ATE404664T1 - Aldehyddehyrdrogenase-gen - Google Patents

Aldehyddehyrdrogenase-gen

Info

Publication number
ATE404664T1
ATE404664T1 AT03798171T AT03798171T ATE404664T1 AT E404664 T1 ATE404664 T1 AT E404664T1 AT 03798171 T AT03798171 T AT 03798171T AT 03798171 T AT03798171 T AT 03798171T AT E404664 T1 ATE404664 T1 AT E404664T1
Authority
AT
Austria
Prior art keywords
aldehyde dehydrogenase
recombinant
dna
expression vector
gene
Prior art date
Application number
AT03798171T
Other languages
English (en)
Inventor
Tatsuo Hoshino
Taro Miyazaki
Teruhide Sugisawa
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of ATE404664T1 publication Critical patent/ATE404664T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT03798171T 2002-09-27 2003-09-22 Aldehyddehyrdrogenase-gen ATE404664T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02021650 2002-09-27

Publications (1)

Publication Number Publication Date
ATE404664T1 true ATE404664T1 (de) 2008-08-15

Family

ID=32039112

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03798171T ATE404664T1 (de) 2002-09-27 2003-09-22 Aldehyddehyrdrogenase-gen

Country Status (9)

Country Link
US (1) US7135315B2 (de)
EP (1) EP1543114B1 (de)
JP (1) JP4528624B2 (de)
KR (1) KR101070110B1 (de)
CN (2) CN100558886C (de)
AT (1) ATE404664T1 (de)
AU (1) AU2003299104A1 (de)
DE (1) DE60322921D1 (de)
WO (1) WO2004029235A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101311562B1 (ko) * 2003-08-14 2013-09-26 디에스엠 아이피 어셋츠 비.브이. 미생물을 이용한 l-아스코르브산의 생산
BRPI0608223A2 (pt) * 2005-02-11 2009-11-24 Dsm Ip Assets Bv gene sms 05
WO2006084725A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene sts 16
WO2006084647A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene vcs 01
WO2006084720A2 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Hpr kinase from gluconobacter oxydan
EP1934344B1 (de) 2005-09-08 2010-02-24 DSM IP Assets B.V. Neues gen sms 37
WO2007028611A2 (en) 2005-09-09 2007-03-15 Dsm Ip Assets B.V. Process for biomass production using a microorganism with a disrupted glucose-dehydrogenase gene (gms 01)
TWI568847B (zh) 2007-03-16 2017-02-01 奇諾麥提卡公司 用於1,4-丁二醇及其前驅物之生物合成的組合物及方法
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
KR20180042467A (ko) 2009-06-04 2018-04-25 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
CN101649323B (zh) * 2009-06-16 2011-06-22 武汉工程大学 按毕赤酵母偏爱密码子设计人乙醛脱氢酶2序列的方法
WO2011047101A1 (en) 2009-10-13 2011-04-21 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
CN102492762A (zh) * 2011-12-09 2012-06-13 天津大学 含有编码山梨酮脱氢酶基因载体的氧化葡糖杆菌的用途
SI2855687T1 (sl) 2012-06-04 2020-09-30 Genomatica, Inc. Mikroorganizmi in metode za proizvodnjo 4-hidroksibutirat, 1,4-butandiola in sorodne spojine
WO2020068900A1 (en) * 2018-09-26 2020-04-02 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
CN111321153B (zh) * 2020-04-26 2021-08-17 广西大学 一种来源于玉米的黑暗响应gd2基因及其应用
KR102460589B1 (ko) 2021-02-17 2022-10-28 주식회사 피코엔텍 글루타치온과 알데히드탈수소효소를 함유하는 숙취해소제
CN115948430B (zh) * 2022-05-26 2024-06-14 南京农业大学 梨醛脱氢酶PusALDH1及其编码基因和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE130030T1 (de) * 1988-01-14 1995-11-15 Hoffmann La Roche Neue coenzym unabhängige l-sorbosone dehydrogenase.
US5437989A (en) 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
US5776742A (en) * 1996-02-19 1998-07-07 Roche Vitamins Inc. Aldehyde dehydrogenase enzyme
EP0922759B1 (de) * 1997-12-01 2004-01-28 F. Hoffmann-La Roche Ag Aldehyd-Dehydrogenase
EP1164192A4 (de) * 1999-03-17 2003-03-05 Fujisawa Pharmaceutical Co SORBITOL-DEHYDROGENASE, DAFüR KODIERENDES GEN UND DEREN VERWENDUNG
JP2002125689A (ja) * 2000-10-25 2002-05-08 Koji Hayade 融合蛋白質
AU1596602A (en) 2000-10-27 2002-05-06 Peter Kratzsch Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Also Published As

Publication number Publication date
EP1543114A2 (de) 2005-06-22
WO2004029235A2 (en) 2004-04-08
KR101070110B1 (ko) 2011-10-05
CN101693896A (zh) 2010-04-14
JP2006500052A (ja) 2006-01-05
US7135315B2 (en) 2006-11-14
AU2003299104A8 (en) 2004-04-19
DE60322921D1 (de) 2008-09-25
CN100558886C (zh) 2009-11-11
CN101693896B (zh) 2012-07-11
EP1543114B1 (de) 2008-08-13
CN1688689A (zh) 2005-10-26
WO2004029235A3 (en) 2004-07-08
JP4528624B2 (ja) 2010-08-18
KR20050052664A (ko) 2005-06-03
AU2003299104A1 (en) 2004-04-19
US20060127994A1 (en) 2006-06-15

Similar Documents

Publication Publication Date Title
DE60322921D1 (de) Aldehyddehyrdrogenase-gen
Pappenberger et al. Industrial production of L-ascorbic acid (vitamin C) and D-isoascorbic acid
Bremus et al. The use of microorganisms in L-ascorbic acid production
Leonard et al. Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli
Yang et al. Industrial fermentation of vitamin C
BRPI0401812A (pt) Métodos para produzir um dicarboxilato de cadaverina, e, náilon
BR0012712B1 (pt) métodos de produção de l-aminoácidos aumentando-se o nadph celular.
DK1309698T3 (da) Cytochrom P450-enzym forbundet med syntesen af delta-12-epoxy-grupper i plantefedtsyrer
ATE326523T1 (de) Verfahren zur fermentativen herstellung von l- methionin
Shi et al. Identification of a novel promoter gHp0169 for gene expression in Gluconobacter oxydans
NO991863L (no) Nye bakteriestammer og bruken derav i fermenteringsprosesser for 2-keto-L-gulonsyreproduksjon
EP0753575A4 (de) NEUARTIGE L-SORBOSEDEHYDROGENASE UND NEUARTIGE LSORBOSEDEHYDROGENASE AUS -i(GLUCONOBACTER OXYDANS)
DE69433112D1 (de) Gene, die verzweigte-alpha-ketosäure-dehydrogenasekomplexe von streptomyces avermitius kodieren
ATE318907T1 (de) Erhöhte herstellung von 2-keto-l-gulonsäure
ATE451468T1 (de) Biosynthese von polyketidsynthase-substrate
EA200700287A1 (ru) Улучшенные ферменты
AR122916A1 (es) Glutamato deshidrogenasa modificada y uso de la misma
AR034550A1 (es) Un polinucleotido, un vector, una celula hospedadora, un polipeptido, ml-236b, un metodo para su produccion, un metodo para fabricar pravastatina, un anticuerpo reactivo.
ATE220104T1 (de) Expressionssystem zur produktion von proteinen
ATE417117T1 (de) Verfahren zur herstellung von 2-keto-l-gulonsäure
ATE323172T1 (de) Herstellung von l-ascorbinsäure und d- erythorbinsäure
Kudo et al. Rapid Identification of γ-Butyrolactone Signalling Molecules in Diverse Actinomycetes Using Resin-Assisted Isolation and Chemoenzymatic Synthesis
Liu et al. Coding Synthetic Chemistry Strategies into Bacterial Designer Cells
Niwa et al. Method for producing 2-keto-L-gulonic acid
WO2006084749A3 (en) Rcs 02, a novel gene involved in the biosynthesis of vitamin c

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties