ATE401885T1 - Nikotinhaltige zusammensetzung mit gesteuerter freisetzung und verfahren - Google Patents
Nikotinhaltige zusammensetzung mit gesteuerter freisetzung und verfahrenInfo
- Publication number
- ATE401885T1 ATE401885T1 AT03724037T AT03724037T ATE401885T1 AT E401885 T1 ATE401885 T1 AT E401885T1 AT 03724037 T AT03724037 T AT 03724037T AT 03724037 T AT03724037 T AT 03724037T AT E401885 T1 ATE401885 T1 AT E401885T1
- Authority
- AT
- Austria
- Prior art keywords
- nicotine
- aqueous solution
- functional groups
- product
- cation exchange
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 7
- 229960002715 nicotine Drugs 0.000 title abstract 7
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title 1
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 3
- 230000002378 acidificating effect Effects 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 239000003729 cation exchange resin Substances 0.000 abstract 3
- 125000000524 functional group Chemical group 0.000 abstract 3
- 229920005862 polyol Polymers 0.000 abstract 3
- 150000003077 polyols Chemical class 0.000 abstract 3
- 239000011347 resin Substances 0.000 abstract 3
- 229920005989 resin Polymers 0.000 abstract 3
- 239000004793 Polystyrene Substances 0.000 abstract 2
- 229920002223 polystyrene Polymers 0.000 abstract 2
- 238000005342 ion exchange Methods 0.000 abstract 1
- 125000005395 methacrylic acid group Chemical group 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Addiction (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/166,236 US6586449B1 (en) | 2002-05-28 | 2002-05-28 | Nicotine-containing, controlled release composition and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401885T1 true ATE401885T1 (de) | 2008-08-15 |
Family
ID=22602397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03724037T ATE401885T1 (de) | 2002-05-28 | 2003-04-15 | Nikotinhaltige zusammensetzung mit gesteuerter freisetzung und verfahren |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6586449B1 (de) |
| EP (1) | EP1549633B1 (de) |
| AT (1) | ATE401885T1 (de) |
| CY (1) | CY1108411T1 (de) |
| DE (2) | DE03724037T1 (de) |
| DK (1) | DK1549633T3 (de) |
| ES (1) | ES2285969T3 (de) |
| PT (1) | PT1549633E (de) |
| SI (1) | SI1549633T1 (de) |
| WO (1) | WO2003101982A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| ATE485837T1 (de) * | 2000-08-03 | 2010-11-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
| SE521512C2 (sv) | 2001-06-25 | 2003-11-11 | Niconovum Ab | Anordning för administrering av en substans till främre delen av en individs munhåla |
| PT1578422E (pt) * | 2002-12-20 | 2007-06-14 | Niconovum Ab | Material particulado contendo nicotina fisicamente e quimicamente estável |
| ATE534373T1 (de) | 2003-10-10 | 2011-12-15 | Antares Pharma Ipl Ag | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
| US7387788B1 (en) | 2003-10-10 | 2008-06-17 | Antares Pharma Ipl Ag | Pharmaceutical compositions of nicotine and methods of use thereof |
| WO2005053691A2 (en) * | 2003-12-02 | 2005-06-16 | Fertin Pharma A/S | Nicotine delivery product and method for producing it |
| US7425340B2 (en) | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
| US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
| WO2006128468A1 (en) * | 2005-06-01 | 2006-12-07 | Fertin Pharma A/S | A method of manufacturing a nicotine delivery product |
| KR100699582B1 (ko) | 2005-07-11 | 2007-03-23 | 삼성전기주식회사 | 출력 버퍼회로 |
| AU2007224584A1 (en) | 2006-03-16 | 2007-09-20 | Niconovum Ab | Improved snuff composition |
| CN101426475A (zh) | 2006-04-21 | 2009-05-06 | 安塔雷斯制药Ipl股份公司 | 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法 |
| US20070286903A1 (en) * | 2006-06-13 | 2007-12-13 | Becicka Brian T | Composition and method for taste masking |
| US8642016B2 (en) * | 2006-07-21 | 2014-02-04 | Jsrnti, Llc | Medicinal delivery system, and related methods |
| US9125434B2 (en) | 2007-10-11 | 2015-09-08 | Philip Morris Products S.A. | Smokeless tobacco product, smokeless tobacco product in the form of a sheet, extrudable tobacco composition, method for manufacturing a smokeless tobacco product, method for delivering super bioavailable nicotine contained in tobacco to a user, and packaged smokeless tobacco product sheet |
| WO2009048522A1 (en) * | 2007-10-11 | 2009-04-16 | Richard Fuisz | Smokeless tobacco product |
| DK2198865T3 (da) | 2008-12-19 | 2012-01-16 | Siegfried Ltd | Nikotinholdigt produkt |
| US8728444B2 (en) | 2010-05-31 | 2014-05-20 | Fertin Pharma A/S | Formulation comprising nicotine and a cation exchange resin |
| WO2011150959A1 (en) * | 2010-05-31 | 2011-12-08 | Fertin Pharma A/S | Formulation comprising nicotine and a cation exchange resin |
| US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US9763928B2 (en) | 2012-02-10 | 2017-09-19 | Niconovum Usa, Inc. | Multi-layer nicotine-containing pharmaceutical composition |
| US9044035B2 (en) | 2012-04-17 | 2015-06-02 | R.J. Reynolds Tobacco Company | Remelted ingestible products |
| ES2814296T3 (es) | 2016-04-21 | 2021-03-26 | Fertin Pharma As | Producto para administración de nicotina, usos relacionados y formas de dosificación oral y métodos de producción |
| US20220151292A1 (en) * | 2020-11-16 | 2022-05-19 | Ncp Nextgen A/S | Nicotine pouch composition |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3901248A (en) * | 1970-07-22 | 1975-08-26 | Leo Ab | Chewable smoking substitute composition |
| US3845217A (en) * | 1972-11-16 | 1974-10-29 | Helsingborg L Ab | Buffered smoking substitute compositions |
| US4692462A (en) * | 1985-03-18 | 1987-09-08 | Menley & James Laboratories, Ltd. | Compositions and method of controlling transdermal penetration of topical and systemic agents |
| AU5354994A (en) * | 1992-10-15 | 1994-05-09 | Alza Corporation | Delayed onset transdermal delivery device |
| GB9310412D0 (en) * | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
-
2002
- 2002-05-28 US US10/166,236 patent/US6586449B1/en not_active Expired - Lifetime
-
2003
- 2003-04-15 AT AT03724037T patent/ATE401885T1/de active
- 2003-04-15 ES ES03724037T patent/ES2285969T3/es not_active Expired - Lifetime
- 2003-04-15 DE DE03724037T patent/DE03724037T1/de active Pending
- 2003-04-15 PT PT03724037T patent/PT1549633E/pt unknown
- 2003-04-15 EP EP03724037A patent/EP1549633B1/de not_active Revoked
- 2003-04-15 DK DK03724037T patent/DK1549633T3/da active
- 2003-04-15 WO PCT/US2003/011607 patent/WO2003101982A1/en not_active Ceased
- 2003-04-15 DE DE60322405T patent/DE60322405D1/de not_active Expired - Lifetime
- 2003-04-15 SI SI200331402T patent/SI1549633T1/sl unknown
- 2003-05-05 US US10/429,420 patent/US6828336B2/en not_active Expired - Lifetime
-
2008
- 2008-10-13 CY CY20081101133T patent/CY1108411T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1549633T1 (sl) | 2009-02-28 |
| EP1549633A1 (de) | 2005-07-06 |
| EP1549633A4 (de) | 2007-04-04 |
| US6586449B1 (en) | 2003-07-01 |
| ES2285969T3 (es) | 2008-12-16 |
| CY1108411T1 (el) | 2014-02-12 |
| DK1549633T3 (da) | 2008-10-06 |
| US6828336B2 (en) | 2004-12-07 |
| ES2285969T1 (es) | 2007-12-01 |
| EP1549633B1 (de) | 2008-07-23 |
| WO2003101982A1 (en) | 2003-12-11 |
| US20030224048A1 (en) | 2003-12-04 |
| DE60322405D1 (de) | 2008-09-04 |
| DE03724037T1 (de) | 2007-10-11 |
| PT1549633E (pt) | 2008-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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