ATE397596T1 - Verbessertes verfahren für die kumada- kopplungsreaktion - Google Patents
Verbessertes verfahren für die kumada- kopplungsreaktionInfo
- Publication number
- ATE397596T1 ATE397596T1 AT05855436T AT05855436T ATE397596T1 AT E397596 T1 ATE397596 T1 AT E397596T1 AT 05855436 T AT05855436 T AT 05855436T AT 05855436 T AT05855436 T AT 05855436T AT E397596 T1 ATE397596 T1 AT E397596T1
- Authority
- AT
- Austria
- Prior art keywords
- coupling reaction
- kumada coupling
- improved method
- arylthiophenes
- alkylthiophenes
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000005577 Kumada cross-coupling reaction Methods 0.000 title abstract 2
- JWUJQDFVADABEY-UHFFFAOYSA-N 2-methyltetrahydrofuran Chemical compound CC1CCCO1 JWUJQDFVADABEY-UHFFFAOYSA-N 0.000 abstract 2
- 239000007818 Grignard reagent Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- OHZAHWOAMVVGEL-UHFFFAOYSA-N 2,2'-bithiophene Chemical group C1=CSC(C=2SC=CC=2)=C1 OHZAHWOAMVVGEL-UHFFFAOYSA-N 0.000 abstract 1
- 150000004791 alkyl magnesium halides Chemical class 0.000 abstract 1
- -1 arylmagnesiumhalide Grignard reagent Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000004795 grignard reagents Chemical class 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cosmetics (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Saccharide Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/033,573 US7205414B2 (en) | 2005-01-12 | 2005-01-12 | Process for the Kumada coupling reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE397596T1 true ATE397596T1 (de) | 2008-06-15 |
Family
ID=36178001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05855436T ATE397596T1 (de) | 2005-01-12 | 2005-12-22 | Verbessertes verfahren für die kumada- kopplungsreaktion |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7205414B2 (de) |
| EP (1) | EP1836184B1 (de) |
| JP (1) | JP2008527142A (de) |
| CN (1) | CN101142204A (de) |
| AT (1) | ATE397596T1 (de) |
| CA (1) | CA2594613A1 (de) |
| DE (1) | DE602005007387D1 (de) |
| ES (1) | ES2308603T3 (de) |
| TW (1) | TW200640895A (de) |
| WO (1) | WO2006076150A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9534001B2 (en) * | 2006-03-03 | 2017-01-03 | Chemetall Gmbh | Organomagnesium synthesis agent |
| DE102007026763A1 (de) | 2007-06-09 | 2009-01-15 | Saltigo Gmbh | Verfahren zur Herstellung substituierter Heteroaromaten |
| DE102007033343A1 (de) | 2007-07-09 | 2009-01-15 | Bayer Technology Services Gmbh | Verfahren zur Synthese von Oligo/Polythiophenen nach einem "Eintopf"-Syntheseweg |
| US8679621B2 (en) * | 2010-06-18 | 2014-03-25 | Board Of Trustees Of The University Of Illinois | Materials and methods for autonomous restoration of electrical conductivity |
| CN103880790B (zh) * | 2014-03-13 | 2016-08-24 | 西北大学 | 一种呋喃偶联化合物的合成方法 |
| JP6991584B2 (ja) * | 2015-10-29 | 2022-02-03 | ザ トラスティーズ オブ プリンストン ユニバーシティ | トリ-(アダマンチル)ホスフィンおよびその用途 |
| CN108658929B (zh) * | 2018-06-26 | 2020-11-17 | 宁波人健化学制药有限公司 | 一种高纯度2-(4-氟苯基)噻吩的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5481261A (en) * | 1977-12-06 | 1979-06-28 | Oce Andeno Bv | Manufacture of 33iodothiophene |
| GB8716587D0 (en) * | 1987-07-14 | 1987-08-19 | Shell Int Research | Preparing thiophene derivatives |
| FI93110C (fi) * | 1991-12-09 | 1995-02-27 | Neste Oy | Menetelmä 3-asemassa substituoitujen tiofeenien valmistamiseksi |
| US5371240A (en) * | 1992-11-30 | 1994-12-06 | Torcan Chemical Ltd. | Process for the preparation of pure thiophene derivatives |
| DE19808570C1 (de) | 1998-02-28 | 1999-03-04 | Metallgesellschaft Ag | Benzylmagnesiumhalogenide oder Allylmagnesiumhalogenide enthaltende Synthesemittel und Verfahren zu deren Herstellung |
| FR2800070B1 (fr) * | 1999-10-22 | 2003-08-15 | Sanofi Synthelabo | Procede de preparation d'un derive du thiophene |
| KR20030010508A (ko) * | 2001-07-25 | 2003-02-05 | 메르크 파텐트 게엠베하 | 모노-, 올리고- 및 폴리-4-플루오로티오펜 및 전하 이동물질로서의 이들의 용도 |
-
2005
- 2005-01-12 US US11/033,573 patent/US7205414B2/en not_active Expired - Fee Related
- 2005-12-22 WO PCT/US2005/046872 patent/WO2006076150A1/en not_active Ceased
- 2005-12-22 AT AT05855436T patent/ATE397596T1/de not_active IP Right Cessation
- 2005-12-22 DE DE602005007387T patent/DE602005007387D1/de not_active Expired - Fee Related
- 2005-12-22 ES ES05855436T patent/ES2308603T3/es not_active Expired - Lifetime
- 2005-12-22 CA CA002594613A patent/CA2594613A1/en not_active Abandoned
- 2005-12-22 EP EP05855436A patent/EP1836184B1/de not_active Expired - Lifetime
- 2005-12-22 CN CNA2005800490762A patent/CN101142204A/zh active Pending
- 2005-12-22 JP JP2007551280A patent/JP2008527142A/ja not_active Withdrawn
-
2006
- 2006-01-02 TW TW095100010A patent/TW200640895A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101142204A (zh) | 2008-03-12 |
| TW200640895A (en) | 2006-12-01 |
| EP1836184A1 (de) | 2007-09-26 |
| US20060155134A1 (en) | 2006-07-13 |
| DE602005007387D1 (de) | 2008-07-17 |
| US7205414B2 (en) | 2007-04-17 |
| ES2308603T3 (es) | 2008-12-01 |
| CA2594613A1 (en) | 2006-07-20 |
| EP1836184B1 (de) | 2008-06-04 |
| WO2006076150A1 (en) | 2006-07-20 |
| JP2008527142A (ja) | 2008-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |