ATE397607T1 - Kristall und solvat von 2-amino-6-benzyloxypurin und produktionsverfahren dafür - Google Patents
Kristall und solvat von 2-amino-6-benzyloxypurin und produktionsverfahren dafürInfo
- Publication number
- ATE397607T1 ATE397607T1 AT03745892T AT03745892T ATE397607T1 AT E397607 T1 ATE397607 T1 AT E397607T1 AT 03745892 T AT03745892 T AT 03745892T AT 03745892 T AT03745892 T AT 03745892T AT E397607 T1 ATE397607 T1 AT E397607T1
- Authority
- AT
- Austria
- Prior art keywords
- benzyloxypurine
- solvate
- amino
- crystal
- production method
- Prior art date
Links
- KRWMERLEINMZFT-UHFFFAOYSA-N O6-benzylguanine Chemical compound C=12NC=NC2=NC(N)=NC=1OCC1=CC=CC=C1 KRWMERLEINMZFT-UHFFFAOYSA-N 0.000 title abstract 2
- 239000012453 solvate Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002105805 | 2002-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE397607T1 true ATE397607T1 (de) | 2008-06-15 |
Family
ID=28786402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03745892T ATE397607T1 (de) | 2002-04-08 | 2003-04-03 | Kristall und solvat von 2-amino-6-benzyloxypurin und produktionsverfahren dafür |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7345170B2 (de) |
| EP (1) | EP1492791B1 (de) |
| JP (1) | JP2005522482A (de) |
| AT (1) | ATE397607T1 (de) |
| AU (1) | AU2003226447A1 (de) |
| DE (1) | DE60321457D1 (de) |
| SI (1) | SI1492791T1 (de) |
| WO (1) | WO2003084957A1 (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801710A (en) * | 1984-10-26 | 1989-01-31 | Merck & Co., Inc. | Regioselective synthesis of 9-substituted purine acyclonucleoside derivatives |
| US5352669A (en) * | 1990-03-13 | 1994-10-04 | The Of The United States Of America As Represented By The Department Of Health And Human Services | O6 -benzylated guanine, guanosine and 2'-deoxyguanosine compounds possessing O6 -alkylguanine-DNA alkyltransferase depleting activity |
| US6414112B1 (en) * | 1991-05-24 | 2002-07-02 | Ole Buchardt | Peptide nucleic acids having 2,6-diaminopurine nucleobases |
| JPH06116266A (ja) * | 1992-10-02 | 1994-04-26 | Nippon Kayaku Co Ltd | 2−アミノ−6−アルコキシプリンの製造法 |
| US6184376B1 (en) * | 1997-02-10 | 2001-02-06 | Mediver Ab | Synthesis of acyclic nucleoside derivatives |
| JPH10218880A (ja) * | 1997-02-12 | 1998-08-18 | Sumika Fine Chem Kk | 2−アミノプリン誘導体の製造方法 |
-
2003
- 2003-04-03 WO PCT/JP2003/004258 patent/WO2003084957A1/en not_active Ceased
- 2003-04-03 EP EP03745892A patent/EP1492791B1/de not_active Expired - Lifetime
- 2003-04-03 US US10/500,451 patent/US7345170B2/en not_active Expired - Fee Related
- 2003-04-03 DE DE60321457T patent/DE60321457D1/de not_active Expired - Fee Related
- 2003-04-03 JP JP2003582154A patent/JP2005522482A/ja active Pending
- 2003-04-03 SI SI200331313T patent/SI1492791T1/sl unknown
- 2003-04-03 AU AU2003226447A patent/AU2003226447A1/en not_active Abandoned
- 2003-04-03 AT AT03745892T patent/ATE397607T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003084957A1 (en) | 2003-10-16 |
| SI1492791T1 (sl) | 2008-10-31 |
| US7345170B2 (en) | 2008-03-18 |
| EP1492791A1 (de) | 2005-01-05 |
| US20050080098A1 (en) | 2005-04-14 |
| DE60321457D1 (de) | 2008-07-17 |
| EP1492791B1 (de) | 2008-06-04 |
| JP2005522482A (ja) | 2005-07-28 |
| AU2003226447A1 (en) | 2003-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |