ATE401416T1 - Verfahren zur herstellung von optisch aktiver n- geschützten propargylglycine - Google Patents
Verfahren zur herstellung von optisch aktiver n- geschützten propargylglycineInfo
- Publication number
- ATE401416T1 ATE401416T1 AT06251462T AT06251462T ATE401416T1 AT E401416 T1 ATE401416 T1 AT E401416T1 AT 06251462 T AT06251462 T AT 06251462T AT 06251462 T AT06251462 T AT 06251462T AT E401416 T1 ATE401416 T1 AT E401416T1
- Authority
- AT
- Austria
- Prior art keywords
- genus
- propargylglycine
- protected
- producing
- following formula
- Prior art date
Links
- -1 N-PROTECTED PROPARGYLGLYCINE Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 239000004382 Amylase Substances 0.000 abstract 1
- 241000228212 Aspergillus Species 0.000 abstract 1
- 241000194108 Bacillus licheniformis Species 0.000 abstract 1
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 241001453380 Burkholderia Species 0.000 abstract 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- 241000223198 Humicola Species 0.000 abstract 1
- 241000228143 Penicillium Species 0.000 abstract 1
- 241000589516 Pseudomonas Species 0.000 abstract 1
- 241000235527 Rhizopus Species 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 241000223257 Thermomyces Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005081364A JP4765358B2 (ja) | 2005-03-22 | 2005-03-22 | 光学活性なn−保護−プロパルギルグリシンの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401416T1 true ATE401416T1 (de) | 2008-08-15 |
Family
ID=36636950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06251462T ATE401416T1 (de) | 2005-03-22 | 2006-03-20 | Verfahren zur herstellung von optisch aktiver n- geschützten propargylglycine |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7645607B2 (de) |
| EP (1) | EP1705252B1 (de) |
| JP (1) | JP4765358B2 (de) |
| AT (1) | ATE401416T1 (de) |
| DE (1) | DE602006001769D1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107089928A (zh) * | 2017-05-07 | 2017-08-25 | 济南同路医药科技发展有限公司 | N‑Boc‑L‑炔丙基甘氨酸的合成方法 |
| EP4615988A1 (de) * | 2022-11-11 | 2025-09-17 | Genentech Inc. | Enzymatische asymmetrische synthese von n-alkylaminosäuren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5816876B2 (ja) * | 1975-04-28 | 1983-04-02 | 武田薬品工業株式会社 | コウガクカツセイアミノサンルイノセイゾウホウ |
| JPH01257484A (ja) * | 1987-12-14 | 1989-10-13 | Idemitsu Kosan Co Ltd | 光学活性な二級アルコールの製造方法 |
| US5508466A (en) * | 1994-04-13 | 1996-04-16 | G.D. Searle & Co. | Synthesis of N-protected-α-substituted-glycine racemic esters by zinc-mediated addition of organic halide to glycine cation equivalent |
| JP3160879B2 (ja) * | 1996-01-30 | 2001-04-25 | 田辺製薬株式会社 | 光学活性アミノ酸誘導体の製法 |
| JP3744171B2 (ja) * | 1997-01-24 | 2006-02-08 | 住友化学株式会社 | 光学活性n−置換アゼチジン−2−カルボン酸化合物の製造方法 |
| JP4042454B2 (ja) * | 2002-04-10 | 2008-02-06 | 住友化学株式会社 | 光学活性3−メチルグルタル酸モノエステルの製造方法 |
-
2005
- 2005-03-22 JP JP2005081364A patent/JP4765358B2/ja not_active Expired - Fee Related
-
2006
- 2006-03-20 DE DE602006001769T patent/DE602006001769D1/de not_active Expired - Lifetime
- 2006-03-20 AT AT06251462T patent/ATE401416T1/de not_active IP Right Cessation
- 2006-03-20 EP EP06251462A patent/EP1705252B1/de not_active Expired - Lifetime
- 2006-03-20 US US11/378,366 patent/US7645607B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006262710A (ja) | 2006-10-05 |
| JP4765358B2 (ja) | 2011-09-07 |
| US7645607B2 (en) | 2010-01-12 |
| EP1705252B1 (de) | 2008-07-16 |
| EP1705252A1 (de) | 2006-09-27 |
| US20060216806A1 (en) | 2006-09-28 |
| DE602006001769D1 (de) | 2008-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |