ATE406575T1 - Verfahren zur erkennung von medikamentenempfindlichkeit in patienten mit entzündungskrankheiten - Google Patents
Verfahren zur erkennung von medikamentenempfindlichkeit in patienten mit entzündungskrankheitenInfo
- Publication number
- ATE406575T1 ATE406575T1 AT02762680T AT02762680T ATE406575T1 AT E406575 T1 ATE406575 T1 AT E406575T1 AT 02762680 T AT02762680 T AT 02762680T AT 02762680 T AT02762680 T AT 02762680T AT E406575 T1 ATE406575 T1 AT E406575T1
- Authority
- AT
- Austria
- Prior art keywords
- expression profile
- sample
- patients
- inflammatory diseases
- drug sensitivity
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 208000027866 inflammatory disease Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000035945 sensitivity Effects 0.000 title 1
- 230000014509 gene expression Effects 0.000 abstract 5
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/947,991 US7384736B2 (en) | 2001-09-06 | 2001-09-06 | Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406575T1 true ATE406575T1 (de) | 2008-09-15 |
Family
ID=25487094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02762680T ATE406575T1 (de) | 2001-09-06 | 2002-09-02 | Verfahren zur erkennung von medikamentenempfindlichkeit in patienten mit entzündungskrankheiten |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7384736B2 (de) |
| EP (1) | EP1428023B1 (de) |
| JP (1) | JP2005502345A (de) |
| AT (1) | ATE406575T1 (de) |
| AU (1) | AU2002328110B2 (de) |
| CA (1) | CA2457476A1 (de) |
| DE (1) | DE60228592D1 (de) |
| DK (1) | DK1428023T3 (de) |
| WO (1) | WO2003021261A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1233651A1 (de) * | 2000-04-07 | 2002-08-21 | Ibiden Co., Ltd. | Keramisches heizelement |
| US7198895B2 (en) * | 2000-11-14 | 2007-04-03 | Mohanlal Ramon W | In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals |
| US6893828B2 (en) * | 2001-09-06 | 2005-05-17 | Decode Genetics Ehf. | Methods for producing ex vivo models for inflammatory disease and uses thereof |
| US7384736B2 (en) * | 2001-09-06 | 2008-06-10 | Decode Genetics Ehf. | Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease |
| US6964850B2 (en) * | 2001-11-09 | 2005-11-15 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| CA2469459C (en) * | 2001-12-07 | 2011-10-18 | University Of Wyoming | Methods and compositions for the diagnosis of asthma |
| US7655397B2 (en) * | 2002-04-25 | 2010-02-02 | The United States Of America As Represented By The Department Of Health And Human Services | Selections of genes and methods of using the same for diagnosis and for targeting the therapy of select cancers |
| US7774143B2 (en) * | 2002-04-25 | 2010-08-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Methods for analyzing high dimensional data for classifying, diagnosing, prognosticating, and/or predicting diseases and other biological states |
| MXPA05005073A (es) * | 2002-11-12 | 2005-11-17 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
| AU2003900639A0 (en) * | 2003-02-12 | 2003-02-27 | G2 Therapies Ltd | Novel method of treating inflammatory diseases |
| WO2004107240A1 (de) * | 2003-05-30 | 2004-12-09 | Thiesen Hans-Juergen | Verfahren zur beurteilung des ansprechverhaltens eines individuums auf antirheumatika |
| WO2004108960A2 (en) * | 2003-06-09 | 2004-12-16 | Decode Genetics Ehf. | Methods for predicting drug efficacy in patients afflicted with hypertension |
| BRPI0416945A (pt) * | 2003-11-25 | 2007-02-13 | Novartis Ag | biomarcadores para a eficácia do tratamento com hormÈnio paratiróide e calcitonina |
| EP1832993B1 (de) * | 2006-03-06 | 2009-02-25 | General Electric Company | Automatische Kalibrierung der Sensibilität einer Person gegenüber einem Arzneimittel |
| WO2008120659A1 (ja) * | 2007-03-30 | 2008-10-09 | Oji Paper Co., Ltd. | 遺伝子発現情報を用いた植物の形質を判定もしくは予測する方法 |
| JP2010539890A (ja) | 2007-09-14 | 2010-12-24 | ユニヴァーシティ オブ サウス フロリダ | 放射線治療の応答を予測するための遺伝子シグネチャー |
| WO2009078793A1 (en) | 2007-12-14 | 2009-06-25 | Index Pharmaceuticals Ab | Method for predicting the response to a therapy |
| US8577620B2 (en) * | 2008-03-27 | 2013-11-05 | Gus J. Slotman | Methods for assessing drug efficacy and response of patient to therapy |
| BRPI0906261A2 (pt) * | 2008-03-31 | 2015-07-07 | Genentech Inc | "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" |
| RU2578468C2 (ru) | 2010-12-16 | 2016-03-27 | Дженентек, Инк. | Способы диагностики и лечения, связанные с ингибированием th2 |
| US20150292012A1 (en) * | 2012-10-26 | 2015-10-15 | Case Western Reserve University | Biomarkers for nod2 and/or rip2 activity related application |
| CN105308460A (zh) * | 2013-05-02 | 2016-02-03 | 天主教大学基金会 | 个性化药物 |
| CL2015001420A1 (es) * | 2015-05-26 | 2015-10-02 | Univ Chile | Método ex vivo y kit predictor de respuesta a tratamiento con glucocorticoides (gc) en pacientes portadores de enfermedades inflamatorias, basado en la cuantificación de la razón de cambio de los niveles de las isoformas del receptor de gc. |
| ES2971091T3 (es) * | 2017-08-30 | 2024-06-03 | Bristol Myers Squibb Co | Un método para supervisar las respuestas farmacodinámicas mediadas por la administración de glucocorticoides in vivo |
| US12191023B1 (en) | 2018-03-30 | 2025-01-07 | Flagship Pioneering Innovations Vi, Llc | Systems and methods for patient targeted therapy development |
| CN108830040B (zh) * | 2018-06-07 | 2021-06-15 | 中南大学 | 一种基于细胞系和药物相似性网络的药物敏感性预测方法 |
| WO2022098882A1 (en) * | 2020-11-04 | 2022-05-12 | Massachusetts Institute Of Technology | Methods for identifying drivers of immune responses using molecular expression signatures of immunomodulating agents |
| US12512218B2 (en) * | 2021-03-12 | 2025-12-30 | PulManage, Inc. | Spirometry data systems, methods, and apparatuses |
| US20250188514A1 (en) * | 2023-12-11 | 2025-06-12 | King Faisal Specialist Hospital & Research Centre | Method for determining the activity of a drug or drug candidate under conditions of microgravity |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6801859B1 (en) | 1998-12-23 | 2004-10-05 | Rosetta Inpharmatics Llc | Methods of characterizing drug activities using consensus profiles |
| US6692916B2 (en) * | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US7198895B2 (en) * | 2000-11-14 | 2007-04-03 | Mohanlal Ramon W | In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals |
| WO2002059367A2 (en) * | 2000-11-30 | 2002-08-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Diagnostic microarray for inflammatory bowel disease, crohn's disease and ulcerative colitis |
| US20030154032A1 (en) * | 2000-12-15 | 2003-08-14 | Pittman Debra D. | Methods and compositions for diagnosing and treating rheumatoid arthritis |
| WO2002049634A2 (en) * | 2000-12-20 | 2002-06-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dissociated glucocorticoid receptor antagonists for the treatment of clucocorticoid associated side-effect |
| US7384736B2 (en) | 2001-09-06 | 2008-06-10 | Decode Genetics Ehf. | Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease |
| US6893828B2 (en) * | 2001-09-06 | 2005-05-17 | Decode Genetics Ehf. | Methods for producing ex vivo models for inflammatory disease and uses thereof |
| US20040116462A1 (en) * | 2002-12-12 | 2004-06-17 | Mitsunori Ono | Indolizine compounds |
| WO2004108960A2 (en) * | 2003-06-09 | 2004-12-16 | Decode Genetics Ehf. | Methods for predicting drug efficacy in patients afflicted with hypertension |
-
2001
- 2001-09-06 US US09/947,991 patent/US7384736B2/en not_active Expired - Fee Related
-
2002
- 2002-09-02 DE DE60228592T patent/DE60228592D1/de not_active Expired - Lifetime
- 2002-09-02 DK DK02762680T patent/DK1428023T3/da active
- 2002-09-02 WO PCT/IB2002/003613 patent/WO2003021261A2/en not_active Ceased
- 2002-09-02 EP EP02762680A patent/EP1428023B1/de not_active Expired - Lifetime
- 2002-09-02 AT AT02762680T patent/ATE406575T1/de not_active IP Right Cessation
- 2002-09-02 JP JP2003525293A patent/JP2005502345A/ja active Pending
- 2002-09-02 CA CA002457476A patent/CA2457476A1/en not_active Abandoned
- 2002-09-02 AU AU2002328110A patent/AU2002328110B2/en not_active Ceased
- 2002-09-03 US US10/234,652 patent/US7148008B2/en not_active Expired - Fee Related
-
2006
- 2006-11-03 US US11/592,699 patent/US20070054309A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030134776A1 (en) | 2003-07-17 |
| WO2003021261A2 (en) | 2003-03-13 |
| US7148008B2 (en) | 2006-12-12 |
| DE60228592D1 (de) | 2008-10-09 |
| WO2003021261A3 (en) | 2003-11-20 |
| EP1428023B1 (de) | 2008-08-27 |
| DK1428023T3 (da) | 2009-01-19 |
| JP2005502345A (ja) | 2005-01-27 |
| US20030113831A1 (en) | 2003-06-19 |
| AU2002328110B2 (en) | 2007-01-25 |
| EP1428023A2 (de) | 2004-06-16 |
| US7384736B2 (en) | 2008-06-10 |
| CA2457476A1 (en) | 2003-03-13 |
| US20070054309A1 (en) | 2007-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |