ATE404571T1 - Verfahren zur herstellung von phosphorodiamiditen - Google Patents

Verfahren zur herstellung von phosphorodiamiditen

Info

Publication number
ATE404571T1
ATE404571T1 AT03782645T AT03782645T ATE404571T1 AT E404571 T1 ATE404571 T1 AT E404571T1 AT 03782645 T AT03782645 T AT 03782645T AT 03782645 T AT03782645 T AT 03782645T AT E404571 T1 ATE404571 T1 AT E404571T1
Authority
AT
Austria
Prior art keywords
product
phosphorodiamidites
producing
phosphorodiamidite
polar solvent
Prior art date
Application number
AT03782645T
Other languages
English (en)
Inventor
Christopher John Harris
Sheena Lesley Jackson
David James Wilson
Original Assignee
Rhodia Cons Spec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Cons Spec Ltd filed Critical Rhodia Cons Spec Ltd
Application granted granted Critical
Publication of ATE404571T1 publication Critical patent/ATE404571T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Luminescent Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03782645T 2002-12-24 2003-12-18 Verfahren zur herstellung von phosphorodiamiditen ATE404571T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0230095.2A GB0230095D0 (en) 2002-12-24 2002-12-24 Phosphorodiamidite

Publications (1)

Publication Number Publication Date
ATE404571T1 true ATE404571T1 (de) 2008-08-15

Family

ID=9950379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03782645T ATE404571T1 (de) 2002-12-24 2003-12-18 Verfahren zur herstellung von phosphorodiamiditen

Country Status (11)

Country Link
US (1) US7276620B2 (de)
EP (1) EP1583766B1 (de)
JP (1) JP4511368B2 (de)
KR (1) KR100889897B1 (de)
CN (1) CN100338078C (de)
AT (1) ATE404571T1 (de)
AU (1) AU2003290281A1 (de)
CA (1) CA2511609C (de)
DE (1) DE60322960D1 (de)
GB (1) GB0230095D0 (de)
WO (1) WO2004058779A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015107110A1 (en) * 2014-01-15 2015-07-23 Rhodia Operations Preparation of purified phosphorodiamidite
WO2019131719A1 (ja) * 2017-12-27 2019-07-04 神戸天然物化学株式会社 高脂溶性ホスホラミダイトの製造
CN111057108B (zh) * 2018-10-16 2023-08-15 中国石油化工股份有限公司 一种胺基磷酸酯化合物及其制备方法、用途
CN117362336B (zh) * 2023-09-22 2026-03-13 天津兴博润生物制药有限公司 一种二胺基亚磷酸酯化合物的纯化方法和制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62212395A (ja) 1986-03-11 1987-09-18 Nippon Zeon Co Ltd リンアミド化合物の製造法
DE10208828A1 (de) 2002-03-01 2003-09-11 Bayer Ag Verfahren zur Reduktion von 3-Heteroaryl-3-oxopropionsäurederivaten
US7057062B2 (en) 2002-04-11 2006-06-06 Isis Pharmaceuticals, Inc. Process for manufacturing purified phosphorodiamidite
CN100338076C (zh) 2002-06-13 2007-09-19 罗狄亚公司 制备亚磷酰二胺化合物的方法

Also Published As

Publication number Publication date
KR100889897B1 (ko) 2009-03-20
GB0230095D0 (en) 2003-01-29
EP1583766B1 (de) 2008-08-13
KR20050085831A (ko) 2005-08-29
JP4511368B2 (ja) 2010-07-28
CA2511609A1 (en) 2004-07-15
WO2004058779A1 (en) 2004-07-15
EP1583766A1 (de) 2005-10-12
US7276620B2 (en) 2007-10-02
US20060128951A1 (en) 2006-06-15
DE60322960D1 (de) 2008-09-25
CN1732176A (zh) 2006-02-08
AU2003290281A1 (en) 2004-07-22
CN100338078C (zh) 2007-09-19
CA2511609C (en) 2012-09-25
JP2006512386A (ja) 2006-04-13

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Legal Events

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