ATE40116T1 - 1-acyl-3-pyridylmethylguanidine und deren verwendung als antihypertensiva. - Google Patents
1-acyl-3-pyridylmethylguanidine und deren verwendung als antihypertensiva.Info
- Publication number
- ATE40116T1 ATE40116T1 AT83902866T AT83902866T ATE40116T1 AT E40116 T1 ATE40116 T1 AT E40116T1 AT 83902866 T AT83902866 T AT 83902866T AT 83902866 T AT83902866 T AT 83902866T AT E40116 T1 ATE40116 T1 AT E40116T1
- Authority
- AT
- Austria
- Prior art keywords
- acyl
- pyridylmethylguanidine
- antihypertensives
- guanidine
- pyridylalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/410,959 US4496573A (en) | 1982-08-24 | 1982-08-24 | 1-Pyridylmethyl-3-acyl guanidines |
| PCT/US1983/001287 WO1984000963A1 (en) | 1982-08-24 | 1983-08-23 | 1-acyl-3-pyridylguanidines and their use as antihypertensive agents |
| EP83902866A EP0116628B1 (de) | 1982-08-24 | 1983-08-23 | 1-acyl-3-pyridylmethylguanidine und deren verwendung als antihypertensiva |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE40116T1 true ATE40116T1 (de) | 1989-02-15 |
Family
ID=23626973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83902866T ATE40116T1 (de) | 1982-08-24 | 1983-08-23 | 1-acyl-3-pyridylmethylguanidine und deren verwendung als antihypertensiva. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4496573A (de) |
| EP (1) | EP0116628B1 (de) |
| JP (1) | JPS59501715A (de) |
| AT (1) | ATE40116T1 (de) |
| AU (1) | AU1946983A (de) |
| DE (1) | DE3378979D1 (de) |
| WO (1) | WO1984000963A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05294935A (ja) * | 1991-03-15 | 1993-11-09 | Green Cross Corp:The | アミノピリジン系化合物 |
| US5371086A (en) * | 1991-03-15 | 1994-12-06 | The Green Cross Corporation | Aminopyridine compounds |
| BRPI0411900B8 (pt) * | 2003-06-26 | 2021-05-25 | Biotron Ltd | compostos e composições farmacêuticas compreendendo os mesmos |
| US20070099968A1 (en) * | 2004-06-26 | 2007-05-03 | Biotron Limited | Antiviral compounds and methods |
| US8399443B2 (en) | 2009-04-22 | 2013-03-19 | Mercator Medsystems, Inc. | Treatment of hypertension by renal vascular delivery of guanethidine |
| EP2768514B8 (de) * | 2011-10-19 | 2019-06-19 | Mercator Medsystems, Inc. | Lokalisierte modulation von gewebe und zellen zur verbesserung der therapeutischen wirkung einschliesslich nierendenervierung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3914306A (en) * | 1972-09-22 | 1975-10-21 | Rorer Inc William H | Guanidines |
| GB1461806A (en) * | 1974-03-05 | 1977-01-19 | Wyeth John & Brother Ltd | Pyridine derivatives |
| DE2728423A1 (de) * | 1977-06-24 | 1979-01-04 | Grote & Hartmann | Federkabelschuh |
| NL8000869A (nl) * | 1979-02-16 | 1980-08-19 | Eisai Co Ltd | Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan. |
| US4246406A (en) * | 1979-03-27 | 1981-01-20 | Merck & Co., Inc. | Heterocyclic substituted pyrazinoylguanidines |
-
1982
- 1982-08-24 US US06/410,959 patent/US4496573A/en not_active Expired - Fee Related
-
1983
- 1983-08-23 DE DE8383902866T patent/DE3378979D1/de not_active Expired
- 1983-08-23 WO PCT/US1983/001287 patent/WO1984000963A1/en not_active Ceased
- 1983-08-23 AT AT83902866T patent/ATE40116T1/de not_active IP Right Cessation
- 1983-08-23 JP JP83502941A patent/JPS59501715A/ja active Pending
- 1983-08-23 AU AU19469/83A patent/AU1946983A/en not_active Abandoned
- 1983-08-23 EP EP83902866A patent/EP0116628B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0116628A4 (de) | 1985-02-18 |
| DE3378979D1 (en) | 1989-02-23 |
| EP0116628B1 (de) | 1989-01-18 |
| AU1946983A (en) | 1984-03-29 |
| JPS59501715A (ja) | 1984-10-11 |
| US4496573A (en) | 1985-01-29 |
| EP0116628A1 (de) | 1984-08-29 |
| WO1984000963A1 (en) | 1984-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |