ATE405339T1 - Fluidisches misch- und reaktionsverfahren mit verwendung einer mikrovorrichtung, und mikrovorrichtung - Google Patents

Fluidisches misch- und reaktionsverfahren mit verwendung einer mikrovorrichtung, und mikrovorrichtung

Info

Publication number
ATE405339T1
ATE405339T1 AT04020419T AT04020419T ATE405339T1 AT E405339 T1 ATE405339 T1 AT E405339T1 AT 04020419 T AT04020419 T AT 04020419T AT 04020419 T AT04020419 T AT 04020419T AT E405339 T1 ATE405339 T1 AT E405339T1
Authority
AT
Austria
Prior art keywords
micro device
fluids
microchannel
reaction method
fluidic mixing
Prior art date
Application number
AT04020419T
Other languages
English (en)
Inventor
Satoru Komori
Yasumasa Ito
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Application granted granted Critical
Publication of ATE405339T1 publication Critical patent/ATE405339T1/de

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/84—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations for material continuously moving through a tube, e.g. by deforming the tube
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/65—Mixers with shaking, oscillating, or vibrating mechanisms the materials to be mixed being directly submitted to a pulsating movement, e.g. by means of an oscillating piston or air column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/86—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with vibration of the receptacle or part of it
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/211—Measuring of the operational parameters
    • B01F35/2114—Speed of feeding material, e.g. bands or strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0436—Operational information
    • B01F2215/0454—Numerical frequency values
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00822—Metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00824—Ceramic
    • B01J2219/00828—Silicon wafers or plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00831—Glass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00833—Plastic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/0086—Dimensions of the flow channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00954—Measured properties
    • B01J2219/00957—Compositions or concentrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00954—Measured properties
    • B01J2219/00959—Flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00993—Design aspects
    • B01J2219/00995—Mathematical modeling
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S366/00—Agitating
    • Y10S366/04—Micromixers: with application of energy to influence mixing/agitation, e.g. magnetic, electrical, e-m radiation, particulate radiation, or ultrasound

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)
AT04020419T 2003-08-29 2004-08-27 Fluidisches misch- und reaktionsverfahren mit verwendung einer mikrovorrichtung, und mikrovorrichtung ATE405339T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003307065A JP2005077219A (ja) 2003-08-29 2003-08-29 マイクロデバイスの流体混合反応促進方法及びマイクロデバイス

Publications (1)

Publication Number Publication Date
ATE405339T1 true ATE405339T1 (de) 2008-09-15

Family

ID=34101251

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04020419T ATE405339T1 (de) 2003-08-29 2004-08-27 Fluidisches misch- und reaktionsverfahren mit verwendung einer mikrovorrichtung, und mikrovorrichtung

Country Status (6)

Country Link
US (1) US7401970B2 (de)
EP (1) EP1510250B1 (de)
JP (1) JP2005077219A (de)
CN (1) CN100408153C (de)
AT (1) ATE405339T1 (de)
DE (1) DE602004015899D1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090268548A1 (en) * 2005-08-11 2009-10-29 Eksigent Technologies, Llc Microfluidic systems, devices and methods for reducing diffusion and compliance effects at a fluid mixing region
US20080080302A1 (en) * 2006-09-29 2008-04-03 Fujifilm Corporation Droplet mixing method and apparatus
JP4852399B2 (ja) * 2006-11-22 2012-01-11 富士フイルム株式会社 二液合流装置
JP5262064B2 (ja) * 2007-10-30 2013-08-14 富士ゼロックス株式会社 マイクロリアクターを用いた反応方法及びマイクロリアクター
JP2009226261A (ja) 2008-03-19 2009-10-08 Fujifilm Corp 液体混合方法および液体混合装置
JP5322475B2 (ja) * 2008-03-31 2013-10-23 富士フイルム株式会社 微粒子の製造方法及び装置
JP5081845B2 (ja) * 2009-02-10 2012-11-28 株式会社日立製作所 粒子製造装置
FR2955508B1 (fr) 2010-01-25 2012-03-30 Corning Inc Microreacteurs avec dispositif microfluidique plan et systeme d'application d'ultrasons ; mise en oeuvre de reactions chimiques en leur sein
US10080997B2 (en) * 2012-03-16 2018-09-25 Versitech Limited System and method for generation of emulsions with low interfacial tension and measuring frequency vibrations in the system
EP2705899A1 (de) * 2012-09-07 2014-03-12 Fluigent Mikrofluidisches System mit einer homogenisierenden Komponente
US11191886B2 (en) * 2013-06-14 2021-12-07 The Cleveland Clinic Foundation Motion-assisted systems, devices and methods for minimizing obstruction of medical devices
US11056215B2 (en) * 2016-08-15 2021-07-06 International Business Machines Corporation Performing chemical textual analysis to discover dangerous chemical pathways
EP3592405B1 (de) * 2017-03-10 2026-05-06 Enable Injections, Inc. Rekonstitutionsvorrichtung, system und verfahren
CN110637222A (zh) * 2017-05-26 2019-12-31 文塔纳医疗系统公司 非接触式、在载玻片上的流体混合
CN111122707B (zh) * 2019-08-30 2021-07-02 厦门大学 微流控芯片能量传递效率测量设备、方法和实验设备
CN110918021A (zh) * 2019-11-21 2020-03-27 南京先进生物材料与过程装备研究院有限公司 一种微反应装置及用其制备二甲苯甲醛树脂的方法
CN111214987A (zh) * 2019-11-28 2020-06-02 江西艾迪尔新能源有限公司 一种高效率的氯代脂肪酸甲酯生产设备

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2585103A (en) * 1948-03-08 1952-02-12 Otis A Brown Apparatus for ultrasonic treatment of liquids
US2701708A (en) * 1952-09-26 1955-02-08 Us Rubber Co Method and apparatus for producing latex foam
US3153530A (en) * 1959-07-06 1964-10-20 Albert G Bodine Apparatus for generating and transmitting sonic vibrations
US3165299A (en) * 1962-08-13 1965-01-12 Cavitron Ultrasonics Inc Ultrasonic mixing apparatus
US3622286A (en) * 1970-07-13 1971-11-23 Lloyd E Gaddy Vibratory apparatus for working particulate solids
US3743523A (en) * 1971-08-04 1973-07-03 A Bodine Method for the sonic treating of food material
US3780992A (en) * 1972-07-17 1973-12-25 Department Of Health Education Vibrating pipette probe mixer
US4352570A (en) * 1980-05-27 1982-10-05 Applied Plastics Co., Inc. Vibratory treatment apparatus and method
DE3037187A1 (de) * 1980-10-02 1982-05-06 Bergwerksverband Gmbh, 4300 Essen Verfahren zur desorption von beladenem festen adsorbensmaterial
US4610546A (en) * 1984-12-31 1986-09-09 Technicon Instruments Corporation Apparatus and method for self-resonant vibrational mixing
ES2113186T3 (es) * 1994-02-02 1998-04-16 Medical Projects Hb Procedimiento y aparato para la manipulacion y dosificacion de un aditivo durante la recogida de un liquido.
DE19909180A1 (de) 1998-03-04 1999-09-09 Inst Mikrotechnik Mainz Gmbh Verfahren zur Durchführung chemischer Umsetzungen in einem Mikroreaktor und solch ein Mikroreaktor
JPH11347392A (ja) * 1998-06-11 1999-12-21 Hitachi Ltd 攪拌装置
DE10123092B4 (de) 2001-05-07 2005-02-10 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Verfahren und statischer Mischer zum Mischen mindestens zweier Fluide
US6939032B2 (en) * 2001-10-25 2005-09-06 Erie Scientific Company Cover slip mixing apparatus
JP4221184B2 (ja) * 2002-02-19 2009-02-12 日本碍子株式会社 マイクロ化学チップ
US20040257907A1 (en) * 2003-06-19 2004-12-23 Agency For Science, Technology And Research Method and apparatus for mixing fluids

Also Published As

Publication number Publication date
US7401970B2 (en) 2008-07-22
EP1510250A3 (de) 2005-11-23
EP1510250B1 (de) 2008-08-20
JP2005077219A (ja) 2005-03-24
CN1597077A (zh) 2005-03-23
CN100408153C (zh) 2008-08-06
EP1510250A2 (de) 2005-03-02
US20050058014A1 (en) 2005-03-17
DE602004015899D1 (de) 2008-10-02

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