) 1996-06-18
SI9620043A (sl) 1998-06-30
TR199700842T1 (xx) 1998-01-21
IL117218A (en) 2004-06-01
ES2308775T3 (es) 2008-12-01
AU695863B2 (en) 1998-08-27
PL322002A1 (en) 1998-01-05
AR003926A1 (es) 1998-09-30
HUP9702147A3 (en) 1999-09-28
JP4549439B2 (ja) 2010-09-22

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