ATE398283T1 - Integrierender sensor mit mehreren wellenleitern - Google Patents

Integrierender sensor mit mehreren wellenleitern

Info

Publication number
ATE398283T1
ATE398283T1 AT00919511T AT00919511T ATE398283T1 AT E398283 T1 ATE398283 T1 AT E398283T1 AT 00919511 T AT00919511 T AT 00919511T AT 00919511 T AT00919511 T AT 00919511T AT E398283 T1 ATE398283 T1 AT E398283T1
Authority
AT
Austria
Prior art keywords
optical signals
waveguides
sensing
waveguide
length
Prior art date
Application number
AT00919511T
Other languages
English (en)
Inventor
Mark Feldstein
Brian Maccraith
Frances Ligler
Original Assignee
Us Gov Sec Navy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Sec Navy filed Critical Us Gov Sec Navy
Application granted granted Critical
Publication of ATE398283T1 publication Critical patent/ATE398283T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Fluid Pressure (AREA)
  • Measurement Of Resistance Or Impedance (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT00919511T 1999-06-21 2000-03-22 Integrierender sensor mit mehreren wellenleitern ATE398283T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/336,729 US6137117A (en) 1999-06-21 1999-06-21 Integrating multi-waveguide sensor

Publications (1)

Publication Number Publication Date
ATE398283T1 true ATE398283T1 (de) 2008-07-15

Family

ID=23317400

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00919511T ATE398283T1 (de) 1999-06-21 2000-03-22 Integrierender sensor mit mehreren wellenleitern

Country Status (8)

Country Link
US (1) US6137117A (de)
EP (1) EP1196760B1 (de)
JP (1) JP2003502660A (de)
KR (1) KR100696237B1 (de)
AT (1) ATE398283T1 (de)
CA (1) CA2375425A1 (de)
DE (1) DE60039172D1 (de)
WO (1) WO2000079240A1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7040653B1 (en) * 2004-10-27 2006-05-09 Automotive Technologies International, Inc. Steering wheel assemblies for vehicles
US20020031836A1 (en) * 2000-09-11 2002-03-14 Feldstein Mark J. Fluidics system
JP2002229728A (ja) * 2001-02-02 2002-08-16 Newcom:Kk Cmosリニアイメージセンサを用いた位置検出装置
EP2169383A1 (de) * 2001-06-15 2010-03-31 Bayer Technology Services GmbH Körper für Durchflussküvetten und deren Verwendung
US6873638B2 (en) * 2001-06-29 2005-03-29 3M Innovative Properties Company Laser diode chip with waveguide
US20030022394A1 (en) * 2001-07-27 2003-01-30 Dumas David P. Biochips and methods of making same
US6767733B1 (en) 2001-10-10 2004-07-27 Pritest, Inc. Portable biosensor apparatus with controlled flow
US20040020993A1 (en) * 2001-12-28 2004-02-05 Green Larry R. Method for luminescent identification and calibration
US6850657B2 (en) * 2002-02-08 2005-02-01 The Research Foundation Of State University Of New York Capillary waveguide fluorescence sensor
US20040060987A1 (en) * 2002-05-07 2004-04-01 Green Larry R. Digital image analysis method for enhanced and optimized signals in fluorophore detection
AU2003258683A1 (en) * 2002-09-03 2004-03-29 Zeptosens Ag Analytical platform and detection method with analytes which are to be detected in a sample in the form of immobilized specific binding partners
FR2846745B1 (fr) * 2002-10-30 2004-12-24 Genewave Dispositif de support d'elements chromophores.
WO2006025866A2 (en) * 2004-03-05 2006-03-09 Creatv Microtech, Inc. Integrated multistep biosensor
JP5296377B2 (ja) 2004-07-02 2013-09-25 バイエル・ヘルスケア・エルエルシー 流体試料中の検体の判定を行うために使用される光導体検査センサ、およびその製作方法
US7496245B2 (en) * 2004-08-20 2009-02-24 Research International, Inc. Misalignment compensating optical sensor and method
US7522786B2 (en) 2005-12-22 2009-04-21 Palo Alto Research Center Incorporated Transmitting light with photon energy information
US7291824B2 (en) * 2005-12-22 2007-11-06 Palo Alto Research Center Incorporated Photosensing throughout energy range and in subranges
US7257279B2 (en) * 2004-09-20 2007-08-14 3M Innovative Properties Company Systems and methods for biosensing and microresonator sensors for same
US7433552B2 (en) * 2005-12-22 2008-10-07 Palo Alto Research Center Incorporated Obtaining analyte information
US7358476B2 (en) * 2005-12-22 2008-04-15 Palo Alto Research Center Incorporated Sensing photons from objects in channels
US7386199B2 (en) * 2005-12-22 2008-06-10 Palo Alto Research Center Incorporated Providing light to channels or portions
US7315667B2 (en) * 2005-12-22 2008-01-01 Palo Alto Research Center Incorporated Propagating light to be sensed
US8437582B2 (en) 2005-12-22 2013-05-07 Palo Alto Research Center Incorporated Transmitting light with lateral variation
US7547904B2 (en) * 2005-12-22 2009-06-16 Palo Alto Research Center Incorporated Sensing photon energies emanating from channels or moving objects
US7420677B2 (en) * 2005-12-22 2008-09-02 Palo Alto Research Center Incorporated Sensing photon energies of optical signals
GR20050100623A (el) * 2005-12-27 2007-07-23 Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων "Δημοκριτος" Βιοαισθητηρες ταυτοχρονης ανιχνευσης πολλαπλων αναλυτων που βασιζονται σε μονολιθικα ολοκληρωμενουσοπτοηλεκτρονικους μεταλλακτες σηματος
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US8675199B2 (en) 2006-03-10 2014-03-18 Plc Diagnostics, Inc. Waveguide-based detection system with scanning light source
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US7454102B2 (en) * 2006-04-26 2008-11-18 Honeywell International Inc. Optical coupling structure
US20080101744A1 (en) * 2006-10-31 2008-05-01 Honeywell International Inc. Optical Waveguide Sensor Devices and Methods For Making and Using Them
EP1918693A1 (de) * 2006-10-31 2008-05-07 Honeywell International, Inc. Optische Wellenleitersensorvorrichtungen und Verfahren zu ihrer Herstellung und Verwendung
US8821799B2 (en) 2007-01-26 2014-09-02 Palo Alto Research Center Incorporated Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity
US9164037B2 (en) 2007-01-26 2015-10-20 Palo Alto Research Center Incorporated Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances
WO2009057024A1 (en) * 2007-10-29 2009-05-07 Koninklijke Philips Electronics N. V. Frustrated total internal reflection biosensor cartridge
US8320983B2 (en) 2007-12-17 2012-11-27 Palo Alto Research Center Incorporated Controlling transfer of objects affecting optical characteristics
US8629981B2 (en) 2008-02-01 2014-01-14 Palo Alto Research Center Incorporated Analyzers with time variation based on color-coded spatial modulation
US8373860B2 (en) 2008-02-01 2013-02-12 Palo Alto Research Center Incorporated Transmitting/reflecting emanating light with time variation
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
US8463083B2 (en) * 2009-01-30 2013-06-11 Claudio Oliveira Egalon Side illuminated multi point multi parameter optical fiber sensor
US8331751B2 (en) * 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US8300993B2 (en) * 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
TW201217783A (en) 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
US9029800B2 (en) 2011-08-09 2015-05-12 Palo Alto Research Center Incorporated Compact analyzer with spatial modulation and multiple intensity modulated excitation sources
US8723140B2 (en) 2011-08-09 2014-05-13 Palo Alto Research Center Incorporated Particle analyzer with spatial modulation and long lifetime bioprobes
JP6573899B2 (ja) 2013-11-17 2019-09-11 クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated 分子をプローブし、検出し、及び分析するための、外部光源を備えた集積デバイス
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
EP2916125A1 (de) * 2014-03-07 2015-09-09 One Drop Diagnostics Sàrl Fluoreszenz-Assays auf mikrofluidischen Chips
EP3194935B1 (de) 2014-08-08 2018-10-31 Quantum-si Incorporated Integrierte vorrichtung zur temporären gruppierung von empfangenen photonen
CN112903639B (zh) 2014-08-08 2022-09-13 宽腾矽公司 用于对分子进行探测、检测和分析的带外部光源的集成装置
WO2016023010A1 (en) 2014-08-08 2016-02-11 Quantum-Si Incorporated Optical system and assay chip for probing, detecting, and analyzing molecules
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
WO2016138427A1 (en) 2015-02-27 2016-09-01 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
WO2016162880A1 (en) * 2015-04-10 2016-10-13 Indian Institute Of Technology Madras A novel ultrasonic waveguide technique for distributed sensing and measurements of physical and chemical properties of surrounding media
TW202139919A (zh) 2016-02-17 2021-11-01 美商太斯萊特健康股份有限公司 用於生命期成像及偵測應用之感測器及裝置
US10845308B2 (en) 2016-12-22 2020-11-24 Quantum-Si Incorporated Integrated photodetector with direct binning pixel
USD811196S1 (en) * 2017-02-15 2018-02-27 Bluewater Resources LLC Transport-container lock
USD811197S1 (en) * 2017-02-15 2018-02-27 Bluewater Resources LLC Transport-container lock
BR112020000826A2 (pt) 2017-07-24 2020-07-21 Quantum-Si Incorporated instrumento bio-optoeletrônico maciçamente paralelo portátil
AU2019288394B2 (en) 2018-06-22 2025-01-30 Quantum-Si Incorporated Integrated photodetector with charge storage bin of varied detection time
US12352894B2 (en) 2022-09-20 2025-07-08 Apple Inc. Wavelength mixing for optical systems

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69526438T2 (de) * 1994-05-27 2002-10-31 Novartis Ag, Basel Verfahren zum nachweis abklingend angeregter lumineszenz
US5671303A (en) * 1996-04-17 1997-09-23 Motorola, Inc. Molecular detection apparatus and method using optical waveguide detection
US5809185A (en) * 1996-04-26 1998-09-15 Mitchell; Ralph Sensor for detecting microorganisms
US5809184A (en) * 1996-10-15 1998-09-15 Doerr; Christopher Richard Polarization diversity waveguide grating receiver

Also Published As

Publication number Publication date
US6137117A (en) 2000-10-24
EP1196760A1 (de) 2002-04-17
JP2003502660A (ja) 2003-01-21
DE60039172D1 (de) 2008-07-24
WO2000079240A1 (en) 2000-12-28
EP1196760A4 (de) 2005-03-02
KR20020015993A (ko) 2002-03-02
KR100696237B1 (ko) 2007-03-20
EP1196760B1 (de) 2008-06-11
CA2375425A1 (en) 2000-12-28

Similar Documents

Publication Publication Date Title
DE60039172D1 (de) Integrierender sensor mit mehreren wellenleitern
EP1348981A3 (de) Verteiltes Laser- Hindernis- Detektionssystem
DE69634660D1 (de) Optischer fluoreszenzsensor
EP3420331B1 (de) Optisches wellenleitersystem für zweidimensionale positionserfassung
FR2656095B1 (fr) Capteur a fibre optique.
DE69006561D1 (de) Doppelkern-Glasfaser als optischer Breitband-Signal-Verstärker.
EP0964251A4 (de) Optische wellenleitersonde und deren herstellungsverfahren
WO2007041507A3 (en) Sensitive emission light gathering and detection system
ATE224537T1 (de) Faserdetektor zur detektion des streulichtes oder des fluoreszenzlichtes einer flüssigen suspension
WO2000077491A3 (en) Fiber optic multitasking probe
EP0620429A4 (de) Optische Messvorrichtung.
DK1029233T3 (da) Måling af koncentrationen af et stof
FR2689632B1 (fr) Detecteur a fibre optique de contraintes.
ATE514209T1 (de) Depolarisierte infrarotlaserstrahlungsquelle
WO2007027540A3 (en) Distributed fiber optic sensor with location capability
FR2706606B1 (fr) Capteur à fibre optique reconfigurable.
NO20015515D0 (no) Langdistanse, heloptisk telemetri for fiberoptisk sensor ved bruk av fjernoptisk pumpede EFDA'er
EP1515135A3 (de) Abbildende Assay-Analyse für Mikroproben
DK0417700T3 (da) Forbedring ved dæmpet total-refleksionsspektroskopi
TW200721022A (en) Apparatus for inputting optical data using optical fiber
WO2006028585A3 (en) Optical fiber bundle for detecting binding of chemical species
DE69824858D1 (de) Kalibriersystem für eine photovervielfacherröhre
TW200517641A (en) Fiber vibration sensor
ATE328295T1 (de) Optisches system
SE9900610D0 (sv) Optoelektronischer Fadensensor

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties