ATE403419T1 - Mikrokapseln mit extern ausgelöster öffnung - Google Patents

Mikrokapseln mit extern ausgelöster öffnung

Info

Publication number
ATE403419T1
ATE403419T1 AT99923048T AT99923048T ATE403419T1 AT E403419 T1 ATE403419 T1 AT E403419T1 AT 99923048 T AT99923048 T AT 99923048T AT 99923048 T AT99923048 T AT 99923048T AT E403419 T1 ATE403419 T1 AT E403419T1
Authority
AT
Austria
Prior art keywords
drug
micro capsules
externally triggered
heated
polymer shell
Prior art date
Application number
AT99923048T
Other languages
English (en)
Inventor
Dennis Morrison
Benjamin Mosier
Original Assignee
Nasa Johnson Space Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nasa Johnson Space Ct filed Critical Nasa Johnson Space Ct
Application granted granted Critical
Publication of ATE403419T1 publication Critical patent/ATE403419T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
AT99923048T 1998-05-15 1999-05-14 Mikrokapseln mit extern ausgelöster öffnung ATE403419T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7975898A 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
ATE403419T1 true ATE403419T1 (de) 2008-08-15

Family

ID=22152620

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923048T ATE403419T1 (de) 1998-05-15 1999-05-14 Mikrokapseln mit extern ausgelöster öffnung

Country Status (5)

Country Link
EP (1) EP1077686B1 (de)
AT (1) ATE403419T1 (de)
DE (1) DE69939258D1 (de)
ES (1) ES2310938T3 (de)
WO (1) WO1999059556A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10025803A1 (de) * 2000-05-24 2001-12-20 Jms Co Ltd Polymeroberfläche mit biologisch aktiven Eigenschaften und Verfahren zu ihrer Herstellung
DE10141674A1 (de) 2000-09-01 2002-03-14 Henkel Kgaa Reaktionsklebstoff mit mindestens einer mikroverkapselten Komponente
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US7264629B2 (en) 2001-11-09 2007-09-04 Qlt, Inc. Photodynamic therapy for the treatment of hair loss
JP2005514346A (ja) * 2001-11-09 2005-05-19 キュー エル ティー インク. 光感作剤及び皮膚浸透エンハンサーを含有する組成物並びに光力学療法におけるそれらの使用
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
WO2005025508A2 (en) * 2003-09-12 2005-03-24 Bankruptcy Estate Of Ferx, Inc. Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
DE102004028156A1 (de) * 2004-06-09 2006-01-05 Kalbe, Jochen, Dr. Kombination von Radiowellen mit pharmakologisch aktiven Substanzen
US10675298B2 (en) 2006-07-27 2020-06-09 Boston Scientific Scimed Inc. Particles
WO2008014060A2 (en) * 2006-07-27 2008-01-31 Boston Scientific Limited Microparticle
BRPI0716157A2 (pt) * 2006-09-05 2013-09-17 Ct Brasileiro De Pesquisa Fisica Cbpf processo para produÇço microcÁpsulas dotadas de propriedades magnÉticas, produto obtido e mÉtodo para a liberaÇço controlada de substÂncias ativas
RU2373957C2 (ru) 2006-10-13 2009-11-27 Александр Метталинович Тишин Носитель для лекарственных средств и биологически активных веществ для лечения и диагностики и применение его для создания лекарственных средств и способа регулируемой управляемой доставки лекарственного средства или биологически активного вещества с регулируемой десорбцией его
GB0811856D0 (en) 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
JP2012512025A (ja) 2008-12-17 2012-05-31 ダウ コーニング コーポレーション 温度制御放出用のシリケートシェルマイクロカプセルの懸濁液
AU2009346580B2 (en) * 2009-05-21 2014-01-23 Institute Of Life Sciences Water dispersible glyceryl monooleate magnetic nanoparticle formulation
DE102009038239A1 (de) * 2009-08-20 2011-03-03 Siemens Aktiengesellschaft Verfahren und Vorrichtungen zur Untersuchung eines bestimmten Gewebevolumens in einem Körper sowie ein Verfahren und eine Vorrichtung zur Segmentierung des bestimmten Gewebevolumens
PL2519230T3 (pl) 2009-12-31 2019-05-31 Marius Pharmaceuticals Llc Modulacja rozpuszczalności, stabilności, absorpcji, metabolizmu i profilu farmakokinetycznego leków lipofilowych przez sterole
CN105188670B (zh) 2013-03-15 2018-11-02 马留斯医药有限责任公司 乳液制剂
CN110731949A (zh) * 2018-07-19 2020-01-31 康码(上海)生物科技有限公司 一种胶囊及其使用方法
US12403146B2 (en) 2019-10-30 2025-09-02 Marius Pharmaceuticals, Inc. Preferred oral testosterone undecanoate therapy to achieve testosterone replacement treatment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652257A (en) * 1985-03-21 1987-03-24 The United States Of America As Represented By The Secretary Of The Navy Magnetically-localizable, polymerized lipid vesicles and method of disrupting same
FR2650572B1 (de) * 1989-08-02 1991-10-18 Clairefontaine Papeteries
US5542935A (en) * 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5827531A (en) * 1994-12-02 1998-10-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microcapsules and methods for making

Also Published As

Publication number Publication date
EP1077686B1 (de) 2008-08-06
EP1077686A1 (de) 2001-02-28
DE69939258D1 (de) 2008-09-18
ES2310938T3 (es) 2009-01-16
WO1999059556A1 (en) 1999-11-25

Similar Documents

Publication Publication Date Title
DE69939258D1 (de) Mikrokapseln mit extern ausgelöster öffnung
WO2001041847A3 (en) Medicament dispenser
WO2002099457A3 (en) Microchip devices with improved reservoir opening
DE69223021D1 (de) Halbleiteranordnung mit Wärmesenke und Kunststoffkörper und hochzuverlässige Mittel zur elektrischen Verbindung mit der Wärmesenke
ES378408A1 (es) Dispositivo de presentacion visual.
DE69813322D1 (de) Flüssige gonadotropinhaltige Arzneimittel
DE69308489D1 (de) Flüssigkeitsauftragegerät mit zerbrechlicher Ampulle und Gehäuse
ITMI20010005A0 (it) Dispositivo per dosare ed introdurre polvere in capsule di gelatina rigida o simili
DE60015456D1 (de) Bei niedriger Temperatur härtbarer Klebstofffilm und diesen verwendender anisotropischer elektrischleitender Verdunklungsklebefilm
WO2003071967A3 (en) Non-invasive heating of implanted vascular treatment device
DE60009738D1 (de) Verbesserter ausguss und kapsel mit inkorporiertem ausguss
DE69803939D1 (de) Schmelzeinrichtung mit oberflächenbehandeltem al2 o3 und funktionalisierter trennflüssigkeit
ITMI972571A1 (it) Composizioni farmaceutiche in forma di polveri di polimeri reticolati caricati con farmaci e relativo processo di preparazione mediante fluidi supercritici
DE60031914D1 (de) Magnetpulver und isotroper Verbundmagnet
WO2005025469A8 (en) Cold pack
Odenbach Ferrofluids: magnetically controllable liquids
AU2001293882A1 (en) N-alkylglycine trimeres capable of blocking the response to chemical substances,heat stimuli or mediators of neuronal receptor inflammation and compositions containing said trimeres
IT7948963A0 (it) Procedimento per la prechiusura con capsule di vasi contenenti prodotti eventualmente debordanti e dispositivo per realizzarla
ITMI20021402A1 (it) Dispositivo per l'allineamento di capsule divise in due parti
GB1484177A (en) Heat-recoverable cap
GB9912980D0 (en) Liquid cooler and heater
JPWO2021015285A1 (ja) 針付カプセル及び針付カプセルの製造方法
Yassine et al. Magnetically triggered monodispersed nanocomposite fabricated by microfluidic approach for drug delivery
BR9906170A (pt) Registrador de dados que resiste ao esmagamento e ao calor em caso de acidente
JPH0131217Y2 (de)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties