ATE400557T1 - Verfahren zur herstellung von isonikotinsäurederivaten - Google Patents
Verfahren zur herstellung von isonikotinsäurederivatenInfo
- Publication number
- ATE400557T1 ATE400557T1 AT05808264T AT05808264T ATE400557T1 AT E400557 T1 ATE400557 T1 AT E400557T1 AT 05808264 T AT05808264 T AT 05808264T AT 05808264 T AT05808264 T AT 05808264T AT E400557 T1 ATE400557 T1 AT E400557T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- producing
- acid derivatives
- isonicotinic acid
- manufacture
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- TWBYWOBDOCUKOW-UHFFFAOYSA-N isonicotinic acid Chemical class OC(=O)C1=CC=NC=C1 TWBYWOBDOCUKOW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229940123702 Adenosine A2a receptor antagonist Drugs 0.000 abstract 1
- 102100036837 Metabotropic glutamate receptor 2 Human genes 0.000 abstract 1
- 239000002467 adenosine A2a receptor antagonist Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000019522 cellular metabolic process Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 108010038421 metabotropic glutamate receptor 2 Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04105554 | 2004-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE400557T1 true ATE400557T1 (de) | 2008-07-15 |
Family
ID=35695862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05808264T ATE400557T1 (de) | 2004-11-05 | 2005-10-27 | Verfahren zur herstellung von isonikotinsäurederivaten |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7459563B2 (de) |
| EP (1) | EP1812392B1 (de) |
| JP (1) | JP4633123B2 (de) |
| CN (1) | CN101056857B (de) |
| AT (1) | ATE400557T1 (de) |
| CA (1) | CA2586931C (de) |
| DE (1) | DE602005008095D1 (de) |
| ES (1) | ES2309814T3 (de) |
| TW (1) | TW200630340A (de) |
| WO (1) | WO2006048172A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103044324B (zh) * | 2013-01-07 | 2014-05-21 | 湖南宏邦新材料有限公司 | 一种异烟酸酯及其制备方法 |
| CN103848783B (zh) * | 2014-01-14 | 2016-05-04 | 红太阳集团有限公司 | 一种一步氧化合成2-氯烟酸的方法 |
| CN110452165B (zh) * | 2018-05-07 | 2020-09-25 | 新发药业有限公司 | 一种2-甲基吡啶-4-甲酸的制备方法 |
| CN113845502A (zh) * | 2021-11-29 | 2021-12-28 | 山东诚创蓝海医药科技有限公司 | 一种3-（苄氧基）-4-氧代-4h-吡喃-2-羧酸的制备方法 |
| CN121574054B (zh) * | 2026-01-26 | 2026-05-15 | 济南国鼎医药科技有限公司 | 一种2-氟-3-硝基苯甲酸的制备方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH505543A (de) | 1968-11-01 | 1971-04-15 | Ciba Geigy Ag | Schädlingsbekämpfungsmittel |
| NL7109150A (de) | 1970-07-06 | 1972-01-10 | ||
| US4028374A (en) | 1975-11-03 | 1977-06-07 | Morton-Norwich Products, Inc. | Antibacterial thiocyanatobenzothiazoles |
| DE2656468A1 (de) | 1976-12-14 | 1978-06-15 | Boehringer Mannheim Gmbh | N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung |
| US4471957A (en) | 1979-12-03 | 1984-09-18 | Baltimore Therapeutic Equipment Company | Method and apparatus for rehabilitation of damaged limbs |
| DE3374550D1 (en) | 1982-12-21 | 1987-12-23 | Johnsen Jorgensen Plastics Ltd | Dispensing container |
| KR930005004B1 (ko) | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
| FI91859C (fi) | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
| US5348519A (en) | 1988-02-04 | 1994-09-20 | Loredan Biomedical, Inc. | Exercise and diagnostic apparatus and method |
| IL90337A0 (en) | 1988-05-24 | 1989-12-15 | Pfizer | Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents |
| WO1990015801A1 (en) | 1989-06-22 | 1990-12-27 | Pfizer Inc. | Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases |
| EP0427963B1 (de) | 1989-11-10 | 1994-03-30 | Agrolinz Agrarchemikalien Gesellschaft M.B.H. | Verfahren zur Herstellung reiner, unsymmetrisch disubstituierter Harnstoffe |
| US5142910A (en) | 1990-06-27 | 1992-09-01 | Occupational Orthopaedic Systems, Inc. | Dynamic physiological function testing apparatus and method |
| US5275045A (en) | 1991-03-07 | 1994-01-04 | Isotechnologies, Inc. | Apparatus and method for use in assessing the lifting capability of a human subject |
| JP2759228B2 (ja) | 1992-05-21 | 1998-05-28 | 株式会社大塚製薬工場 | ホスホン酸ジエステル誘導体 |
| US5312107A (en) | 1993-05-13 | 1994-05-17 | Kordun, Ltd. | Golf club swing training and exercise device |
| FR2753970B1 (fr) | 1996-10-01 | 1998-10-30 | Synthelabo | Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique |
| NZ503491A (en) | 1997-11-10 | 2002-08-28 | Bristol Myers Squibb Co | 2-substituted amino-1,3-benzothiazole derivatives useful as protein tyrosine kinase inhibitors |
| CA2318969A1 (en) | 1998-01-23 | 1999-07-29 | Mikhail F. Gordeev | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| CN1325397A (zh) | 1998-09-30 | 2001-12-05 | 纽罗根公司 | 2－哌嗪烷基氨基苯并吡咯衍生物∶多巴胺受体亚型特异配体 |
| UA71587C2 (uk) | 1998-11-10 | 2004-12-15 | Шерінг Акцієнгезелльшафт | Аміди антранілової кислоти та їхнє застосування як лікарських засобів |
| AU6420700A (en) | 1999-08-05 | 2001-03-05 | Prescient Neuropharma Inc. | Novel 1,4-benzodiazepine compounds and derivatives thereof |
| IL133680A0 (en) | 1999-09-10 | 2001-04-30 | Can Fite Technologies Ltd | Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist |
| TR200201023T2 (tr) | 1999-10-15 | 2002-09-23 | F. Hoffmann-La Roche Ag | Benzodiazepin türevleri. |
| AU779874B2 (en) | 1999-10-15 | 2005-02-17 | F. Hoffmann-La Roche Ag | Benzodiazepine derivatives |
| RU2251419C2 (ru) | 2000-06-21 | 2005-05-10 | Ф. Хоффманн-Ля Рош Аг | Производные бензотиазола |
| HRP20030791B1 (en) | 2001-04-12 | 2006-06-30 | F. Hoffmann - La Roche Ag | DIHYDRO-BENZO[b][1,4]DIAZEPIN-2-ONE DERIVATIVES AS mGluR2 ANTAGONISTS I |
| US6620811B2 (en) * | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
-
2005
- 2005-10-27 EP EP05808264A patent/EP1812392B1/de not_active Expired - Lifetime
- 2005-10-27 AT AT05808264T patent/ATE400557T1/de not_active IP Right Cessation
- 2005-10-27 DE DE602005008095T patent/DE602005008095D1/de not_active Expired - Lifetime
- 2005-10-27 ES ES05808264T patent/ES2309814T3/es not_active Expired - Lifetime
- 2005-10-27 WO PCT/EP2005/011491 patent/WO2006048172A1/en not_active Ceased
- 2005-10-27 JP JP2007539508A patent/JP4633123B2/ja not_active Expired - Fee Related
- 2005-10-27 US US11/259,880 patent/US7459563B2/en not_active Expired - Fee Related
- 2005-10-27 CN CN2005800380870A patent/CN101056857B/zh not_active Expired - Fee Related
- 2005-10-27 CA CA2586931A patent/CA2586931C/en not_active Expired - Fee Related
- 2005-11-03 TW TW094138643A patent/TW200630340A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2586931A1 (en) | 2006-05-11 |
| JP4633123B2 (ja) | 2011-02-16 |
| JP2008518991A (ja) | 2008-06-05 |
| CA2586931C (en) | 2013-08-06 |
| US7459563B2 (en) | 2008-12-02 |
| US20060100440A1 (en) | 2006-05-11 |
| TW200630340A (en) | 2006-09-01 |
| ES2309814T3 (es) | 2008-12-16 |
| EP1812392B1 (de) | 2008-07-09 |
| DE602005008095D1 (de) | 2008-08-21 |
| CN101056857A (zh) | 2007-10-17 |
| EP1812392A1 (de) | 2007-08-01 |
| WO2006048172A1 (en) | 2006-05-11 |
| CN101056857B (zh) | 2010-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ599342A (en) | Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors | |
| TNSN05194A1 (en) | Substituted n-arylheterocycles, method for production and use thereof as medicaments | |
| SG166019A1 (en) | Quinoline derivatives and use thereof as mycobacterial inhibitors | |
| TW200718424A (en) | Novel compounds of amino sulfonyl derivatives | |
| WO2008094992A3 (en) | 2-aminopyridine derivatives useful as kinase inhibitors | |
| ATE533773T1 (de) | Phosphor-haltige heptazinderivate, verfahren zu deren herstellung und deren verwendung als flammschutzmittel | |
| NZ562235A (en) | Benzimidazole and pyridoimidazole derivatives as CRF receptor antagonists, for treating affective disorder, depression, or anxiety | |
| TW200637863A (en) | Organic compounds | |
| MX2009011059A (es) | Aminopirimidinas utiles como inhibidores de cinasas. | |
| NO20050134L (no) | Difenylazetidioner substituert med syregrupper, fremgangsmate for fremstilling av disse, medikamenter inneholdende disse forbindelser og deres anvendelse | |
| TW200630366A (en) | Organic compounds | |
| TNSN07006A1 (en) | Novel heterocyclic compounds | |
| MA27232A1 (fr) | Derives d'acide n-benzoylureidocinnamique, leurs procedes de preparation et leurs utilisations | |
| IL181196A0 (en) | Methods for the production of isoindole derivatives | |
| DE602005008095D1 (de) | Verfahren zur herstellung von isonikotinsäurederivaten | |
| ATE532516T1 (de) | Verfahren zur synthese von glyt-1-hemmern | |
| TW200606153A (en) | Process for producing pyridine derivatives of Nk-1 receptor antagonist | |
| PL1745010T3 (pl) | Podstawione pochodne cykloheksylo-1,4-diaminy | |
| TW200635905A (en) | Processes for producing 4-aminoquinazolines | |
| TW200621223A (en) | Acyclic 1,3-diamines and uses therefor | |
| ATE489367T1 (de) | Verfahren und zwischenprodukt zur herstellung von donezepil | |
| CY1109717T1 (el) | Παραγωγα 5-πυριδινυλιο-1-αζαδικυκλο[3.2.1]οκτανιο, μεθοδος παρασκευης και η εφαρμογη τους στη θεραπευτικη | |
| ZA200804858B (en) | Sulfoximine derivatives as p38 map kinase inhibitors | |
| TW200616624A (en) | 2-substituted-1-deaza purine derivatives with adenosine receptor modulating activity | |
| MY137599A (en) | 6-substituted pyridoindolone derivatives, their preparation and their application in therapeutics |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |