ATE403733T1 - Künstliche säuger chromosome - Google Patents

Künstliche säuger chromosome

Info

Publication number
ATE403733T1
ATE403733T1 AT96927902T AT96927902T ATE403733T1 AT E403733 T1 ATE403733 T1 AT E403733T1 AT 96927902 T AT96927902 T AT 96927902T AT 96927902 T AT96927902 T AT 96927902T AT E403733 T1 ATE403733 T1 AT E403733T1
Authority
AT
Austria
Prior art keywords
chromosomes
mammalian
centromere
mammal
artificial
Prior art date
Application number
AT96927902T
Other languages
English (en)
Inventor
Tsuneko Okazaki
Hiroshi Masumoto
Masashi Ikeno
Howard J Cooke
Brenda Rose Grimes
Original Assignee
Chromo Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chromo Res Inc filed Critical Chromo Res Inc
Application granted granted Critical
Publication of ATE403733T1 publication Critical patent/ATE403733T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/20—Pseudochromosomes, minichrosomosomes
    • C12N2800/206—Pseudochromosomes, minichrosomosomes of yeast origin, e.g. YAC, 2u
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/20—Pseudochromosomes, minichrosomosomes
    • C12N2800/208—Pseudochromosomes, minichrosomosomes of mammalian origin, e.g. minichromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96927902T 1996-08-26 1996-08-26 Künstliche säuger chromosome ATE403733T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1996/002381 WO1998008964A1 (en) 1996-08-26 1996-08-26 Mammalian artificial chromosomes

Publications (1)

Publication Number Publication Date
ATE403733T1 true ATE403733T1 (de) 2008-08-15

Family

ID=14153707

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96927902T ATE403733T1 (de) 1996-08-26 1996-08-26 Künstliche säuger chromosome

Country Status (8)

Country Link
US (2) US6297029B1 (de)
EP (2) EP2060633A1 (de)
JP (1) JP4022835B2 (de)
AT (1) ATE403733T1 (de)
AU (1) AU741864B2 (de)
CA (1) CA2263823C (de)
DE (1) DE69637631D1 (de)
WO (1) WO1998008964A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6077697A (en) * 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
AU741864B2 (en) 1996-08-26 2001-12-13 Masashi Ikeno Mammalian artificial chromosomes
CA2265939A1 (en) * 1996-09-18 1998-03-26 Dnavec Research Inc. Artificial chromosome
WO1998051790A1 (en) 1997-05-13 1998-11-19 Amrad Operations Pty. Ltd. A novel nucleic acid molecule
US7227057B2 (en) 1997-06-03 2007-06-05 Chromatin, Inc. Plant centromere compositions
US7235716B2 (en) 1997-06-03 2007-06-26 Chromatin, Inc. Plant centromere compositions
US7193128B2 (en) 1997-06-03 2007-03-20 Chromatin, Inc. Methods for generating or increasing revenues from crops
US7119250B2 (en) 1997-06-03 2006-10-10 The University Of Chicago Plant centromere compositions
US7989202B1 (en) 1999-03-18 2011-08-02 The University Of Chicago Plant centromere compositions
US6399374B1 (en) * 1999-10-08 2002-06-04 The Johns Hopkins University Converting diploidy to haploidy for genetic diagnosis
US6475794B1 (en) 1999-10-08 2002-11-05 The Johns Hopkins University Converting diploidy to haploidy for genetic diagnosis
IT1316981B1 (it) * 2000-01-05 2003-05-26 Univ Roma Processo di sintesi di dna telomerico di vertebrato, prodotti cosiottenuti e relativi impieghi.
US6936469B2 (en) 2001-03-22 2005-08-30 Chromos Molecular Systems Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US7294511B2 (en) 2001-03-22 2007-11-13 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US6989031B2 (en) 2001-04-02 2006-01-24 Sdgi Holdings, Inc. Hemi-interbody spinal implant manufactured from a major long bone ring or a bone composite
AU2002303277A1 (en) * 2001-04-06 2002-10-21 Vladimir Larionov Artificial chromosomes that can shuttle between bacteria, yeast, and mammalian cells
EP2390256A1 (de) 2001-05-30 2011-11-30 Agrisoma, Inc. Künstliche Pflanzenchromosomen, deren Verwendung und Verfahren zur Herstellung von künstlichen Pflanzenchromosomen
BR0209989A (pt) 2001-05-30 2005-04-12 Chromos Molecular Systems Inc Plataformas baseadas em cromossomas
AU2002332027A1 (en) * 2001-10-04 2003-04-14 The Government Of The United States Of America, As Tandem repeat markers
EP1536007B1 (de) * 2002-09-03 2015-12-30 Japan Science and Technology Agency Künstliches säugerchromosom
US7781190B2 (en) * 2003-07-24 2010-08-24 The University Of Hong Kong Method for constructing and modifying large DNA molecules
WO2005083096A1 (en) 2004-02-23 2005-09-09 Chromatin, Inc. Plants modified with mini-chromosomes
CA2958259C (en) 2004-10-22 2020-06-30 Revivicor, Inc. Ungulates with genetically modified immune systems
US9139849B2 (en) * 2005-04-08 2015-09-22 The United States of America as Represented by the Government of the Department of Health and Human Services Rapid generation of long synthetic centromeric tandem repeats for mammalian artificial chromosome formation
AU2006287553A1 (en) 2005-09-08 2007-03-15 Chromatin, Inc. Plants modified with mini-chromosomes
US8614089B2 (en) * 2007-03-15 2013-12-24 Chromatin, Inc. Centromere sequences and minichromosomes
ES2548377T3 (es) 2008-10-27 2015-10-16 Revivicor, Inc. Ungulados inmunodeprimidos
EP2456894A4 (de) 2009-07-23 2013-09-25 Chromatin Inc Sorghum-zentromer-sequenzen und -minichromosomen
US20140330578A1 (en) * 2012-03-13 2014-11-06 Theodore Pincus Electronic medical history (emh) data management system for standard medical care, clinical medical research, and analysis of long-term outcomes
EP4534674A3 (de) 2016-04-12 2025-06-18 CarryGenes Bioengineering, LLC Verfahren zur erzeugung synthetischer chromosomen zur expression biosynthetischer pfade und verwendungen davon
CA3020984A1 (en) 2016-04-12 2017-10-19 Synploid Biotek, Llc Methods for creating synthetic chromosomes having gene regulatory systems and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270201A (en) 1988-03-24 1993-12-14 The General Hospital Corporation Artificial chromosome vector
CA2042093C (en) 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres
WO1992007080A1 (en) * 1990-10-17 1992-04-30 Board Of Regents, The University Of Texas System A eukaryotic episomal dna cloning and expression vector
WO1993001292A1 (en) * 1991-07-01 1993-01-21 Albert Einstein College Of Medicine Of Yeshiva University Interstitial deletion in chromosomal dna
US5288625A (en) * 1991-09-13 1994-02-22 Biologic Research Center Of The Hungarian Academy Of Sciences Mammalian artificial chromosomes
US5981175A (en) 1993-01-07 1999-11-09 Genpharm Internation, Inc. Methods for producing recombinant mammalian cells harboring a yeast artificial chromosome
GB9410446D0 (en) * 1994-05-25 1994-07-13 Cancer Res Campaign Tech Novel chromosome fragment
US5869294A (en) 1995-06-07 1999-02-09 Case Western Reserve University Method for stably cloning large repeating DNA sequences
US5695967A (en) 1995-06-07 1997-12-09 Case Western Reserve University Method for stably cloning large repeating units of DNA
US6348353B1 (en) 1995-06-07 2002-02-19 Case Western Reserve University Artificial mammalian chromosome
US5721118A (en) 1995-10-31 1998-02-24 The Regents Of The University Of California, San Diego Mammalian artificial chromosomes and methods of using same
US6133503A (en) 1995-10-31 2000-10-17 The Regents Of The University Of California Mammalian artificial chromosomes and methods of using same
US6025155A (en) 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
AU741864B2 (en) 1996-08-26 2001-12-13 Masashi Ikeno Mammalian artificial chromosomes

Also Published As

Publication number Publication date
JP2000517182A (ja) 2000-12-26
US6297029B1 (en) 2001-10-02
CA2263823C (en) 2010-11-23
AU6755096A (en) 1998-03-19
AU741864B2 (en) 2001-12-13
EP2060633A1 (de) 2009-05-20
WO1998008964A1 (en) 1998-03-05
DE69637631D1 (de) 2008-09-18
US20020076811A1 (en) 2002-06-20
JP4022835B2 (ja) 2007-12-19
EP0928339A1 (de) 1999-07-14
EP0928339B1 (de) 2008-08-06
US6569643B2 (en) 2003-05-27
CA2263823A1 (en) 1998-03-05

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