ATE402928T1 - Sulphonamidverbindungen, die die chemokinrezeptoraktivität (ccr4) modulieren - Google Patents
Sulphonamidverbindungen, die die chemokinrezeptoraktivität (ccr4) modulierenInfo
- Publication number
- ATE402928T1 ATE402928T1 AT04748975T AT04748975T ATE402928T1 AT E402928 T1 ATE402928 T1 AT E402928T1 AT 04748975 T AT04748975 T AT 04748975T AT 04748975 T AT04748975 T AT 04748975T AT E402928 T1 ATE402928 T1 AT E402928T1
- Authority
- AT
- Austria
- Prior art keywords
- ccr4
- chemokine receptor
- receptor activity
- modulate chemokine
- sulphonamide compounds
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title 1
- 108050000299 Chemokine receptor Proteins 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D241/22—Benzenesulfonamido pyrazines
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- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301653A SE0301653D0 (sv) | 2003-06-05 | 2003-06-05 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE402928T1 true ATE402928T1 (de) | 2008-08-15 |
Family
ID=29212392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04748975T ATE402928T1 (de) | 2003-06-05 | 2004-06-02 | Sulphonamidverbindungen, die die chemokinrezeptoraktivität (ccr4) modulieren |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060122195A1 (de) |
| EP (1) | EP1633729B1 (de) |
| JP (1) | JP2006526618A (de) |
| AR (1) | AR044614A1 (de) |
| AT (1) | ATE402928T1 (de) |
| DE (1) | DE602004015451D1 (de) |
| ES (1) | ES2309539T3 (de) |
| SE (1) | SE0301653D0 (de) |
| TW (1) | TW200505875A (de) |
| UY (1) | UY28348A1 (de) |
| WO (1) | WO2004108692A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI328007B (en) * | 2002-01-16 | 2010-08-01 | Astrazeneca Ab | Novel compounds |
| SE0301650D0 (sv) * | 2003-06-04 | 2003-06-04 | Astrazeneca Ab | Novel compounds |
| SE0301654D0 (sv) * | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
| ZA200709817B (en) | 2005-04-21 | 2009-02-25 | Serono Lab | 2,3 substituted pyrazine sulfonmides as inhibitors of CRTH2 |
| PL1891075T3 (pl) | 2005-05-24 | 2011-12-30 | Merck Serono Sa | Spiropochodne tricykliczne jako modulatory CRTH2 |
| TW200745060A (en) * | 2005-09-19 | 2007-12-16 | Astrazeneca Ab | Novel process |
| TW200800921A (en) * | 2005-09-19 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
| WO2007063934A1 (ja) * | 2005-12-02 | 2007-06-07 | Mitsubishi Tanabe Pharma Corporation | 脂環式複素環化合物 |
| WO2007063935A1 (ja) * | 2005-12-02 | 2007-06-07 | Mitsubishi Tanabe Pharma Corporation | 芳香族化合物 |
| TW200730512A (en) * | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
| US7829709B1 (en) | 2007-08-10 | 2010-11-09 | Marquette University | Cysteine prodrugs to treat schizophrenia and drug addiction |
| GB0718167D0 (en) | 2007-09-18 | 2007-10-31 | Cancer Rec Tech Ltd | Cancer marker and therapeutic target |
| US8173809B2 (en) | 2008-02-07 | 2012-05-08 | Marquette University | Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings |
| JP5658137B2 (ja) * | 2008-04-16 | 2015-01-21 | マーケット ユニバーシティー | 統合失調症又は薬物渇望治療用医薬組成物 |
| JP5785560B2 (ja) | 2009-12-21 | 2015-09-30 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 殺真菌剤としてのビス(ジフルオロメチル)ピラゾール |
| US8815775B2 (en) | 2010-05-18 | 2014-08-26 | Bayer Cropscience Ag | Bis(difluoromethyl)pyrazoles as fungicides |
| RU2627268C2 (ru) | 2012-02-29 | 2017-08-04 | Хемоцентрикс, Инк. | Аза-арил-1Н-пиразол-1-ил-сульфонамиды |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| JP6602779B2 (ja) | 2014-02-13 | 2019-11-06 | インサイト・コーポレイション | Lsd1阻害剤としてのシクロプロピルアミン類 |
| EP3105219B9 (de) | 2014-02-13 | 2018-10-03 | Incyte Corporation | Cyclopropylamine als lsd1-hemmer |
| EP3105218B1 (de) | 2014-02-13 | 2019-09-25 | Incyte Corporation | Cyclopropylamine als lsd1-hemmer |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| WO2016007731A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyridines and imidazopyrazines as lsd1 inhibitors |
| US9758523B2 (en) | 2014-07-10 | 2017-09-12 | Incyte Corporation | Triazolopyridines and triazolopyrazines as LSD1 inhibitors |
| US9695180B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors |
| WO2016057424A1 (en) | 2014-10-06 | 2016-04-14 | Chemocentryx, Inc. | Combination therapy of inhibitors of c-c chemokine receptor type 9 (ccr9) and anti-alha4beta7 integrin blocking antibodies |
| EP3277689B1 (de) | 2015-04-03 | 2019-09-04 | Incyte Corporation | Heterocyclische verbindungen als lsd1-hemmer |
| MY189367A (en) | 2015-08-12 | 2022-02-08 | Incyte Corp | Salts of an lsd1 inhibitor |
| TWI833686B (zh) | 2016-04-22 | 2024-03-01 | 美商英塞特公司 | Lsd1 抑制劑之調配物 |
| EP3706750A1 (de) | 2017-11-06 | 2020-09-16 | RAPT Therapeutics, Inc. | Chemokinrezeptor-modulatoren zur behandlung von epstein-barr-virus-positivem krebs |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| US10792360B1 (en) | 2019-11-21 | 2020-10-06 | Chemocentryx, Inc. | Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962490A (en) * | 1987-09-25 | 1999-10-05 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| GB9512697D0 (en) * | 1995-06-22 | 1995-08-23 | Zeneca Ltd | Heterocyclic compounds |
| US7091201B2 (en) * | 2000-09-25 | 2006-08-15 | Actelion Pharmaceuticals Ltd. | Arylalkane-sulfonamides having endothelin-antagonist activity |
| US20020132836A1 (en) * | 2000-10-11 | 2002-09-19 | Chemocentryx Inc. | Compounds and methods for modulating CCR4 function |
| AU2002358390A1 (en) * | 2001-12-18 | 2003-06-30 | Astrazeneca Ab | Novel compounds |
| TWI328007B (en) * | 2002-01-16 | 2010-08-01 | Astrazeneca Ab | Novel compounds |
| AU2003252478A1 (en) * | 2002-07-10 | 2004-02-02 | Ono Pharmaceutical Co., Ltd. | Ccr4 antagonist and medicinal use thereof |
| SE0301650D0 (sv) * | 2003-06-04 | 2003-06-04 | Astrazeneca Ab | Novel compounds |
| SE0301654D0 (sv) * | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
-
2003
- 2003-06-05 SE SE0301653A patent/SE0301653D0/xx unknown
-
2004
- 2004-05-27 TW TW093115166A patent/TW200505875A/zh unknown
- 2004-06-02 US US10/559,312 patent/US20060122195A1/en not_active Abandoned
- 2004-06-02 DE DE602004015451T patent/DE602004015451D1/de not_active Expired - Fee Related
- 2004-06-02 WO PCT/SE2004/000850 patent/WO2004108692A1/en not_active Ceased
- 2004-06-02 AT AT04748975T patent/ATE402928T1/de not_active IP Right Cessation
- 2004-06-02 ES ES04748975T patent/ES2309539T3/es not_active Expired - Lifetime
- 2004-06-02 EP EP04748975A patent/EP1633729B1/de not_active Expired - Lifetime
- 2004-06-02 JP JP2006508570A patent/JP2006526618A/ja active Pending
- 2004-06-04 UY UY28348A patent/UY28348A1/es not_active Application Discontinuation
- 2004-06-04 AR ARP040101943A patent/AR044614A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY28348A1 (es) | 2005-01-31 |
| JP2006526618A (ja) | 2006-11-24 |
| EP1633729B1 (de) | 2008-07-30 |
| DE602004015451D1 (de) | 2008-09-11 |
| WO2004108692A1 (en) | 2004-12-16 |
| TW200505875A (en) | 2005-02-16 |
| AR044614A1 (es) | 2005-09-21 |
| SE0301653D0 (sv) | 2003-06-05 |
| EP1633729A1 (de) | 2006-03-15 |
| ES2309539T3 (es) | 2008-12-16 |
| US20060122195A1 (en) | 2006-06-08 |
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